Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 8/20 | 0.49 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.49 |
| ▸ | TRPM2 | O94759 | 6/20 | 0.47 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | APEX1 | P27695 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8073208 | 1.00 | TRPA1 (0.49) | TRPA1TRPM8TRPM2LTB4RMEN1 | |
| SCHEMBL7830758 | 0.82 | MMP1 (0.48) | MEN1KMT2ASMN1; SMN2ALDH1A1CYP2C19 | |
| SCHEMBL7815807 | 0.81 | NPC1 (0.33) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7822903 | 0.79 | IAPP (0.38) | NPC1RAB9ATDP1GRIK1GRIA1 | |
| SCHEMBL7826959 | 0.78 | TTR (0.41) | KMT2ASMN1; SMN2ALDH1A1KDM4EMAPT | |
| SCHEMBL7826963 | 0.78 | TTR (0.41) | KMT2ASMN1; SMN2ALDH1A1KDM4EMAPT | |
| SCHEMBL7827855 | 0.77 | ALDH1A1 (0.50) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7827848 | 0.77 | ALDH1A1 (0.50) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8068052 | 0.74 | TRPA1 (0.51) | TRPA1TRPM8TRPM2LTB4RMEN1 | |
| SCHEMBL8068049 | 0.74 | TRPA1 (0.51) | TRPA1TRPM8TRPM2LTB4RMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6093714-A | AN ANTIALLERGENS FOR TREATMENT AND PREVENTION OF BRONCHIAL ASTHMA, ECZEMA, HIVES, ALLERGIC GASTROINTESTINAL TROUBLES, ALLERGIC RHINITIS, ALLERGIC CONJUNCTIVITIS | MEIJI SEIKA KAISHA, LTD. (JP) | 2000-07-25 | — | — | US | disclosed |
| EP-0834512-A1 | TRICYCLIC BENZAZEPINE COMPOUNDS | MEIJI SEIKA KAISHA LTD. (JP) | 1998-04-08 | — | — | EP | disclosed |