Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8444243 | 0.86 | ALDH1A1 (0.53) | ALDH1A1MAPK1GFERSMN1; SMN2KMT2A | |
| Hydrochloric Acid SCHEMBL8070683 | 0.85 | ALDH1A1 (0.52) | ALDH1A1MAPK1GFERSMN1; SMN2KMT2A | |
| SCHEMBL8447165 | 0.80 | NPSR1 (0.45) | ALDH1A1GFERSMN1; SMN2POLBPKM | |
| SCHEMBL8068934 | 0.80 | SIGMAR1 (0.51) | MAPK1SMN1; SMN2POLBKMT2ASIGMAR1 | |
| Piperidine SCHEMBL8068938 | 0.78 | TSHR (0.42) | ALDH1A1GFERPOLBPKMKMT2A | |
| SCHEMBL8070495 | 0.78 | KDM4E (0.67) | ALDH1A1SMN1; SMN2POLBPKMMAPT | |
| SCHEMBL8073771 | 0.78 | KMT2A (0.58) | ALDH1A1MAPK1SMN1; SMN2POLBPKM | |
| SCHEMBL8068480 | 0.78 | CYP19A1 (0.55) | ALDH1A1POLBKMT2A | |
| SCHEMBL8073502 | 0.78 | TTR (0.51) | ALDH1A1POLBPKMMAPTL3MBTL1 | |
| SCHEMBL8070556 | 0.78 | MAPT (0.47) | MAPK1POLBPKMKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057322-A | USEFUL IN TREATMENT OF CARDIOVASCULAR DISEASES | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-05-02 | — | — | US | disclosed |