Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | HTR2B | P41595 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.56 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.56 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.56 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | DRD2 | P14416 | 1/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | DRD3 | P35462 | 1/20 | 0.56 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9527372 | 0.75 | HTR2C (0.46) | MAPTHTR2BLMNAADRB1DRD2 | |
| SCHEMBL5915126 | 0.74 | DRD2 (0.51) | MAPTHTR2BLMNAADRB1HTR1A | |
| SCHEMBL28975143 | 0.72 | MAPT (0.63) | HRH1TSHRADRA1AMAPTHTR2B | |
| Urapidil SCHEMBL48992 | 0.72 | HTR1A (1.00) | HRH1TSHRADRA1AMAPTHTR2B | |
| Urapidil SCHEMBL29363219 | 0.72 | HTR1A (1.00) | HRH1TSHRADRA1AMAPTHTR2B | |
| SCHEMBL8017476 | 0.72 | HTR2C (0.41) | TSHRADRA1AHTR2BADRB1HTR1A | |
| Urapidil SCHEMBL1321654 | 0.71 | MAPT (1.00) | HRH1TSHRADRA1AMAPTHTR2B | |
| Urapidil SCHEMBL30426045 | 0.71 | MAPT (1.00) | HRH1TSHRADRA1AMAPTHTR2B | |
| SCHEMBL9132291 | 0.71 | ADRA1A (0.64) | HRH1TSHRADRA1AMAPTHTR2B | |
| SCHEMBL10924750 | 0.70 | SIGMAR1 (0.47) | ADRA1ADRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6046329-A | Uracil derivatives | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 2000-04-04 | — | — | US | disclosed |