Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.53 |
| ▸ | ITGB3 | P05106 | 7/20 | 0.50 |
| ▸ | CTSS | P25774 | 6/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.50 |
| ▸ | CTSK | P43235 | 5/20 | 0.50 |
| ▸ | CTSB | P07858 | 4/20 | 0.50 |
| ▸ | SYK | P43405 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | ITGAV | P06756 | 1/20 | 0.49 |
| ▸ | CTSL | P07711 | 3/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5284681 | 0.90 | ITGB3 (0.49) | ACEITGB3CTSSITGA2BCTSK | |
| SCHEMBL5280438 | 0.89 | ITGB3 (0.50) | ACEITGB3CTSSITGA2BCTSK | |
| SCHEMBL5283360 | 0.89 | ITGB3 (0.50) | ACEITGB3CTSSITGA2BCTSK | |
| SCHEMBL4889692 | 0.88 | CTSB (0.47) | ACEITGB3CTSSITGA2BCTSK | |
| SCHEMBL8072127 | 0.87 | ACE (0.60) | ACEITGB3CTSSITGA2BCTSK | |
| SCHEMBL8072132 | 0.87 | ACE (0.60) | ACEITGB3CTSSITGA2BCTSK | |
| SCHEMBL29466819 | 0.85 | CTSL (0.61) | CTSSCTSKCTSBCTSL | |
| SCHEMBL10054782 | 0.84 | ACE (0.59) | ACEITGB3CTSSITGA2BCTSK | |
| SCHEMBL10054705 | 0.84 | ACE (0.59) | ACEITGB3CTSSITGA2BCTSK | |
| SCHEMBL9718080 | 0.84 | SYK (0.57) | ITGB3CTSSITGA2BCTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080838-A | SYNTHETIC CONSTRUCT PREPARED TO HOLD TWO PEPTIDE HELICES IN TIGHT ARRANGEMENT TO MIMIC DNA BINDING CONFORMATION; FOR INVESSTIGATIONAL STUDIES | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2000-06-27 | — | — | US | disclosed |