Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SPR | P35270 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8068924 | 0.85 | PARP1 (0.38) | MAPK1ALDH1A1HSD17B10USP2LMNA | |
| SCHEMBL8069019 | 0.82 | PRMT5 (0.39) | ALDH1A1KDM4EHSD17B10GAAHPGD | |
| SCHEMBL8073368 | 0.78 | ALDH1A1 (0.43) | MAPK1ALDH1A1KDM4EHSD17B10GAA | |
| SCHEMBL7822908 | 0.78 | KDM4E (0.38) | ALDH1A1KDM4EHSD17B10NPC1RAB9A | |
| SCHEMBL7831864 | 0.75 | KDM4E (0.40) | ALDH1A1KDM4EHSD17B10GAAHPGD | |
| SCHEMBL7826505 | 0.73 | PTGES (0.47) | ALDH1A1HSD17B10HPGDCYP2C9 | |
| SCHEMBL8073330 | 0.72 | HPGD (0.50) | ALDH1A1KDM4EHSD17B10GAARAB9A | |
| SCHEMBL8057842 | 0.72 | KDM4E (0.35) | ALDH1A1KDM4EHSD17B10GAAMAPT | |
| SCHEMBL7825628 | 0.71 | PTGES (0.46) | ALDH1A1KDM4ENPC1RAB9ACYP2C9 | |
| SCHEMBL8069100 | 0.70 | NPY5R (0.35) | ROCK2GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6093714-A | AN ANTIALLERGENS FOR TREATMENT AND PREVENTION OF BRONCHIAL ASTHMA, ECZEMA, HIVES, ALLERGIC GASTROINTESTINAL TROUBLES, ALLERGIC RHINITIS, ALLERGIC CONJUNCTIVITIS | MEIJI SEIKA KAISHA, LTD. (JP) | 2000-07-25 | — | — | US | disclosed |
| EP-0834512-A1 | TRICYCLIC BENZAZEPINE COMPOUNDS | MEIJI SEIKA KAISHA LTD. (JP) | 1998-04-08 | — | — | EP | disclosed |