Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8059386 | 0.92 | ALDH1A1 (0.38) | ALDH1A1TSHRNPC1RAB9AHSD17B10 | |
| SCHEMBL8070650 | 0.81 | L3MBTL1 (0.45) | ALDH1A1TSHRMEN1KMT2AMAPK1 | |
| SCHEMBL8068601 | 0.80 | CYP1A2 (0.40) | TSHRHSD17B10MEN1KMT2ACYP4F2 | |
| SCHEMBL8059314 | 0.79 | CYP4F2 (0.33) | ALDH1A1NPC1RAB9ACYP4F2CYP4A11 | |
| SCHEMBL7571177 | 0.77 | NPC1 (0.47) | ALDH1A1TSHRNPC1RAB9AHSD17B10 | |
| SCHEMBL7571500 | 0.76 | TDP1 (0.48) | ALDH1A1TSHRNPC1RAB9AHSD17B10 | |
| SCHEMBL8074868 | 0.76 | TBXAS1 (0.47) | ALDH1A1SMN1; SMN2KMT2AKDM4EHPGD | |
| SCHEMBL7578408 | 0.74 | TDP1 (0.46) | ALDH1A1TSHRNPC1RAB9AHSD17B10 | |
| SCHEMBL8070653 | 0.74 | TDP1 (0.51) | NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL8074794 | 0.74 | CYP1A2 (0.40) | TSHRCYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6030993-A | INHIBITORS OF CARNITINE PALMITOYL TRANSFERASE; ANTIDIABETIC,-LIPEMIC AND HYPOGLYCEMIC AGENTS; SIDE EFFECT REDUCTION | SANG SUP JEW (KR) | 2000-02-29 | — | — | US | disclosed |
| WO-1998000389-A1 | 2-HYDROXYPROPIONIC ACID DERIVATIVE AND ITS MANUFACTURING METHOD | JEW SANG SUP (KR) | 1998-01-08 | — | — | WO | disclosed |