Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | XPO1 | O14980 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.34 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.33 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.33 |
| ▸ | ITGAL | P20701 | 2/20 | 0.33 |
| ▸ | EIF4E | P06730 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 2/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 2/20 | 0.32 |
| ▸ | HTR7 | P34969 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8050993 | 0.93 | CTSS (0.36) | F2RL3CTSSCTSKARMAPT | |
| SCHEMBL8050186 | 0.91 | ATP4A (0.35) | F2RL3CTSSCTSKARMAPT | |
| SCHEMBL8032747 | 0.86 | F2RL3 (0.37) | F2RL3CTSSCTSKARMAPT | |
| SCHEMBL8045305 | 0.86 | F2RL3 (0.35) | F2RL3ARMAPTXPO1ALOX5 | |
| SCHEMBL8048213 | 0.85 | XPO1 (0.40) | F2RL3MAPTXPO1ITGB2ICAM1 | |
| SCHEMBL8033766 | 0.84 | F2RL3 (0.36) | F2RL3CTSSCTSKARMAPT | |
| SCHEMBL8033189 | 0.84 | RAB9A (0.38) | ARALOX5EIF4ELTA4HHTR1A | |
| SCHEMBL8045490 | 0.83 | EIF4E (0.36) | ARMAPTEIF4ELTA4HHTR1A | |
| SCHEMBL8032734 | 0.80 | ALDH1A1 (0.37) | F2RL3CTSSCTSKARMAPT | |
| SCHEMBL8051868 | 0.78 | HTR1A (0.52) | ARMAPTHTR1AHTR7HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |