SCHEMBL805054

SCHEMBL805054

C=CC(=O)OCc1cc(C(F)(F)F)cc(C(F)(F)F)c1

nearest known ligand 0.49

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.49
PRKCA P17252 1/20 0.40
PRKCD Q05655 1/20 0.40
MTOR P42345 1/20 0.40
CES2 O00748 1/20 0.40
TGM2 P21980 2/20 0.39
ALDH1A1 P00352 1/20 0.39
MMP1 P03956 1/20 0.38
MMP12 P39900 1/20 0.38
TACR1 P25103 8/20 0.38
MRGPRX4 Q96LA9 1/20 0.37
LMNA P02545 1/20 0.37
RXRA P19793 1/20 0.37
RXRB P28702 1/20 0.37
RXRG P48443 1/20 0.37
CACNA1F O60840 2/20 0.37
CACNA1D Q01668 2/20 0.37
CACNA1S Q13698 2/20 0.37
CACNA1C Q13936 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL798798 0.90 MRGPRX4 (0.41) IDO1PRKCAPRKCDTGM2ALDH1A1
SCHEMBL2036674 0.84 PRKCA (0.59) IDO1PRKCAPRKCDTGM2ALDH1A1
SCHEMBL10659178 0.83 MMP12 (0.49) IDO1TGM2ALDH1A1MMP1MMP12
SCHEMBL21913948 0.82 TSHR (0.46) TGM2ALDH1A1LMNA
SCHEMBL4873024 0.77 IDO1 (0.58) IDO1PRKCAPRKCDMTORCES2
SCHEMBL8838337 0.77 IDO1 (0.53) IDO1PRKCAPRKCDMTORCES2
SCHEMBL15339015 0.77 TSHR (0.42) TGM2ALDH1A1LMNA
SCHEMBL13292600 0.75 IDO1 (0.47) IDO1PRKCAPRKCDMTORCES2
SCHEMBL29064876 0.75 CES2 (0.45) CES2TGM2LMNARXRARXRB
SCHEMBL27255656 0.75 IDO1 (0.50) IDO1PRKCAPRKCDMTORCES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8318656-B2 Production processes and systems, compositions, surfactants, monomer units, metal complexes, phosphate esters, glycols, aqueous film forming foams, and foam stabilizers E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-11-27 US disclosed
US-20120071689-A1 PRODUCTION PROCESSES AND SYSTEMS, COMPOSITIONS, SURFACTANTS, MONOMER UNITS, METAL COMPLEXES, PHOSPHATE ESTERS, GLYCOLS, AQUEOUS FILM FORMING FOAMS, AND FOAM STABILIZERS E.I. DU PONT DE NEMOURS AND COMPANY CHEMTURA CORPORATION (US) 2012-03-22 US disclosed
US-7943567-B2 Production processes and systems, compositions, surfactants, monomer units, metal complexes, phosphate esters, glycols, aqueous film forming foams, and foam stabilizers E.I. DU PONT DE NEMOURS AND COMPANY (US) 2011-05-17 US disclosed
US-7943567-B2 Production processes and systems, compositions, surfactants, monomer units, metal complexes, phosphate esters, glycols, aqueous film forming foams, and foam stabilizers E.I. DU PONT DE NEMOURS AND COMPANY (US) 2011-05-17 US disclosed
US-20080076892-A1 Telomer compositions and production processes E. I. DU PONT DE NEMOURS AND COMPANY 2008-03-27 US disclosed
US-20080076892-A1 Telomer compositions and production processes E. I. DU PONT DE NEMOURS AND COMPANY 2008-03-27 US disclosed
WO-2008019111-A2 TELOMER COMPOSITIONS AND PRODUCTION PROCESSES GREAT LAKES CHEMICAL CORPORATION (US) 2008-02-14 WO disclosed
US-20080009655-A1 Production Processes and Systems, Compositions, Surfactants, Monomer Units, Metal Complexes, Phosphate Esters, Glycols, Aqueous Film Forming Foams, and Foam Stabilizers E. I. DU PONT DE NEMOURS AND COMPANY 2008-01-10 US disclosed
US-20080009655-A1 Production Processes and Systems, Compositions, Surfactants, Monomer Units, Metal Complexes, Phosphate Esters, Glycols, Aqueous Film Forming Foams, and Foam Stabilizers E. I. DU PONT DE NEMOURS AND COMPANY 2008-01-10 US disclosed
US-20070282115-A1 Production Processes and Systems, Compositions, Surfactants, Monomer Units, Metal Complexes, Phosphate Esters, Glycols, Aqueous Film Foams, and Foam Stabilizers E. I. DU PONT DE NEMOURS AND COMPANY 2007-12-06 US disclosed
US-20070282115-A1 Production Processes and Systems, Compositions, Surfactants, Monomer Units, Metal Complexes, Phosphate Esters, Glycols, Aqueous Film Foams, and Foam Stabilizers E. I. DU PONT DE NEMOURS AND COMPANY 2007-12-06 US disclosed
US-20070161537-A1 Production processes and systems, compositions, surfactants, monomer units, metal complexes, phosphate esters, glycols, aqueous film forming foams and foam stabilizers GREAT LAKES CHEMICAL CORPORATION (US) 2007-07-12 US disclosed
US-20070161537-A1 Production processes and systems, compositions, surfactants, monomer units, metal complexes, phosphate esters, glycols, aqueous film forming foams and foam stabilizers GREAT LAKES CHEMICAL CORPORATION (US) 2007-07-12 US disclosed
US-20070149437-A1 Production processes and systems, compositions, surfactants, monomer units, metal complexes, phosphate esters, glycols, aqueous film forming foams, and foams stabilizers E. I. DU PONT DE NEMOURS AND COMPANY 2007-06-28 US disclosed
US-20070149437-A1 Production processes and systems, compositions, surfactants, monomer units, metal complexes, phosphate esters, glycols, aqueous film forming foams, and foams stabilizers E. I. DU PONT DE NEMOURS AND COMPANY 2007-06-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080009655-A1 Production Processes and Systems, Compositions, Surfactants, Monomer Units, Metal Complexes, Phosphate Esters, Glycols, Aqueous Film Forming Foams, and Foam Stabilizers FOS, AFF4, AFF1 IDO1 4850/4885PRKCA 2140/4885PRKCD 1950/4885
US-20120071689-A1 PRODUCTION PROCESSES AND SYSTEMS, COMPOSITIONS, SURFACTANTS, MONOMER UNITS, METAL COMPLEXES, PHOSPHATE ESTERS, GLYCOLS, AQUEOUS FILM FORMING FOAMS, AND FOAM STABILIZERS FOS, AFF4, AFF1 IDO1 4859/4885PRKCA 2186/4885PRKCD 2001/4885
US-20070282115-A1 Production Processes and Systems, Compositions, Surfactants, Monomer Units, Metal Complexes, Phosphate Esters, Glycols, Aqueous Film Foams, and Foam Stabilizers FOS, AFF4, AFF1 IDO1 4849/4885PRKCA 2603/4885PRKCD 2091/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.