Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 2/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 5/20 | 0.33 |
| ▸ | PARP1 | P09874 | 2/20 | 0.33 |
| ▸ | TNK2 | Q07912 | 2/20 | 0.33 |
| ▸ | TNK1 | Q13470 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.32 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.32 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8066729 | 0.82 | MAPK1 (0.47) | ENPP2KDM4EALDH1A1HSD17B10GAA | |
| SCHEMBL8069021 | 0.81 | PRMT5 (0.40) | PRMT5WDR77HDAC6ENPP2KDM4E | |
| SCHEMBL8068924 | 0.80 | PARP1 (0.38) | ALDH1A1HSD17B10PARP1PDE3BPDE3A | |
| SCHEMBL7831864 | 0.76 | KDM4E (0.40) | KDM4EALDH1A1HSD17B10GAAHPGD | |
| SCHEMBL7822908 | 0.73 | KDM4E (0.38) | KDM4EALDH1A1HSD17B10HPGDPARP1 | |
| SCHEMBL7817176 | 0.69 | PARP1 (0.55) | KDM4EALDH1A1HSD17B10GLAGAA | |
| SCHEMBL7826505 | 0.69 | PTGES (0.47) | ALDH1A1HSD17B10HPGDPARP1 | |
| SCHEMBL7825628 | 0.69 | PTGES (0.46) | KDM4EALDH1A1 | |
| SCHEMBL8073368 | 0.67 | ALDH1A1 (0.43) | KDM4EALDH1A1HSD17B10GAAHPGD | |
| SCHEMBL7815301 | 0.67 | KDM4E (0.42) | HDAC6KDM4EALDH1A1PARP1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6093714-A | AN ANTIALLERGENS FOR TREATMENT AND PREVENTION OF BRONCHIAL ASTHMA, ECZEMA, HIVES, ALLERGIC GASTROINTESTINAL TROUBLES, ALLERGIC RHINITIS, ALLERGIC CONJUNCTIVITIS | MEIJI SEIKA KAISHA, LTD. (JP) | 2000-07-25 | — | — | US | disclosed |
| EP-0834512-A1 | TRICYCLIC BENZAZEPINE COMPOUNDS | MEIJI SEIKA KAISHA LTD. (JP) | 1998-04-08 | — | — | EP | disclosed |