Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 1/20 | 0.40 |
| ▸ | GABRD | O14764 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.40 |
| ▸ | GABRE | P78334 | 1/20 | 0.40 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.40 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.40 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.40 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 2/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8058876 | 1.00 | GABRP (0.40) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8064336 | 0.81 | CYP11B2 (0.40) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL9207794 | 0.78 | MAPK1 (0.44) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8047202 | 0.76 | NPBWR1 (0.48) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL27461045 | 0.76 | LMNA (0.42) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL9210384 | 0.74 | CYP11B2 (0.45) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8059782 | 0.74 | GABRB3 (0.46) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8062271 | 0.73 | CYP11B2 (0.40) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8433371 | 0.73 | GABRB3 (0.41) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8057793 | 0.73 | CYP11B2 (0.40) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0630367-B1 | NOVEL ARYLINDAZOLES AND THEIR USE AS HERBICIDES | ZENECA LTD (GB) | 2000-07-05 | — | — | EP | disclosed |
| US-5444038-A | Arylindazoles and their use as herbicides | ZENECA LIMITED (GB) | 1995-08-22 | — | — | US | disclosed |
| WO-1993018008-A1 | NOVEL ARYLINDAZOLES AND THEIR USE AS HERBICIDES | ZENECA LIMITED (GB) | 1993-09-16 | — | — | WO | disclosed |