SCHEMBL804987

SCHEMBL804987

c1cc(-c2cc(-c3cccc(-c4ccc5oc6ccccc6c5c4)c3)cc(-n3c4cccnc4c4ncccc43)c2)cc(-c2ccc3oc4ccccc4c3c2)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.40
NPC1 O15118 2/20 0.40
PLA2G2A P14555 4/20 0.38
PLA2G4A P47712 4/20 0.38
PLA2G10 O15496 1/20 0.38
KDM4E B2RXH2 3/20 0.35
ALDH1A1 P00352 3/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
HPGD P15428 1/20 0.35
RAB9A P51151 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
CASP3 P42574 1/20 0.34
SENP7 Q9BQF6 1/20 0.34
SENP6 Q9GZR1 1/20 0.34
CHEK2 O96017 1/20 0.34
AHR P35869 1/20 0.33
PRKDC P78527 1/20 0.32
ALOX5 P09917 1/20 0.32
LMNA P02545 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL804869 0.98 MAPT (0.42) MAPTNPC1PLA2G2APLA2G4APLA2G10
SCHEMBL804971 0.95 MAPT (0.40) MAPTNPC1PLA2G2APLA2G4APLA2G10
SCHEMBL804887 0.91 NPC1 (0.39) MAPTNPC1PLA2G2APLA2G4APLA2G10
SCHEMBL804974 0.91 NPC1 (0.39) MAPTNPC1PLA2G2APLA2G4APLA2G10
SCHEMBL13943360 0.89 MAPT (0.36) MAPTNPC1PLA2G2APLA2G4APLA2G10
SCHEMBL15855406 0.88 PLA2G2A (0.36) MAPTNPC1PLA2G2APLA2G4APLA2G10
SCHEMBL804766 0.87 PGR (0.33) MAPTNPC1PLA2G2APLA2G4APLA2G10
SCHEMBL805988 0.87 PLA2G10 (0.32) MAPTNPC1PLA2G2APLA2G4APLA2G10
SCHEMBL2628348 0.86 NPC1 (0.35) MAPTNPC1PLA2G2APLA2G4APLA2G10
SCHEMBL804790 0.86 PLA2G2A (0.44) MAPTNPC1PLA2G2APLA2G4APLA2G10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8471008-B2 Material for organic electroluminescent element and organic electroluminescent element employing the same IDEMITSU KOSAN CO., LTD. (JP) 2013-06-25 US disclosed
US-8471008-B2 Material for organic electroluminescent element and organic electroluminescent element employing the same IDEMITSU KOSAN CO., LTD. (JP) 2013-06-25 US disclosed
US-20120068164-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT AND ORGANIC ELECTROLUMINESCENT ELEMENT EMPLOYING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-03-22 US disclosed
US-8080658-B2 Material for organic electroluminescent element and organic electroluminescent element employing the same IDEMITSU KOSAN CO., LTD. (JP) 2011-12-20 US disclosed
US-8080658-B2 Material for organic electroluminescent element and organic electroluminescent element employing the same IDEMITSU KOSAN CO., LTD. (JP) 2011-12-20 US disclosed
US-7968213-B2 Material for organic electroluminescence device and organic electroluminescence device utilizing the same IDEMITSU KOSAN CO., LTD. (JP) 2011-06-28 US disclosed
US-7968213-B2 Material for organic electroluminescence device and organic electroluminescence device utilizing the same IDEMITSU KOSAN CO., LTD. (JP) 2011-06-28 US disclosed
US-20090030202-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT AND ORGANIC ELECTROLUMINESCENT ELEMENT EMPLOYING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2009-01-29 US disclosed
US-20090030202-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT AND ORGANIC ELECTROLUMINESCENT ELEMENT EMPLOYING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2009-01-29 US disclosed
US-20090017331-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE UTILIZING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2009-01-15 US disclosed
US-20090017331-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE UTILIZING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2009-01-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120068164-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT AND ORGANIC ELECTROLUMINESCENT ELEMENT EMPLOYING THE SAME EMC2, L1CAM, EMC1 MAPT 150/4885NPC1 3452/4885PLA2G2A 2297/4885
US-20090030202-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT AND ORGANIC ELECTROLUMINESCENT ELEMENT EMPLOYING THE SAME EMC2, L1CAM, EMC1 MAPT 150/4885NPC1 3452/4885PLA2G2A 2297/4885
US-20090017331-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE UTILIZING THE SAME ICMT, ORAI2, ILK MAPT 234/4885NPC1 818/4885PLA2G2A 3252/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.