SCHEMBL804803

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL804871	0.96	NPC1 (0.37)	MAPTKDM4EHPGDNPC1ALDH1A1
	SCHEMBL13943358	0.94	PLA2G2A (0.37)	MAPTKDM4EHPGDNPC1ALDH1A1
	SCHEMBL804805	0.92	MAOA (0.38)	MAPTKDM4EHPGDNPC1ALDH1A1
	SCHEMBL804449	0.92	BTK (0.38)	MAPTKDM4EHPGDNPC1ALDH1A1
	SCHEMBL2628387	0.92	MAOA (0.38)	MAPTKDM4EHPGDSMN1; SMN2PLA2G2A
	SCHEMBL804465	0.91	KDM4E (0.35)	MAPTKDM4EHPGDNPC1ALDH1A1
	SCHEMBL16356757	0.90	BTK (0.39)	MAPTKDM4EHPGDNPC1ALDH1A1
	SCHEMBL804547	0.89	PLA2G2A (0.38)	MAPTKDM4EHPGDNPC1ALDH1A1
	SCHEMBL804786	0.89	BTK (0.39)	MAPTKDM4EHPGDNPC1ALDH1A1
	SCHEMBL804795	0.89	BTK (0.37)	MAPTKDM4EHPGDNPC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.