Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNOT7 | Q9UIV1 | 3/20 | 0.47 |
| ▸ | PARN | O95453 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PNP | P00491 | 2/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.39 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974492 | 0.88 | ABCC8 (0.47) | CNOT7PARNSMN1; SMN2ADORA2BRXFP1 | |
| SCHEMBL7985328 | 0.87 | CNOT7 (0.51) | CNOT7PARNSMN1; SMN2ADORA2BRXFP1 | |
| SCHEMBL7986239 | 0.87 | CNOT7 (0.47) | CNOT7PARNSMN1; SMN2ADORA2BRXFP1 | |
| SCHEMBL7975271 | 0.85 | CNOT7 (0.56) | CNOT7PARNSMN1; SMN2ADORA2BRXFP1 | |
| SCHEMBL7988790 | 0.84 | CNOT7 (0.53) | CNOT7PARNSMN1; SMN2ADORA2BRXFP1 | |
| SCHEMBL7984975 | 0.83 | CXCR2 (0.53) | CNOT7PARNSMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL8056958 | 0.83 | SMN1; SMN2 (0.52) | CNOT7PARNSMN1; SMN2ADORA2BRXFP1 | |
| SCHEMBL7984891 | 0.83 | CNOT7 (0.50) | CNOT7PARNSMN1; SMN2ADORA2BRXFP1 | |
| SCHEMBL7985350 | 0.83 | GAA (0.48) | CNOT7PARNRXFP1HPGDP2RX7 | |
| SCHEMBL7988685 | 0.83 | PARN (0.41) | CNOT7PARNSMN1; SMN2HPGDPNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |