Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 14/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8051066 | 0.81 | RAB9A (0.44) | ALDH1A1SMN1; SMN2HPGDALOX15HSD17B10 | |
| SCHEMBL8050828 | 0.80 | ALDH1A1 (0.48) | ALDH1A1TSHRSMN1; SMN2KDM4EHPGD | |
| SCHEMBL8043960 | 0.78 | L3MBTL1 (0.51) | ALDH1A1TSHRSMN1; SMN2L3MBTL1KDM4E | |
| SCHEMBL8042762 | 0.78 | NPC1 (0.41) | ALDH1A1TSHRSMN1; SMN2HPGDALOX15 | |
| SCHEMBL8034295 | 0.78 | NPC1 (0.42) | ALDH1A1SMN1; SMN2L3MBTL1RAB9ANPC1 | |
| SCHEMBL8032463 | 0.78 | POLB (0.41) | ALDH1A1TSHRSMN1; SMN2KDM4EHPGD | |
| SCHEMBL8048297 | 0.78 | HDAC6 (0.45) | ALDH1A1SMN1; SMN2HPGDALOX15HSD17B10 | |
| SCHEMBL8046654 | 0.78 | TSHR (0.42) | ALDH1A1TSHRL3MBTL1KDM4EHPGD | |
| SCHEMBL8032670 | 0.77 | ALDH1A1 (0.51) | ALDH1A1TSHRSMN1; SMN2KDM4EHPGD | |
| SCHEMBL8051515 | 0.77 | HPGD (0.49) | ALDH1A1TSHRSMN1; SMN2HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |