Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 3/20 | 0.48 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.42 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.42 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.42 |
| ▸ | SCN1A | P35498 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.42 |
| ▸ | PRNP | P04156 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | USP7 | Q93009 | 1/20 | 0.41 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | PI4KA | P42356 | 1/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL807327 | 0.76 | HPGD (0.53) | NPC1RAB9A | |
| SCHEMBL790083 | 0.74 | PTGS2 (0.51) | MEN1NPC1RAB9AKMT2A | |
| SCHEMBL791121 | 0.73 | PTGDR2 (0.46) | MAP4K4KCNH2MEN1NPC1RAB9A | |
| SCHEMBL789573 | 0.72 | CDC7 (0.40) | CHEK2MAP4K4KDM4EPRNPMEN1 | |
| SCHEMBL1132053 | 0.71 | HDAC2 (0.57) | KDM4ENPC1RAB9APLK1 | |
| SCHEMBL807030 | 0.71 | MEN1 (0.39) | MAP4K4PRNPMEN1NPC1RAB9A | |
| SCHEMBL8312097 | 0.70 | PLAU (0.62) | CHEK2KDM4EKCNH2MEN1NPC1 | |
| SCHEMBL790790 | 0.69 | ALOX15 (0.50) | KDM4EMEN1NPC1RAB9AKMT2A | |
| SCHEMBL79445 | 0.69 | HDAC2 (0.64) | KDM4ENPC1PLK1 | |
| SCHEMBL789883 | 0.69 | MAP4K4 (0.54) | CHEK2MAP4K4KDM4EMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |