SCHEMBL8066258

SCHEMBL8066258

CCCN(Oc1ccccc1)C(F)(F)F

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 4/20 0.35
TSHR P16473 1/20 0.34
HSD17B10 Q99714 1/20 0.34
SLC6A4 P31645 1/20 0.34
HRH3 Q9Y5N1 1/20 0.34
FDPS P14324 1/20 0.34
MAPT P10636 2/20 0.33
BCHE P06276 2/20 0.33
HTT P42858 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
LMNA P02545 3/20 0.33
CYP2D6 P10635 1/20 0.33
ALOX12 P18054 1/20 0.33
RECQL P46063 1/20 0.33
CA4 P22748 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9793552 0.75 TSHR (0.40) LTA4HTSHRHSD17B10FDPSMAPT
SCHEMBL27882736 0.74 LTA4H (0.41) LTA4HTSHRHSD17B10BCHEL3MBTL1
SCHEMBL27404289 0.72 LTA4H (0.40) LTA4HTSHRHSD17B10SLC6A4MAPT
SCHEMBL7574406 0.72 CHRNB2 (0.44) TSHRL3MBTL1LMNACYP2D6
SCHEMBL27918079 0.71 LTA4H (0.38) LTA4HTSHRHSD17B10BCHEL3MBTL1
SCHEMBL10654697 0.70 L3MBTL1 (0.37) LTA4HTSHRHSD17B10FDPSMAPT
SCHEMBL9029307 0.70 LTA4H (0.40) LTA4HSLC6A4HRH3FDPSMAPT
SCHEMBL1045799 0.69 TP53 (0.38) LTA4HTSHRHSD17B10BCHEL3MBTL1
SCHEMBL26654541 0.68 SLC6A9 (0.35) FDPSMAPTLMNA
SCHEMBL11504408 0.68 LTA4H (0.38) LTA4HTSHRHSD17B10FDPSBCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1003717-A1 PREPARATION AND USES OF HYDROCARBYLNITRONES ALBEMARLE CORPORATION (US) 2000-05-31 EP disclosed
WO-1999006362-A1 PREPARATION AND USES OF HYDROCARBYLNITRONES ALBEMARLE CORPORATION (US) 1999-02-11 WO disclosed