SCHEMBL804993

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13023890	0.93	TSHR (0.55)	TSHRAKT1AKT2ALDH1A1LMNA
	SCHEMBL13052947	0.89	AKT1 (0.49)	TSHRAKT1AKT2ALDH1A1LMNA
	SCHEMBL13052976	0.88	TSHR (0.46)	TSHRAKT1AKT2ALDH1A1LMNA
	SCHEMBL14947878	0.87	ALDH1A1 (0.48)	TSHRAKT1AKT2ALDH1A1LMNA
	SCHEMBL13052968	0.87	AKT1 (0.48)	TSHRAKT1AKT2ALDH1A1LMNA
	SCHEMBL12854007	0.87	AKT1 (0.51)	TSHRAKT1AKT2ALDH1A1LMNA
	SCHEMBL64513	0.87	TSHR (0.45)	TSHRAKT1AKT2ALDH1A1LMNA
	SCHEMBL804796	0.85	AKT1 (0.47)	TSHRAKT1AKT2ALDH1A1LMNA
	SCHEMBL13052979	0.83	AKT1 (0.39)	TSHRAKT1AKT2ALDH1A1PDE4B
	SCHEMBL12156625	0.83	MEN1 (0.45)	TSHRAKT1AKT2ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 165 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.