Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | FDPS | P14324 | 1/20 | 0.43 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8070393 | 0.87 | ABCB11 (0.51) | MAPTPPARAFDPS | |
| SCHEMBL8712663 | 0.84 | HDAC1 (0.51) | HDAC1HDAC2PPARAFDPSKCNA3 | |
| SCHEMBL8070650 | 0.83 | L3MBTL1 (0.45) | TDP1GAARECQL | |
| SCHEMBL11656460 | 0.82 | TDP1 (0.55) | TDP1HDAC1HDAC2NPC1GAA | |
| SCHEMBL7571528 | 0.81 | DRD2 (0.41) | TDP1HDAC1HDAC2NPC1GAA | |
| SCHEMBL9375026 | 0.79 | TDP1 (0.55) | TDP1NPC1GAAMAPTRAB9A | |
| SCHEMBL7368880 | 0.77 | TDP1 (0.55) | TDP1NPC1GAAMAPTRAB9A | |
| SCHEMBL28729068 | 0.76 | TDP1 (0.55) | TDP1HDAC1HDAC2NPC1GAA | |
| SCHEMBL8074868 | 0.75 | TBXAS1 (0.47) | TDP1SMN1; SMN2 | |
| SCHEMBL8851808 | 0.74 | LTA4H (0.57) | SMN1; SMN2LTA4HKCNA3FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6030993-A | INHIBITORS OF CARNITINE PALMITOYL TRANSFERASE; ANTIDIABETIC,-LIPEMIC AND HYPOGLYCEMIC AGENTS; SIDE EFFECT REDUCTION | SANG SUP JEW (KR) | 2000-02-29 | — | — | US | disclosed |