Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | LSS | P48449 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SCN1A | P35498 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.43 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL8066735 | 0.93 | MAOA (0.45) | MAOAKDM4ESIGMAR1HRH3PARP1 | |
| SCHEMBL7827131 | 0.90 | PARP1 (0.50) | MAOASIGMAR1HRH3PARP1FGFR1 | |
| SCHEMBL8068050 | 0.90 | XDH (0.48) | MAOAKDM4ESIGMAR1HRH3PARP1 | |
| SCHEMBL7831263 | 0.86 | ACHE (0.52) | MAOAKDM4EHRH3ALDH1A1MAPK1 | |
| Trifluoroacetic Acid SCHEMBL8067000 | 0.83 | XDH (0.44) | KDM4ESIGMAR1HRH3ALDH1A1 | |
| SCHEMBL8071910 | 0.83 | ACHE (0.53) | MAOASIGMAR1HRH3SLC6A4ACHE | |
| SCHEMBL7824605 | 0.80 | CTSV (0.43) | MAOA | |
| SCHEMBL7829082 | 0.79 | CTSV (0.44) | MAOAALDH1A1HPGD | |
| SCHEMBL7826517 | 0.79 | MAOA (0.52) | MAOAKDM4EPARP1ALDH1A1CYP1A2 | |
| SCHEMBL7826175 | 0.78 | MAOA (0.54) | MAOAKDM4ESIGMAR1HRH3PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6093714-A | AN ANTIALLERGENS FOR TREATMENT AND PREVENTION OF BRONCHIAL ASTHMA, ECZEMA, HIVES, ALLERGIC GASTROINTESTINAL TROUBLES, ALLERGIC RHINITIS, ALLERGIC CONJUNCTIVITIS | MEIJI SEIKA KAISHA, LTD. (JP) | 2000-07-25 | — | — | US | disclosed |