Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8079570 | 0.92 | TP53 (0.34) | TP53SMN1; SMN2LMNAGAAMAPT | |
| SCHEMBL8470367 | 0.89 | PTGES (0.35) | TP53SMN1; SMN2PTGESALOX5LMNA | |
| SCHEMBL8066369 | 0.89 | TP53 (0.33) | TP53SMN1; SMN2LMNAMAPTKMT2A | |
| SCHEMBL8470961 | 0.81 | ALDH1A1 (0.33) | TP53SMN1; SMN2LMNAGAAMAPT | |
| Bromide SCHEMBL8076253 | 0.81 | ALDH1A1 (0.42) | TP53SMN1; SMN2PTGESALOX5LMNA | |
| Bromide SCHEMBL8076530 | 0.79 | KEAP1 (0.46) | TP53PTGESALOX5LMNAGAA | |
| SCHEMBL8471242 | 0.79 | ALDH1A1 (0.33) | TP53SMN1; SMN2LMNAGAAMAPT | |
| Bromide SCHEMBL8066341 | 0.77 | ALDH1A1 (0.46) | TP53SMN1; SMN2PTGESALOX5LMNA | |
| Bromide SCHEMBL8076287 | 0.74 | KEAP1 (0.43) | TP53LMNAGAAMAPTKMT2A | |
| SCHEMBL9407911 | 0.72 | LMNA (0.49) | TP53SMN1; SMN2LMNAGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0330050-B1 | Special chemiluminescent acridine derivatives and their use in luminescence immunoassays | DADE BEHRING MARBURG GMBH (DE) | 2000-08-23 | — | — | EP | disclosed |
| EP-0330050-A2 | Special chemiluminescent acridine derivatives and their use in luminescence immunoassays | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-08-30 | — | — | EP | disclosed |