Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 8/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8057465 | 0.85 | ACHE (0.46) | MAOASIGMAR1 | |
| Trifluoroacetic Acid SCHEMBL8066735 | 0.79 | MAOA (0.45) | EPHX2KDM4EMAOAPDGFRBFGFR1 | |
| SCHEMBL8068897 | 0.77 | KDM4E (0.49) | KDM4EMAOASIGMAR1HRH3PARP1 | |
| SCHEMBL8067124 | 0.76 | MAOA (0.52) | KDM4EMAOAPDGFRBFGFR1KDR | |
| SCHEMBL8068112 | 0.73 | KMT2A (0.45) | KDM4E | |
| SCHEMBL8071604 | 0.71 | TRPM8 (0.46) | KDM4EMAOA | |
| Trifluoroacetic Acid SCHEMBL8067000 | 0.71 | XDH (0.44) | KDM4ESIGMAR1HRH3 | |
| SCHEMBL8073272 | 0.68 | TGFBR1 (0.35) | KDM4E | |
| SCHEMBL2865177 | 0.67 | FGFR1 (0.45) | KDM4EMAOAPDGFRBFGFR1KDR | |
| SCHEMBL8067346 | 0.67 | CYSLTR1 (0.38) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6093714-A | AN ANTIALLERGENS FOR TREATMENT AND PREVENTION OF BRONCHIAL ASTHMA, ECZEMA, HIVES, ALLERGIC GASTROINTESTINAL TROUBLES, ALLERGIC RHINITIS, ALLERGIC CONJUNCTIVITIS | MEIJI SEIKA KAISHA, LTD. (JP) | 2000-07-25 | — | — | US | disclosed |
| EP-0834512-A1 | TRICYCLIC BENZAZEPINE COMPOUNDS | MEIJI SEIKA KAISHA LTD. (JP) | 1998-04-08 | — | — | EP | disclosed |