Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8050654 | 0.83 | NPC1 (0.36) | MEN1NPC1AGTR1RAB9AKMT2A | |
| SCHEMBL8045179 | 0.81 | TSHR (0.33) | MEN1KMT2A | |
| SCHEMBL8041815 | 0.79 | MEN1 (0.33) | MEN1NPC1AGTR1RAB9AKMT2A | |
| SCHEMBL8044746 | 0.77 | RXRA (0.40) | MEN1NPC1AGTR1RAB9AKMT2A | |
| SCHEMBL8034182 | 0.76 | NPC1 (0.55) | MEN1NPC1AGTR1RAB9AKMT2A | |
| SCHEMBL8043693 | 0.76 | PIP4K2C (0.38) | MEN1KMT2A | |
| SCHEMBL8046664 | 0.75 | CA12 (0.42) | MEN1KMT2A | |
| SCHEMBL8044376 | 0.74 | CA12 (0.33) | — | |
| SCHEMBL8051552 | 0.74 | KDM4E (0.53) | MEN1NPC1RAB9AKMT2A | |
| SCHEMBL8045938 | 0.71 | HSD17B10 (0.40) | MEN1NPC1AGTR1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |
| WO-1998027092-A1 | THIAZOLE COMPOUNDS AND METHODS OF MODULATING SIGNAL TRANSDUCTION | SUGEN, INC. (US) | 1998-06-25 | — | — | WO | disclosed |