Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 4/20 | 0.50 |
| ▸ | GNAI1 | P63096 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10663507 | 0.91 | L3MBTL1 (0.58) | GNAI3GNAI1TDP1GNAO1L3MBTL1 | |
| SCHEMBL674671 | 0.91 | — | — | |
| SCHEMBL11240 | 0.87 | L3MBTL1 (0.62) | GNAI3GNAI1TDP1GNAO1L3MBTL1 | |
| SCHEMBL4548026 | 0.85 | L3MBTL1 (0.71) | GNAI3GNAI1TDP1GNAO1L3MBTL1 | |
| SCHEMBL13779924 | 0.84 | HTT (0.54) | GNAI3GNAI1GNAO1L3MBTL1KMT2A | |
| SCHEMBL8972071 | 0.84 | GNAI3 (0.71) | GNAI3GNAI1TDP1GNAO1L3MBTL1 | |
| SCHEMBL8972364 | 0.84 | GNAI3 (0.71) | GNAI3GNAI1TDP1GNAO1L3MBTL1 | |
| SCHEMBL31632756 | 0.84 | GNAI3 (0.71) | GNAI3GNAI1TDP1GNAO1L3MBTL1 | |
| SCHEMBL8972105 | 0.84 | GNAI3 (0.71) | GNAI3GNAI1TDP1GNAO1L3MBTL1 | |
| SCHEMBL8972852 | 0.84 | GNAI3 (0.71) | GNAI3GNAI1TDP1GNAO1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 122 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116375715-B | Compound serving as non-covalent BTK kinase inhibitor and biological application thereof | 中国药科大学 | 2025-04-04 | — | — | CN | disclosed |
| EP-3816164-B9 | ISOTHIAZOLO[5,4-D]PYRIMIDINE COMPOUND AS IRAK4 INHIBITOR | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO LTD (CN) | 2024-07-10 | — | — | EP | disclosed |
| WO-2024026260-A1 | SUBSTITUTED IMIDAZOPYRAZINE COMPOUNDS AS IRAK3 BINDERS | CELGENE CORPORATION (US) | 2024-02-01 | — | — | WO | disclosed |
| US-11725007-B2 | Meta tyrosine derivatives as rho-kinase inhibitors | CHIESI FARMACEUTICI S.P.A. (IT) | 2023-08-15 | — | — | US | disclosed |
| CN-116375715-A | Compound serving as non-covalent BTK kinase inhibitor and biological application thereof | 中国药科大学 | 2023-07-04 | — | — | CN | disclosed |
| CN-113195510-B | Process for producing glucopyranosyl derivative and intermediate therefor | 宜昌东阳光长江药业股份有限公司 | 2022-12-23 | — | — | CN | disclosed |
| EP-4013508-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | Bayer Aktiengesellschaft (DE) | 2022-06-22 | — | — | EP | disclosed |
| EP-3728235-B1 | SUBSTITUTED THIOPHENYLURACILS , THEIR SALTS AND USE OF SAID COMPOUNDS AS HERBICIDAL AGENTS | SYNGENTA CROP PROTECTION AG (CH) | 2022-02-09 | — | — | EP | disclosed |
| EP-3831841-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T Global Inc. (US) | 2021-06-09 | — | — | EP | disclosed |
| EP-3778571-A1 | (2E,4E)-5-PHENYL-PENTA-2,4-DIEN-1-ONE DERIVATIVE | Bioway, Inc. (KR) | 2021-02-17 | — | — | EP | disclosed |
| US-20080139559-A1 | DIARYLAMINE-CONTAINING COMPOUNDS AND COMPOSITIONS, AND THEIR USE AS MODULATORS OF C-KIT RECEPTORS | IRM LLC, A DELAWARE LIMITED LIABILITY COMAPNY (BM) | 2008-06-12 | — | — | US | disclosed |
| US-20080139597-A1 | DIARYLAMINE-CONTAINING COMPOUNDS AND COMPOSITIONS, AND THEIR USE AS MODULATORS OF C-KIT RECEPTORS | IRM LLC, A DELAWARE LIMITED LIABILITY COMAPNY (BM) | 2008-06-12 | — | — | US | disclosed |
| US-20080139560-A1 | Ion Channel Modulators | SCION PHARMACEUTICALS, INC. | 2008-06-12 | — | — | US | disclosed |
| US-20070191469-A1 | Novel tetracyclic tetrahydrofuran derivatives | JANSSEN-CILAG S.A. (ES) | 2007-08-16 | — | — | US | disclosed |
| US-20070191469-A1 | Novel tetracyclic tetrahydrofuran derivatives | JANSSEN-CILAG S.A. (ES) | 2007-08-16 | — | — | US | disclosed |
| US-20070149538-A1 | Diarylamine-Containing Compounds and Compositions, and their use as Modulators of C-Kit Receptors | IRM LLC (BM) | 2007-06-28 | — | — | US | disclosed |
| EP-1740574-B1 | 4-AMINO-5-CYANOPYRIMIDINE DERIVATIVES | OTSUKA PHARMA CO LTD (JP) | 2007-06-27 | — | — | EP | disclosed |
| WO-2007019674-A1 | VIRAL POLYMERASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-02-22 | — | — | WO | disclosed |
| WO-2005097112-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2005-10-20 | — | — | WO | disclosed |
| US-20050070550-A1 | Benzoimidazole compounds | JANSSEN PHARMACEUTICA, N.V. (BE) | 2005-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050070550-A1 | Benzoimidazole compounds | HRH4, HRH3, BRD4 | GNAI3 771/4885GNAI1 1063/4885TDP1 4637/4885 |
| US-20080139560-A1 | Ion Channel Modulators | CACNA1B, CACNA1C, TRPV1 | GNAI3 724/4885GNAI1 673/4885TDP1 3756/4885 |
| US-20070191469-A1 | Novel tetracyclic tetrahydrofuran derivatives | HTR2C, HTR2A, HTR1A | GNAI3 464/4885GNAI1 203/4885TDP1 2025/4885 |
| US-20080139597-A1 | DIARYLAMINE-CONTAINING COMPOUNDS AND COMPOSITIONS, AND THEIR USE AS MODULATORS OF C-KIT RECEPTORS | KIT, PRKCH, PRKCE | GNAI3 492/4885GNAI1 408/4885TDP1 2495/4885 |
| US-11725007-B2 | Meta tyrosine derivatives as rho-kinase inhibitors | ROCK1, ROCK2, RHOA | GNAI3 343/4885GNAI1 274/4885TDP1 1103/4885 |
| US-20070149538-A1 | Diarylamine-Containing Compounds and Compositions, and their use as Modulators of C-Kit Receptors | KIT, PRKCH, PRKCE | GNAI3 492/4885GNAI1 408/4885TDP1 2495/4885 |
| US-20080139559-A1 | DIARYLAMINE-CONTAINING COMPOUNDS AND COMPOSITIONS, AND THEIR USE AS MODULATORS OF C-KIT RECEPTORS | KIT, PRKCH, PRKCE | GNAI3 492/4885GNAI1 408/4885TDP1 2495/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.