Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 5/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | TP53 | P04637 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8470961 | 0.91 | ALDH1A1 (0.33) | LMNAGAAKEAP1NFE2L2MAPT | |
| SCHEMBL8066320 | 0.89 | TP53 (0.36) | PTGESALOX5LMNAGAAKEAP1 | |
| SCHEMBL8471242 | 0.89 | ALDH1A1 (0.33) | LMNAGAAMAPTTP53KMT2A | |
| SCHEMBL8079570 | 0.81 | TP53 (0.34) | LMNAGAAMAPTTP53KMT2A | |
| SCHEMBL8066369 | 0.79 | TP53 (0.33) | LMNAMAPTTP53KMT2APOLB | |
| SCHEMBL8470369 | 0.79 | LMNA (0.41) | PTGESALOX5LMNAGAAKEAP1 | |
| Bromide SCHEMBL8469899 | 0.79 | KEAP1 (0.45) | PTGESALOX5LMNAKEAP1NFE2L2 | |
| Bromide SCHEMBL8471510 | 0.78 | HSP90AA1 (0.50) | PTGESALOX5LMNAGAAKEAP1 | |
| Bromide SCHEMBL8469737 | 0.76 | ALDH1A1 (0.50) | PTGESALOX5LMNAGAAKEAP1 | |
| SCHEMBL13433217 | 0.74 | KMT2A (0.51) | LMNAGAAKEAP1NFE2L2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6002007-A | Special chemiluminescent acridine derivatives and the use thereof in luminescence immunoassays | DADE BEHRING MARBURG GMBH (DE) | 1999-12-14 | — | — | US | disclosed |