SCHEMBL805208

SCHEMBL805208

CN[C@@H](Cc1ccc(Cl)cc1)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.51
PPARG P37231 7/20 0.50
PPARA Q07869 4/20 0.50
ADAMTS5 Q9UNA0 1/20 0.50
MMP2 P08253 1/20 0.50
KMT2A Q03164 1/20 0.49
LMNA P02545 2/20 0.49
ALDH1A1 P00352 1/20 0.49
GRN P28799 1/20 0.47
SORT1 Q99523 1/20 0.47
EPHX2 P34913 1/20 0.47
GPR34 Q9UPC5 1/20 0.45
ACACB O00763 1/20 0.44
MME P08473 1/20 0.44
ACE P12821 1/20 0.44
CPA1 P15085 1/20 0.44
ACE2 Q9BYF1 1/20 0.44
FOLH1 Q04609 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2033051 1.00 CA2 (0.51) CA2PPARGPPARAADAMTS5MMP2
SCHEMBL4303242 1.00 CA2 (0.51) CA2PPARGPPARAADAMTS5MMP2
Hydrochloric Acid SCHEMBL7310351 0.98 CA2 (0.50) CA2PPARGPPARAADAMTS5MMP2
Hydrochloric Acid SCHEMBL7310346 0.98 CA2 (0.50) CA2PPARGPPARAADAMTS5MMP2
SCHEMBL12379271 0.91 PPARG (0.57) PPARGPPARAKMT2AGPR34MME
SCHEMBL12188588 0.86 ACACB (0.48) CA2PPARGPPARAADAMTS5MMP2
SCHEMBL14950914 0.86 ACACB (0.48) CA2PPARGPPARAADAMTS5MMP2
SCHEMBL13323474 0.86 ACACB (0.48) CA2PPARGPPARAADAMTS5MMP2
SCHEMBL27699871 0.85 CA2 (0.54) CA2PPARGPPARAADAMTS5MMP2
SCHEMBL5022525 0.85 CA2 (0.54) CA2PPARGPPARAADAMTS5MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025100520-A1 PEPTIDE, PEPTIDE COMPLEX, PHARMACEUTICAL COMPOSITION, COMPOSITION FOR CELL CULTURE, AND COMPOSITION FOR MEDICAL USE, DIAGNOSTIC USE, OR RESEARCH USE ペプチドリーム株式会社 2025-05-15 WO claimed
US-11279732-B2 Somatostatin receptor antagonist compounds and methods of using the same CDRD VENTURES INC. (CA) 2022-03-22 US claimed
US-12637494-B2 Method for producing peptide containing non-natural amino acid CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2026-05-26 US disclosed
US-20260098061-A1 EPHA2-BINDING PENDING PEPTIDE AND COMPOSITION COMPRISING SAME PEPTIDREAM INC (JP) 2026-04-09 US disclosed
EP-4667483-A1 HUMAN TRANSFERRIN RECEPTOR-BINDING PEPTIDE JCR Pharmaceuticals Co., Ltd. (JP) 2025-12-24 EP disclosed
US-12486302-B2 Somatostatin receptor antagonist compounds and methods of using the same CDRD VENTURES INC. (CA) 2025-12-02 US disclosed
US-20250361274-A1 PEPTIDE AND PEPTIDE-CONTAINING AGENT PEPTIDREAM INC. (JP) 2025-11-27 US disclosed
US-20250340916-A1 METHOD FOR SYNTHESIZING PEPTIDES IN CELL-FREE TRANSLATION SYSTEM CHUGAI PHARMACEUTICAL CO LTD (JP) 2025-11-06 US disclosed
EP-4628592-A1 PEPTIDE PRODUCTION METHOD COMPRISING STEP FOR TRANSLATING AMINO ACID HAVING OXYGEN ATOM AT SPECIFIC POSITION CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-10-08 EP disclosed
US-12415835-B2 Peptide-compound cyclization method CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-09-16 US disclosed
EP-4603105-A1 PHARMACEUTICAL COMPOSITION CONTAINING CYCLIC COMPOUND HAVING SELECTIVE KRAS INHIBITORY EFFECT AGAINST HRAS AND NRAS CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-08-20 EP disclosed
EP-2061886-A1 SMALL CATIONIC ANTIMICROBIAL PEPTIDES The University of British Columbia (CA) 2009-05-27 EP disclosed
WO-2008022444-A1 SMALL CATIONIC ANTIMICROBIAL PEPTIDES THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2008-02-28 WO disclosed
US-5763404-A LUTEINIZING HORMONE RELEASING HORMONE UNIV TEXAS (US) 1998-06-09 US disclosed
EP-0797567-A1 NOVEL AMINO ACID DERIVATIVES WITH IMPROVED MULTI-DRUG RESISTANCE ACTIVITY Vertex Pharmaceuticals Incorporated (US) 1997-10-01 EP disclosed
WO-1996015101-A1 NOVEL AMINO ACID DERIVATIVES WITH IMPROVED MULTI-DRUG RESISTANCE ACTIVITY VERTEX PHARMACEUTICALS INCORPORATED (US) 1996-05-23 WO disclosed
US-5470947-A Lutenizing hormone-releasing hormone, contraceptives BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1995-11-28 US disclosed
EP-0377665-B1 EFFECTIVE ANTAGONISTS OF THE LUTEINIZING HORMONE RELEASING HORMONE WHICH RELEASE NEGLIGIBLE HISTAMINE UNIV TEXAS (US) 1995-07-12 EP disclosed
EP-0377665-A1 EFFECTIVE ANTAGONISTS OF THE LUTEINIZING HORMONE RELEASING HORMONE WHICH RELEASE NEGLIGIBLE HISTAMINE. UNIV TEXAS (US) 1990-07-18 EP disclosed
WO-1989001944-A1 EFFECTIVE ANTAGONISTS OF THE LUTEINIZING HORMONE RELEASING HORMONE WHICH RELEASE NEGLIGIBLE HISTAMINE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1989-03-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12637494-B2 Method for producing peptide containing non-natural amino acid MRPL21, RPL21, RPL30 CA2 4790/4885PPARG 4419/4885PPARA 4075/4885
US-12486302-B2 Somatostatin receptor antagonist compounds and methods of using the same GPR119, SSTR5, SSTR2 CA2 326/4885PPARG 729/4885PPARA 798/4885
US-11279732-B2 Somatostatin receptor antagonist compounds and methods of using the same GPR119, SSTR5, SSTR2 CA2 322/4885PPARG 752/4885PPARA 822/4885
US-20250361274-A1 PEPTIDE AND PEPTIDE-CONTAINING AGENT BMP4, BMP1, BMPR2 CA2 1755/4885PPARG 2415/4885PPARA 2375/4885
US-20260098061-A1 EPHA2-BINDING PENDING PEPTIDE AND COMPOSITION COMPRISING SAME EPHA2, EPHA1, EPHB1 CA2 3688/4885PPARG 3511/4885PPARA 2619/4885
US-20250340916-A1 METHOD FOR SYNTHESIZING PEPTIDES IN CELL-FREE TRANSLATION SYSTEM AARS1, NSUN3, RNGTT CA2 4555/4885PPARG 4481/4885PPARA 3764/4885
US-12415835-B2 Peptide-compound cyclization method VIP, NGLY1, GLP1R CA2 2242/4885PPARG 3973/4885PPARA 3215/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.