Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | SLC26A6 | Q9BXS9 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.32 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8059319 | 0.92 | CYP1A2 (0.39) | CYP1A2CYP2C9CYP2C19CYP4F2CYP4A11 | |
| SCHEMBL8068601 | 0.90 | CYP1A2 (0.40) | CYP1A2CYP2C9CYP2C19CYP4F2CYP4A11 | |
| SCHEMBL8070311 | 0.82 | CYP1A2 (0.40) | CYP1A2CYP2C9CYP2C19CYP4F2CYP4A11 | |
| SCHEMBL8070650 | 0.75 | L3MBTL1 (0.45) | TSHR | |
| SCHEMBL8068344 | 0.75 | LNPEP (0.40) | CYP1A2CYP2C9CYP2C19PTGESALOX5 | |
| SCHEMBL8073700 | 0.74 | ALDH1A1 (0.39) | CYP4F2CYP4A11TSHR | |
| SCHEMBL15412417 | 0.73 | DRD2 (0.47) | LMNATSHRPTGESALOX5DRD2 | |
| SCHEMBL8074868 | 0.73 | TBXAS1 (0.47) | — | |
| SCHEMBL19474668 | 0.72 | DRD2 (0.49) | LMNAPTGESALOX5CHRM5CHRM1 | |
| SCHEMBL8070349 | 0.72 | CYP4F2 (0.35) | CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6030993-A | INHIBITORS OF CARNITINE PALMITOYL TRANSFERASE; ANTIDIABETIC,-LIPEMIC AND HYPOGLYCEMIC AGENTS; SIDE EFFECT REDUCTION | SANG SUP JEW (KR) | 2000-02-29 | — | — | US | disclosed |