Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | RAD52 | P43351 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8066320 | 0.92 | TP53 (0.36) | TP53SMN1; SMN2ALDH1A1NPSR1LMNA | |
| SCHEMBL8470961 | 0.90 | ALDH1A1 (0.33) | TP53SMN1; SMN2ALDH1A1NPSR1LMNA | |
| SCHEMBL8066369 | 0.88 | TP53 (0.33) | TP53SMN1; SMN2ALDH1A1NPSR1LMNA | |
| SCHEMBL8066354 | 0.81 | SMN1; SMN2 (0.37) | TP53SMN1; SMN2ALDH1A1NPSR1LMNA | |
| SCHEMBL8470367 | 0.81 | PTGES (0.35) | TP53SMN1; SMN2ALDH1A1NPSR1LMNA | |
| SCHEMBL8471242 | 0.78 | ALDH1A1 (0.33) | TP53SMN1; SMN2ALDH1A1NPSR1LMNA | |
| Bromide SCHEMBL8076253 | 0.72 | ALDH1A1 (0.42) | TP53SMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL9407911 | 0.72 | LMNA (0.49) | TP53SMN1; SMN2ALDH1A1LMNAPOLB | |
| SCHEMBL8469450 | 0.71 | ALDH1A1 (0.37) | SMN1; SMN2ALDH1A1NPSR1LMNAPOLB | |
| Bromide SCHEMBL8076530 | 0.71 | KEAP1 (0.46) | TP53ALDH1A1LMNAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0330050-B1 | Special chemiluminescent acridine derivatives and their use in luminescence immunoassays | DADE BEHRING MARBURG GMBH (DE) | 2000-08-23 | — | — | EP | disclosed |
| EP-0602524-A1 | Chemiluminescence marked sequences and their use in sequence testing | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-06-22 | — | — | EP | disclosed |
| EP-0330050-A2 | Special chemiluminescent acridine derivatives and their use in luminescence immunoassays | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-08-30 | — | — | EP | disclosed |