SCHEMBL8046992

SCHEMBL8046992

O=S(=O)(c1[c]ccc(S(=O)(=O)c2ccccc2)c1)c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 5/20 0.54
ALDH1A1 P00352 3/20 0.43
POLB P06746 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
MAPT P10636 1/20 0.43
LMNA P02545 2/20 0.41
THRB P10828 1/20 0.41
TSHR P16473 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
HTR2C P28335 2/20 0.40
HTR2B P41595 1/20 0.40
PNMT P11086 1/20 0.38
GAA P10253 1/20 0.37
GFER P55789 1/20 0.37
KMT2A Q03164 1/20 0.37
HTR2A P28223 1/20 0.36
KCNH2 Q12809 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8046870 0.90 GAA (0.50) HTR6ALDH1A1POLBSMN1; SMN2MAPT
SCHEMBL9319768 0.87 HTR6 (0.43) HTR6ALDH1A1POLBSMN1; SMN2MAPT
SCHEMBL9322085 0.87 HTR6 (0.48) HTR6ALDH1A1POLBSMN1; SMN2MAPT
SCHEMBL8059424 0.82 ALDH1A1 (0.47) HTR6ALDH1A1POLBSMN1; SMN2MAPT
SCHEMBL8059405 0.81 ALDH1A1 (0.57) HTR6ALDH1A1POLBSMN1; SMN2MAPT
SCHEMBL8058723 0.81 GAA (0.57) ALDH1A1POLBSMN1; SMN2MAPTGAA
SCHEMBL5132685 0.81 LMNA (0.46) HTR6ALDH1A1POLBLMNATSHR
SCHEMBL7474970 0.79 HTR6 (0.52) HTR6ALDH1A1POLBSMN1; SMN2MAPT
SCHEMBL11436654 0.79 HTR6 (0.52) HTR6ALDH1A1POLBSMN1; SMN2MAPT
SCHEMBL315684 0.78 HTR6 (0.54) HTR6ALDH1A1POLBSMN1; SMN2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6040470-A DERIVATIVES OF 1-ORGANOETHER,-ESTER OR SULFONE-2,4-BIS-PHENYLSULFONYL)BENZENE IN AN AQUEOUS DEVELOPER SLURRY TO PREVENT DETERIORATION OF DISPERSION DUE TO HYDRATION; HIGHLY SENSITIVE; LESS SURFACE BLUSHING; STORAGE STABILITY OF IMAGE SANKO KAIHATSU KAGAKU KENKYUSHO (JP) 2000-03-21 US claimed
EP-0791578-B1 Sulfonyl compound and thermalsensitive recording medium using the same SANKO KAIHATSU KAGAKU KENK (JP) 1999-11-10 EP claimed
EP-0791578-A2 Sulfonyl compound and thermalsensitive recording medium using the same Sanko Kaihatsu Kagaku Kenkyusho (JP) 1997-08-27 EP claimed
US-6040470-A DERIVATIVES OF 1-ORGANOETHER,-ESTER OR SULFONE-2,4-BIS-PHENYLSULFONYL)BENZENE IN AN AQUEOUS DEVELOPER SLURRY TO PREVENT DETERIORATION OF DISPERSION DUE TO HYDRATION; HIGHLY SENSITIVE; LESS SURFACE BLUSHING; STORAGE STABILITY OF IMAGE SANKO KAIHATSU KAGAKU KENKYUSHO (JP) 2000-03-21 US disclosed
EP-0791578-B1 Sulfonyl compound and thermalsensitive recording medium using the same SANKO KAIHATSU KAGAKU KENK (JP) 1999-11-10 EP disclosed
US-5840652-A HIGH SENSITIVITY, STORAGE STABILITY SANKO KAIHATSU KAGAKU KENKYUSHO (JP) 1998-11-24 US disclosed
EP-0791578-A2 Sulfonyl compound and thermalsensitive recording medium using the same Sanko Kaihatsu Kagaku Kenkyusho (JP) 1997-08-27 EP disclosed