SCHEMBL8059424

SCHEMBL8059424

Cc1ccc(C)c(S(=O)(=O)c2[c]ccc(S(=O)(=O)c3ccccc3)c2)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
MAPT P10636 2/20 0.47
POLB P06746 1/20 0.47
SFRP1 Q8N474 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
HTR6 P50406 2/20 0.39
HTT P42858 5/20 0.39
TSHR P16473 2/20 0.39
LMNA P02545 2/20 0.39
TDP1 Q9NUW8 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
KMT2A Q03164 2/20 0.38
KDM4E B2RXH2 2/20 0.37
APAF1 O14727 1/20 0.37
F2 P00734 1/20 0.37
XBP1 P17861 1/20 0.37
GAA P10253 2/20 0.37
UBE2N P61088 1/20 0.36
CYP1A2 P05177 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8061637 0.90 KMT2A (0.42) ALDH1A1SMN1; SMN2MAPTHTTTSHR
SCHEMBL8046870 0.85 GAA (0.50) ALDH1A1SMN1; SMN2MAPTPOLBL3MBTL1
SCHEMBL4403008 0.82 ALDH1A1 (0.57) ALDH1A1SMN1; SMN2MAPTPOLBSFRP1
SCHEMBL757794 0.82 ALDH1A1 (0.51) ALDH1A1SMN1; SMN2MAPTPOLBSFRP1
SCHEMBL30963734 0.82 ALDH1A1 (0.51) ALDH1A1SMN1; SMN2MAPTPOLBSFRP1
SCHEMBL8046992 0.82 HTR6 (0.54) ALDH1A1SMN1; SMN2MAPTPOLBHTR6
SCHEMBL8058723 0.79 GAA (0.57) ALDH1A1SMN1; SMN2MAPTPOLBL3MBTL1
SCHEMBL4402282 0.78 ALDH1A1 (0.53) ALDH1A1SMN1; SMN2MAPTPOLBSFRP1
SCHEMBL9322085 0.77 HTR6 (0.48) ALDH1A1SMN1; SMN2MAPTPOLBSFRP1
SCHEMBL11599302 0.75 ALDH1A1 (0.66) ALDH1A1SMN1; SMN2MAPTPOLBSFRP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6040470-A DERIVATIVES OF 1-ORGANOETHER,-ESTER OR SULFONE-2,4-BIS-PHENYLSULFONYL)BENZENE IN AN AQUEOUS DEVELOPER SLURRY TO PREVENT DETERIORATION OF DISPERSION DUE TO HYDRATION; HIGHLY SENSITIVE; LESS SURFACE BLUSHING; STORAGE STABILITY OF IMAGE SANKO KAIHATSU KAGAKU KENKYUSHO (JP) 2000-03-21 US disclosed
EP-0791578-B1 Sulfonyl compound and thermalsensitive recording medium using the same SANKO KAIHATSU KAGAKU KENK (JP) 1999-11-10 EP disclosed
US-5840652-A HIGH SENSITIVITY, STORAGE STABILITY SANKO KAIHATSU KAGAKU KENKYUSHO (JP) 1998-11-24 US disclosed
EP-0791578-A2 Sulfonyl compound and thermalsensitive recording medium using the same Sanko Kaihatsu Kagaku Kenkyusho (JP) 1997-08-27 EP disclosed