Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 2/20 | 0.33 |
| ▸ | BTK | Q06187 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ATP4A | P20648 | 1/20 | 0.32 |
| ▸ | ATP4B | P51164 | 1/20 | 0.32 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL970040 | 0.87 | ALDH1A1 (0.38) | MEN1KMT2AKDM4EALDH1A1HTT | |
| SCHEMBL8031000 | 0.81 | ATP4A (0.38) | MEN1KMT2AKDM4EALDH1A1RAB9A | |
| SCHEMBL970413 | 0.70 | CRHR1 (0.36) | MEN1KMT2AALDH1A1HTTPOLB | |
| SCHEMBL968700 | 0.69 | KMT2A (0.33) | MEN1KMT2AALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL3330603 | 0.69 | ALOX5 (0.33) | MEN1KMT2AKDM4EALDH1A1POLB | |
| SCHEMBL969679 | 0.68 | RXFP1 (0.41) | MEN1KMT2AALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL3324746 | 0.67 | PTGS2 (0.35) | MEN1KMT2AKDM4EALDH1A1GAA | |
| SCHEMBL3325965 | 0.67 | KMT2A (0.38) | MEN1KMT2AKDM4EALDH1A1HTT | |
| SCHEMBL3326254 | 0.65 | CRHR1 (0.32) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3325859 | 0.64 | AMY1A (0.32) | MEN1KMT2AKDM4EALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009070584-A1 | ARYL AND HETEROARYL FUSED IMIDAZO[1,5-A]PYRAZINES AS INHIBITORS OF PHOSPHODIESTERASE 10 | WYETH (US) | 2009-06-04 | — | — | WO | disclosed |