SCHEMBL806809

SCHEMBL806809

Cc1ccc2c(C(=O)c3ccc(F)cc3)c(C)ccc2c1C(=O)c1ccc(F)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 1/20 0.47
PTGS1 P23219 1/20 0.47
PTGS2 P35354 1/20 0.47
CES2 O00748 1/20 0.46
CES1 P23141 1/20 0.46
KDM4E B2RXH2 2/20 0.46
HTT P42858 2/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
CA1 P00915 2/20 0.43
CA2 P00918 2/20 0.43
SMN1; SMN2 Q16637 5/20 0.42
LMNA P02545 4/20 0.42
ALDH1A1 P00352 4/20 0.42
TDP1 Q9NUW8 1/20 0.42
NPC1 O15118 4/20 0.41
RAB9A P51151 4/20 0.41
TP53 P04637 2/20 0.41
BCL2L1 Q07817 1/20 0.41
BAD Q92934 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL806909 0.82 HTT (0.60) HTTMEN1KMT2ACA1CA2
SCHEMBL6096428 0.82 KDM4E (0.49) LTA4HPTGS1PTGS2CES2CES1
SCHEMBL30692010 0.80 SRD5A2 (0.50) PTGS2CES2CES1HTTCA1
SCHEMBL7498185 0.78 PTGS2 (0.62) PTGS1PTGS2ESR1
SCHEMBL7499622 0.77 PTGS1 (0.48) PTGS1PTGS2KDM4ECA1CA2
SCHEMBL9726573 0.76 KMT2A (0.57) LTA4HPTGS1PTGS2CES2CES1
SCHEMBL15197082 0.76 SMN1; SMN2 (0.69) LTA4HCES2CES1KDM4EHTT
SCHEMBL27763766 0.76 PDE10A (0.51) HTTCA1CA2SMN1; SMN2LMNA
SCHEMBL238259 0.75 LTA4H (0.73) LTA4HCES2CES1KDM4EHTT
SCHEMBL8572071 0.75 LTA4H (0.73) LTA4HCES2CES1KDM4EHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2616507-B1 ORGANIC-INORGANIC COMPOSITE, MOLDED PRODUCT, AND OPTICAL ELEMENT CANON KK (JP) 2015-07-22 EP disclosed
EP-2616507-B1 ORGANIC-INORGANIC COMPOSITE, MOLDED PRODUCT, AND OPTICAL ELEMENT CANON KK (JP) 2015-07-22 EP disclosed
US-9018339-B2 Diol, and polycarbonate resin or polyester resin CANON KABUSHIKI KAISHA (JP) 2015-04-28 US disclosed
US-9018339-B2 Diol, and polycarbonate resin or polyester resin CANON KABUSHIKI KAISHA (JP) 2015-04-28 US disclosed
US-9000081-B2 Organic-inorganic composite, molded product, and optical element CANON KABUSHIKI KAISHA (JP) 2015-04-07 US disclosed
US-9000081-B2 Organic-inorganic composite, molded product, and optical element CANON KABUSHIKI KAISHA (JP) 2015-04-07 US disclosed
US-8735531-B2 Diol, and polycarbonate resin or polyester resin CANON KABUSHIKI KAISHA (JP) 2014-05-27 US disclosed
US-8735531-B2 Diol, and polycarbonate resin or polyester resin CANON KABUSHIKI KAISHA (JP) 2014-05-27 US disclosed
US-20130197182-A1 DIOL, AND POLYCARBONATE RESIN OR POLYESTER RESIN CANON KABUSHIKI KAISHA (JP) 2013-08-01 US disclosed
US-20130197182-A1 DIOL, AND POLYCARBONATE RESIN OR POLYESTER RESIN CANON KABUSHIKI KAISHA (JP) 2013-08-01 US disclosed
US-20130184391-A1 ORGANIC-INORGANIC COMPOSITE, MOLDED PRODUCT, AND OPTICAL ELEMENT CANON KABUSHIKI KAISHA (JP) 2013-07-18 US disclosed
US-20130184391-A1 ORGANIC-INORGANIC COMPOSITE, MOLDED PRODUCT, AND OPTICAL ELEMENT CANON KABUSHIKI KAISHA (JP) 2013-07-18 US disclosed
US-20130165573-A1 ORGANIC-INORGANIC COMPOSITE, MOLDED PRODUCT, AND OPTICAL ELEMENT CANON KABUSHIKI KAISHA (JP) 2013-06-27 US disclosed
US-20130165573-A1 ORGANIC-INORGANIC COMPOSITE, MOLDED PRODUCT, AND OPTICAL ELEMENT CANON KABUSHIKI KAISHA (JP) 2013-06-27 US disclosed
WO-2012036051-A1 ORGANIC-INORGANIC COMPOSITE, MOLDED PRODUCT, AND OPTICAL ELEMENT CANON KABUSHIKI KAISHA (JP) 2012-03-22 WO disclosed
WO-2012036049-A1 ORGANIC-INORGANIC COMPOSITE, MOLDED PRODUCT, AND OPTICAL ELEMENT CANON KABUSHIKI KAISHA (JP) 2012-03-22 WO disclosed
US-20110282025-A1 DIOL, AND POLYCARBONATE RESIN OR POLYESTER RESIN CANON KABUSHIKI KAISHA (JP) 2011-11-17 US disclosed
US-20110282025-A1 DIOL, AND POLYCARBONATE RESIN OR POLYESTER RESIN CANON KABUSHIKI KAISHA (JP) 2011-11-17 US disclosed
WO-2010104199-A2 DIOL, AND POLYCARBONATE RESIN OR POLYESTER RESIN CANON KABUSHIKI KAISHA (JP) 2010-09-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110282025-A1 DIOL, AND POLYCARBONATE RESIN OR POLYESTER RESIN RER1, DHCR24, REV1 LTA4H 1606/4885PTGS1 493/4885PTGS2 1248/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.