Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.35 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.32 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8070311 | 0.92 | CYP1A2 (0.40) | CYP1A2CYP2C9CYP2C19LMNATSHR | |
| SCHEMBL8074794 | 0.90 | CYP1A2 (0.40) | CYP1A2CYP2C9CYP2C19LMNATSHR | |
| SCHEMBL8070650 | 0.83 | L3MBTL1 (0.45) | TSHRL3MBTL1MEN1KMT2A | |
| SCHEMBL8059319 | 0.82 | CYP1A2 (0.39) | CYP1A2CYP2C9CYP2C19LMNATSHR | |
| SCHEMBL8074868 | 0.81 | TBXAS1 (0.47) | TBXAS1L3MBTL1KMT2A | |
| SCHEMBL8073700 | 0.80 | ALDH1A1 (0.39) | TSHRCYP4F2CYP4A11POLBL3MBTL1 | |
| SCHEMBL8059314 | 0.75 | CYP4F2 (0.33) | CYP4F2CYP4A11TBXAS1L3MBTL1MAPT | |
| SCHEMBL15412981 | 0.73 | DRD2 (0.41) | LMNASLC1A3SLC1A2SLC1A1TBXAS1 | |
| SCHEMBL15412571 | 0.73 | DRD2 (0.41) | LMNASLC1A3SLC1A2SLC1A1TBXAS1 | |
| SCHEMBL13610226 | 0.73 | DRD2 (0.41) | LMNASLC1A3SLC1A2SLC1A1TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6030993-A | INHIBITORS OF CARNITINE PALMITOYL TRANSFERASE; ANTIDIABETIC,-LIPEMIC AND HYPOGLYCEMIC AGENTS; SIDE EFFECT REDUCTION | SANG SUP JEW (KR) | 2000-02-29 | — | — | US | disclosed |
| WO-1998000389-A1 | 2-HYDROXYPROPIONIC ACID DERIVATIVE AND ITS MANUFACTURING METHOD | JEW SANG SUP (KR) | 1998-01-08 | — | — | WO | disclosed |