Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29728523 | 0.83 | ALOX15 (0.36) | LMNAHSD17B10CA4ALOX15ATM | |
| SCHEMBL29867963 | 0.80 | LMNA (0.33) | LMNAHSD17B10 | |
| SCHEMBL291087 | 0.78 | THRB (0.35) | THRB | |
| SCHEMBL2434040 | 0.78 | — | — | |
| SCHEMBL13434035 | 0.76 | GAA (0.42) | THRB | |
| SCHEMBL56282 | 0.76 | THRB (0.33) | THRB | |
| SCHEMBL5015809 | 0.76 | THRB (0.33) | THRB | |
| SCHEMBL291088 | 0.76 | ALDH1A1 (0.33) | THRB | |
| SCHEMBL28644495 | 0.76 | ATM (0.35) | LMNAHSD17B10ALOX15ATM | |
| SCHEMBL20109904 | 0.74 | ELANE (0.32) | THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3874 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12060334-B2 | 3-substituted phenazine derivatives as antimicrobial agents | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2024-08-13 | — | — | US | claimed |
| EP-3715346-B1 | THIAZOLYL-CONTAINING COMPOUNDS FOR TREATING PROLIFERATIVE DISEASES | DANA FARBER CANCER INST INC (US) | 2024-01-03 | — | — | EP | claimed |
| EP-2970107-B1 | PHOTOSWITCHABLE HDAC INHIBITORS | MASSACHUSETTS GEN HOSPITAL (US) | 2023-11-15 | — | — | EP | claimed |
| EP-3606528-B1 | TRICYCLIC COMPOUNDS AS GLYCOGEN SYNTHASE KINASE 3 (GSK3) INHIBITORS AND USES THEREOF | BROAD INST INC (US) | 2023-10-18 | — | — | EP | claimed |
| EP-3291676-B1 | MITRAGYNINE ANALOGS AND USES THEREOF | MEMORIAL SLOAN KETTERING CANCER CENTER (US) | 2022-08-17 | — | — | EP | claimed |
| US-11241435-B2 | Uses of salt-inducible kinase (SIK) inhibitors for treating osteoporosis | THE GENERAL HOSPITAL CORPORATION (US) | 2022-02-08 | — | — | US | claimed |
| EP-3172213-B1 | MACROCYCLIC KINASE INHIBITORS AND USES THEREOF | DANA FARBER CANCER INST INC (US) | 2021-09-22 | — | — | EP | claimed |
| EP-3092220-B1 | VITAMIN C PRODRUGS AND USES THEREOF | UNIV FLORIDA (US) | 2021-01-20 | — | — | EP | claimed |
| US-10870651-B2 | Inhibitors of cyclin-dependent kinase 7 (CDK7) | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2020-12-22 | — | — | US | claimed |
| EP-3171874-B1 | IMIDAZOLYL KINASE INHIBITORS AND USES THEREOF | DANA FARBER CANCER INST INC (US) | 2020-11-18 | — | — | EP | claimed |
| US-10711036-B2 | MALT1 inhibitors and uses thereof | CORNELL UNIVERSITY (US) | 2020-07-14 | — | — | US | claimed |
| EP-2016044-B1 | PENTACYCLINE DERIVATIVES FOR THE TREATMENT OF INFECTIONS | HARVARD COLLEGE (US) | 2020-06-10 | — | — | EP | claimed |
| EP-3209648-B1 | THIAZOLYL-CONTAINING COMPOUNDS FOR TREATING PROLIFERATIVE DISEASES | DANA FARBER CANCER INST INC (US) | 2020-03-11 | — | — | EP | claimed |
| US-10112957-B2 | Thiazolyl-containing compounds for treating proliferative diseases | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2018-10-30 | — | — | US | claimed |
| US-9856225-B2 | Substituted phenazines as antimicrobial agents | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2018-01-02 | — | — | US | claimed |
| EP-2646411-B1 | PREPARATION OF PET PRECURSOR | BLUE EARTH DIAGNOSTICS LTD (GB) | 2017-08-16 | — | — | EP | claimed |
| EP-2550285-B1 | TRIOXACARCINS AND USES THEREOF | HARVARD COLLEGE (US) | 2017-07-19 | — | — | EP | claimed |
| US-20150376201-A1 | CORTISTATIN ANALOGUES AND SYNTHESES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-12-31 | — | — | US | claimed |
| US-20130304089-A1 | PERYLENEQUINONE DERIVATIVES AND USES THEREOF | QUEST PHARMATECH INC. (CA) | 2013-11-14 | — | — | US | claimed |
| US-12637672-B2 | Oligonucleotide compositions and methods thereof | WAVE LIFE SCIENCES LTD. (SG) | 2026-05-26 | — | — | US | disclosed |
| US-12637453-B2 | Pyrazolopyridine inhibitors of c-Jun-n-Terminal kinases and uses thereof | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2026-05-26 | — | — | US | disclosed |
| US-12637463-B2 | Tricyclic kinase inhibitors and uses thereof | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2026-05-26 | — | — | US | disclosed |
| US-20260137789-A1 | BRUSH PRODRUGS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2026-05-21 | — | — | US | disclosed |
| US-20260137806-A1 | INTERCALATING SUGAR MOLECULES | XALUD THERAPEUTICS, INC. (US) | 2026-05-21 | — | — | US | disclosed |
| WO-2026107134-A1 | USE OF SMALL MOLECULE GLUTAMINASE INHIBITORS FOR TREATING AGE-RELATED DISORDERS | LEAL THERAPEUTICS, INC. (US) | 2026-05-21 | — | — | WO | disclosed |
| WO-2026107431-A1 | STEREOSELECTIVE SYNTHESIS OF L,2-CIS-2-AMINOGLYCOSIDES | BRANDEIS UNIVERSITY (US) | 2026-05-21 | — | — | WO | disclosed |
| US-20260132121-A1 | INHIBITORS OF RIPK2 AND MEDICAL USES THEREOF | ODYSSEY THERAPEUTICS INC (US) | 2026-05-14 | — | — | US | disclosed |
| US-20260132237-A1 | FUNCTIONAL OLIGOMERS AND FUNCTIONAL POLYMERS INCLUDING HYDROXYLATED POLYMERS AND CONJUGATES THEREOF AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2026-05-14 | — | — | US | disclosed |
| US-20260132404-A1 | MODIFIED OLIGONUCLEOTIDES AND DOUBLE-STRANDED RNAS | ALNYLAM PHARMACEUTICALS, INC. (US) | 2026-05-14 | — | — | US | disclosed |
| EP-3468946-B1 | CO-CRYSTALS OF LITHIUM BENZOATE AND USES THEREOF | SYNEURX INT TAIWAN CORP (TW) | 2026-05-13 | — | — | EP | disclosed |
| EP-4741399-A1 | LINCOSAMIDE ANTIBIOTICS AND USES THEREOF | President And Fellows Of Harvard College (US) | 2026-05-13 | — | — | EP | disclosed |
| US-12624018-B1 | Inhibitors of RIPK2 and medical uses thereof | ODYSSEY THERAPEUTICS, INC. (US) | 2026-05-12 | — | — | US | disclosed |
| US-12622901-B2 | Compounds for tau protein degradation | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2026-05-12 | — | — | US | disclosed |
| US-20260125367-A1 | CANCER TREATMENTS TARGETING CANCER STEM CELLS | REMEDY PLAN, INC. (US) | 2026-05-07 | — | — | US | disclosed |
| EP-4737470-A2 | C10-ALKYLENE SUBSTITUTED 13-MEMBERED MACROLIDES AND USES THEREOF | Zikani Therapeutics, Inc. (US) | 2026-05-06 | — | — | EP | disclosed |
| EP-4734976-A2 | AGENTS FOR TREATING DISORDERS INVOLVING RYANODINE RECEPTORS | RyCarma Therapeutics, Inc. (US) | 2026-05-06 | — | — | EP | disclosed |
| EP-4735534-A2 | BENZOTHIAZOLE DYES | Detect, Inc. (US) | 2026-05-06 | — | — | EP | disclosed |
| US-12617790-B2 | Mitragynine analogs and uses thereof | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2026-05-05 | — | — | US | disclosed |
| US-20260115280-A1 | VACCINES | ADJUVANCE TECH INC (US) | 2026-04-30 | — | — | US | disclosed |
| US-20260115281-A1 | TRITERPENE SAPONIN ANALOGUES | ADJUVANCE TECH INC (US) | 2026-04-30 | — | — | US | disclosed |
| US-20260116910-A1 | POLYCYCLIC COMPOUNDS AND METHODS THEREOF | HEPAITECH BEIJING BIOPHARMA TECH CO LTD (CN) | 2026-04-30 | — | — | US | disclosed |
| WO-2026090589-A1 | HETEROCYCLIC HBS1L DEGRADERS | TANGO THERAPEUTICS, INC. (US) | 2026-04-30 | — | — | WO | disclosed |
| WO-2026089784-A2 | COMPOUNDS AND COMPOSITIONS FOR CONJUGATION TO BIOLIGANDS FOR IMAGING AND RADIOPHARMACEUTICAL APPLICATIONS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2026-04-30 | — | — | WO | disclosed |
| EP-3743068-B1 | COMPOUNDS FOR THE TREATMENT OF KINASE-DEPENDENT DISORDERS | EXELIXIS INC (US) | 2026-04-29 | — | — | EP | disclosed |
| EP-4074694-B1 | AMINO ACID-, PEPTIDE- AN POLYPEPTIDE-LIPIDS, ISOMERS, COMPOSITIONS, AN USES THEREOF | MASSACHUSETTS INST TECHNOLOGY (US) | 2026-04-29 | — | — | EP | disclosed |
| US-12611456-B2 | Use of thiazole amide compounds for modulating human immune response | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2026-04-28 | — | — | US | disclosed |
| US-12612368-B2 | Cancer treatments targeting cancer stem cells | REMEDY PLAN, INC. (US) | 2026-04-28 | — | — | US | disclosed |
| US-20260109696-A1 | SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS | Interdict Bio, Inc. (US) | 2026-04-23 | — | — | US | disclosed |
| EP-3125943-B1 | PHOSPHATE BASED LINKERS FOR INTRACELLULAR DELIVERY OF DRUG CONJUGATES | MERCK SHARP & DOHME LLC (US) | 2026-04-22 | — | — | EP | disclosed |
| EP-4727530-A2 | ION CHANNEL BINDERS AND USES THEREOF | President and Fellows of Harvard College (US) | 2026-04-22 | — | — | EP | disclosed |
| EP-4727929-A2 | 5'-MODIFIED MONOMERS, OLIGONUCLEOTIDES AND DOUBLE-STRANDED RNAS | Alnylam Pharmaceuticals, Inc. (US) | 2026-04-22 | — | — | EP | disclosed |
| EP-4727647-A1 | GLYCOGEN SYNTHASE KINASE 3 INHIBITORS AND USES THEREOF | The Broad Institute Inc. (US) | 2026-04-22 | — | — | EP | disclosed |
| US-20260103465-A1 | GLYCOGEN SYNTHASE KINASE 3 INHIBITORS AND USES THEREOF | THE BROAD INSTITUTE, INC. (US) | 2026-04-16 | — | — | US | disclosed |
| EP-4724417-A1 | TRICINE AND CITRIC ACID-BASED CATIONIC LIPIDS WITH AROMATIC HEAD GROUPS | Sanofi (FR) | 2026-04-15 | — | — | EP | disclosed |
| EP-4724418-A1 | TRICINE AND CITRIC ACID-BASED CATIONIC LIPIDS | Sanofi (FR) | 2026-04-15 | — | — | EP | disclosed |
| EP-4724456-A1 | STEROL-BASED CATIONIC LIPIDS WITH AROMATIC HEAD GROUPS | Sanofi (FR) | 2026-04-15 | — | — | EP | disclosed |
| EP-4724080-A2 | STAPLED PEPTIDES AND METHODS THEREOF | Parabilis Medicines, Inc. (US) | 2026-04-15 | — | — | EP | disclosed |
| US-20260097120-A1 | INDUCTION OF STEM-LIKE ACTIVATED T CELLS | PHIO PHARMACEUTICALS CORP. (US) | 2026-04-09 | — | — | US | disclosed |
| US-20260092040-A1 | SYNTHESIS OF CYCLOPROPANE CARBOXYLIC ACIDS | PAPAIOANNOU NIKOLAOS (US) | 2026-04-02 | — | — | US | disclosed |
| EP-4717314-A2 | 3,3 DISUBSTITUTED 19-NOR PREGNANE COMPOUNDS, COMPOSITIONS, AND USES THEREOF | Sage Therapeutics, LLC (US) | 2026-04-01 | — | — | EP | disclosed |
| US-12590084-B2 | Oxadiazole HDAC6 inhibitors and uses thereof | EIKONIZO THERAPEUTICS, INC. (US) | 2026-03-31 | — | — | US | disclosed |
| US-12590115-B2 | Technologies useful for oligonucleotide preparation | WAVE LIFE SCIENCES LTD. (SG) | 2026-03-31 | — | — | US | disclosed |
| EP-4712970-A2 | COMPOUNDS FOR TREATING HEREDITARY SPASTIC PARAPLEGIA | The Children's Medical Center Corporation (US) | 2026-03-25 | — | — | EP | disclosed |
| US-12582644-B2 | O-GlcNAc transferase inhibitors and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2026-03-24 | — | — | US | disclosed |
| US-12583817-B2 | Ionizable lipids and compositions and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2026-03-24 | — | — | US | disclosed |
| US-20260078126-A1 | BICYCLIC UREA KINASE INHIBITORS AND USES THEREOF | THE BROAD INSTITUTE, INC. (US) | 2026-03-19 | — | — | US | disclosed |
| US-20260076989-A1 | OLIGONUCLEOTIDES, COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD (SG) | 2026-03-19 | — | — | US | disclosed |
| US-20260078116-A1 | SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS | Interdict Bio, Inc. (US) | 2026-03-19 | — | — | US | disclosed |
| US-20260078117-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS INC (US) | 2026-03-19 | — | — | US | disclosed |
| EP-4709779-A1 | POLYPROLINE-BASED BLOCK COPOLYMERS | Polypeptide Therapeutic Solutions, S.L. (ES) | 2026-03-18 | — | — | EP | disclosed |
| EP-4709715-A1 | DECREASING THE INTRINSICALLY DISORDERED PROTEIN ALPHA-SYNUCLEIN'S LEVELS BY TARGETING ITS STRUCTURED MRNA WITH A RIBONUCLEASE TARGETING CHIMERA | University of Florida Research Foundation, Incorporated (US) | 2026-03-18 | — | — | EP | disclosed |
| EP-4709372-A1 | SMALL MOLECULE INHIBITORS OF GLUTAMINASE | Leal Therapeutics, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| EP-4709735-A1 | OLIGONUCLEOTIDE SYNTHESIS USING CYCLIC-PHOSPHOROUS NUCLEOSIDES | Eli Lilly and Company (US) | 2026-03-18 | — | — | EP | disclosed |
| US-20260070917-A1 | CYCLIN DEPENDENT KINASE DEGRADERS AND METHODS OF USE THEREOF | DIFFERENTIATED THERAPEUTICS INC (US) | 2026-03-12 | — | — | US | disclosed |
| US-20260069700-A1 | BRUSH PRODRUGS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2026-03-12 | — | — | US | disclosed |
| US-12569554-B2 | Triterpene saponin analogues | ADJUVANCE TECHNOLOGIES, INC. (US) | 2026-03-10 | — | — | US | disclosed |
| US-20260062426-A1 | CYCLIN DEPENDENT KINASE DEGRADERS AND METHODS OF USE THEREOF | DIFFERENTIATED THERAPEUTICS INC (US) | 2026-03-05 | — | — | US | disclosed |
| EP-4702004-A1 | NONIONIC SURFACTANTS | Detect, Inc. (US) | 2026-03-04 | — | — | EP | disclosed |
| EP-3908583-B1 | DOT1L DEGRADERS AND USES THEREOF | DANA FARBER CANCER INST INC (US) | 2026-03-04 | — | — | EP | disclosed |
| US-12564591-B2 | HCK as a therapeutic target in MYD88 mutated diseases | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2026-03-03 | — | — | US | disclosed |
| US-20260055090-A1 | OXADIAZOLE HDAC6 INHIBITORS AND USES THEREOF | EIKONIZO THERAPEUTICS, INC. (US) | 2026-02-26 | — | — | US | disclosed |
| WO-2026043875-A1 | SYNTHESIS OF OXEPANOPROLINES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2026-02-26 | — | — | WO | disclosed |
| EP-4698224-A1 | SAPONIN DERIVATIVES AS ADJUVANTS AND PHOTOAFFINITY PROBES | Asociación Centro de Investigación Cooperativa en Biociencias - CIC bioGUNE (ES) | 2026-02-25 | — | — | EP | disclosed |
| US-12553050-B2 | Compositions and methods for inhibiting cytochrome P450 family 7 subfamily a member 1 (CYP7A1) expression | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2026-02-17 | — | — | US | disclosed |
| US-12552743-B2 | Oligonucleotide compositions and methods of use thereof | WAVE LIFE SCIENCES LTD. (SG) | 2026-02-17 | — | — | US | disclosed |
| US-12552830-B2 | Steroidal compound derivatives as therapeutic agents | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2026-02-17 | — | — | US | disclosed |
| US-12552825-B2 | C10-alkylene substituted 13-membered macrolides and uses thereof | Zikani Therapeutics , Inc. (US) | 2026-02-17 | — | — | US | disclosed |
| US-20260043057-A1 | ENZYMATIC SYNTHESIS OF MYCOSPORINE-LIKE AMINO ACIDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2026-02-12 | — | — | US | disclosed |
| EP-3883647-B1 | C10-ALKYLENE SUBSTITUTED 13-MEMBERED MACROLIDES AND USES THEREOF | ZIKANI THERAPEUTICS INC (US) | 2026-02-11 | — | — | EP | disclosed |
| EP-4688758-A1 | VERDAZYL COMPOUNDS AS CONTRAST AGENTS FOR MAGNETIC RESONANCE IMAGING OF KIDNEYS | Yellowbird Diagnostics Inc. (CA) | 2026-02-11 | — | — | EP | disclosed |
| US-12544344-B2 | Topical delivery of nucleic acid compounds | PHIO PHARMACEUTICALS CORP. (US) | 2026-02-10 | — | — | US | disclosed |
| US-20260034071-A1 | HIGH-PURITY PEG LIPIDS AND USES THEREOF | MODERNATX, INC. (US) | 2026-02-05 | — | — | US | disclosed |
| US-20260035402-A1 | C10-ALKYLENE SUBSTITUTED 13-MEMBERED MACROLIDES AND USES THEREOF | ZIKANI THERAPEUTICS INC (US) | 2026-02-05 | — | — | US | disclosed |
| US-RE50776-E1 | Inhibitors of cyclin-dependent kinases | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2026-02-03 | — | — | US | disclosed |
| US-20260028367-A1 | DOT1L DEGRADERS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2026-01-29 | — | — | US | disclosed |
| US-20260027106-A1 | PRMT5 INHIBITORS AND USES THEREOF | Epizyme, Inc. | 2026-01-29 | — | — | US | disclosed |
| US-20260021055-A1 | Asymmetric Piperazine-Based Cationic Lipids | TRANSLATE BIO, INC. (US) | 2026-01-22 | — | — | US | disclosed |
| US-20260023081-A1 | SOLID PHASE LIBRARY PREPARATION FOR POLYPEPTIDE SEQUENCING | Quantum-Si Incorporated (US) | 2026-01-22 | — | — | US | disclosed |
| US-20260021103-A1 | IKZF2 AND CK1-ALPHA DEGRADING COMPOUNDS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2026-01-22 | — | — | US | disclosed |
| US-20260022143-A1 | Cyclic Peptide Inhibitors of IL-23 | JANSSEN PHARMACEUTICA NV (BE) | 2026-01-22 | — | — | US | disclosed |
| US-12528767-B2 | HDAC6 inhibitors and uses thereof | EIKONIZO THERAPEUTICS, INC. (US) | 2026-01-20 | — | — | US | disclosed |
| US-20260015419-A1 | COMBINATION OF MACROPHAGE-DIRECTED IMMUNOTHERAPY AND CYTOKINES FOR TREATMENT OF CANCER | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2026-01-15 | — | — | US | disclosed |
| US-12522587-B2 | Cancer treatments targeting cancer stem cells | REMEDY PLAN, INC. (US) | 2026-01-13 | — | — | US | disclosed |
| US-12521410-B2 | Compounds and pharmaceutical uses thereof | SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) | 2026-01-13 | — | — | US | disclosed |
| US-12522583-B2 | Benzimidazole derivatives and aza-benzimidazole derivatives as Janus kinase 2 inhibitors and uses thereof | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2026-01-13 | — | — | US | disclosed |
| US-20260008764-A1 | BACKBONE CLEAVABLE POLYMETHACRYLATES VIA THIONOLACTONE COMONOEMERS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2026-01-08 | — | — | US | disclosed |
| EP-4673449-A1 | CYCLIN DEPENDENT KINASE DEGRADERS AND METHODS OF USE THEREOF | Differentiated Therapeutics Inc (US) | 2026-01-07 | — | — | EP | disclosed |
| US-20260000775-A1 | a4ß1/7 INTEGRIN LIGAND CONJUGATED COMPOUNDS AND USES THEREOF | ADARX PHARMACEUTICALS, INC. (US) | 2026-01-01 | — | — | US | disclosed |
| US-12509455-B2 | Imidazopyridine derivatives and aza-imidazopyridine derivatives as Janus kinase 2 inhibitors and uses thereof | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2025-12-30 | — | — | US | disclosed |
| US-20250387490-A9 | IONIZABLE LIPIDS FOR MULTIPLE ORGAN TARGETING | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2025-12-25 | — | — | US | disclosed |
| EP-4665332-A2 | CYCLIN DEPENDENT KINASE DEGRADERS AND METHODS OF USE THEREOF | Differentiated Therapeutics Inc (US) | 2025-12-24 | — | — | EP | disclosed |
| US-12503438-B2 | Compounds for the treatment of kinase-dependent disorders | EXELIXIS, INC. (US) | 2025-12-23 | — | — | US | disclosed |
| US-20250382324-A1 | MONOMERS AND METHODS FOR SYNTHESIS OF MODIFIED OLIGONUCLEOTIDES | ALNYLAM PHARMACEUTICALS, INC. (US) | 2025-12-18 | — | — | US | disclosed |
| US-20250382617-A1 | DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS FOR RNA INTERFERENCE AND METHODS RELATING THERETO | WAVE LIFE SCIENCES LTD. (SG) | 2025-12-18 | — | — | US | disclosed |
| EP-3572417-B1 | 3,3 DISUBSTITUTED 19-NOR PREGNANE COMPOUNDS, COMPOSITIONS, AND USES THEREOF | SAGE THERAPEUTICS LLC (US) | 2025-12-17 | — | — | EP | disclosed |
| EP-4658280-A2 | SIX MEMBERED RING CONTAINING OLIGOMERS | Alnylam Pharmaceuticals, Inc. (US) | 2025-12-10 | — | — | EP | disclosed |
| US-12492225-B2 | Melanocyte-regulating peptides | IDP DISCOVERY PHARMA, S.L. (ES) | 2025-12-09 | — | — | US | disclosed |
| US-20250367294-A1 | BRANCHED MULTI-FUNCTIONAL MACROMONOMERS AND RELATED POLYMERS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2025-12-04 | — | — | US | disclosed |
| US-12486289-B2 | Tricyclic compounds as glycogen synthase kinase 3 (GSK3) inhibitors and uses thereof | THE BROAD INSTITUTE, INC. (US) | 2025-12-02 | — | — | US | disclosed |
| US-12486505-B2 | Oligonucleotide compositions and methods thereof | WAVE LIFE SCIENCES LTD. (SG) | 2025-12-02 | — | — | US | disclosed |
| US-12478616-B2 | PI3K inhibitors and uses thereof | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2025-11-25 | — | — | US | disclosed |
| US-12478682-B2 | Nucleic acid conjugates and uses thereof | TRANSLATE BIO MA, INC. (US) | 2025-11-25 | — | — | US | disclosed |
| US-12478683-B2 | Brush prodrugs and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2025-11-25 | — | — | US | disclosed |
| US-20250352452-A1 | CLEAVABLE COMONOMER STRATEGY FOR ACCELERATING REMOVAL OF GEL NAIL POLISH | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2025-11-20 | — | — | US | disclosed |
| EP-4648762-A2 | PPARG MODULATORS | University of Florida Research Foundation, Incorporated (US) | 2025-11-19 | — | — | EP | disclosed |
| US-20250346943-A1 | DEGRADER COMPOUNDS OF QSOX1 mRNA | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2025-11-13 | — | — | US | disclosed |
| EP-4646401-A1 | NOVEL IONIZABLE LIPID COMPOUNDS FOR NUCLEIC ACID DELIVERY | CELON PHARMA S.A. (PL) | 2025-11-12 | — | — | EP | disclosed |
| EP-4647127-A2 | COMPOUNDS FOR THE TREATMENT OF KINASE-DEPENDENT DISORDERS | Exelixis, Inc. (US) | 2025-11-12 | — | — | EP | disclosed |
| US-20250341526-A1 | NOVEL DYES | Quantum-Si Incorporated (US) | 2025-11-06 | — | — | US | disclosed |
| EP-4642434-A2 | LIPID COMPOSITIONS ON THE BASIS OF IONIZABLE LIPIDS, USE FOR DELIVERY TO IMMUNE CELLS | Life Technologies Corporation (US) | 2025-11-05 | — | — | EP | disclosed |
| US-12458700-B2 | Amine-containing transfection reagents and methods for making and using same | Life Technologies Corporation (US) | 2025-11-04 | — | — | US | disclosed |
| US-20250333740-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD (SG) | 2025-10-30 | — | — | US | disclosed |
| EP-4638415-A1 | BIS-ESTER AND AMIDE CATIONIC LIPIDS | Sanofi Pasteur Inc. (US) | 2025-10-29 | — | — | EP | disclosed |
| EP-3774767-B1 | ARYL HYDROCARBON RECEPTOR MODULATORS AND USES THEREOF | BETH ISRAEL DEACONESS MEDICAL CT INC (US) | 2025-10-29 | — | — | EP | disclosed |
| US-20250325659-A1 | USE OF TOLL-LIKE RECEPTOR 2 (TLR-2) AGONIST FOR MODULATING HUMAN IMMUNE RESPONSE | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2025-10-23 | — | — | US | disclosed |
| US-20250326777-A1 | COMPOUNDS, COMPOSITIONS AND METHODS THEREOF | HEPAITECH BEIJING BIOPHARMA TECH CO LTD (CN) | 2025-10-23 | — | — | US | disclosed |
| EP-4633657-A1 | STAPLED PEPTIDES AND METHODS THEREOF | Parabilis Medicines, Inc. (US) | 2025-10-22 | — | — | EP | disclosed |
| EP-4633656-A1 | STAPLED PEPTIDES AND METHODS THEREOF | Parabilis Medicines, Inc. (US) | 2025-10-22 | — | — | EP | disclosed |
| US-20250319025-A9 | COMPOSITIONS COMPRISING MODIFIED PHOSPHOLIPIDS AND USES THEREOF | THE CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2025-10-16 | — | — | US | disclosed |
| EP-3737362-B1 | COMBINATION OF A SELECTIVE HISTONE DEACETYLASE 3 (HDAC3) INHIBITOR AND AN IMMUNOTHERAPY AGENT FOR THE TREATMENT OF CANCER | KDAC THERAPEUTICS INC (US) | 2025-10-15 | — | — | EP | disclosed |
| EP-4630397-A1 | IONIZABLE LIPIDS WITH MALONATE TAILS | ModernaTX, Inc. (US) | 2025-10-15 | — | — | EP | disclosed |
| US-12440323-B2 | Method of delivering a urological device into a bladder neck or urethra of a user | COLOPLAST A/S (DK) | 2025-10-14 | — | — | US | disclosed |
| US-20250312367-A1 | OLIGONUCLEOTIDES HAVING A SYNTHETIC BACKBONE AND SYNTHESIS THEREOF | ADARX PHARMACEUTICALS, INC. (US) | 2025-10-09 | — | — | US | disclosed |
| US-20250313530-A1 | SMALL MOLECULE INHIBITORS OF INTERLEUKIN-4 AND USES THEREOF | TRUSTEES OF BOSTON UNIVERSITY (US) | 2025-10-09 | — | — | US | disclosed |
| US-20250313836-A1 | CHIRAL DESIGN | WAVE LIFE SCIENCES LTD (SG) | 2025-10-09 | — | — | US | disclosed |
| US-20250313563-A1 | GLYCOGEN SYNTHASE KINASE 3 INHIBITORS AND USES THEREOF | THE BROAD INSTITUTE, INC. (US) | 2025-10-09 | — | — | US | disclosed |
| EP-4626385-A1 | CLEAVABLE COMONOMER STRATEGY FOR ACCELERATING REMOVAL OF GEL NAIL POLISH | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2025-10-08 | — | — | EP | disclosed |
| US-12435028-B2 | Processes for the preparation of (S)-tert-butyl 4,5-diamino-5-oxopentanoate | CELGENE CORPORATION (US) | 2025-10-07 | — | — | US | disclosed |
| US-12435088-B2 | Salicyl-adenosinemonosulfamate analogs and uses thereof | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2025-10-07 | — | — | US | disclosed |
| US-20250304613-A1 | AMINOOXY CLICK CHEMISTRY (AOCC): A VERSATILE CONJUGATION APPROACH | ALNYLAM PHARMACEUTICALS, INC. (US) | 2025-10-02 | — | — | US | disclosed |
| US-20250304571-A1 | BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF | SUZHOU KEEN THERAPEUTICS CO., LTD. (CN) | 2025-10-02 | — | — | US | disclosed |
| US-20250302995-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | SHIVALILA CHIKDU SHAKTI (US) | 2025-10-02 | — | — | US | disclosed |
| EP-3664799-B1 | LINCOSAMIDE ANTIBIOTICS AND USES THEREOF | HARVARD COLLEGE (US) | 2025-10-01 | — | — | EP | disclosed |
| EP-4622970-A1 | INHIBITORS OF RIPK2 AND MEDICAL USES THEREOF | ODYSSEY THERAPEUTICS, INC. (US) | 2025-10-01 | — | — | EP | disclosed |
| US-12427196-B2 | Macromolecular prodrugs for light-emitting diodes and uses thereof | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2025-09-30 | — | — | US | disclosed |
| US-20250297260-A1 | COMPOSITIONS AND METHODS FOR INHIBITING CYTOCHROME P450 FAMILY 7 SUBFAMILY A MEMBER 1 (CYP7A1) EXPRESSION | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2025-09-25 | — | — | US | disclosed |
| EP-3947382-B1 | COMPOUNDS FOR USES IN PHARMACOLOGICAL INDUCTION OF HBF FOR TREATMENT OF SICKLE CELL DISEASE AND BETA-THALASSEMIA | ACADEMIA SINICA (TW) | 2025-09-24 | — | — | EP | disclosed |
| EP-3236959-B1 | INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 (CDK7) | DANA FARBER CANCER INST INC (US) | 2025-09-24 | — | — | EP | disclosed |
| US-12419885-B2 | Kinase inhibitors and methods of use thereof | THE BROAD INSTITUTE, INC. (US) | 2025-09-23 | — | — | US | disclosed |
| EP-3814365-B1 | DOT1L DEGRADER AND USES THEREOF | DANA FARBER CANCER INST INC (US) | 2025-09-17 | — | — | EP | disclosed |
| US-12414997-B2 | Brush prodrugs and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2025-09-16 | — | — | US | disclosed |
| US-12415816-B2 | Benzothiazole derivatives and 7-aza-benzothiazole derivatives as janus kinase 2 inhibitors and uses thereof | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2025-09-16 | — | — | US | disclosed |
| US-20250282749-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. | 2025-09-11 | — | — | US | disclosed |
| US-12403137-B2 | Compounds and methods of use | TANGO THERAPEUTICS, INC. (US) | 2025-09-02 | — | — | US | disclosed |
| US-12403156-B2 | Oligonucleotides, compositions and methods thereof | WAVE LIFE SCIENCES LTD. (SG) | 2025-09-02 | — | — | US | disclosed |
| US-20250270179-A1 | TRICYCLO-DNA NUCLEOSIDE PRECURSORS AND PROCESSES FOR PREPARING THE SAME | SYNTHENA AG (CH) | 2025-08-28 | — | — | US | disclosed |
| US-20250270246-A1 | LINCOSAMIDES AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2025-08-28 | — | — | US | disclosed |
| EP-4419513-B1 | ANTITUMORAL COMPOUNDS | PHARMA MAR SA (ES) | 2025-08-27 | — | — | EP | disclosed |
| EP-4605374-A1 | COMPOUNDS, COMPOSITIONS AND METHODS THEREOF | Hepaitech (Beijing) Biopharma Technology Co., Ltd. (CN) | 2025-08-27 | — | — | EP | disclosed |
| EP-4605011-A2 | POLYPEPTIDYL LINKERS | Quantum-Si Incorporated (US) | 2025-08-27 | — | — | EP | disclosed |
| US-12398145-B2 | Bicyclic urea kinase inhibitors and uses thereof | THE BROAD INSTITUTE, INC. (US) | 2025-08-26 | — | — | US | disclosed |
| US-20250262235-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO | WAVE LIFE SCIENCES LTD (SG) | 2025-08-21 | — | — | US | disclosed |
| US-20250263385-A1 | \"Good\" buffer-based cationic lipids | SANOFI (FR) | 2025-08-21 | — | — | US | disclosed |
| EP-4601637-A2 | GLYCOGEN SYNTHASE KINASE 3 INHIBITORS AND USES THEREOF | The Broad Institute Inc. (US) | 2025-08-20 | — | — | EP | disclosed |
| US-12390528-B2 | Conjugated lipomers and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2025-08-19 | — | — | US | disclosed |
| US-12391942-B2 | Oligonucleotide compositions and methods of use thereof | WAVE LIFE SCIENCES LTD. (SG) | 2025-08-19 | — | — | US | disclosed |
| US-20250255839-A1 | COMBINATION OF A SELECTIVE HISTONE DEACETYLASE 3 (HDAC3) INHIBITOR AND AN IMMUNOTHERAPY AGENT FOR THE TREATMENT OF CANCER | KDAc Therapeutics, Inc. (US) | 2025-08-14 | — | — | US | disclosed |
| US-20250257092-A1 | NEUROACTIVE STEROIDS, COMPOSITIONS, AND USES THEREOF | Sage Therapeutics, LLC | 2025-08-14 | — | — | US | disclosed |
| EP-4598905-A2 | CEREBLON-RECRUITING BCL-XL/BCL-2 DUAL DEGRADERS | University of Florida Research Foundation, Incorporated (US) | 2025-08-13 | — | — | EP | disclosed |
| US-12384800-B2 | Antitumoral compounds | PHARMA MAR, S.A. (ES) | 2025-08-12 | — | — | US | disclosed |
| US-12383508-B2 | High-purity peg lipids and uses thereof | MODERNATX, INC. (US) | 2025-08-12 | — | — | US | disclosed |
| US-20250250565-A1 | OLIGONUCLEOTIDES CONJUGATES COMPRISING 7'-5'-ALPHA-ANOMERIC-BICYCLIC SUGAR NUCLEOSIDES | ALPHA ANOMERIC SAS (FR) | 2025-08-07 | — | — | US | disclosed |
| US-20250250263-A1 | INHIBITING HISTONE DEACETYLASE 6 (HDAC6) | EIKONIZO THERAPEUTICS, INC. (US) | 2025-08-07 | — | — | US | disclosed |
| EP-4593820-A2 | SMALL MOLECULE DEGRADERS OF HIV-1 TAT PROTEIN | University of Florida Research Foundation, Incorporated (US) | 2025-08-06 | — | — | EP | disclosed |
| US-12377053-B2 | Cationic polymers | TRANSLATE BIO, INC. (US) | 2025-08-05 | — | — | US | disclosed |
| US-12377037-B2 | Cleavable comonomer strategy for accelerating removal of gel nail polish | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2025-08-05 | — | — | US | disclosed |
| US-20250243174-A1 | ANTITUMORAL COMPOUNDS | PHARMA MAR, S.A. (ES) | 2025-07-31 | — | — | US | disclosed |
| US-20250243159-A9 | BIOMOLECULE-POLYMER-PHARMACEUTICAL AGENT CONJUGATES FOR DELIVERING THE PHARMACEUTICAL AGENT | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2025-07-31 | — | — | US | disclosed |
| EP-4590663-A2 | SYNTHESIS OF CYCLOPROPANE CARBOXYLIC ACIDS | Takeda Pharmaceutical Company Limited (JP) | 2025-07-30 | — | — | EP | disclosed |
| EP-4587014-A2 | C5AR1 ANTAGONISTS AND USES THEREOF | Vanqua Bio, Inc. (US) | 2025-07-23 | — | — | EP | disclosed |
| EP-3743070-B1 | COMPOUNDS FOR THE TREATMENT OF KINASE-DEPENDENT DISORDERS | EXELIXIS INC (US) | 2025-07-23 | — | — | EP | disclosed |
| US-12365752-B2 | Functional oligomers and functional polymers including hydroxylated polymers and conjugates thereof and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2025-07-22 | — | — | US | disclosed |
| WO-2025151620-A1 | FUNCTIONALIZED IMIDAZOPYRIMIDINE COMPOUNDS AND USES THEREOF | THE CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2025-07-17 | — | — | WO | disclosed |
| US-20250230166-A1 | OXADIAZOLE HDAC6 INHIBITORS AND USES THEREOF | EIKONIZO THERAPEUTICS, INC. (US) | 2025-07-17 | — | — | US | disclosed |
| US-20250230172-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | VANQUA BIO, INC. (US) | 2025-07-17 | — | — | US | disclosed |
| WO-2025151895-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2025-07-17 | — | — | WO | disclosed |
| WO-2025151874-A1 | INDOLE ALKALOID ANTIPLASMODIAL AGENTS AND PREPARATION THEREOF | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) | 2025-07-17 | — | — | WO | disclosed |
| WO-2025151449-A1 | BIFUNCTIONAL P53-BINDING COMPOUNDS AND USES THEREOF | PHOTYS THERAPEUTICS, INC. (US) | 2025-07-17 | — | — | WO | disclosed |
| US-20250223311-A1 | MINIMAL SAPONIN ANALOGUES, SYNTHESIS AND USE THEREOF | MEMORIAL SLOAN KETTERING CANCER CENTER (US) | 2025-07-10 | — | — | US | disclosed |
| US-20250223588-A1 | OLIGONUCLEOTIDES WITH 2'-DEOXY-2'-F-2'-C-METHYL NUCLEOTIDES | ALNYLAM PHARMACEUTICALS, INC. (US) | 2025-07-10 | — | — | US | disclosed |
| EP-4580686-A1 | HALOGENATED SOMATOSTATIN ANALOGS WITH MULTIPLE SOMATOSTATIN RECEPTOR SUBTYPE SELECTIVITY | Grafton Therapeutics Sàrl (CH) | 2025-07-09 | — | — | EP | disclosed |
| WO-2025130765-A1 | COMPOUNDS, COMPOSITIONS AND METHODS THEREOF | HEPAITECH (BEIJING) BIOPHARMA TECHNOLOGY CO., LTD. (CN) | 2025-06-26 | — | — | WO | disclosed |
| WO-2025072862-A9 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2025-06-26 | — | — | WO | disclosed |
| US-20250205158-A1 | BIODEGRADABLE LIPIDS AND FORMULATIONS FOR DELIVERY OF MRNA | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2025-06-26 | — | — | US | disclosed |
| US-20250195689-A1 | GLYCOMIMETIC LIGANDS | AVICEDA THERAPEUTICS, INC. | 2025-06-19 | — | — | US | disclosed |
| WO-2025128639-A1 | HYDROGELS COMPRISING PROTEIN-STABILIZED NANOPARTICLES FOR EXTENDED RELEASE | THE CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2025-06-19 | — | — | WO | disclosed |
| WO-2025129024-A1 | CEREBLON-RECRUITING DEGRADERS OF ANTIAPOPTOTIC BCL-2 PROTEINS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2025-06-19 | — | — | WO | disclosed |
| WO-2025124599-A1 | BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF | SUZHOU KEEN THERAPEUTICS CO., LTD. (CN) | 2025-06-19 | — | — | WO | disclosed |
| EP-3872067-B1 | PROLINE DERIVATIVES | HARVARD COLLEGE (US) | 2025-06-18 | — | — | EP | disclosed |
| US-12331069-B2 | DOT1L degraders and uses thereof | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2025-06-17 | — | — | US | disclosed |
| US-20250188470-A1 | MULTIPLEXING TARGETING LIGANDS THROUGH CLICK CHEMISTRY AT THE ANOMERIC SITE OF SUGARS | ALNYLAM PHARMACEUTICALS, INC. (US) | 2025-06-12 | — | — | US | disclosed |
| WO-2025122865-A1 | BIFUNCTIONAL ABL1-BINDING COMPOUNDS AND USES THEREOF | PHOTYS THERAPEUTICS, INC. (US) | 2025-06-12 | — | — | WO | disclosed |
| US-20250188238-A1 | HYDROPHOBIC POLYMER AEROGELS | AEROGEL TECHNOLOGIES, LLC (US) | 2025-06-12 | — | — | US | disclosed |
| US-20250188109-A1 | TRITERPENE SAPONINS, METHODS OF SYNTHESIS, AND USES THEREOF | SLOAN KETTERING INSITUTE FOR CANCER RES (US) | 2025-06-12 | — | — | US | disclosed |
| EP-4565588-A1 | BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF | Suzhou Keen Therapeutics Co., Ltd. (CN) | 2025-06-11 | — | — | EP | disclosed |
| US-20250179065-A1 | HDAC6 INHIBITORS AND USES THEREOF | EIKONIZO THERAPEUTICS, INC. (US) | 2025-06-05 | — | — | US | disclosed |
| US-20250177391-A1 | INHIBITORS OF DDR1 AND DDR2 FOR THE TREATMENT OF ARTHRITIS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2025-06-05 | — | — | US | disclosed |
| EP-3321268-B1 | BICYCLIC HETEROARYL DERIVATIVES AS MNK1 AND MNK2 MODULATORS AND USES THEREOF | AGENCY SCIENCE TECH & RES (SG) | 2025-06-04 | — | — | EP | disclosed |
| EP-4561631-A2 | MODIFIED OLIGONUCLEOTIDES AND DOUBLE-STRANDED RNAS | Alnylam Pharmaceuticals, Inc. (US) | 2025-06-04 | — | — | EP | disclosed |
| US-12319667-B2 | Tricyclo-DNA nucleoside precursors and processes for preparing the same | SYNTHENA AG (CH) | 2025-06-03 | — | — | US | disclosed |
| US-20250170283-A1 | COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS | LANTHEUS MEDICAL IMAGING, INC. (US) | 2025-05-29 | — | — | US | disclosed |
| US-20250170282-A1 | COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS | LANTHEUS MEDICAL IMAGING, INC. (US) | 2025-05-29 | — | — | US | disclosed |
| US-20250171432-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. | 2025-05-29 | — | — | US | disclosed |
| US-20250171398-A1 | COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS | LANTHEUS MEDICAL IMAGING, INC. (US) | 2025-05-29 | — | — | US | disclosed |
| EP-4558148-A2 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | Amylyx Pharmaceuticals Inc. (US) | 2025-05-28 | — | — | EP | disclosed |
| US-12312377-B2 | Biconjugatable labels and methods of use | Quantum-Si Incorporated (US) | 2025-05-27 | — | — | US | disclosed |
| WO-2025038673-A9 | BACKBONE CLEAVABLE POLYMETHACRYLATES VIA THIONOLACTONE COMONOEMERS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2025-05-22 | — | — | WO | disclosed |
| US-20250161459-A1 | TRKB LIGAND CONJUGATED COMPOUNDS AND USES THEREOF | ADARX PHARMACEUTICALS, INC. (US) | 2025-05-22 | — | — | US | disclosed |
| WO-2025104706-A2 | SMALL MOLECULE MODULATORS OF MAS AND MRGD RECEPTORS | XITRA THERAPEUTICS GMBH (DE) | 2025-05-22 | — | — | WO | disclosed |
| US-20250163048-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. | 2025-05-22 | — | — | US | disclosed |
| EP-4554671-A1 | CYCLIC PEPTIDE INHIBITORS OF IL-23 | JANSSEN Pharmaceutica NV (BE) | 2025-05-21 | — | — | EP | disclosed |
| US-12304907-B2 | Compounds and methods of use | TANGO THERAPEUTICS, INC. (US) | 2025-05-20 | — | — | US | disclosed |
| US-20250154323-A1 | THIONOLACTONES AS ADDITIVES FOR VINYL NETWORK DEGRADATION | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2025-05-15 | — | — | US | disclosed |
| US-20250152518-A1 | PEG LIPIDS AND USES THEREOF | MODERNATX, INC. (US) | 2025-05-15 | — | — | US | disclosed |
| WO-2025072883-A9 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2025-05-15 | — | — | WO | disclosed |
| US-20250152611-A1 | IMMUNOMODULATORY LIPIDS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2025-05-15 | — | — | US | disclosed |
| WO-2025072886-A9 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2025-05-15 | — | — | WO | disclosed |
| WO-2025101204-A1 | INTRATUMORAL TARGETING OF PD-1 | PHIO PHARMACEUTICALS CORP. (US) | 2025-05-15 | — | — | WO | disclosed |
| WO-2025072879-A9 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2025-05-15 | — | — | WO | disclosed |
| WO-2025072881-A9 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2025-05-15 | — | — | WO | disclosed |
| WO-2025092922-A1 | COMPOUNDS, COMPOSITIONS AND METHODS THEREOF | IONGEN THERAPEUTICS CO., LTD. (CN) | 2025-05-08 | — | — | WO | disclosed |
| US-20250144227-A1 | C-16 MODIFIED TRIOXACARCINS, ANTIBODY DRUG CONJUGATES, AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2025-05-08 | — | — | US | disclosed |
| US-20250144032-A1 | POLY(BETA-AMINO ESTER) MICROPARTICLES FOR MICRONUTRIENT FORTIFICATION | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2025-05-08 | — | — | US | disclosed |
| EP-4547852-A2 | MONOMERS AND METHODS FOR SYNTHESIS OF MODIFIED OLIGONUCLEOTIDES | Alnylam Pharmaceuticals, Inc. (US) | 2025-05-07 | — | — | EP | disclosed |
| US-20250136594-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. | 2025-05-01 | — | — | US | disclosed |
| WO-2025090920-A1 | COMPOSITIONS AND METHODS FOR TREATING DYSFUNCTION OF GLUCOSE METABOLISM AND/OR REGULATION | PITON THERAPEUTICS, INC. (US) | 2025-05-01 | — | — | WO | disclosed |
| US-20250135036-A1 | COMPOSITIONS FOR EDITING MECP2 TRANSCRIPTS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2025-05-01 | — | — | US | disclosed |
| WO-2025090919-A1 | COMPOSITIONS AND METHODS FOR TREATING INFLAMMATORY BOWEL DISEASE | PITON THERAPEUTICS, INC. (US) | 2025-05-01 | — | — | WO | disclosed |
| EP-4543990-A1 | INDOCYANINE GREEN (ICG) MODIFICATION FOR TREATMENT OF LIVER CANCER | The Children's Medical Center Corporation (US) | 2025-04-30 | — | — | EP | disclosed |
| US-20250129021-A1 | SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS | Interdict Bio, Inc. (US) | 2025-04-24 | — | — | US | disclosed |
| WO-2025085758-A1 | MICRO RNA SPONGES USEFUL FOR INCREASING MG29 EXPRESSION AND GLUCOSE UPTAKE AND TREATING METABOLIC DISORDERS | MA JIANJIE (US) | 2025-04-24 | — | — | WO | disclosed |
| US-20250127918-A1 | SITE-SELECTIVE CONJUGATION OF A PHARMACEUTICAL AGENT TO AN ANTIBODY USING AN AFFINITY PEPTIDE | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2025-04-24 | — | — | US | disclosed |
| US-12281126-B2 | Inhibitors of cyclin-dependent kinase 7 and uses thereof | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2025-04-22 | — | — | US | disclosed |
| WO-2025077996-A1 | SYNTHETIC PROCESS FOR THE MANUFACTURE OF ECTEINASCIDIN COMPOUNDS | PHARMA MAR, S.A. (ES) | 2025-04-17 | — | — | WO | disclosed |
| WO-2025080995-A1 | PHARMACEUTICAL AGENT-INTEGRIN LIGAND CONJUGATES FOR MUSCLE DELIVERY | ADARX PHARMACEUTICALS, INC. (US) | 2025-04-17 | — | — | WO | disclosed |
| EP-4536357-A1 | CYCLOPHILIN INHIBITORS AND USES THEREOF | The Broad Institute, Inc. (US) | 2025-04-16 | — | — | EP | disclosed |
| US-12274679-B2 | Substituted alkylphenols as HCN1 antagonists | CORNELL UNIVERSITY (US) | 2025-04-15 | — | — | US | disclosed |
| US-20250115561-A1 | BIPHENYL-SUBSTITUTED EPITHELIAL SODIUM CHANNEL BLOCKING COMPOUNDS | PARION SCIENCES, INC. (US) | 2025-04-10 | — | — | US | disclosed |
| US-20250114448-A1 | SAPONIN-BASED ADJUVANTS AND VACCINES | ASOCIACION CENTRO DE INVESTIG COOPERATIVA EN BIOCIENCIAS CIC BIOGUNE (ES) | 2025-04-10 | — | — | US | disclosed |
| WO-2025075976-A2 | METHYL-BRANCHED LIPOSOMES FOR SUSTAINED DRUG DELIVERY | THE CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2025-04-10 | — | — | WO | disclosed |
| WO-2025076010-A1 | SITE-SELECTIVE CONJUGATION OF A PHARMACEUTICAL AGENT TO AN ANTIBODY USING AN AFFINITY PEPTIDE | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2025-04-10 | — | — | WO | disclosed |
| EP-4532513-A1 | CYCLIC PEPTIDES WITH ANTIBACTERIAL ACTIVITY AGAINST MULTIDRUG RESISTANT (MDR) PATHOGENS | Fundación Privada Instituto De Salud Global Barcelona (ES) | 2025-04-09 | — | — | EP | disclosed |
| US-12268739-B2 | Use of toll-like receptor 2 (TLR-2) agonist for modulating human immune response | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2025-04-08 | — | — | US | disclosed |
| WO-2025072862-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2025-04-03 | — | — | WO | disclosed |
| US-20250109165-A1 | CYCLOPHILIN INHIBITORS AND USES THEREOF | THE BROAD INSTITUTE, INC. (US) | 2025-04-03 | — | — | US | disclosed |
| US-20250109110-A1 | BICYCLIC-SUBSTITUTED EPITHELIAL SODIUM CHANNEL BLOCKING COMPOUNDS | PARION SCIENCES, INC. (US) | 2025-04-03 | — | — | US | disclosed |
| WO-2025072879-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2025-04-03 | — | — | WO | disclosed |
| US-20250108124-A1 | ANTIBODY DRUG CONJUGATES USING MATES TECHNOLOGY FOR DELIVERING CYTOTOXIC AGENTS | BIOHAVEN THERAPEUTICS LTD (US) | 2025-04-03 | — | — | US | disclosed |
| WO-2025066935-A1 | COMPOUNDS, COMPOSITIONS AND METHODS THEREOF | HEPAITECH (BEIJING) BIOPHARMA TECHNOLOGY CO., LTD. (CN) | 2025-04-03 | — | — | WO | disclosed |
| WO-2025072886-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2025-04-03 | — | — | WO | disclosed |
| WO-2025072883-A2 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2025-04-03 | — | — | WO | disclosed |
| WO-2025072881-A2 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2025-04-03 | — | — | WO | disclosed |
| US-12264154-B2 | Compounds and methods of use | TANGO THERAPEUTICS, INC. (US) | 2025-04-01 | — | — | US | disclosed |
| WO-2025064683-A1 | SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS | Interdict Bio, Inc. (US) | 2025-03-27 | — | — | WO | disclosed |
| WO-2025061967-A1 | \"GOOD\" BUFFER-BASED CATIONIC LIPIDS FOR NUCLEIC ACID DELIVERY | SANOFI (FR) | 2025-03-27 | — | — | WO | disclosed |
| US-20250101018-A1 | HETEROARYL COMPOUNDS AND USES THEREOF | APRINOIA THERAPEUTICS LIMITED (CN) | 2025-03-27 | — | — | US | disclosed |
| WO-2025064718-A1 | SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS | Interdict Bio, Inc. (US) | 2025-03-27 | — | — | WO | disclosed |
| EP-4525855-A1 | INTERCALATING SUGAR MOLECULES | Xalud Therapeutics, Inc. (US) | 2025-03-26 | — | — | EP | disclosed |
| US-12258423-B2 | Stapled and stitched polypeptides and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2025-03-25 | — | — | US | disclosed |
| WO-2025059538-A1 | YAP DEGRADERS AS POTENTIAL ANTICANCER DRUGS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2025-03-20 | — | — | WO | disclosed |
| US-20250091989-A1 | SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS | Interdict Bio, Inc. (US) | 2025-03-20 | — | — | US | disclosed |
| US-20250092085-A1 | SAPONIN-BASED ADJUVANTS AND VACCINES | ASOCIACIÓN CENTRO DE INVESTIGACIÓN COOPERATIVA EN BIOCIENCIAS-CIC BIOGUNE (ES) | 2025-03-20 | — | — | US | disclosed |
| US-20250092070-A9 | DEGRADABLE POLYMERS OF A CYCLIC SILYL ETHER AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2025-03-20 | — | — | US | disclosed |
| EP-4522180-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | Amylyx Pharmaceuticals Inc. (US) | 2025-03-19 | — | — | EP | disclosed |
| EP-3889139-B1 | COMPOUNDS FOR TREATING PROLIFERATIVE DISEASES | CHILDRENS MEDICAL CT CORP (US) | 2025-03-19 | — | — | EP | disclosed |
| EP-4522744-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | Wave Life Sciences Ltd. (SG) | 2025-03-19 | — | — | EP | disclosed |
| EP-4522628-A2 | OLIGONUCLEOTIDES HAVING A SYNTHETIC BACKBONE AND SYNTHESIS THEREOF | Adarx Pharmaceuticals, Inc. (US) | 2025-03-19 | — | — | EP | disclosed |
| US-20250084103-A1 | COMPOUNDS, CONJUGATES, AND COMPOSITIONS OF EPIPOLYTHIODIKETOPIPERAZINES AND POLYTHIODIKETOPIPERAZINES AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2025-03-13 | — | — | US | disclosed |
| WO-2025003759-A9 | DIANHYDROHEXITOL BASED IONIZABLE LIPIDS FOR NUCLEIC ACID DELIVERY | SANOFI (FR) | 2025-03-13 | — | — | WO | disclosed |
| WO-2025054431-A1 | BENZO-FUSED HETEROCYCLIC COMPOUNDS AND USES THEREOF | XENON PHARMACEUTICALS INC. (CA) | 2025-03-13 | — | — | WO | disclosed |
| WO-2025054361-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2025-03-13 | — | — | WO | disclosed |
| EP-4519275-A1 | FLUORESCENT DYE FOR PROTEIN OR NUCLEIC ACID LABELING | Quantum-Si Incorporated (US) | 2025-03-12 | — | — | EP | disclosed |
| US-12246021-B2 | Compounds for uses in pharmacological induction of HBF for treatment of sickle cell disease and ß-thalassemia | ACADEMIA SINICA (TW) | 2025-03-11 | — | — | US | disclosed |
| US-20250073351-A1 | IMPROVED COMPOSITIONS FOR DELIVERY OF MRNA | TRANSLATE BIO, INC. | 2025-03-06 | — | — | US | disclosed |
| US-20250066775-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2025-02-27 | — | — | US | disclosed |
| US-20250064938-A1 | IONIZABLE LIPIDS FOR MULTIPLE ORGAN TARGETING | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2025-02-27 | — | — | US | disclosed |
| EP-4511043-A1 | LINCOSAMIDES AND USES THEREOF | President and Fellows of Harvard College (US) | 2025-02-26 | — | — | EP | disclosed |
| WO-2025038920-A1 | HETEROARYL AMINE COMPOUNDS AND USES THEREOF | XENON PHARMACEUTICALS, INC. (CA) | 2025-02-20 | — | — | WO | disclosed |
| WO-2025038970-A1 | MODIFIED OLIGONUCLEOTIDES CONTAINING MULTIPLE OLIGONUCLEOTIDES | ADARX PHARMACEUTICALS, INC. (US) | 2025-02-20 | — | — | WO | disclosed |
| WO-2025038933-A1 | ARYL AMINE COMPOUNDS AND USES THEREOF | XENON PHARMACEUTICALS INC. (CA) | 2025-02-20 | — | — | WO | disclosed |
| WO-2025038960-A1 | OLIGONUCLEOTIDES CONTAINING A LIGAND AT AN INTERNAL POSITION | ADARX PHARMACEUTICALS, INC. (US) | 2025-02-20 | — | — | WO | disclosed |
| WO-2025038673-A1 | BACKBONE CLEAVABLE POLYMETHACRYLATES VIA THIONOLACTONE COMONOEMERS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2025-02-20 | — | — | WO | disclosed |
| WO-2025038930-A1 | AZEPANE AND PYRROLIDINE COMPOUNDS AND USES THEREOF | XENON PHARMACEUTICALS, INC. (CA) | 2025-02-20 | — | — | WO | disclosed |
| WO-2025038963-A1 | OLIGONUCLEOTIDES CONTAINING MULTIPLE LIGANDS AND/OR LIPIDS | ADARX PHARMACEUTICALS, INC. (US) | 2025-02-20 | — | — | WO | disclosed |
| WO-2025038917-A1 | HETEROARYL AMINE COMPOUNDS AND USES THEREOF | XENON PHARMACEUTICALS INC. (CA) | 2025-02-20 | — | — | WO | disclosed |
| US-20250057963-A1 | DISCOVERY OF PIPERLONGUMINE AS A NOVEL E3 LIGASE LIGAND | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2025-02-20 | — | — | US | disclosed |
| EP-4509118-A2 | HIGH-PURITY PEG LIPIDS AND USES THEREOF | ModernaTX, Inc. (US) | 2025-02-19 | — | — | EP | disclosed |
| EP-4507700-A2 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO | Wave Life Sciences Ltd. (SG) | 2025-02-19 | — | — | EP | disclosed |
| EP-4508039-A1 | GOOD\" BUFFER-BASED CATIONIC LIPIDS | Sanofi (FR) | 2025-02-19 | — | — | EP | disclosed |
| US-12227535-B2 | Triterpene saponins, methods of synthesis and uses thereof | SLOAN KETTERING INSTITUTE FOR CANCER RESEARCH | 2025-02-18 | — | — | US | disclosed |
| US-20250049714-A1 | SYNTHESIS OF ESTER, CARBONATE, AND CARBAMATE-DERIVED NOVEL BIODEGRADABLE IONIZABLE LIPIDS FROM METHYL RICINOLEATE OR METHYL 12-HYDROXYSTEARATE AND ITS APPLICATIONS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2025-02-13 | — | — | US | disclosed |
| WO-2025003463-A9 | POLYPROLINE-BASED BLOCK COPOLYMERS | POLYPEPTIDE THERAPEUTIC SOLUTIONS, S.L. (ES) | 2025-02-13 | — | — | WO | disclosed |
| WO-2025034531-A1 | SMALL MOLECULE ALLOSTERIC MODULATOR TO PAC1 RECEPTOR AND USES THEREOF | THE UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE (US) | 2025-02-13 | — | — | WO | disclosed |
| US-20250051778-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2025-02-13 | — | — | US | disclosed |
| US-20250049711-A1 | COMPOSITIONS COMPRISING MODIFIED PHOSPHOLIPIDS AND USES THEREOF | THE CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2025-02-13 | — | — | US | disclosed |
| EP-4504191-A1 | INHIBITING HISTONE DEACETYLASE 6 (HDAC6) | Eikonizo Therapeutics, Inc. (US) | 2025-02-12 | — | — | EP | disclosed |
| EP-4504190-A1 | OXADIAZOLE HDAC6 INHIBITORS AND USES THEREOF | Eikonizo Therapeutics, Inc. (US) | 2025-02-12 | — | — | EP | disclosed |
| EP-4504196-A1 | ALPHA4BETA1/7 INTEGRIN LIGAND CONJUGATED COMPOUNDS AND USES THEREOF | Adarx Pharmaceuticals, Inc. (US) | 2025-02-12 | — | — | EP | disclosed |
| WO-2023198857-A9 | \"GOOD\" BUFFER-BASED CATIONIC LIPIDS | SANOFI (FR) | 2025-02-06 | — | — | WO | disclosed |
| WO-2024178067-A9 | CHIMERIC DEGRADERS OF CYCLIN-DEPENDENT KINASE 9 AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2025-02-06 | — | — | WO | disclosed |
| US-20250041247-A1 | SMALL MOLECULE INHIBITORS OF REPEAT ASSOCIATED NON-AUG (RAN) TRANSLATION AND COMBINATION THERAPIES | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2025-02-06 | — | — | US | disclosed |
| US-20250034443-A1 | HYDROXY/AMINO OXIME-BASED HOT MELT ADHESIVES FOR REWORK, REPAIR, AND RECYCLE | CONAGEN INC. (US) | 2025-01-30 | — | — | US | disclosed |
| US-20250032465-A1 | METHODS OF TREATING CNS DISORDERS | HANGZHOU HIGHLIGHTLL PHARMACEUTICAL CO LTD (CN) | 2025-01-30 | — | — | US | disclosed |
| WO-2025024605-A1 | REV-ERB ANTAGONISTS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2025-01-30 | — | — | WO | disclosed |
| US-20250034170-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | VANQUA BIO, INC. (US) | 2025-01-30 | — | — | US | disclosed |
| WO-2025024550-A1 | REV-ERB ANTAGONISTS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2025-01-30 | — | — | WO | disclosed |
| US-12209076-B2 | Imidazolyl kinase inhibitors and uses thereof | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2025-01-28 | — | — | US | disclosed |
| WO-2025019599-A2 | BIFUNCTIONAL KINASE BINDING COMPOUNDS AND USES THEREOF | PHOTYS THERAPEUTICS, INC. (US) | 2025-01-23 | — | — | WO | disclosed |
| US-20250025550-A1 | ADJUVANT COMPOUNDS AND FORMULATIONS | ADJUVANCE TECH INC (US) | 2025-01-23 | — | — | US | disclosed |
| US-20250025564-A1 | SIMPLE CHEMICAL APPROACHES TO INTRODUCE 2,6-DIAMINOPURINE AND 2-AMINOADENINE CONJUGATES INTO OLIGONUCLEOTIDES | ALNYLAM PHARMACEUTICALS, INC. (US) | 2025-01-23 | — | — | US | disclosed |
| EP-4494698-A2 | INHIBITORS OF PLASMA KALLIKREIN AND USES THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2025-01-22 | — | — | EP | disclosed |
| US-20250019375-A1 | BENZOTHIAZOLE DYES | DETECT INC (US) | 2025-01-16 | — | — | US | disclosed |
| US-12195475-B2 | Compounds for the treatment of kinase-dependent disorders | EXELIXIS, INC. (US) | 2025-01-14 | — | — | US | disclosed |
| EP-4486336-A2 | CB1 LIGAND CONJUGATED COMPOUNDS AND USES THEREOF | Adarx Pharmaceuticals, Inc. (US) | 2025-01-08 | — | — | EP | disclosed |
| US-12187736-B2 | Selective estrogen receptor degraders and uses thereof | INVENTISBIO LLC (US) | 2025-01-07 | — | — | US | disclosed |
| US-12186396-B2 | Branched multi-functional macromonomers and related polymers and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2025-01-07 | — | — | US | disclosed |
| US-12187755-B2 | Minimal saponin analogues, synthesis and use thereof | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2025-01-07 | — | — | US | disclosed |
| US-12187701-B2 | Taire family kinase inhibitors and uses thereof | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2025-01-07 | — | — | US | disclosed |
| WO-2025006617-A2 | AGENTS FOR TREATING DISORDERS INVOLVING RYANODINE RECEPTORS | ARMGO PHARMA, INC. (US) | 2025-01-02 | — | — | WO | disclosed |
| US-20250001002-A1 | COMPOSITIONS FOR DELIVERY OF MRNA | TRANSLATE BIO, INC. | 2025-01-02 | — | — | US | disclosed |
| WO-2025006929-A2 | BENZOTHIAZOLE DYES | DETECT, INC. (US) | 2025-01-02 | — | — | WO | disclosed |
| WO-2025003755-A1 | HELPER LIPIDS FOR NUCLEIC ACID DELIVERY | SANOFI (FR) | 2025-01-02 | — | — | WO | disclosed |
| US-20250002450-A1 | CATIONIC STEROID COMPOUNDS, METHOD OF OBTAINING THEREOF, FORMULATIONS COMPRISING THEREOF AND THEIR USES | UNIVERSIDADE DO PORTO (PT) | 2025-01-02 | — | — | US | disclosed |
| US-20250002768-A1 | PHENOL-BASED HOT MELT ADHESIVES FOR REWORK, REPAIR AND RECYCLE | CONAGEN INC. (US) | 2025-01-02 | — | — | US | disclosed |
| WO-2025003463-A1 | POLYPROLINE-BASED BLOCK COPOLYMERS | POLYPEPTIDE THERAPEUTIC SOLUTIONS, S.L. (ES) | 2025-01-02 | — | — | WO | disclosed |
| US-20250002637-A1 | OXIME-BASED HOT MELT ADHESIVES FOR REWORK, REPAIR, AND RECYCLE | CONAGEN INC. (US) | 2025-01-02 | — | — | US | disclosed |
| WO-2025003759-A1 | DIANHYDROHEXITOL BASED IONIZABLE LIPIDS FOR NUCLEIC ACID DELIVERY | SANOFI (FR) | 2025-01-02 | — | — | WO | disclosed |
| EP-4482825-A2 | INHIBITORS OF DDR1 AND DDR2 FOR THE TREATMENT OF ARTHRITIS | President and Fellows of Harvard College (US) | 2025-01-01 | — | — | EP | disclosed |
| US-12180228-B2 | Compounds, conjugates, and compositions of epipolythiodiketopiperazines and polythiodiketopiperazines and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2024-12-31 | — | — | US | disclosed |
| US-12180472-B2 | Chiral design | WAVE LIFE SCIENCES LTD. (SG) | 2024-12-31 | — | — | US | disclosed |
| US-20240425633-A1 | FUNCTIONAL OLIGOMERS AND FUNCTIONAL POLYMERS INCLUDING HYDROXYLATED POLYMERS AND CONJUGATES THEREOF AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2024-12-26 | — | — | US | disclosed |
| US-20240423894-A1 | CLEAVABLE COMONOMER STRATEGY FOR ACCELERATING REMOVAL OF GEL NAIL POLISH | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2024-12-26 | — | — | US | disclosed |
| WO-2024256457-A1 | TRICINE AND CITRIC ACID-BASED CATIONIC LIPIDS WITH AROMATIC HEAD GROUPS | SANOFI (FR) | 2024-12-19 | — | — | WO | disclosed |
| US-20240417372-A1 | ESTERS OF A RETINOID AND BAKUCHIOL AND PREPARATIONS THEREOF | CONAGEN INC. (US) | 2024-12-19 | — | — | US | disclosed |
| WO-2024256453-A1 | STEROL-BASED CATIONIC LIPIDS WITH AROMATIC HEAD GROUPS | SANOFI (FR) | 2024-12-19 | — | — | WO | disclosed |
| WO-2024259178-A1 | GLYCOGEN SYNTHASE KINASE 3 INHIBITORS AND USES THEREOF | THE BROAD INSTITUTE, INC. (US) | 2024-12-19 | — | — | WO | disclosed |
| WO-2024259190-A2 | 5'-MODIFIED MONOMERS, OLIGONUCLEOTIDES AND DOUBLE-STRANDED RNAS | ALNYLAM PHARMACEUTICALS, INC. (US) | 2024-12-19 | — | — | WO | disclosed |
| WO-2024259328-A1 | INHIBITORS OF RIPK2 AND USES THEREOF | ODYSSEY THERAPEUTICS, INC. (US) | 2024-12-19 | — | — | WO | disclosed |
| WO-2024259383-A2 | ION CHANNEL BINDERS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2024-12-19 | — | — | WO | disclosed |
| US-12168663-B2 | Inhibitors of cyclin-dependent kinase 7 (CDK7) | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2024-12-17 | — | — | US | disclosed |
| WO-2024254017-A2 | STAPLED PEPTIDES AND METHODS THEREOF | FOG PHARMACEUTICALS, INC. (US) | 2024-12-12 | — | — | WO | disclosed |
| EP-2892509-B1 | BOLAAMPHIPHILIC COMPOUNDS, COMPOSITIONS AND USES THEREOF | LAUREN SCIENCES LLC (US) | 2024-12-11 | — | — | EP | disclosed |
| EP-3308822-B1 | A UROLOGICAL DEVICE | COLOPLAST AS (DK) | 2024-12-11 | — | — | EP | disclosed |
| US-20240398720-A1 | CATIONIC POLYMERS | TRANSLATE BIO, INC. | 2024-12-05 | — | — | US | disclosed |
| WO-2024249763-A2 | PRMT5 SYNTHETIC LETHAL INHIBITORS TARGETING MTAP DELETED CANCERS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2024-12-05 | — | — | WO | disclosed |
| WO-2024249931-A1 | PRMT5 INHIBITORS TARGETING MTAP DELETED CANCERS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2024-12-05 | — | — | WO | disclosed |
| EP-4469445-A1 | COMPOUNDS AND METHODS OF USE | Tango Therapeutics, Inc. (US) | 2024-12-04 | — | — | EP | disclosed |
| EP-4469441-A1 | BIPHENYL-SUBSTITUTED EPITHELIAL SODIUM CHANNEL BLOCKING COMPOUNDS | Parion Sciences, Inc. (US) | 2024-12-04 | — | — | EP | disclosed |
| EP-4469447-A1 | COMPOUNDS AND METHODS OF USE | Tango Therapeutics, Inc. (US) | 2024-12-04 | — | — | EP | disclosed |
| EP-4469438-A1 | COMPOUNDS AND METHODS OF USE | Tango Therapeutics, Inc. (US) | 2024-12-04 | — | — | EP | disclosed |
| EP-4469455-A1 | COMPOUNDS AND METHODS OF USE | Tango Therapeutics, Inc. (US) | 2024-12-04 | — | — | EP | disclosed |
| US-20240391956-A1 | STAPLED PEPTIDES AND METHODS THEREOF | PARABILIS MEDICINES, INC. | 2024-11-28 | — | — | US | disclosed |
| WO-2024243015-A2 | COMPOUNDS FOR TREATING HEREDITARY SPASTIC PARAPLEGIA | THE CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2024-11-28 | — | — | WO | disclosed |
| EP-4466278-A1 | SAPONIN-BASED ADJUVANTS AND VACCINES | Asociación Centro de Investigación Cooperativa en Biociencias - CIC bioGUNE (ES) | 2024-11-27 | — | — | EP | disclosed |
| US-12152016-B2 | Aryl hydrocarbon receptor modulators and uses thereof | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. (US) | 2024-11-26 | — | — | US | disclosed |
| US-12151029-B2 | PEG lipids and uses thereof | MODERNATX, INC. (US) | 2024-11-26 | — | — | US | disclosed |
| WO-2024238369-A1 | DECREASING THE INTRINSICALLY DISORDERED PROTEIN ALPHA-SYNUCLEIN'S LEVELS BY TARGETING ITS STRUCTURED MRNA WITH A RIBONUCLEASE TARGETING CHIMERA | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2024-11-21 | — | — | WO | disclosed |
| US-20240383940-A1 | SYNTHESIS OF TRINUCLEOTIDE AND TETRANUCLEOTIDE CAPS FOR MRNA PRODUCTION | Moderna TX, Inc. (US) | 2024-11-21 | — | — | US | disclosed |
| WO-2024238396-A1 | NMDA LIGAND CONJUGATED COMPOUNDS AND USES THEREOF | ADARX PHARMACEUTICALS, INC. (US) | 2024-11-21 | — | — | WO | disclosed |
| US-20240383847-A1 | BIOMOLECULE-POLYMER-PHARMACEUTICAL AGENT CONJUGATES FOR DELIVERING THE PHARMACEUTICAL AGENT | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2024-11-21 | — | — | US | disclosed |
| WO-2024238359-A2 | TARGETING RNAS ASSOCIATED WITH TAUOPATHIES WITH SMALL MOLECULES | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2024-11-21 | — | — | WO | disclosed |
| EP-3548096-B1 | INHIBITOR-FUNCTIONALIZED ULTRASMALL NANOPARTICLES AND METHODS THEREOF | MEMORIAL SLOAN KETTERING CANCER CENTER (US) | 2024-11-20 | — | — | EP | disclosed |
| US-12145912-B2 | Ionizable lipidoids and their uses | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2024-11-19 | — | — | US | disclosed |
| WO-2024233665-A1 | COMPOUNDS AND THEIR USE AGAINST CANCER | TANGO THERAPEUTICS, INC. (US) | 2024-11-14 | — | — | WO | disclosed |
| US-20240376074-A1 | NAMPT INHIBITORS AND USES THEREOF | REMEDY PLAN, INC. (US) | 2024-11-14 | — | — | US | disclosed |
| WO-2024233624-A1 | OLIGONUCLEOTIDE SYNTHESIS USING CYCLIC-PHOSPHOROUS NUCLEOSIDES | ELI LILLY AND COMPANY (US) | 2024-11-14 | — | — | WO | disclosed |
| WO-2024233839-A1 | SMALL MOLECULE INHIBITORS OF GLUTAMINASE | LEAL THERAPEUTICS, INC. (US) | 2024-11-14 | — | — | WO | disclosed |
| US-20240376145-A9 | STEROIDAL COMPOUND DERIVATIVES AS THERAPEUTIC AGENTS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2024-11-14 | — | — | US | disclosed |
| US-20240376504-A1 | ENZYMATIC SYNTHESIS OF MYCOSPORINE-LIKE AMINO ACIDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2024-11-14 | — | — | US | disclosed |
| WO-2024233605-A1 | COMPOUNDS AND THEIR USE AGAINST CANCER | TANGO THERAPEUTICS, INC. (US) | 2024-11-14 | — | — | WO | disclosed |
| US-20240376133-A9 | CROSSLINKING COMONOMERS FOR HIGH PERFORMANCE DEGRADABLE THERMOSETS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2024-11-14 | — | — | US | disclosed |
| US-20240368132-A1 | ROCK2 INHIBITORS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2024-11-07 | — | — | US | disclosed |
| US-20240366529-A1 | SUBSTITUTED ALKYLPHENOLS AS HCN1 ANTAGONISTS | CORNELL UNIVERSITY (US) | 2024-11-07 | — | — | US | disclosed |
| US-20240368591-A1 | OLIGOMERIC COMPOUND FOR DYSTROPHIN RESCUE IN DMD PATIENTS THROUGHOUT SKIPPING OF EXON-51 | SQY THERAPEUTICS (FR) | 2024-11-07 | — | — | US | disclosed |
| EP-3257887-B1 | POLYCARBONATE POLYOL COMPOSITIONS AND METHODS | SAUDI ARAMCO TECH CO (SA) | 2024-11-06 | — | — | EP | disclosed |
| US-20240360103-A1 | COMPLEMENT INHIBITION | SIXTH STREET LENDING PARTNERS | 2024-10-31 | — | — | US | disclosed |
| US-20240360132-A9 | TRICYCLIC KINASE INHIBITORS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2024-10-31 | — | — | US | disclosed |
| US-20240360179-A1 | STAPLED PEPTIDES AND METHODS THEREOF | PARABILIS MEDICINES, INC. | 2024-10-31 | — | — | US | disclosed |
| US-20240360104-A1 | TRANSCRIPTIONAL ENHANCED ASSOCIATED DOMAIN (TEAD) TRANSCRIPTION FACTOR INHIBITORS AND USES THEREOF | DANA FARBER CANCER INST INC (US) | 2024-10-31 | — | — | US | disclosed |
| US-20240360076-A1 | NONIONIC SURFACTANTS | DETECT INC (US) | 2024-10-31 | — | — | US | disclosed |
| EP-4452933-A1 | BIOMOLECULE-POLYMER-PHARMACEUTICAL AGENT CONJUGATES FOR DELIVERING THE PHARMACEUTICAL AGENT | Massachusetts Institute of Technology (US) | 2024-10-30 | — | — | EP | disclosed |
| US-12128018-B2 | Combination of a selective histone deacetylase 3 (HDAC3) inhibitor and an immunotherapy agent for the treatment of cancer | KDAc Therapeutics, Inc. (US) | 2024-10-29 | — | — | US | disclosed |
| US-12129275-B2 | Neuroactive steroids, compositions, and uses thereof | SAGE THERAPEUTICS, INC. (US) | 2024-10-29 | — | — | US | disclosed |
| WO-2024217484-A1 | COMPOUNDS, COMPOSITIONS AND METHODS THEREOF | HEPAITECH (BEIJING) BIOPHARMA TECHNOLOGY CO., LTD. (CN) | 2024-10-24 | — | — | WO | disclosed |
| WO-2024220676-A1 | MRNA DEGRADERS AND METHODS OF USE THEREOF | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2024-10-24 | — | — | WO | disclosed |
| WO-2024218268-A1 | SAPONIN DERIVATIVES AS ADJUVANTS AND PHOTOAFFINITY PROBES | ASOCIACIÓN CENTRO DE INVESTIGACIÓN COOPERATIVA EN BIOCIENCIAS-CIC BIOGUNE (ES) | 2024-10-24 | — | — | WO | disclosed |
| WO-2024220852-A2 | TEAD CORE INHIBITORS FOR CANCER THERAPEUTICS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2024-10-24 | — | — | WO | disclosed |
| EP-3661922-B1 | INHIBITORS OF PLASMA KALLIKREIN AND USES THEREOF | TAKEDA PHARMACEUTICALS CO (JP) | 2024-10-23 | — | — | EP | disclosed |
| US-12121521-B2 | Uses of salt-inducible kinase (SIK) inhibitors for treating osteoporosis | THE GENERAL HOSPITAL CORPORATION (US) | 2024-10-22 | — | — | US | disclosed |
| US-20240343752-A1 | NOVEL BICYCLIC NUCLEOSIDES AND OLIGOMERS PREPARED THEREFROM | UNIV BERN (CH) | 2024-10-17 | — | — | US | disclosed |
| US-20240343760-A1 | PEPTIDES FOR CELL-TYPE SPECIFIC TARGETING OF THE RETINA | OREGON STATE UNIVERSITY (OR) | 2024-10-17 | — | — | US | disclosed |
| EP-4444422-A1 | CATIONIC STEROID COMPOUNDS, METHOD OF OBTAINING THEREOF, FORMULATIONS COMPRISING THEREOF AND THEIR USES | Universidade Do Porto (PT) | 2024-10-16 | — | — | EP | disclosed |
| EP-4444274-A1 | COMPOSITIONS COMPRISING MODIFIED PHOSPHOLIPIDS AND USES THEREOF | The Children's Medical Center Corporation (US) | 2024-10-16 | — | — | EP | disclosed |
| US-12116364-B2 | Heteroaryl compounds and uses thereof | APRINOIA THERAPEUTICS INC. (CN) | 2024-10-15 | — | — | US | disclosed |
| US-20240335555-A1 | TECHNOLOGIES FOR PREVENTING OR TREATING INFECTIONS | BIOHAVEN THERAPEUTICS LTD. | 2024-10-10 | — | — | US | disclosed |
| EP-4440622-A1 | SAPONIN-BASED ADJUVANTS AND VACCINES | Asociación Centro de Investigación Cooperativa en Biociencias - CIC bioGUNE (ES) | 2024-10-09 | — | — | EP | disclosed |
| EP-4441120-A1 | POLY(?-AMINO ESTER) MICROPARTICLES FOR MICRONUTRIENT FORTIFICATION | Massachusetts Institute of Technology (US) | 2024-10-09 | — | — | EP | disclosed |
| EP-4440560-A1 | SMALL MOLECULE INHIBITORS OF REPEAT ASSOCIATED NON-AUG (RAN) TRANSLATION AND COMBINATION THERAPIES | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2024-10-09 | — | — | EP | disclosed |
| US-12109207-B2 | Methods of using 4(1H)-quinolone derivatives | ACADEMIA SINICA (TW) | 2024-10-08 | — | — | US | disclosed |
| US-20240327443-A1 | TRITERPENE SAPONIN ANALOGUES | ADJUVANCE TECHNOLOGIES, INC. (US) | 2024-10-03 | — | — | US | disclosed |
| US-20240325575-A1 | LABELING OF ANTIBODIES | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2024-10-03 | — | — | US | disclosed |
| WO-2024206939-A2 | SARS-COV-2 ENTRY INHIBITORS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2024-10-03 | — | — | WO | disclosed |
| EP-3853305-B1 | HIGH-PURITY PEG LIPIDS AND USES THEREOF | MODERNATX INC (US) | 2024-10-02 | — | — | EP | disclosed |
| US-20240316216-A1 | LIPID NANOPARTICLES FOR DRUG DELIVERY TO MICROGLIA IN THE BRAIN | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2024-09-26 | — | — | US | disclosed |
| WO-2024192530-A1 | VERDAZYL COMPOUNDS AS CONTRAST AGENTS FOR MAGNETIC RESONANCE IMAGING OF KIDNEYS | YELLOWBIRD DIAGNOSTICS INC. (CA) | 2024-09-26 | — | — | WO | disclosed |
| EP-4433475-A1 | POLYCYCLIC COMPOUNDS AND METHODS THEREOF | Hepaitech (Beijing) Biopharma Technology Co., Ltd. (CN) | 2024-09-25 | — | — | EP | disclosed |
| US-12098154-B2 | Inhibitors of cyclin-dependent kinases | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2024-09-24 | — | — | US | disclosed |
| US-20240307401-A1 | TREATMENT OF JAK-INHIBITION-RESPONSIVE DISORDERS WITH PRODRUGS OF JAK INHIBITORS | SUN PHARMACEUTICAL INDUSTRIES, INC. | 2024-09-19 | — | — | US | disclosed |
| US-20240309014-A1 | MACROCYCLIC COMPOUNDS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2024-09-19 | — | — | US | disclosed |
| US-20240309049-A1 | SYNTHETIC DNA BINDING DOMAIN PEPTIDES AND USES THEREOF | THE UNIVERSITY OF CHICAGO (US) | 2024-09-19 | — | — | US | disclosed |
| EP-4429674-A1 | ADJUVANT COMPOUNDS AND FORMULATIONS | Adjuvance Technologies, Inc. (US) | 2024-09-18 | — | — | EP | disclosed |
| WO-2024187020-A1 | BIFUNCTIONAL KINASE BINDING COMPOUNDS AND USES THEREOF | PHOTYS THERAPEUTICS, INC. (US) | 2024-09-12 | — | — | WO | disclosed |
| US-20240301430-A1 | CHEMICALLY MODIFIED OLIGONUCLEOTIDES | PHIO PHARMACEUTICALS CORP. (US) | 2024-09-12 | — | — | US | disclosed |
| US-20240300972-A1 | THIOPHENE-BASED LIPIDS | OREGON STATE UNIVERSITY (US) | 2024-09-12 | — | — | US | disclosed |
| US-12083186-B2 | Methods for assembling scavenging particles | NANOTICS, LLC (US) | 2024-09-10 | — | — | US | disclosed |
| US-12084415-B2 | Biomolecule-polymer-pharmaceutical agent conjugates for delivering the pharmaceutical agent | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2024-09-10 | — | — | US | disclosed |
| WO-2024182555-A1 | CYCLIN DEPENDENT KINASE DEGRADERS AND METHODS OF USE THEREOF | DIFFERENTIATED THERAPEUTICS, INC. (US) | 2024-09-06 | — | — | WO | disclosed |
| US-20240293319-A1 | Lipid Formulations for Delivery of Messenger RNA | TRANSLATE BIO, INC. (US) | 2024-09-05 | — | — | US | disclosed |
| US-20240294555-A1 | DEGRADABLE POLYMERS OF A CYCLIC SILYL ETHER AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2024-09-05 | — | — | US | disclosed |
| US-20240294573-A1 | CONSTRAINED PEPTIDES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2024-09-05 | — | — | US | disclosed |
| US-20240294957-A1 | ENZYMATIC SYNTHESIS OF KAVALACTONES AND FLAVOKAVAINS | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2024-09-05 | — | — | US | disclosed |
| EP-4422645-A2 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | Wave Life Sciences Ltd. (SG) | 2024-09-04 | — | — | EP | disclosed |
| WO-2024174995-A1 | COMPOUNDS, COMPOSITIONS AND METHODS THEREOF | HEPAITECH (BEIJING) BIOPHARMA TECHNOLOGY CO., LTD. (CN) | 2024-08-29 | — | — | WO | disclosed |
| WO-2024178067-A1 | CHIMERIC DEGRADERS OF CYCLIN-DEPENDENT KINASE 9 AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2024-08-29 | — | — | WO | disclosed |
| EP-4419101-A1 | METHODS OF TREATING CNS DISORDERS | Hangzhou Highlightll Pharmaceutical Co., Ltd. (CN) | 2024-08-28 | — | — | EP | disclosed |
| EP-4419513-A1 | ANTITUMORAL COMPOUNDS | Pharma Mar S.A. (ES) | 2024-08-28 | — | — | EP | disclosed |
| EP-4419536-A1 | OLIGONUCLEOTIDES WITH 2'-DEOXY-2'-F-2'-C-METHYL NUCLEOTIDES | Alnylam Pharmaceuticals, Inc. (US) | 2024-08-28 | — | — | EP | disclosed |
| US-12071436-B2 | Anti-parasitic compounds and uses thereof | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) | 2024-08-27 | — | — | US | disclosed |
| WO-2024173766-A1 | CYCLIN DEPENDENT KINASE DEGRADERS AND METHODS OF USE THEREOF | DIFFERENTIATED THERAPEUTICS, INC. (US) | 2024-08-22 | — | — | WO | disclosed |
| WO-2024173412-A2 | CYCLIN DEPENDENT KINASE DEGRADERS AND METHODS OF USE THEREOF | DIFFERENTIATED THERAPEUTICS, INC. (US) | 2024-08-22 | — | — | WO | disclosed |
| US-20240279466-A1 | AN AMINOSQUARAMIDE POLYMER | UNIVERSITAT DE LES ILLES BALEARS (ES) | 2024-08-22 | — | — | US | disclosed |
| US-20240279219-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. | 2024-08-22 | — | — | US | disclosed |
| US-20240279658-A1 | DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO | WAVE LIFE SCIENCES LTD. (SG) | 2024-08-22 | — | — | US | disclosed |
| EP-4416152-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | Vanqua Bio, Inc. (US) | 2024-08-21 | — | — | EP | disclosed |
| EP-4415706-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | Vanqua Bio, Inc. (US) | 2024-08-21 | — | — | EP | disclosed |
| US-20240270898-A1 | LATENT-FLUORIDE CONTAINING POLYMERS FOR TRIGGERED DEGRADATION | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2024-08-15 | — | — | US | disclosed |
| US-20240269319-A1 | METHODS FOR ASSEMBLING SCAVENGING PARTICLES | NANOTICS, LLC | 2024-08-15 | — | — | US | disclosed |
| US-20240269093-A1 | USE OF METFORMIN AND ANALOGS THEREOF TO REDUCE RAN PROTEIN LEVELS IN THE TREATMENT OF NEUROLOGICAL DISORDERS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2024-08-15 | — | — | US | disclosed |
| US-20240270707-A1 | \"Good\" buffer-based cationic lipids | TRANSLATE BIO, INC. (US) | 2024-08-15 | — | — | US | disclosed |
| WO-2024168123-A1 | SYNTHESIS OF CORE 2 O-SIALYL LEWIS-X POLYSACCHARIDES | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. (US) | 2024-08-15 | — | — | WO | disclosed |
| US-12060334-B2 | 3-substituted phenazine derivatives as antimicrobial agents | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2024-08-13 | — | — | US | disclosed |
| US-20240262851-A1 | CYCLOPROPENE PHOSPHORAMIDITES AND CONJUGATES THEREOF | Quantum-Si Incorporated (US) | 2024-08-08 | — | — | US | disclosed |
| WO-2024163962-A1 | 3-((1,1-DIOXIDO-2,3,4,5-TETRAHYDROBENZO[F][1,2,5]THIADIAZEPIN-8-YL)OXY)-2-FLUOROACRYLIC ACID DERIVATIVES AS SODIUM TAUROCHOLATE CO-TRANSPORTING POLYPEPTIDE (NTCP) INHIBITORS FOR THE TREATMENT OF CHOLESTASIS | Hemoshear Therapeutics, Inc. (US) | 2024-08-08 | — | — | WO | disclosed |
| WO-2024163762-A2 | SIX MEMBERED RING CONTAINING OLIGOMERS | ALNYLAM PHARMACEUTICALS, INC. (US) | 2024-08-08 | — | — | WO | disclosed |
| US-20240262832-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | VANQUA BIO, INC. (US) | 2024-08-08 | — | — | US | disclosed |
| US-20240263196-A1 | Lipid Compositions and Methods for Delivery to Immune Cells | Life Technologies Corporation | 2024-08-08 | — | — | US | disclosed |
| EP-4408941-A1 | ANTIFOULING COMPOUND, METHOD AND USES THEREOF | Universidade Do Porto (PT) | 2024-08-07 | — | — | EP | disclosed |
| US-12054570-B2 | Functional oligomers and functional polymers including hydroxylated polymers and conjugates thereof and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2024-08-06 | — | — | US | disclosed |
| US-12053465-B2 | KCC2 expression enhancing compounds and uses thereof | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2024-08-06 | — | — | US | disclosed |
| EP-4404942-A2 | COMPOSITIONS FOR EDITING MECP2 TRANSCRIPTS AND METHODS THEREOF | Wave Life Sciences Ltd. (SG) | 2024-07-31 | — | — | EP | disclosed |
| EP-4405475-A1 | DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO | Wave Life Sciences Ltd. (SG) | 2024-07-31 | — | — | EP | disclosed |
| US-12048753-B2 | Labeling of antibodies | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2024-07-30 | — | — | US | disclosed |
| US-20240246952-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | VANQUA BIO, INC. (US) | 2024-07-25 | — | — | US | disclosed |
| US-20240246943-A1 | MULTIFACETED APPROACH TO NOVEL INTERLEUKIN-6 INHIBITORS | University of Florida Research Fooundation, Incorporated (US) | 2024-07-25 | — | — | US | disclosed |
| US-20240245787-A1 | E3 LIGASE BINDERS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2024-07-25 | — | — | US | disclosed |
| US-20240245695-A1 | USES OF PYRIMIDOPYRIMIDINONES AS SIK INHIBITORS | THE GENERAL HOSPITAL CORPORATION (US) | 2024-07-25 | — | — | US | disclosed |
| US-20240246899-A1 | PROCESSES FOR THE PREPARATION OF (S)-TERT-BUTYL 4,5-DIAMINO-5-OXOPENTANOATE | CELGENE CORPORATION | 2024-07-25 | — | — | US | disclosed |
| EP-4403560-A2 | MACROCYCLIC COMPOUNDS AND USES THEREOF | President And Fellows Of Harvard College (US) | 2024-07-24 | — | — | EP | disclosed |
| US-12042513-B2 | Proteolysis targeting chimeric molecules (PROTACs) with functional handles and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2024-07-23 | — | — | US | disclosed |
| US-20240239774-A1 | SOLUBLE ADENYLYL CYCLASE (SAC) INHIBITORS AND USES THEREOF | CORNELL UNIVERSITY (US) | 2024-07-18 | — | — | US | disclosed |
| WO-2024151519-A2 | PPARG MODULATORS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATIN, INCORPORATED (US) | 2024-07-18 | — | — | WO | disclosed |
| US-20240238321-A1 | MODIFIED OLIGOMERIC COMPOUNDS COMPRISING TRICYCLO-DNA NUCLEOSIDES AND USES THEREOF | SYNTHENA AG (CH) | 2024-07-18 | — | — | US | disclosed |
| US-12037355-B2 | Triterpene saponin analogues | ADJUVANCE TECHNOLOGIES, INC. (US) | 2024-07-16 | — | — | US | disclosed |
| US-20240228475-A1 | PROCESSES FOR THE PREPARATION OF (S)-2-(2,6-DIOXOPIPERIDIN-3-YL)-4-((2-FLUORO-4-((3-MORPHOLINOAZETIDIN-1-YL)METHYL)BENZYL)AMINO)ISOINDOLINE-1,3-DIONE | CELGENE CORPORATION | 2024-07-11 | — | — | US | disclosed |
| US-20240228671-A1 | POLYPEPTIDYL LINKERS | Quantum-Si Incorporated (US) | 2024-07-11 | — | — | US | disclosed |
| US-20240226302-A1 | BIODEGRADABLE LIPIDS AND FORMULATIONS FOR INTRAMUSCULAR, IN VITRO, AND EX VIVO TRANSFECTION OF MRNA | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2024-07-11 | — | — | US | disclosed |
| US-20240229026-A1 | CHIRAL CONTROL | WAVE LIFE SCIENCES LTD. (SG) | 2024-07-11 | — | — | US | disclosed |
| WO-2024147060-A1 | NOVEL IONIZABLE LIPID COMPOUNDS FOR NUCLEIC ACID DELIVERY | CELON PHARMA S.A. (PL) | 2024-07-11 | — | — | WO | disclosed |
| WO-2024148274-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |
| US-20240228478-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. | 2024-07-11 | — | — | US | disclosed |
| EP-4396354-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | Wave Life Sciences Ltd. (SG) | 2024-07-10 | — | — | EP | disclosed |
| US-12030980-B2 | Reprocessable compositions | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2024-07-09 | — | — | US | disclosed |
| US-12030888-B2 | Himastatin derivatives, and processes of preparation thereof, and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2024-07-09 | — | — | US | disclosed |
| WO-2024140431-A1 | COMPOUNDS COMPRISING HETEROARYL RINGS AND COMPOSITIONS AND METHODS THEREOF | IONGEN THERAPEUTICS CO., LTD. (CN) | 2024-07-04 | — | — | WO | disclosed |
| WO-2024145435-A2 | LIPID COMPOSITIONS AND METHODS FOR DELIVERY TO IMMUNE CELLS | Life Technologies Corporation (US) | 2024-07-04 | — | — | WO | disclosed |
| US-RE50030-E1 | Methods to treat lymphoplasmacytic lymphoma | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2024-07-02 | — | — | US | disclosed |
| WO-2024133853-A1 | BIS-ESTER AND AMIDE CATIONIC LIPIDS | SANOFI (FR) | 2024-06-27 | — | — | WO | disclosed |
| US-20240199602-A1 | INHIBITORS OF PLASMA KALLIKREIN AND USES THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2024-06-20 | — | — | US | disclosed |
| US-20240199614-A1 | MACROCYCLIC EGFR INHIBITORS FOR THE TREATMENT OF CANCER | THESEUS PHARMACEUTICALS, INC. (US) | 2024-06-20 | — | — | US | disclosed |
| WO-2024130218-A1 | STAPLED PEPTIDES AND METHODS THEREOF | FOG PHARMACEUTICALS, INC. (US) | 2024-06-20 | — | — | WO | disclosed |
| WO-2023168066-A9 | OXIME-BASED HOT MELT ADHESIVES FOR REWORK, REPAIR AND RECYCLE | CONAGEN INC. (US) | 2024-06-20 | — | — | WO | disclosed |
| WO-2024130217-A1 | STAPLED PEPTIDES AND METHODS THEREOF | FOG PHARMACEUTICALS, INC. (US) | 2024-06-20 | — | — | WO | disclosed |
| EP-4384173-A1 | TREATMENT OF JAK-INHIBITION-RESPONSIVE DISORDERS WITH PRODRUGS OF JAK INHIBITORS | SUN PHARMACEUTICAL INDUSTRIES, INC. (US) | 2024-06-19 | — | — | EP | disclosed |
| WO-2024123978-A1 | IONIZABLE LIPIDS WITH MALONATE TAILS | MODERNATX, INC. (US) | 2024-06-13 | — | — | WO | disclosed |
| US-20240182426-A1 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | Epizyme, Inc. | 2024-06-06 | — | — | US | disclosed |
| US-20240182481-A1 | PYRROLO[3,2-D]PYRIMIDINE COMPOUNDS AND METHODS OF USE IN THE TREATMENT OF CANCER | TANGO THERAPEUTICS, INC. | 2024-06-06 | — | — | US | disclosed |
| US-20240180945-A1 | COMPOUNDS AND PHARMACEUTICAL USES THEREOF | SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) | 2024-06-06 | — | — | US | disclosed |
| US-20240181067-A1 | TARGETED BIFUNCTIONAL DEGRADERS AND METHODS USING SAME | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2024-06-06 | — | — | US | disclosed |
| WO-2024119140-A1 | CLEAVABLE COMONOMER STRATEGY FOR ACCELERATING REMOVAL OF GEL NAIL POLISH | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2024-06-06 | — | — | WO | disclosed |
| EP-4377306-A1 | ROCK2 INHIBITORS AND USES THEREOF | President and Fellows of Harvard College (US) | 2024-06-05 | — | — | EP | disclosed |
| US-11999727-B2 | Compounds and methods of use | TANGO THERAPEUTICS, INC. (US) | 2024-06-04 | — | — | US | disclosed |
| US-20240174637-A1 | DEGRADERS OF GRK2 AND USES THEREOF | PIIZZI GRAZIA (US) | 2024-05-30 | — | — | US | disclosed |
| WO-2024108774-A1 | METAL-CATALYZED DOUBLE HYDROBORATION OF NITROGEN HETEROCYCLICS | GUANGDONG TECHNION-ISRAEL INSTITUTE OF TECHNOLOGY (CN) | 2024-05-30 | — | — | WO | disclosed |
| US-20240174616-A1 | HDAC6 INHIBITORS AND USES THEREOF | EIKONIZO THERAPEUTICS, INC. (US) | 2024-05-30 | — | — | US | disclosed |
| US-20240175016-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2024-05-30 | — | — | US | disclosed |
| WO-2024112854-A1 | INHIBITORS OF RIPK2 AND MEDICAL USES THEREOF | ODYSSEY THERAPEUTICS, INC. (US) | 2024-05-30 | — | — | WO | disclosed |
| US-20240166666-A1 | ANTITUMORAL COMPOUNDS | PHARMA MAR SA (ES) | 2024-05-23 | — | — | US | disclosed |
| EP-4370136-A2 | SIMPLE CHEMICAL APPROACHES TO INTRODUCE 2,6-DIAMINOPURINE AND 2-AMINOADENINE CONJUGATES INTO OLIGONUCLEOTIDES | Alnylam Pharmaceuticals, Inc. (US) | 2024-05-22 | — | — | EP | disclosed |
| EP-4370503-A1 | ESTERS OF A RETINOID AND BAKUCHIOL AND PREPARATIONS THEREOF | Conagen Inc. (US) | 2024-05-22 | — | — | EP | disclosed |
| EP-4370132-A2 | MULTIPLEXING TARGETING LIGANDS THROUGH CLICK CHEMISTRY AT THE ANOMERIC SITE OF SUGARS | Alnylam Pharmaceuticals, Inc. (US) | 2024-05-22 | — | — | EP | disclosed |
| EP-4370587-A1 | AN AMINOSQUARAMIDE POLYMER | Universitat de les Illes Balears (ES) | 2024-05-22 | — | — | EP | disclosed |
| US-11986471-B2 | Compounds and methods of use | TANGO THERAPEUTICS, INC. (US) | 2024-05-21 | — | — | US | disclosed |
| US-11987599-B2 | Solid support for synthesizing nucleic acid sequences and methods for making and using | UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2024-05-21 | — | — | US | disclosed |
| US-20240158466-A1 | PEGYLATED P-SELECTIN INHIBITORS | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. (US) | 2024-05-16 | — | — | US | disclosed |
| EP-4367125-A1 | AMINOOXY CLICK CHEMISTRY (AOCC): A VERSATILE BIOCONJUGATION APPROACH | Alnylam Pharmaceuticals, Inc. (US) | 2024-05-15 | — | — | EP | disclosed |
| WO-2024097948-A1 | DEGRADERS OF MDM2 AND USES THEREOF | ROIVANT DISCOVERY, INC. (US) | 2024-05-10 | — | — | WO | disclosed |
| WO-2024097855-A2 | IDENTIFICATION OF SMALL MOLECULES THAT RECRUIT AND ACTIVATE RNASE L | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2024-05-10 | — | — | WO | disclosed |
| WO-2024097228-A1 | COMPOUNDS TARGETING CDK11 AND METHODS OF USING THE SAME | MELIORA THERAPEUTICS, INC. (US) | 2024-05-10 | — | — | WO | disclosed |
| WO-2024097746-A1 | ALKENE CYCLOPROPANATION WITH NICKEL CATALYST ENHANCER AND IMPROVED REARRANGEMENT REACTION | CONAGEN INC. (US) | 2024-05-10 | — | — | WO | disclosed |
| US-20240148889-A1 | STABILIZED TRIOXACARCIN ANTIBODY DRUG CONJUGATES AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2024-05-09 | — | — | US | disclosed |
| US-20240148885-A1 | TARGETED BIFUNCTIONAL DEGRADERS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2024-05-09 | — | — | US | disclosed |
| US-20240150375-A1 | MACROCYCLIC COMPOUNDS AND USES THEREOF | THESEUS PHARMACEUTICALS, INC. (US) | 2024-05-09 | — | — | US | disclosed |
| US-20240150371-A1 | Compounds for the Treatment of Kinase-Dependent Disorders | EXELIXIS, INC. | 2024-05-09 | — | — | US | disclosed |
| US-20240150756-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2024-05-09 | — | — | US | disclosed |
| EP-4362920-A1 | COMPOSITIONS FOR DELIVERY OF MRNA | Translate Bio, Inc. (US) | 2024-05-08 | — | — | EP | disclosed |
| EP-4362933-A1 | COMPLEMENT INHIBITION | Apellis Pharmaceuticals, Inc. (US) | 2024-05-08 | — | — | EP | disclosed |
| US-11975110-B2 | Cationic polymers | TRANSLATE BIO, INC. (US) | 2024-05-07 | — | — | US | disclosed |
| US-20240139233-A1 | ACTIVE AGENT-RELEASING HYALURONIC ACID VEHICLE | Ariel Scientific Innovations Ltd. (IL) | 2024-05-02 | — | — | US | disclosed |
| EP-4359380-A1 | PROCESSES FOR THE PREPARATION OF (S)-2-(2,6-DIOXOPIPERIDIN-3-YL)-4-((2-FLUORO-4-((3-MORPHOLINOAZETIDIN-1-YL) METHYL)BENZYL) AMINO)ISOINDOLINE-1,3-DIONE | Celgene Corporation (US) | 2024-05-01 | — | — | EP | disclosed |
| US-11969425-B2 | Inhibitor of indoleamine-2,3-dioxygenase (IDO) | INVENTISBIO LLC (US) | 2024-04-30 | — | — | US | disclosed |
| WO-2024086705-A2 | BICYCLIC ENHANCERS OF THE PARTICULATE GUANYLYL CYCLASE RECEPTOR A | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2024-04-25 | — | — | WO | disclosed |
| WO-2024086717-A2 | HETEROARYL ENHANCERS OF THE PARTICULATE GUANYLYL CYCLASE RECEPTOR A | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2024-04-25 | — | — | WO | disclosed |
| US-20240132894-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2024-04-25 | — | — | US | disclosed |
| US-20240131180-A1 | DRUG ANTIBODY CONJUGATES | PHARMA MAR, S.A. (ES) | 2024-04-25 | — | — | US | disclosed |
| WO-2024086826-A2 | POLYPEPTIDYL LINKERS | Quantum-Si Incorporated (US) | 2024-04-25 | — | — | WO | disclosed |
| WO-2024083210-A1 | COMPOUNDS, COMPOSITIONS AND METHODS THEREOF | HEPAITECH (BEIJING) BIOPHARMA TECHNOLOGY CO., LTD. (CN) | 2024-04-25 | — | — | WO | disclosed |
| EP-4355350-A1 | STAPLED PEPTIDES AND METHODS THEREOF | Fog Pharmaceuticals, Inc. (US) | 2024-04-24 | — | — | EP | disclosed |
| WO-2024081939-A2 | GLYCOGEN SYNTHASE KINASE 3 INHIBITORS AND USES THEREOF | THE BROAD INSTITUTE, INC. (US) | 2024-04-18 | — | — | WO | disclosed |
| US-20240122942-A1 | METHODS AND COMPOSITIONS FOR REDUCING BODY FAT AND ADIPOCYTES | TOPOKINE THERAPEUTICS, INC. | 2024-04-18 | — | — | US | disclosed |
| US-20240124406-A1 | INHIBITORS OF TRANSCRIPTIONAL ENHANCED ASSOCIATE DOMAIN (TEAD) AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. | 2024-04-18 | — | — | US | disclosed |
| US-20240124525-A1 | PROLINE-LOCKED STAPLED PEPTIDES AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2024-04-18 | — | — | US | disclosed |
| US-20240122943-A1 | METHODS AND COMPOSITIONS FOR REDUCING BODY FAT AND ADIPOCYTES | TOPOKINE THERAPEUTICS, INC. | 2024-04-18 | — | — | US | disclosed |
| WO-2024077023-A2 | CEREBLON-RECRUITING BCL-XL/BCL-2 DUAL DEGRADERS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2024-04-11 | — | — | WO | disclosed |
| US-20240116985-A1 | STAPLED PEPTIDES AND METHODS THEREOF | PARABILIS MEDICINES, INC. | 2024-04-11 | — | — | US | disclosed |
| US-20240116973-A1 | MODIFIED OLIGONUCLEOTIDES | ALNYLAM PHARMACEUTICALS, INC. (US) | 2024-04-11 | — | — | US | disclosed |
| US-20240118281-A1 | ANTICANCER COMPOUNDS AND USES THEREOF | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2024-04-11 | — | — | US | disclosed |
| US-20240117347-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2024-04-11 | — | — | US | disclosed |
| WO-2024073497-A2 | SMALL MOLECULE DEGRADERS OF HIV-1 TAT PROTEIN | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2024-04-04 | — | — | WO | disclosed |
| WO-2024073709-A2 | MODIFIED OLIGONUCLEOTIDES AND DOUBLE-STRANDED RNAS | ALNYLAM PHARMACEUTICALS, INC. (US) | 2024-04-04 | — | — | WO | disclosed |
| WO-2024073745-A1 | INHIBITORS OF EGFR OR HER2 AND METHODS OF USE | ARBELLA THERAPEUTICS, LLC (US) | 2024-04-04 | — | — | WO | disclosed |
| EP-4344744-A2 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | Wave Life Sciences Ltd. (SG) | 2024-04-03 | — | — | EP | disclosed |
| US-11945816-B2 | Inhibitors of EGFR and/or HER2 and methods of use | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2024-04-02 | — | — | US | disclosed |
| WO-2024064769-A1 | INDUCTION OF STEM-LIKE ACTIVATED T CELLS | PHIO PHARMACEUTICALS CORP. (US) | 2024-03-28 | — | — | WO | disclosed |
| US-20240102018-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | AMYLYX PHARMACEUTICALS, INC. | 2024-03-28 | — | — | US | disclosed |
| US-20240100199-A1 | COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS | LANTHEUS MEDICAL IMAGING, INC. (US) | 2024-03-28 | — | — | US | disclosed |
| WO-2024064214-A2 | SYNTHESIS OF CYCLOPROPANE CARBOXYLIC ACIDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2024-03-28 | — | — | WO | disclosed |
| WO-2023283434-A9 | AMINOOXY CLICK CHEMISTRY (AOCC): A VERSATILE BIOCONJUGATION APPROACH | ALNYLAM PHARMACEUTICALS, INC. (US) | 2024-03-28 | — | — | WO | disclosed |
| US-20240100177-A1 | ANTIBODY-OLIGONUCLEOTIDE COMPLEXES AND USES THEREOF | DYNE THERAPEUTICS, INC. (US) | 2024-03-28 | — | — | US | disclosed |
| US-20240101559-A1 | TRICYCLIC KINASE INHIBITORS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2024-03-28 | — | — | US | disclosed |
| US-20240102017-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | AMYLYX PHARMACEUTICALS, INC. | 2024-03-28 | — | — | US | disclosed |
| EP-4340859-A1 | ANTIBODY DRUG CONJUGATES USING MATES TECHNOLOGY FOR DELIVERING CYTOTOXIC AGENTS | Biohaven Therapeutics Ltd. (US) | 2024-03-27 | — | — | EP | disclosed |
| US-11939408-B2 | Hyaluronic acid derivatives | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2024-03-26 | — | — | US | disclosed |
| WO-2024059096-A2 | C5AR1 ANTAGONISTS AND USES THEREOF | VANQUA BIO, INC. (US) | 2024-03-21 | — | — | WO | disclosed |
| US-20240091213-A1 | COMPOUNDS FOR TAU PROTEIN DEGRADATION | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2024-03-21 | — | — | US | disclosed |
| WO-2024059107-A1 | IKZF2 AND CK1-ALPHA DEGRADING COMPOUNDS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2024-03-21 | — | — | WO | disclosed |
| EP-4337665-A1 | MACROCYCLIC COMPOUNDS AND USES THEREOF | Theseus Pharmaceuticals, Inc. (US) | 2024-03-20 | — | — | EP | disclosed |
| EP-4337639-A1 | NAMPT INHIBITORS AND USES THEREOF | Remedy Plan, Inc. (US) | 2024-03-20 | — | — | EP | disclosed |
| EP-4025253-B1 | DRUG ANTIBODY CONJUGATES | PHARMA MAR SA (ES) | 2024-03-20 | — | — | EP | disclosed |
| US-11932625-B2 | Inhibitors of cyclin-dependent kinase 12 (CDK12) and uses thereof | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2024-03-19 | — | — | US | disclosed |
| US-11931346-B2 | Uses of 4′-desferrithiocin analogs | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2024-03-19 | — | — | US | disclosed |
| US-20240083934-A1 | N-ACETYLGALACTOSAMINE (GALNAC)-DERIVED COMPOUNDS AND OLIGONUCLEOTIDES | ADARX PHARMACEUTICALS, INC. (US) | 2024-03-14 | — | — | US | disclosed |
| US-20240083936-A1 | STEROIDAL COMPOUND DERIVATIVES AS THERAPEUTIC AGENTS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2024-03-14 | — | — | US | disclosed |
| WO-2024054682-A2 | ULTRALOW MOLECULAR WEIGHT HEPARIN | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2024-03-14 | — | — | WO | disclosed |
| US-20240083943-A1 | VEGF-REGULATING PEPTIDES | IDP DISCOVERY PHARMA, S.L. (ES) | 2024-03-14 | — | — | US | disclosed |
| US-11926828-B2 | Methods for treating aging and skin disorders using nucleic acids targeting TYR or MMP1 | PHIO PHARMACEUTICALS CORP. (US) | 2024-03-12 | — | — | US | disclosed |
| US-20240075151-A1 | CONJUGATES OF TUMOR NECROSIS FACTOR INHIBITORS TO FUNCTIONALIZED POLYMERS | FISH & RICHARDSON PC | 2024-03-07 | — | — | US | disclosed |
| WO-2024050554-A2 | SYNTHESIS OF COTYLENIN AND ANALOGS THEREOF FOR THE DEVELOPMENT OF SELECTIVE MODULATORS OF 14-3-3 PROTEIN-PROTEIN INTERACTION | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2024-03-07 | — | — | WO | disclosed |
| WO-2024047112-A1 | HALOGENATED SOMATOSTATIN ANALOGS WITH MULTIPLE SOMATOSTATIN RECEPTOR SUBTYPE SELECTIVITY | SOMTHERANOSTICS SARL (CH) | 2024-03-07 | — | — | WO | disclosed |
| EP-4330253-A1 | TRANSCRIPTIONAL ENHANCED ASSOCIATED DOMAIN (TEAD) TRANSCRIPTION FACTOR INHIBITORS AND USES THEREOF | Dana-Farber Cancer Institute, Inc. (US) | 2024-03-06 | — | — | EP | disclosed |
| EP-4329762-A1 | SOLUBLE ADENYLYL CYCLASE (SAC) INHIBITORS AND USES THEREOF | Cornell University (US) | 2024-03-06 | — | — | EP | disclosed |
| EP-4329881-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | Vanqua Bio, Inc. (US) | 2024-03-06 | — | — | EP | disclosed |
| EP-4329880-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | Vanqua Bio, Inc. (US) | 2024-03-06 | — | — | EP | disclosed |
| US-11919886-B2 | 4,9-dioxo-4,9-dihydronaphtho[2,3-B]furan-3-carboxamide derivatives and uses thereof for treating proliferative diseases and infectious diseases | ACADEMIA SINICA (TW) | 2024-03-05 | — | — | US | disclosed |
| US-11919922-B2 | Bicyclic nucleosides and oligomers prepared therefrom | UNIVERSITAT BERN (CH) | 2024-03-05 | — | — | US | disclosed |
| US-11918984-B2 | Annulation catalysts via direct C—H bond amination | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2024-03-05 | — | — | US | disclosed |
| WO-2024044653-A2 | SILYL CARBAMATES AND POLY(SILYL CARBAMATES) AND USES THEREOF | MASSACHUESETTS INSTITUE OF TECHNOLOGY (US) | 2024-02-29 | — | — | WO | disclosed |
| WO-2024044651-A2 | DEGRADABLE POLYURETHANES CONTAINING SILYL ETHER LINKERS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2024-02-29 | — | — | WO | disclosed |
| EP-4326338-A1 | IMPROVED COMPOSITIONS FOR DELIVERY OF MRNA | Translate Bio, Inc. (US) | 2024-02-28 | — | — | EP | disclosed |
| US-11912644-B2 | Processes for the preparation of (S)-tert-butyl 4,5-diamino-5-oxopentanoate | CELGENE CORPORATION (US) | 2024-02-27 | — | — | US | disclosed |
| US-20240059689-A1 | PURINE DERIVATIVES AS ANTICANCER AGENTS | MEDIVIR AB (SE) | 2024-02-22 | — | — | US | disclosed |
| EP-4323377-A1 | VACCINES | Adjuvance Technologies, Inc. (US) | 2024-02-21 | — | — | EP | disclosed |
| EP-4323346-A1 | GOOD\"BUFFER-BASED CATIONIC LIPIDS | Translate Bio, Inc. (US) | 2024-02-21 | — | — | EP | disclosed |
| EP-4323340-A2 | E3 LIGASE BINDERS AND USES THEREOF | President and Fellows of Harvard College (US) | 2024-02-21 | — | — | EP | disclosed |
| US-11905285-B2 | Inhibitors of plasma kallikrein and uses thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2024-02-20 | — | — | US | disclosed |
| US-11903910-B2 | Use of metformin and analogs thereof to reduce RAN protein levels in the treatment of neurological disorders | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2024-02-20 | — | — | US | disclosed |
| US-11905525-B2 | Reduction of elimination of immune responses to non-intravenous, e.g., subcutaneously administered therapeutic proteins | MODERNATX, INC. (US) | 2024-02-20 | — | — | US | disclosed |
| US-11897905-B2 | Degradable polymers of a cyclic silyl ether and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2024-02-13 | — | — | US | disclosed |
| WO-2023129564-A9 | DEGRADERS OF GRK2 AND USES THEREOF | CYGNAL THERAPEUTICS, INC. (US) | 2024-02-08 | — | — | WO | disclosed |
| US-20240043414-A1 | Compounds for the Treatment of Kinase-Dependent Disorders | EXELIXIS, INC. | 2024-02-08 | — | — | US | disclosed |
| US-20240043442-A1 | SELECTIVE ESTROGEN RECEPTOR DEGRADERS AND USES THEREOF | INVENTISBIO LLC | 2024-02-08 | — | — | US | disclosed |
| EP-4314000-A1 | SYNTHESIS OF TRINUCLEOTIDE AND TETRANUCLEOTIDE CAPS FOR MRNA PRODUCTION | ModernaTX, Inc. (US) | 2024-02-07 | — | — | EP | disclosed |
| US-11890377-B2 | Lipid formulations for delivery of messenger RNA | TRANSLATE BIO, INC. (US) | 2024-02-06 | — | — | US | disclosed |
| US-11891448-B2 | Glycated CD59 peptides, their preparation, and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2024-02-06 | — | — | US | disclosed |
| WO-2024026353-A2 | ENZYMATIC SYNTHESIS OF MYCOSPORINE-LIKE AMINO ACIDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2024-02-01 | — | — | WO | disclosed |
| US-20240034726-A9 | MAP KINASE KINASE (MKK7) INHIBITORS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2024-02-01 | — | — | US | disclosed |
| US-11883500-B2 | Phosphonate linkers and their use to facilitate cellular retention of compounds | MERCK SHARP & DOHME LLC (US) | 2024-01-30 | — | — | US | disclosed |
| WO-2024020188-A2 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | AMYLYX PHARMACEUTICALS, INC. (US) | 2024-01-25 | — | — | WO | disclosed |
| US-20240026358-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2024-01-25 | — | — | US | disclosed |
| EP-4308566-A1 | PURINE DERIVATIVES AS ANTICANCER AGENTS | Tango Therapeutics, Inc. (US) | 2024-01-24 | — | — | EP | disclosed |
| EP-4310496-A2 | COMPOUNDS FOR TAU PROTEIN DEGRADATION | Dana-Farber Cancer Institute, Inc. (US) | 2024-01-24 | — | — | EP | disclosed |
| US-11878019-B2 | Uses of pyrimidopyrimidinones as SIK inhibitors | THE GENERAL HOSPITAL CORPORATION (US) | 2024-01-23 | — | — | US | disclosed |
| WO-2024015560-A1 | COMBINATION OF MACROPHAGE-DIRECTED IMMUNOTHERAPY AND CYTOKINES FOR TREATMENT OF CANCER | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2024-01-18 | — | — | WO | disclosed |
| WO-2024015958-A1 | CYCLIC PEPTIDE INHIBITORS OF IL-23 | JANSSEN PHARMACEUTICA NV (BE) | 2024-01-18 | — | — | WO | disclosed |
| US-11872239-B2 | Modified oligomeric compounds comprising tricyclo-DNA nucleosides and uses thereof | SYNTHENA AG (CH) | 2024-01-16 | — | — | US | disclosed |
| WO-2024006953-A2 | MONOMERS AND METHODS FOR SYNTHESIS OF MODIFIED OLIGONUCLEOTIDES | ALNYLAM PHARMACEUTICALS, INC. (US) | 2024-01-04 | — | — | WO | disclosed |
| EP-3615544-B9 | ANTITUMORAL COMPOUNDS | PHARMA MAR SA (ES) | 2024-01-03 | — | — | EP | disclosed |
| EP-4101855-B9 | ANTITUMORAL COMPOUNDS | PHARMA MAR SA (ES) | 2024-01-03 | — | — | EP | disclosed |
| EP-3710454-B1 | MACROCYCLIC COMPOUNDS AND USES THEREOF | HARVARD COLLEGE (US) | 2024-01-03 | — | — | EP | disclosed |
| EP-2885416-B1 | LARGE SCALE ENZYMATIC SYNTHESIS OF OLIGOSACCHARIDES | ACADEMIA SINICA (TW) | 2024-01-03 | — | — | EP | disclosed |
| EP-3715346-B1 | THIAZOLYL-CONTAINING COMPOUNDS FOR TREATING PROLIFERATIVE DISEASES | DANA FARBER CANCER INST INC (US) | 2024-01-03 | — | — | EP | disclosed |
| WO-2023250342-A2 | CYCLOPROPENE PHOSPHORAMIDITES AND CONJUGATES THEREOF | Quantum-Si Incorporated (US) | 2023-12-28 | — | — | WO | disclosed |
| US-20230416263-A1 | CARM1 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2023-12-28 | — | — | US | disclosed |
| US-20230416283-A1 | CROSSLINKING COMONOMERS FOR HIGH PERFORMANCE DEGRADABLE THERMOSETS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2023-12-28 | — | — | US | disclosed |
| WO-2023250116-A1 | INDOCYANINE GREEN (ICG) MODIFICATION FOR TREATMENT OF LIVER CANCER | THE CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2023-12-28 | — | — | WO | disclosed |
| EP-4294392-A1 | TARGETED BIFUNCTIONAL DEGRADERS AND METHODS USING SAME | Yale University, Inc. (US) | 2023-12-27 | — | — | EP | disclosed |
| EP-4294384-A1 | TARGETED BIFUNCTIONAL DEGRADERS | Yale University (US) | 2023-12-27 | — | — | EP | disclosed |
| US-11850216-B2 | 18F labeling of proteins using sortases | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2023-12-26 | — | — | US | disclosed |
| WO-2023241620-A1 | BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF | SUZHOU KEEN THERAPEUTICS CO., LTD. (CN) | 2023-12-21 | — | — | WO | disclosed |
| EP-3407916-B1 | PHOSPHONATE LINKERS AND THEIR USE TO FACILITATE CELLULAR RETENTION OF COMPOUNDS | MERCK SHARP & DOHME LLC (US) | 2023-12-20 | — | — | EP | disclosed |
| EP-4291559-A1 | PYRROLO[3,2-D]PYRIMIDINE COMPOUNDS AND METHODS OF USE IN THE TREATMENT OF CANCER | Tango Therapeutics, Inc. (US) | 2023-12-20 | — | — | EP | disclosed |
| EP-3486269-B1 | POLYMERIZATION SYSTEM FOR THE COPOLYMERIZATION OF CO2 AND EPOXIDES AND RELATED METHOD | SAUDI ARAMCO TECH CO (SA) | 2023-12-20 | — | — | EP | disclosed |
| WO-2023239925-A1 | CYCLOPHILIN INHIBITORS AND USES THEREOF | THE BROAD INSTITUTE, INC. (US) | 2023-12-14 | — | — | WO | disclosed |
| EP-4288110-A2 | TECHNOLOGIES FOR PREVENTING OR TREATING INFECTIONS | Biohaven Therapeutics Ltd. (US) | 2023-12-13 | — | — | EP | disclosed |
| EP-4288465-A1 | ACTIVE AGENT-RELEASING HYALURONIC ACID VEHICLE | Ariel Scientific Innovations Ltd. (IL) | 2023-12-13 | — | — | EP | disclosed |
| US-20230391768-A2 | IMIDAZOPYRIDINE DERIVATIVES AND AZA-IMIDAZOPYRIDINE DERIVATIVES AS JANUS KINASE 2 INHIBITORS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2023-12-07 | — | — | US | disclosed |
| US-20230391799-A1 | FLUORESCENT DYE FOR PROTEIN OR NUCLEIC ACID LABELLING | Quantum-Si Incorporated (US) | 2023-12-07 | — | — | US | disclosed |
| US-20230392137-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-12-07 | — | — | US | disclosed |
| EP-4284854-A1 | REPROCESSABLE COMPOSITIONS | Massachusetts Institute of Technology (US) | 2023-12-06 | — | — | EP | disclosed |
| US-11834455-B2 | Carm1 inhibitors and uses thereof | Epizyme, Inc. (US) | 2023-12-05 | — | — | US | disclosed |
| WO-2023227771-A1 | CYCLIC PEPTIDES WITH ANTIBACTERIAL ACTIVITY AGAINST MULTIDRUG RESISTANT (MDR) PATHOGENS | Fundación Privada Instituto De Salud Global Barcelona (ES) | 2023-11-30 | — | — | WO | disclosed |
| US-20230382865-A1 | HISTONE DEMETHYLASE 5 INHIBITORS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2023-11-30 | — | — | US | disclosed |
| WO-2023230336-A2 | BIOCATALYTIC SYNTHESIS OF UNNATURAL MYCOSPORINE-LIKE AMINO ACIDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2023-11-30 | — | — | WO | disclosed |
| WO-2023230308-A1 | DEGRADER COMPOUNDS OF QSOX1 mRNA | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2023-11-30 | — | — | WO | disclosed |
| EP-4281445-A1 | DEGRADERS OF GRK2 AND USES THEREOF | Sonata Therapeutics, Inc. (US) | 2023-11-29 | — | — | EP | disclosed |
| EP-2337809-B2 | POLYCARBONATE POLYOL COMPOSITIONS AND METHODS | SAUDI ARAMCO TECH CO (SA) | 2023-11-29 | — | — | EP | disclosed |
| US-11827744-B2 | Bottlebrush copolymers and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2023-11-28 | — | — | US | disclosed |
| WO-2023225631-A1 | INTERCALATING SUGAR MOLECULES | XALUD THERAPEUTICS, INC. (US) | 2023-11-23 | — | — | WO | disclosed |
| WO-2023196714-A9 | INHIBITORS OF DDR1 AND DDR2 FOR THE TREATMENT OF ARTHRITIS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-11-23 | — | — | WO | disclosed |
| US-20230374006-A1 | HETEROARYL COMPOUNDS AND USES THEREOF | APRINOIA THERAPEUTICS LIMITED (CN) | 2023-11-23 | — | — | US | disclosed |
| US-20230374024-A1 | Compounds for the Treatment of Kinase-Dependent Disorders | EXELIXIS, INC. | 2023-11-23 | — | — | US | disclosed |
| EP-4277919-A1 | PEGYLATED P-SELECTIN INHIBITORS | Beth Israel Deaconess Medical Center, Inc. (US) | 2023-11-22 | — | — | EP | disclosed |
| EP-4277636-A1 | MODIFIED OLIGONUCLEOTIDES | Alnylam Pharmaceuticals, Inc. (US) | 2023-11-22 | — | — | EP | disclosed |
| WO-2023220087-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | AMYLYX PHARMACEUTICALS, INC. (US) | 2023-11-16 | — | — | WO | disclosed |
| WO-2023220440-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-11-16 | — | — | WO | disclosed |
| WO-2023220737-A2 | OLIGONUCLEOTIDES HAVING A SYNTHETIC BACKBONE AND SYNTHESIS THEREOF | ADARX PHARMACEUTICALS, INC. (US) | 2023-11-16 | — | — | WO | disclosed |
| US-20230365646-A1 | AZIDE INSULIN ANALOGUES | MERCK SHARP & DOHME LLC (US) | 2023-11-16 | — | — | US | disclosed |
| EP-2970107-B1 | PHOTOSWITCHABLE HDAC INHIBITORS | MASSACHUSETTS GEN HOSPITAL (US) | 2023-11-15 | — | — | EP | disclosed |
| US-11814398-B2 | Macrocyclic compounds and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-11-14 | — | — | US | disclosed |
| US-11814379-B2 | Cyano quinoline amide compounds as HER2 inhibitors and methods of use | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2023-11-14 | — | — | US | disclosed |
| WO-2023215289-A1 | FLUORESCENT DYE FOR PROTEIN OR NUCLEIC ACID LABELING | Quantum-Si Incorporated (US) | 2023-11-09 | — | — | WO | disclosed |
| US-20230357140-A1 | TES-BASED CATIONIC LIPIDS | TRANSLATE BIO, INC. | 2023-11-09 | — | — | US | disclosed |
| US-20230357166-A1 | PIPERAZINE-BASED CATIONIC LIPIDS | TRANSLATE BIO, INC. | 2023-11-09 | — | — | US | disclosed |
| US-20230357320-A1 | HELICAL STAPLED PEPTIDES AND USES THEREOF | PARABILIS MEDICINES, INC. | 2023-11-09 | — | — | US | disclosed |
| US-20230357302-A1 | TRITERPENE SAPONIN VARIANTS, METHODS OF SYNTHESIS AND USE THEREOF | MEMORIAL SLOAN-KETTERING CANCER CENTER | 2023-11-09 | — | — | US | disclosed |
| US-20230357286-A1 | KETONE SYNTHESIS AND APPLICATIONS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-11-09 | — | — | US | disclosed |
| US-20230357300-A1 | TRITERPENE SAPONIN SYNTHESIS, INTERMEDIATES AND ADJUVANT COMBINATIONS | ADJUVANCE TECHNOLOGIES, INC. (US) | 2023-11-09 | — | — | US | disclosed |
| EP-4271480-A1 | VEGF-REGULATING PEPTIDES | IDP Discovery Pharma, S.L. (ES) | 2023-11-08 | — | — | EP | disclosed |
| US-20230346942-A1 | MACROMOLECULAR PRODRUGS FOR LIGHT-EMITTING DIODES AND USES THEREOF | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2023-11-02 | — | — | US | disclosed |
| US-11802132-B2 | Small molecules for inducing selective protein degradation and uses thereof | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2023-10-31 | — | — | US | disclosed |
| US-20230338577-A1 | ALKENYL SUBSTITUTED 2,5-PIPERAZINEDIONES, COMPOSITIONS, AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2023-10-26 | — | — | US | disclosed |
| US-20230339865-A1 | QUINAZOLINE-DERIVED HCK INHIBITORS FOR USE IN THE TREATMENT OF MYD88 MUTATED DISEASES | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2023-10-26 | — | — | US | disclosed |
| US-20230338373-A1 | INHIBITOR OF INDOLEAMINE-2,3-DIOXYGENASE (IDO) | INVENTISBIO LLC | 2023-10-26 | — | — | US | disclosed |
| WO-2023205206-A1 | LINCOSAMIDES AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-10-26 | — | — | WO | disclosed |
| US-11793823-B2 | Compounds and pharmaceutical uses thereof | SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) | 2023-10-24 | — | — | US | disclosed |
| WO-2023201095-A2 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO | WAVE LIFE SCIENCES LTD. (SG) | 2023-10-19 | — | — | WO | disclosed |
| WO-2023198857-A1 | \"GOOD\" BUFFER-BASED CATIONIC LIPIDS | SANOFI (FR) | 2023-10-19 | — | — | WO | disclosed |
| WO-2023201005-A2 | HYDROPHOBIC POLYMER AEROGELS | AEROGEL TECHNOLOGIES, LLC (US) | 2023-10-19 | — | — | WO | disclosed |
| US-20230330240-A1 | TECHNOLOGIES FOR PREVENTING OR TREATING INFECTIONS | BIOHAVEN THERAPEUTICS LTD (US) | 2023-10-19 | — | — | US | disclosed |
| US-20230330105-A1 | METHODS AND COMPOSITIONS FOR TOPICAL DELIVERY OF PROSTAGLANDINS TO SUBCUTANEOUS FAT | TOPOKINE THERAPEUTICS, INC. | 2023-10-19 | — | — | US | disclosed |
| EP-3606528-B1 | TRICYCLIC COMPOUNDS AS GLYCOGEN SYNTHASE KINASE 3 (GSK3) INHIBITORS AND USES THEREOF | BROAD INST INC (US) | 2023-10-18 | — | — | EP | disclosed |
| WO-2023196714-A2 | INHIBITORS OF DDR1 AND DDR2 FOR THE TREATMENT OF ARTHRITIS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-10-12 | — | — | WO | disclosed |
| US-20230322747-A1 | OXADIAZOLE HDAC6 INHIBITORS AND USES THEREOF | EIKONIZO THERAPEUTICS, INC. (US) | 2023-10-12 | — | — | US | disclosed |
| WO-2023196605-A1 | INHIBITING HISTONE DEACETYLASE 6 (HDAC6) | EIKONIZO THERAPEUTICS, INC. (US) | 2023-10-12 | — | — | WO | disclosed |
| WO-2023196601-A1 | OXADIAZOLE HDAC6 INHIBITORS AND USES THEREOF | EIKONIZO THERAPEUTICS, INC. (US) | 2023-10-12 | — | — | WO | disclosed |
| WO-2023196342-A1 | α4β1/7 INTEGRIN LIGAND CONJUGATED COMPOUNDS AND USES THEREOF | ADARX PHARMACEUTICALS, INC. (US) | 2023-10-12 | — | — | WO | disclosed |
| EP-4255447-A1 | ANTIBODY-OLIGONUCLEOTIDE COMPLEXES AND USES THEREOF | Dyne Therapeutics, Inc. (US) | 2023-10-11 | — | — | EP | disclosed |
| US-20230312649-A1 | MELANOCYTE-REGULATING PEPTIDES | IDP DISCOVERY PHARMA, S.L. (ES) | 2023-10-05 | — | — | US | disclosed |
| EP-3652329-B1 | COMPOUNDS FOR TAU PROTEIN DEGRADATION | DANA FARBER CANCER INST INC (US) | 2023-10-04 | — | — | EP | disclosed |
| US-11773219-B2 | Functionalized polymers | QUIAPEG PHARMACEUTICALS AB (SE) | 2023-10-03 | — | — | US | disclosed |
| US-20230303512-A1 | MODULATORS OF MYB-MEDIATED TRANSCRIPTION AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2023-09-28 | — | — | US | disclosed |
| EP-4248988-A2 | ALKENYL SUBSTITUTED 2,5-PIPERAZINEDIONES AND THEIR USE IN COMPOSITIONS FOR DELIVERING AN AGENT TO A SUBJECT OR CELL | Massachusetts Institute of Technology (US) | 2023-09-27 | — | — | EP | disclosed |
| US-11767341-B2 | Lincosamide antibiotics and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-09-26 | — | — | US | disclosed |
| US-20230295617-A1 | METHODS AND COMPOSITIONS OF BIOLOGICALLY ACTIVE AGENTS | WAVE LIFE SCIENCES LTD. (SG) | 2023-09-21 | — | — | US | disclosed |
| WO-2022159688-A9 | DEGRADERS OF GRK2 AND USES THEREOF | SONATA THERAPEUTICS, INC. (US) | 2023-09-21 | — | — | WO | disclosed |
| EP-4245369-A2 | NEUROACTIVE STEROIDS, COMPOSITIONS, AND USES THEREOF | Sage Therapeutics, Inc. (US) | 2023-09-20 | — | — | EP | disclosed |
| US-20230285574-A1 | CONJUGATES OF BIOLOGICALLY ACTIVE MOLECULES TO FUNCTIONALIZED POLYMERS | FISH & RICHARDSON PC | 2023-09-14 | — | — | US | disclosed |
| US-20230287037-A1 | 3,3 DISUBSTITUTED 19-NOR PREGNANE COMPOUNDS, COMPOSITIONS, AND USES THEREOF | SAGE THERAPEUTICS, INC. | 2023-09-14 | — | — | US | disclosed |
| EP-4240784-A1 | CROSSLINKING COMONOMERS FOR HIGH PERFORMANCE DEGRADABLE THERMOSETS | Massachusetts Institute of Technology (US) | 2023-09-13 | — | — | EP | disclosed |
| EP-4240849-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | Wave Life Sciences Ltd. (SG) | 2023-09-13 | — | — | EP | disclosed |
| US-11753400-B2 | D-amino acid oxidase inhibitors and therapeutic uses thereof | SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) | 2023-09-12 | — | — | US | disclosed |
| US-11752221-B2 | Brush-arm star polymer imaging agents and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2023-09-12 | — | — | US | disclosed |
| WO-2023168077-A1 | PHENOL-BASED HOT MELT ADHESIVES FOR REWORK, REPAIR AND RECYCLE | CONAGEN INC. (US) | 2023-09-07 | — | — | WO | disclosed |
| WO-2023168045-A1 | HYDROXY/AMINO OXIME-BASED HOT MELT ADHESIVES FOR REWORK, REPAIR AND RECYCLE | CONAGEN INC. (US) | 2023-09-07 | — | — | WO | disclosed |
| US-20230278986-A1 | ARYL HYDROCARBON RECEPTOR MODULATORS AND USES THEREOF | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. (US) | 2023-09-07 | — | — | US | disclosed |
| WO-2023168066-A1 | OXIME-BASED HOT MELT ADHESIVES FOR REWORK, REPAIR AND RECYCLE | CONAGEN INC. (US) | 2023-09-07 | — | — | WO | disclosed |
| WO-2023168296-A2 | CB1 LIGAND CONJUGATED COMPOUNDS AND USES THEREOF | ADARX PHARMACEUTICALS, INC. (US) | 2023-09-07 | — | — | WO | disclosed |
| US-20230279020-A9 | CARM1 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2023-09-07 | — | — | US | disclosed |
| EP-4238979-A1 | BETA-STRAND TYPE CROSSLINKED PEPTIDE | Xeno-Interface Inc. (JP) | 2023-09-06 | — | — | EP | disclosed |
| US-11744906-B2 | Compositions, methods, and systems for the synthesis and use of imaging agents | LANTHEUS MEDICAL IMAGING, INC. (US) | 2023-09-05 | — | — | US | disclosed |
| US-11746364-B2 | Enzymatic synthesis of kavalactones and flavokavains | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2023-09-05 | — | — | US | disclosed |
| US-20230271917-A1 | AMINO ACIDS | PARABILIS MEDICINES, INC. | 2023-08-31 | — | — | US | disclosed |
| US-20230271998-A1 | SOLID SUPPORT FOR SYNTHESIZING NUCLEIC ACID SEQUENCES AND METHODS FOR MAKING AND USING | UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2023-08-31 | — | — | US | disclosed |
| US-11739354-B2 | Enzymatic synthesis of kavalactones and flavokavains | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2023-08-29 | — | — | US | disclosed |
| US-11739046-B2 | Co-crystals of lithium benzoate and uses thereof | SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) | 2023-08-29 | — | — | US | disclosed |
| US-11739325-B2 | Oligonucleotide compositions and methods thereof | WAVE LIFE SCIENCES LTD. (SG) | 2023-08-29 | — | — | US | disclosed |
| US-20230263886-A1 | VACCINES, VACCINE PRIMING, AND ANTIGEN DOSE SPARING | ADJUVANCE TECHNOLOGIES, INC. | 2023-08-24 | — | — | US | disclosed |
| EP-2794719-B1 | METHODS FOR POLYMER SYNTHESIS | SAUDI ARAMCO TECH CO (SA) | 2023-08-23 | — | — | EP | disclosed |
| US-11731928-B2 | Co-crystals of sodium benzoate and uses thereof | SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) | 2023-08-22 | — | — | US | disclosed |
| US-11730810-B2 | Composition comprising an antigen and a substituted imidazo[1,2-a]pyrimidine for enhancing human immune response | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2023-08-22 | — | — | US | disclosed |
| WO-2023154756-A2 | THIONOLACTONES AS ADDITIVES FOR VINYL NETWORK DEGRADATION | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2023-08-17 | — | — | WO | disclosed |
| WO-2022178428-A9 | TARGETED BIFUNCTIONAL DEGRADERS AND METHODS USING SAME | YALE UNIVERSITY (US) | 2023-08-17 | — | — | WO | disclosed |
| US-20230255957-A1 | VIRAL ENTRY INHIBITORS AND RNA POLYMERASE INHIBITORS | SELVA THERAPEUTICS, INC. | 2023-08-17 | — | — | US | disclosed |
| US-20230257353-A1 | IONIZABLE LIPIDOIDS AND THEIR USES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2023-08-17 | — | — | US | disclosed |
| EP-4225915-A1 | OLIGOMERIC COMPOUND FOR DYSTROPHIN RESCUE IN DMD PATIENTS THROUGHOUT SKIPPING OF EXON-51 | SQY Therapeutics (FR) | 2023-08-16 | — | — | EP | disclosed |
| EP-4225322-A1 | N-ACETYLGALACTOSAMINE(GALNAC)-DERIVED COMPOUNDS AND OLIGONUCLEOTIDES | Adarx Pharmaceuticals, Inc. (US) | 2023-08-16 | — | — | EP | disclosed |
| US-11725011-B2 | Bicyclic urea kinase inhibitors and uses thereof | THE GENERAL HOSPITAL CORPORATION (US) | 2023-08-15 | — | — | US | disclosed |
| US-11723981-B2 | Conjugates of tumor necrosis factor inhibitors to functionalized polymers | QUIAPEG PHARMACEUTICALS AB (SE) | 2023-08-15 | — | — | US | disclosed |
| WO-2023150203-A1 | HDAC6 INHIBITORS AND USES THEREOF | EIKONIZO THERAPEUTICS, INC. (US) | 2023-08-10 | — | — | WO | disclosed |
| US-20230242534-A9 | INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2023-08-03 | — | — | US | disclosed |
| WO-2023146987-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
| WO-2023146991-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
| US-20230242565-A1 | Macrolides with Modified Desosamine Sugars and Uses Thereof | ZIKANI THERAPEUTICS, INC. | 2023-08-03 | — | — | US | disclosed |
| WO-2023146990-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
| WO-2023146892-A1 | BIPHENYL-SUBSTITUTED EPITHELIAL SODIUM CHANNEL BLOCKING COMPOUNDS | PARION SCIENCES, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
| WO-2023146989-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
| WO-2023146896-A1 | BICYCLIC-SUBSTITUTED EPITHELIAL SODIUM CHANNEL BLOCKING COMPOUNDS | PARION SCIENCES, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
| EP-4219465-A2 | PRMT5 INHIBITORS AND USES THEREOF | Epizyme Inc (US) | 2023-08-02 | — | — | EP | disclosed |
| EP-4101855-B1 | ANTITUMORAL COMPOUNDS | PHARMA MAR SA (ES) | 2023-08-02 | — | — | EP | disclosed |
| EP-4218833-A1 | LABELING OF ANTIBODIES | Whitehead Institute for Biomedical Research (US) | 2023-08-02 | — | — | EP | disclosed |
| EP-4219516-A2 | CHIRAL CONTROL | Wave Life Sciences Ltd. (SG) | 2023-08-02 | — | — | EP | disclosed |
| EP-4216933-A1 | PIPERAZINE-BASED CATIONIC LIPIDS | Translate Bio, Inc. (US) | 2023-08-02 | — | — | EP | disclosed |
| EP-3159352-B1 | STITCHED POLYPEPTIDES | HARVARD COLLEGE (US) | 2023-08-02 | — | — | EP | disclosed |
| US-11713325-B2 | Antitumoral compounds | PHARMA MAR, S.A. (ES) | 2023-08-01 | — | — | US | disclosed |
| US-20230233549-A1 | METHODS OF USING 4(1H)-QUINOLONE DERIVATIVES | ACADEMIA SINICA (TW) | 2023-07-27 | — | — | US | disclosed |
| WO-2023141470-A2 | IMMUNOMODULATORY LIPIDS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-07-27 | — | — | WO | disclosed |
| US-20230234914-A1 | PROCESSES FOR THE PREPARATION OF (S)-TERT-BUTYL 4,5-DIAMINO-5-OXOPENTANOATE | CELGENE CORPORATION | 2023-07-27 | — | — | US | disclosed |
| WO-2023139145-A1 | SAPONIN-BASED ADJUVANTS AND VACCINES | ASOCIACIÓN CENTRO DE INVESTIGACIÓN COOPERATIVA EN BIOCIENCIAS-CIC BIOGUNE (ES) | 2023-07-27 | — | — | WO | disclosed |
| US-20230234959-A1 | BICYCLIC UREA KINASE INHIBITORS AND USES THEREOF | THE BROAD INSTITUTE, INC. (US) | 2023-07-27 | — | — | US | disclosed |
| US-11708367-B2 | Compounds for the treatment of kinase-dependent disorders | EXELIXIS, INC. (US) | 2023-07-25 | — | — | US | disclosed |
| US-11708446-B2 | Polymers and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2023-07-25 | — | — | US | disclosed |
| US-20230227433-A9 | INHIBITORS OF CYCLIN-DEPENDENT KINASE 12 (CDK12) AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2023-07-20 | — | — | US | disclosed |
| EP-4212532-A2 | MITRAGYNINE ANALOGS AND USES THEREOF | Memorial Sloan Kettering Cancer Center (US) | 2023-07-19 | — | — | EP | disclosed |
| US-11702402-B2 | Small molecules that block proteasome-associated ubiquitin receptor RPN13 function and uses thereof | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2023-07-18 | — | — | US | disclosed |
| US-20230219991-A1 | TRITERPENE SAPONIN ANALOGUES | ADJUVANCE TECHNOLOGIES, INC. (US) | 2023-07-13 | — | — | US | disclosed |
| WO-2023133089-A1 | IONIZABLE LIPIDS FOR MULTIPLE ORGAN TARGETING | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2023-07-13 | — | — | WO | disclosed |
| US-20230220384-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-07-13 | — | — | US | disclosed |
| US-20230218632-A1 | CYCLIC SULFONAMIDE DERIVATIVES AS TRAP1 MODULATORS AND USES THEREOF | AMATHUS THERAPEUTICS, INC. (US) | 2023-07-13 | — | — | US | disclosed |
| US-20230218774-A1 | DRUG ANTIBODY CONJUGATES | PHARMA MAR, S.A. (ES) | 2023-07-13 | — | — | US | disclosed |
| US-11697640-B2 | Compounds for treating proliferative diseases | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2023-07-11 | — | — | US | disclosed |
| US-20230212195-A1 | COMPOUNDS, CONJUGATES, AND COMPOSITIONS OF EPIPOLYTHIODIKETOPIPERAZINES AND POLYTHIODIKETOPIPERAZINES AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2023-07-06 | — | — | US | disclosed |
| WO-2023130021-A1 | CHEMICALLY MODIFIED OLIGONUCLEOTIDES WITH IMPROVED DELIVERY PROPERTIES | PHIO PHARMACEUTICALS CORP. (US) | 2023-07-06 | — | — | WO | disclosed |
| WO-2023129564-A1 | DEGRADERS OF GRK2 AND USES THEREOF | CYGNAL THERAPEUTICS, INC. (US) | 2023-07-06 | — | — | WO | disclosed |
| US-20230203484-A1 | DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO | WAVE LIFE SCIENCES LTD. (SG) | 2023-06-29 | — | — | US | disclosed |
| US-20230203087-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-06-29 | — | — | US | disclosed |
| WO-2023121753-A1 | BIOMOLECULE-POLYMER-PHARMACEUTICAL AGENT CONJUGATES FOR DELIVERING THE PHARMACEUTICAL AGENT | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2023-06-29 | — | — | WO | disclosed |
| US-20230203015-A1 | MAP KINASE KINASE (MKK7) INHIBITORS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2023-06-29 | — | — | US | disclosed |
| US-20230203081-A1 | LINCOSAMIDE ANTIBIOTICS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-06-29 | — | — | US | disclosed |
| US-20230203053-A1 | HALOGENATED DERIVATIVES OF MORPHINANS AND USES THEREOF | XALUD THERAPEUTICS, INC. (US) | 2023-06-29 | — | — | US | disclosed |
| US-20230201339-A1 | USE OF THIAZOLE AMIDE COMPOUNDS FOR MODULATING HUMAN IMMUNE RESPONSE | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2023-06-29 | — | — | US | disclosed |
| WO-2023122721-A2 | PEPTIDES FOR CELL-TYPE SPECIFIC TARGETING OF THE RETINA | OREGON STATE UNIVERSITY (US) | 2023-06-29 | — | — | WO | disclosed |
| US-11684590-B2 | Substituted alkylphenols as HCN1 antagonists | CORNELL UNIVERSITY (US) | 2023-06-27 | — | — | US | disclosed |
| WO-2023114455-A1 | DISCOVERY OF PIPERLONGUMINE AS A NOVEL E3 LIGASE LIGAND | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2023-06-22 | — | — | WO | disclosed |
| US-20230192756-A1 | NEUROACTIVE STEROIDS, COMPOSITIONS, AND USES THEREOF | Sage Therapeutics, LLC | 2023-06-22 | — | — | US | disclosed |
| US-20230192610-A1 | BIOMOLECULE-POLYMER-PHARMACEUTICAL AGENT CONJUGATES FOR DELIVERING THE PHARMACEUTICAL AGENT | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2023-06-22 | — | — | US | disclosed |
| WO-2023114507-A1 | CRYSTALLINE FORM OF N-(6-AMINO-5-METHYLPYRIDIN-3-YL)-2-(BENZO[D]THIAZOL-5-YL)-5-METHYLPIPERIDIN-1-YL)-2-OXOACETAMIDE, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE THEREOF | TANGO THERAPEUTICS, INC. (US) | 2023-06-22 | — | — | WO | disclosed |
| US-20230192607-A1 | TRANSCRIPTIONAL ENHANCED ASSOCIATE DOMAIN (TEAD) TRANSCRIPTION FACTOR INHIBITORS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2023-06-22 | — | — | US | disclosed |
| WO-2023114188-A1 | IONIZABLE LIPIDS AND COMPOSITIONS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2023-06-22 | — | — | WO | disclosed |
| US-20230192679-A1 | CRYSTALLINE FORMS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE THEREOF | TANGO THERAPEUTICS, INC. | 2023-06-22 | — | — | US | disclosed |
| US-11678968-B2 | Urological device including a valve retained in a urinary catheter | COLOPLAST A/S (DK) | 2023-06-20 | — | — | US | disclosed |
| US-11679165-B2 | Alkenyl substituted 2,5-piperazinediones, compositions, and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2023-06-20 | — | — | US | disclosed |
| WO-2023107415-A1 | COMPOSITIONS COMPRISING MODIFIED PHOSPHOLIPIDS AND USES THEREOF | THE CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2023-06-15 | — | — | WO | disclosed |
| US-20230183168-A1 | IONIZABLE LIPIDS AND COMPOSITIONS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2023-06-15 | — | — | US | disclosed |
| US-20230181742-A1 | AMINE-CONTAINING TRANSFECTION REAGENTS AND METHODS FOR MAKING AND USING SAME | Life Technologies Corporation | 2023-06-15 | — | — | US | disclosed |
| WO-2023105494-A1 | CATIONIC STEROID COMPOUNDS, METHOD OF OBTAINING THEREOF, FORMULATIONS COMPRISING THEREOF AND THEIR USES | UNIVERSIDADE DO PORTO (PT) | 2023-06-15 | — | — | WO | disclosed |
| US-20230183240-A9 | INHIBITORS OF CYCLIN-DEPENDENT KINASES | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2023-06-15 | — | — | US | disclosed |
| US-20230183204-A9 | BENZIMIDAZOLE DERIVATIVES AND AZA-BENZIMIDAZOLE DERIVATIVES AS JANUS KINASE 2 INHIBITORS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2023-06-15 | — | — | US | disclosed |
| WO-2023107648-A2 | SYNTHESIS OF ESTER, CARBONATE, AND CARBAMATE-DERIVED NOVEL BIODEGRADABLE IONIZABLE LIPIDS FROM METHYL RICINOLEATE OR METHYL 12-HYDROXYSTEARATE AND ITS APPLICATIONS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2023-06-15 | — | — | WO | disclosed |
| US-11674136-B2 | DNA-templated macrocycle library | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-06-13 | — | — | US | disclosed |
| US-11673897-B2 | Compounds for the treatment of kinase-dependent disorders | EXELIXIS, INC. (US) | 2023-06-13 | — | — | US | disclosed |
| US-11673891-B2 | Imidazopyrimidine compounds and uses thereof | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2023-06-13 | — | — | US | disclosed |
| US-11673910-B2 | Macrolides with modified desosamine sugars and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2023-06-13 | — | — | US | disclosed |
| US-20230174523-A1 | BENZENESULFONAMIDE DERIVATIVES AS TRAP1 MODULATORS AND USES THEREOF | AMATHUS THERAPEUTICS, INC. (US) | 2023-06-08 | — | — | US | disclosed |
| WO-2023102024-A1 | POLY(β-AMINO ESTER) MICROPARTICLES FOR MICRONUTRIENT FORTIFICATION | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2023-06-08 | — | — | WO | disclosed |
| US-20230174576-A1 | BETA-STRAND BRIDGE PEPTIDE | KYOTO UNIVERSITY (JP) | 2023-06-08 | — | — | US | disclosed |
| WO-2023099741-A1 | SAPONIN-BASED ADJUVANTS AND VACCINES | ASOCIACIÓN CENTRO DE INVESTIGACIÓN COOPERATIVA EN BIOCIENCIAS-CIC BIOGUNE (ES) | 2023-06-08 | — | — | WO | disclosed |
| WO-2023102111-A1 | SMALL MOLECULE INHIBITORS OF REPEAT ASSOCIATED NON-AUG (RAN) TRANSLATION AND COMBINATION THERAPIES | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2023-06-08 | — | — | WO | disclosed |
| EP-4188920-A1 | PIPERIDIN-1-YL-N-PYRYDINE-3-YL-2-OXOACETAMIDE DERIVATIVES USEFUL FOR THE TREATMENT OF MTAP-DEFICIENT AND/OR MTA-ACCUMULATING CANCERS | Tango Therapeutics, Inc. (US) | 2023-06-07 | — | — | EP | disclosed |
| EP-4190359-A1 | SAPONIN-BASED ADJUVANTS AND VACCINES | Asociación Centro de Investigación Cooperativa en Biociencias - CIC bioGUNE (ES) | 2023-06-07 | — | — | EP | disclosed |
| US-20230167081-A1 | 5-AMINO-2-PIPERIDINON-3-YL-1-OXOISOINDOLINE DERIVATIVES FOR DEGRADATION OF IKZF2 DEGRADERS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-06-01 | — | — | US | disclosed |
| WO-2023096904-A2 | C-16 MODIFIED TRIOXACARCINS, ANTIBODY DRUG CONJUGATES, AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-06-01 | — | — | WO | disclosed |
| EP-4185284-A1 | AMINO ACIDS | Fog Pharmaceuticals, Inc. (US) | 2023-05-31 | — | — | EP | disclosed |
| EP-4185599-A2 | STAPLED PEPTIDES AND METHODS THEREOF | Fog Pharmaceuticals, Inc. (US) | 2023-05-31 | — | — | EP | disclosed |
| US-11660354-B2 | Inhibitor-functionalized ultrasmall nanoparticles and methods thereof | MEMORIAL SLOAN KETTERING CANCER CENTER (US) | 2023-05-30 | — | — | US | disclosed |
| US-20230158159-A1 | CHIMERIC DEGRADERS OF CYCLIN-DEPENDENT KINASE 9 AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2023-05-25 | — | — | US | disclosed |
| US-20230159509-A1 | PYRIDINESULFONAMIDE DERIVATIVES AS TRAP1 MODULATORS AND USES THEREOF | AMATHUS THERAPEUTICS, INC. (US) | 2023-05-25 | — | — | US | disclosed |
| WO-2023083343-A1 | POLYCYCLIC COMPOUNDS AND METHODS THEREOF | HEPAITECH (BEIJING) BIOPHARMA TECHNOLOGY CO., LTD. (CN) | 2023-05-19 | — | — | WO | disclosed |
| US-20230151001-A9 | IMIDAZOPYRIDINE DERIVATIVES AND AZA-IMIDAZOPYRIDINE DERIVATIVES AS JANUS KINASE 2 INHIBITORS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2023-05-18 | — | — | US | disclosed |
| US-20230150921-A1 | PHENOLIC ACID LIPID BASED CATIONIC LIPIDS | TRANSLATE BIO, INC. (US) | 2023-05-18 | — | — | US | disclosed |
| US-20230145795-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-05-11 | — | — | US | disclosed |
| WO-2023081120-A1 | CONTACT LENS WITH OPTICAL PROPHYLAXIS | HIGH PERFORMANCE OPTICS, INC. (US) | 2023-05-11 | — | — | WO | disclosed |
| US-20230147502-A1 | PHOSPHONATE LINKERS AND THEIR USE TO FACILIATE CELLULAR RETENTION OF COMPOUNDS | MERCK SHARP & DOHME LLC (US) | 2023-05-11 | — | — | US | disclosed |
| WO-2023081141-A1 | THYMIDYLATE SYNTHASE INHIBITORS AND USES THEREOF | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2023-05-11 | — | — | WO | disclosed |
| US-20230148448-A9 | BENZOTHIAZOLE DERIVATIVES AND 7-AZA-BENZOTHIAZOLE DERIVATIVES AS JANUS KINASE 2 INHIBITORS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2023-05-11 | — | — | US | disclosed |
| WO-2023081505-A1 | ADJUVANT COMPOUNDS AND FORMULATIONS | ADJUVANCE TECHNOLOGIES, INC. (US) | 2023-05-11 | — | — | WO | disclosed |
| EP-2753632-B1 | NEUROACTIVE STEROIDS, COMPOSITIONS, AND USES THEREOF | SAGE THERAPEUTICS INC (US) | 2023-05-10 | — | — | EP | disclosed |
| EP-3653230-B1 | COMPOSITIONS, METHODS AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS | LANTHEUS MEDICAL IMAGING INC (US) | 2023-05-10 | — | — | EP | disclosed |
| US-11643657-B2 | Chiral control | WAVE LIFE SCIENCES LTD. (SG) | 2023-05-09 | — | — | US | disclosed |
| US-20230138968-A1 | CONTACT LENS WITH OPTICAL PROPHYLAXIS | HIGH PERFORMANCE OPTICS, INC. (US) | 2023-05-04 | — | — | US | disclosed |
| WO-2023076352-A2 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-05-04 | — | — | WO | disclosed |
| US-20230135188-A1 | FE/CU-MEDIATED KETONE SYNTHESIS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-05-04 | — | — | US | disclosed |
| WO-2023075766-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-05-04 | — | — | WO | disclosed |
| EP-3273966-B1 | INHIBITORS OF CYCLIN-DEPENDENT KINASES | DANA FARBER CANCER INST INC (US) | 2023-05-03 | — | — | EP | disclosed |
| US-11638705-B2 | 4(1H)-quinolone derivatives and uses thereof | ACADEMIA SINICA (TW) | 2023-05-02 | — | — | US | disclosed |
| WO-2023067132-A1 | ANTITUMORAL COMPOUNDS | PHARMA MAR, S.A. (ES) | 2023-04-27 | — | — | WO | disclosed |
| WO-2023069495-A1 | OLIGONUCLEOTIDES WITH 2'-DEOXY-2'-F-2'-C-METHYL NUCLEOTIDES | ALNYLAM PHARMACEUTICALS, INC. (US) | 2023-04-27 | — | — | WO | disclosed |
| US-20230132377-A9 | OLIGONUCLEOTIDES CONJUGATES COMPRISING 7'-5'-ALPHA-ANOMERIC-BICYCLIC SUGAR NUCLEOSIDES | ALPHA ANOMERIC SAS (FR) | 2023-04-27 | — | — | US | disclosed |
| US-20230128195-A1 | SYNTHESIS OF HALICHONDRINS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-04-27 | — | — | US | disclosed |
| US-20230132397-A9 | USE OF TOLL-LIKE RECEPTOR 2 (TLR-2) AGONIST FOR MODULATING HUMAN IMMUNE RESPONSE | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2023-04-27 | — | — | US | disclosed |
| US-20230128688-A1 | DIRECTED CONJUGATION TECHNOLOGIES | KLEO PHARMACEUTICALS, INC. | 2023-04-27 | — | — | US | disclosed |
| US-20230128815-A1 | ADJUVANT COMPOUNDS, SALT FORMS, AND FORMULATIONS | ADJUVANCE TECH INC (US) | 2023-04-27 | — | — | US | disclosed |
| US-20230131867-A1 | TRITERPENE SAPONINS, METHODS OF SYNTHESIS AND USES THEREOF | SLOAN KETTERING INST CANCER RES (US) | 2023-04-27 | — | — | US | disclosed |
| EP-4169924-A2 | SYNTHESIS OF HALICHONDRINS | President And Fellows Of Harvard College (US) | 2023-04-26 | — | — | EP | disclosed |
| US-11634449-B2 | Macrolides and methods of their preparation and use | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-04-25 | — | — | US | disclosed |
| US-11634408-B2 | Aryl hydrocarbon receptor modulators and uses thereof | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. (US) | 2023-04-25 | — | — | US | disclosed |
| US-11634450-B2 | DOT1L degraders and uses thereof | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2023-04-25 | — | — | US | disclosed |
| US-11634710-B2 | Oligonucleotide compositions and methods thereof | WAVE LIFE SCIENCES LTD. (SG) | 2023-04-25 | — | — | US | disclosed |
| WO-2023064343-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | VANQUA BIO, INC. (US) | 2023-04-20 | — | — | WO | disclosed |
| WO-2023064345-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | VANQUA BIO, INC. (US) | 2023-04-20 | — | — | WO | disclosed |
| US-20230117680-A1 | CYCLOPHILIN D INHIBITORS AND USES THEREOF | THE BROAD INSTITUTE, INC. (US) | 2023-04-20 | — | — | US | disclosed |
| US-20230124955-A1 | AMINO ACID-, PEPTIDE- AND POLYPEPTIDE-LIPIDS, ISOMERS, COMPOSITIONS, AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2023-04-20 | — | — | US | disclosed |
| EP-3416958-B1 | THIOSEMICARBAZIDES AS ANTIFUNGAL COMPOUNDS AND THEIR USES | DANA FARBER CANCER INST INC (US) | 2023-04-19 | — | — | EP | disclosed |
| EP-4164752-A1 | INHIBITORS OF TRANSCRIPTIONAL ENHANCED ASSOCIATE DOMAIN (TEAD) AND USES THEREOF | Dana-Farber Cancer Institute, Inc. (US) | 2023-04-19 | — | — | EP | disclosed |
| EP-3310764-B1 | ALKENYL SUBSTITUTED 2,5-PIPERAZINEDIONES AND THEIR USE IN COMPOSITIONS FOR DELIVERING AN AGENT TO A SUBJECT OR CELL | MASSACHUSETTS INST TECHNOLOGY (US) | 2023-04-19 | — | — | EP | disclosed |
| US-11629162-B2 | Triterpene saponin variants, methods of synthesis and use thereof | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2023-04-18 | — | — | US | disclosed |
| US-20230113778-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. | 2023-04-13 | — | — | US | disclosed |
| WO-2023059806-A1 | LIPID NANOPARTICLES FOR DRUG DELIVERY TO MICROGLIA IN THE BRAIN | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2023-04-13 | — | — | WO | disclosed |
| US-20230114207-A1 | THE COMBINATION OF CYCLIN DEPENDENT KINASE 7 INHIBITOR AND IMMUNOTHERAPY FOR TREATMENT OF CANCER | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2023-04-13 | — | — | US | disclosed |
| US-20230116686-A1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | OXFORD FINANCE LLC | 2023-04-13 | — | — | US | disclosed |
| EP-4161651-A1 | QUINAZOLINE-DERIVED HCK INHIBITORS FOR USE IN THE TREATMENT OF MYD88 MUTATED DISEASES | Dana-Farber Cancer Institute, Inc. (US) | 2023-04-12 | — | — | EP | disclosed |
| US-20230109357-A1 | 14-MEMBERED KETOLIDES AND METHODS OF THEIR PREPARATION AND USE | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-04-06 | — | — | US | disclosed |
| WO-2023053059-A1 | ANTIFOULING COMPOUND, METHOD AND USES THEREOF | UNIVERSIDADE DO PORTO (PT) | 2023-04-06 | — | — | WO | disclosed |
| US-20230095276-A1 | ESTERS OF A RETINOID AND A TOCOPHEROL OR TERT-BUTYLHYDROQUINONE AND PREPARATIONS THEREOF | CONAGEN INC. (US) | 2023-03-30 | — | — | US | disclosed |
| WO-2023049475-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-03-30 | — | — | WO | disclosed |
| WO-2023049218-A1 | DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO | WAVE LIFE SCIENCES LTD. (SG) | 2023-03-30 | — | — | WO | disclosed |
| WO-2023049477-A2 | COMPOSITIONS FOR EDITING MECP2 TRANSCRIPTS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-03-30 | — | — | WO | disclosed |
| WO-2023049493-A1 | THIOPHENE-BASED LIPIDS | OREGON STATE UNIVERSITY (US) | 2023-03-30 | — | — | WO | disclosed |
| US-20230094076-A1 | COMBINATION THERAPY | GLAXOSMITHKLINE IP DEV LTD (GB) | 2023-03-30 | — | — | US | disclosed |
| WO-2023049438-A1 | GRK2 INHIBITORS AND USES THEREOF | SONATA THERAPEUTICS, INC. (US) | 2023-03-30 | — | — | WO | disclosed |
| EP-4153747-A2 | DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO | Wave Life Sciences Ltd. (SG) | 2023-03-29 | — | — | EP | disclosed |
| EP-4153604-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | Wave Life Sciences Ltd. (SG) | 2023-03-29 | — | — | EP | disclosed |
| US-20230089478-A1 | CHEMICALLY MODIFIED OLIGONUCLEOTIDES WITH IMPROVED SYSTEMIC DELIVERY | PHIO PHARMACEUTICALS CORP. (US) | 2023-03-23 | — | — | US | disclosed |
| US-20230089442-A1 | TECHNOLOGIES USEFUL FOR OLIGONUCLEOTIDE PREPARATION | WAVE LIFE SCIENCES LTD. (SG) | 2023-03-23 | — | — | US | disclosed |
| US-20230093692-A1 | C10-Alkylene Substituted 13-Membered Macrolides and Uses Thereof | ZIKANI THERAPEUTICS, INC. | 2023-03-23 | — | — | US | disclosed |
| EP-3615544-B1 | ANTITUMORAL COMPOUNDS | PHARMA MAR SA (ES) | 2023-03-22 | — | — | EP | disclosed |
| US-11608412-B2 | Polymer-lipids and compositions | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2023-03-21 | — | — | US | disclosed |
| WO-2023035913-A1 | METHODS OF TREATING CNS DISORDERS | HANGZHOU HIGHLIGHTLL PHARMACEUTICAL CO., LTD (CN) | 2023-03-16 | — | — | WO | disclosed |
| EP-3389669-B1 | TRITERPENE SAPONIN VARIANTS, METHODS OF SYNTHESIS AND USE THEREOF | MEMORIAL SLOAN KETTERING CANCER CENTER (US) | 2023-03-15 | — | — | EP | disclosed |
| US-11603532-B2 | Oligonucleotide compositions and methods of use thereof | WAVE LIFE SCIENCES LTD. (SG) | 2023-03-14 | — | — | US | disclosed |
| US-11603349-B2 | Anti-fibrotic compounds | CERTA THERAPEUTICS PTY LTD (AU) | 2023-03-14 | — | — | US | disclosed |
| WO-2022155418-A9 | MODIFIED OLIGONUCLEOTIDES | ALNYLAM PHARMACEUTICALS, INC. (US) | 2023-03-09 | — | — | WO | disclosed |
| EP-4047002-B1 | ANTITUMORAL COMPOUNDS | PHARMA MAR SA (ES) | 2023-03-08 | — | — | EP | disclosed |
| US-11596691-B2 | Photoswitchable HDAC inhibitors | THE GENERAL HOSPITAL CORPORATION (US) | 2023-03-07 | — | — | US | disclosed |
| US-20230060499-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. | 2023-03-02 | — | — | US | disclosed |
| US-20230068959-A1 | BRANCHED MULTI-FUNCTIONAL MACROMONOMERS AND RELATED POLYMERS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2023-03-02 | — | — | US | disclosed |
| EP-4139275-A1 | COMPOUNDS AND PHARMACEUTICAL USES THEREOF | Syneurx International (Taiwan) Corp. (TW) | 2023-03-01 | — | — | EP | disclosed |
| EP-4138923-A1 | DRUG ANTIBODY CONJUGATES | Pharma Mar, S.A. (ES) | 2023-03-01 | — | — | EP | disclosed |
| US-20230058545-A1 | HCK AS A THERAPEUTIC TARGET IN MYD88 MUTATED DISEASES | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2023-02-23 | — | — | US | disclosed |
| US-20230054084-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. | 2023-02-23 | — | — | US | disclosed |
| WO-2023023044-A1 | ESTERS OF A RETINOID AND TOCOPHEROL OR TERT-BUTYLHYDROQUINONE AND PREPARATIONS THEREOF | CONAGEN INC. (US) | 2023-02-23 | — | — | WO | disclosed |
| EP-4137572-A1 | CHIRAL DESIGN | Wave Life Sciences Ltd. (SG) | 2023-02-22 | — | — | EP | disclosed |
| EP-3498701-B1 | PRMT5 INHIBITORS AND USES THEREOF | EPIZYME INC (US) | 2023-02-22 | — | — | EP | disclosed |
| US-11584933-B2 | RNA interference in ocular indications | PHIO PHARMACEUTICALS CORP. (US) | 2023-02-21 | — | — | US | disclosed |
| US-11584727-B2 | 2-thioxothiazolidin-4-one derivatives active as transthyretin ligands and uses thereof | BSIM THERAPEUTICS, S.A. (PT) | 2023-02-21 | — | — | US | disclosed |
| US-20230047178-A1 | HETEROARYL COMPOUNDS AND USES THEREOF | APRINOIA THERAPEUTICS INC. (CN) | 2023-02-16 | — | — | US | disclosed |
| WO-2023018954-A1 | TREATMENT OF JAK-INHIBITION-RESPONSIVE DISORDERS WITH PRODRUGS OF JAK INHIBITORS | CONCERT PHARMACEUTICALS, INC. (US) | 2023-02-16 | — | — | WO | disclosed |
| US-20230043835-A1 | Compounds for the Treatment of Kinase-Dependent Disorders | EXELIXIS, INC. | 2023-02-09 | — | — | US | disclosed |
| WO-2023015264-A1 | IMMUNOTHERAPY OF CANCER UTILIZING NATURAL KILLER CELLS TREATED WITH CHEMICALLY MODIFIED OLIGONUCLEOTIDES | PHIO PHARMACEUTICALS CORP. (US) | 2023-02-09 | — | — | WO | disclosed |
| EP-4125893-A1 | TECHNOLOGIES FOR PREVENTING OR TREATING INFECTIONS | Biohaven Therapeutics Ltd. (US) | 2023-02-08 | — | — | EP | disclosed |
| EP-4125989-A1 | VIRAL ENTRY INHIBITORS AND RNA POLYMERASE INHIBITORS | Selva Therapeutics, Inc. (US) | 2023-02-08 | — | — | EP | disclosed |
| EP-4126813-A1 | PHENOLIC ACID LIPID BASED CATIONIC LIPIDS | Translate Bio, Inc. (US) | 2023-02-08 | — | — | EP | disclosed |
| WO-2023009475-A1 | ROCK2 INHIBITORS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-02-02 | — | — | WO | disclosed |
| US-11566039-B2 | Lincosamide antibiotics and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-01-31 | — | — | US | disclosed |
| US-20230028880-A1 | CD38-BINDING AGENTS AND USES THEREOF | KLEO PHARMACEUTICALS, INC. | 2023-01-26 | — | — | US | disclosed |
| US-20230023124-A1 | CANCER TREATMENTS TARGETING CANCER STEM CELLS | REMEDY PLAN, INC. (US) | 2023-01-26 | — | — | US | disclosed |
| US-20230028318-A1 | FLUOROGENIC AMINO ACIDS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-01-26 | — | — | US | disclosed |
| US-20230022913-A1 | CONJUGATES OF TUMOR NECROSIS FACTOR INHIBITORS TO FUNCTIONALIZED POLYMERS | FISH & RICHARDSON PC | 2023-01-26 | — | — | US | disclosed |
| EP-4121030-A1 | PYRIDINESULFONAMIDE DERIVATIVES AS TRAP1 MODULATORS AND USES THEREOF | Amathus Therapeutics, Inc. (US) | 2023-01-25 | — | — | EP | disclosed |
| EP-4121029-A1 | BENZENESULFONAMIDE DERIVATIVES AS TRAP1 MODULATORS AND USES THEREOF | Amathus Therapeutics, Inc. (US) | 2023-01-25 | — | — | EP | disclosed |
| EP-4121072-A1 | CYCLIC SULFONAMIDE DERIVATIVES AS TRAP1 MODULATORS AND USES THEREOF | Amathus Therapeutics, Inc. (US) | 2023-01-25 | — | — | EP | disclosed |
| EP-4121082-A1 | HELICAL STAPLED PEPTIDES AND USES THEREOF | Fog Pharmaceuticals, Inc. (US) | 2023-01-25 | — | — | EP | disclosed |
| US-20230016686-A1 | MACROCYCLIC COMPOUNDS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-01-19 | — | — | US | disclosed |
| WO-2023288045-A2 | SIMPLE CHEMICAL APPROACHES TO INTRODUCE 2,6-DIAMINOPURINE AND 2-AMINOADENINE CONJUGATES INTO OLIGONUCLEOTIDES | ALNYLAM PHARMACEUTICALS, INC. (US) | 2023-01-19 | — | — | WO | disclosed |
| US-20230012681-A1 | ANTIBODY DRUG CONJUGATES COMPRISING ECTEINASCIDIN DERIVATIVES | PHARMA MAR, S.A. (ES) | 2023-01-19 | — | — | US | disclosed |
| WO-2023288047-A2 | MULTIPLEXING TARGETING LIGANDS THROUGH CLICK CHEMISTRY AT THE ANOMERIC SITE OF SUGARS | ALNYLAM PHARMACEUTICALS, INC. (US) | 2023-01-19 | — | — | WO | disclosed |
| WO-2023287931-A1 | ESTERS OF A RETINOID AND BAKUCHIOL AND PREPARATIONS THEREOF | CONAGEN INC. (US) | 2023-01-19 | — | — | WO | disclosed |
| WO-2023288257-A2 | BIOCATALYTIC COUPLING REACTIONS TOWARD REGIOSELECTIVELY ENRICHED SUBSTITUTED PYRAZINES | CONAGEN INC. (US) | 2023-01-19 | — | — | WO | disclosed |
| WO-2023285627-A1 | AN AMINOSQUARAMIDE POLYMER | UNIVERSITAT DE LES ILLES BALEARS (ES) | 2023-01-19 | — | — | WO | disclosed |
| US-11554172-B2 | Phosphonate linkers and their use to facilitate cellular retention of compounds | MERCK SHARP & DOHME LLC (US) | 2023-01-17 | — | — | US | disclosed |
| US-20230010562-A1 | 4,9-DIOXO-4,9-DIHYDRONAPHTHO[2,3-B]FURAN-3-CARBOXAMIDE DERIVATIVES AND USES THEREOF FOR TREATING PROLIFERATIVE DISEASES AND INFECTIOUS DISEASES | ACADEMIA SINICA (TW) | 2023-01-12 | — | — | US | disclosed |
| WO-2023283434-A1 | AMINOOXY CLICK CHEMISTRY (AOCC): A VERSATILE BIOCONJUGATION APPROACH | ALNYLAM PHARMACEUTICALS, INC. (US) | 2023-01-12 | — | — | WO | disclosed |
| US-11548898-B2 | Synthesis of halichondrins | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-01-10 | — | — | US | disclosed |
| US-20230002766-A1 | CHEMICALLY MODIFIED OLIGONUCLEOTIDES TARGETING BROMODOMAIN CONTAINING PROTEIN 4 (BRD4) FOR IMMUNOTHERAPY | PHIO PHARMACEUTICALS CORP. (US) | 2023-01-05 | — | — | US | disclosed |
| WO-2023278754-A1 | COMPOSITIONS FOR DELIVERY OF MRNA | TRANSLATE BIO, INC. (US) | 2023-01-05 | — | — | WO | disclosed |
| WO-2023278698-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2023-01-05 | — | — | WO | disclosed |
| EP-4110773-A1 | MAP KINASE KINASE (MKK7) INHIBITORS AND USES THEREOF | Dana-Farber Cancer Institute, Inc. (US) | 2023-01-04 | — | — | EP | disclosed |
| EP-3359573-B1 | LABELING OF ANTIBODIES | THE WHITEHEAD INSTITUTE FOR BIOMEDICAL RES (US) | 2023-01-04 | — | — | EP | disclosed |
| US-11542259-B2 | Compounds for the treatment of kinase-dependent disorders | EXELIXIS, INC. (US) | 2023-01-03 | — | — | US | disclosed |
| WO-2022271557-A1 | PROCESSES FOR THE PREPARATION OF (S)-2-(2,6-DIOXOPIPERIDIN-3-YL)-4-((2-FLUORO-4-((3-MORPHOLINOAZETIDIN-1-YL) METHYL)BENZYL) AMINO)ISOINDOLINE-1,3-DIONE | CELGENE CORPORATION (US) | 2022-12-29 | — | — | WO | disclosed |
| US-20220411426-A1 | SUBSTRATE SELECTIVE INHIBITORS OF INSULIN-DEGRADING ENZYME (IDE) AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2022-12-29 | — | — | US | disclosed |
| EP-3649135-B1 | SYNTHESIS OF HALICHONDRINS | HARVARD COLLEGE (US) | 2022-12-28 | — | — | EP | disclosed |
| US-11535706-B2 | Polycarbonate polyol compositions and methods | SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) | 2022-12-27 | — | — | US | disclosed |
| US-11535643-B2 | Macrolides with modified desosamine sugars and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2022-12-27 | — | — | US | disclosed |
| US-11535634-B2 | Compounds, conjugates, and compositions of epipolythiodiketopiperazines and polythiodiketopiperazines and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2022-12-27 | — | — | US | disclosed |
| WO-2022263927-A2 | PLASMALOGEN DERIVATIVES AND USES THEREOF | PHOSKA BIOPHARMA PTE. LTD. (SG) | 2022-12-22 | — | — | WO | disclosed |
| US-20220401467-A1 | OLIGONUCLEOTIDES, COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2022-12-22 | — | — | US | disclosed |
| US-20220402869-A1 | TRANSCRIPTIONAL ENHANCED ASSOCIATE DOMAIN (TEAD) TRANSCRIPTION FACTOR INHIBITORS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2022-12-22 | — | — | US | disclosed |
| EP-3870234-B1 | ANTIBODY DRUG CONJUGATES COMPRISING ECTEINASCIDIN DERIVATIVES | PHARMA MAR SA (ES) | 2022-12-21 | — | — | EP | disclosed |
| EP-2872147-B1 | METHOD FOR MAKING CHIRAL OLIGONUCLEOTIDES | WAVE LIFE SCIENCES LTD (SG) | 2022-12-21 | — | — | EP | disclosed |
| US-11530250-B2 | Tyrosine-specific functionalized insulin and insulin analogs | MERCK SHARP & DOHME LLC (US) | 2022-12-20 | — | — | US | disclosed |
| WO-2022261257-A1 | STAPLED PEPTIDES AND METHODS THEREOF | FOG PHARMACEUTICALS, INC. (US) | 2022-12-15 | — | — | WO | disclosed |
| US-20220395509-A1 | A PYRAZOLOPYRIMIDINE DERIVATIVE AS A HCK INHIBITOR FOR USE IN THERAPY, IN PARTICULAR MYD88 MUTATED DISEASES | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2022-12-15 | — | — | US | disclosed |
| EP-4101855-A1 | ANTITUMORAL COMPOUNDS | Pharma Mar S.A. (ES) | 2022-12-14 | — | — | EP | disclosed |
| WO-2022256480-A1 | ARYLCOUMARIN SYNTHESIS WITH AZEOTROPIC REMOVAL OF WATER | CONAGEN INC. (US) | 2022-12-08 | — | — | WO | disclosed |
| WO-2022256399-A2 | LATENT-FLUORIDE CONTAINING POLYMERS FOR TRIGGERED DEGRADATION | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2022-12-08 | — | — | WO | disclosed |
| US-20220378782-A1 | KCC2 EXPRESSION ENHANCING COMPOUNDS AND USES THEREOF | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2022-12-01 | — | — | US | disclosed |
| EP-4095146-A1 | MACROLIDES AND METHODS OF THEIR PREPARATION AND USE | President And Fellows Of Harvard College (US) | 2022-11-30 | — | — | EP | disclosed |
| US-11512053-B2 | Arginine methyltransferase inhibitors and uses thereof | Epizyme, Inc. (US) | 2022-11-29 | — | — | US | disclosed |
| US-11510989-B2 | Conjugates of biologically active molecules to functionalized polymers | QUIAPEG PHARMACEUTICALS AB (SE) | 2022-11-29 | — | — | US | disclosed |
| US-20220370628-A9 | BRUSH PRODRUGS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2022-11-24 | — | — | US | disclosed |
| WO-2022246086-A1 | ANTIBODY DRUG CONJUGATES USING MATES TECHNOLOGY FOR DELIVERING CYTOTOXIC AGENTS | BIOHAVEN THERAPEUTICS LTD. (US) | 2022-11-24 | — | — | WO | disclosed |
| US-20220372075-A1 | STAPLED AND STITCHED POLYPEPTIDES AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2022-11-24 | — | — | US | disclosed |
| US-20220372017-A1 | HCK DEGRADERS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2022-11-24 | — | — | US | disclosed |
| EP-4090374-A1 | MACROMOLECULAR PRODRUGS FOR LIGHT-EMITTING DIODES AND USES THEREOF | Children's Medical Center Corporation (US) | 2022-11-23 | — | — | EP | disclosed |
| US-11505522-B2 | Processes for the preparation of (S)-tert-butyl 4,5- diamino-5-oxopentanoate | CELGENE CORPORATION (US) | 2022-11-22 | — | — | US | disclosed |
| US-11505556-B2 | Halogenated derivatives of morphinans and uses thereof | XALUD THERAPEUTICS, INC. (US) | 2022-11-22 | — | — | US | disclosed |
| US-11504369-B2 | Cytosine-based TET enzyme inhibitors | PRESIDENT AND TRUSTEES OF BATES COLLEGE (US) | 2022-11-22 | — | — | US | disclosed |
| WO-2022241257-A1 | NAMPT INHBITORS AND USES THEREOF | REMEDY PLAN, INC. (US) | 2022-11-17 | — | — | WO | disclosed |
| WO-2022240978-A1 | MACROCYCLIC COMPOUNDS AND USES THEREOF | THESEUS PHARMACEUTICALS, INC. (US) | 2022-11-17 | — | — | WO | disclosed |
| EP-3468944-B1 | CO-CRYSTALS OF SODIUM BENZOATE AND USES THEREOF | SYNEURX INT TAIWAN CORP (TW) | 2022-11-16 | — | — | EP | disclosed |
| US-11498892-B2 | Fe/Cu-mediated ketone synthesis | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2022-11-15 | — | — | US | disclosed |
| EP-4085136-A1 | CHEMICALLY MODIFIED OLIGONUCLEOTIDES WITH IMPROVED SYSTEMIC DELIVERY | Phio Pharmaceuticals Corp. (US) | 2022-11-09 | — | — | EP | disclosed |
| US-11491228-B2 | Hydrogels and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2022-11-08 | — | — | US | disclosed |
| US-11492350-B2 | Compounds and methods of use | TANGO THERAPEUTICS, INC. (US) | 2022-11-08 | — | — | US | disclosed |
| US-20220348563-A1 | KDM INHIBITORS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2022-11-03 | — | — | US | disclosed |
| US-20220347099-A1 | LIPID FORMULATIONS FOR DELIVERY OF MESSENGER RNA | TRANSLATE BIO, INC. | 2022-11-03 | — | — | US | disclosed |
| WO-2022232088-A1 | TRANSCRIPTIONAL ENHANCED ASSOCIATED DOMAIN (TEAD) TRANSCRIPTION FACTOR INHIBITORS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2022-11-03 | — | — | WO | disclosed |
| WO-2022232383-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | VANQUA BIO, INC. (US) | 2022-11-03 | — | — | WO | disclosed |
| WO-2022232259-A1 | SOLUBLE ADENYLYL CYCLASE (SAC) INHIBITORS AND USES THEREOF | CORNELL UNIVERSITY (US) | 2022-11-03 | — | — | WO | disclosed |
| US-20220348590-A1 | CYCLOOXYGENASE-2 INHIBITORS AND USES THEREOF | THE BOARD INSTITUTE, INC. (US) | 2022-11-03 | — | — | US | disclosed |
| WO-2022232360-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | VANQUA BIO, INC. (US) | 2022-11-03 | — | — | WO | disclosed |
| EP-4081527-A1 | THE COMBINATION OF CYCLIN DEPENDENT KINASE 7 INHIBITOR AND IMMUNOTHERAPY FOR TREATMENT OF CANCER | Dana-Farber Cancer Institute, Inc. (US) | 2022-11-02 | — | — | EP | disclosed |
| EP-4081202-A1 | TRANSCRIPTIONAL ENHANCED ASSOCIATE DOMAIN (TEAD) TRANSCRIPTION FACTOR INHIBITORS AND USES THEREOF | Dana-Farber Cancer Institute, Inc. (US) | 2022-11-02 | — | — | EP | disclosed |
| WO-2022225918-A1 | IMPROVED COMPOSITIONS FOR DELIVERY OF MRNA | TRANSLATE BIO, INC. (US) | 2022-10-27 | — | — | WO | disclosed |
| WO-2022226133-A1 | MULTIFACETED APPROACH TO NOVEL INTERLEUKIN-6 INHIBITORS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2022-10-27 | — | — | WO | disclosed |
| US-20220340557-A1 | ANTI-PARASITIC COMPOUNDS AND USES THEREOF | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2022-10-27 | — | — | US | disclosed |
| US-20220339303-A1 | COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS | LANTHEUS MEDICAL IMAGING, INC. | 2022-10-27 | — | — | US | disclosed |
| US-20220340983-A1 | SYSTEMS AND ASSAYS FOR IDENTIFYING PU.1 INHIBITORS | MASSACHUSTTS INSTITUTE OF TECHNOLOGY (US) | 2022-10-27 | — | — | US | disclosed |
| EP-4077404-A1 | HYALURONIC ACID DERIVATIVES | Massachusetts Institute of Technology (US) | 2022-10-26 | — | — | EP | disclosed |
| WO-2022221688-A1 | \"GOOD\"BUFFER-BASED CATIONIC LIPIDS | TRANSLATE BIO, INC. (US) | 2022-10-20 | — | — | WO | disclosed |
| WO-2022221413-A2 | E3 LIGASE BINDERS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2022-10-20 | — | — | WO | disclosed |
| WO-2022221393-A1 | VACCINES | ADJUVANCE TECHNOLOGIES, INC. (US) | 2022-10-20 | — | — | WO | disclosed |
| US-20220332747-A1 | MACROLIDES AND METHODS OF THEIR PREPARATION AND USE | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2022-10-20 | — | — | US | disclosed |
| EP-4074694-A1 | AMINO ACID-, PEPTIDE- AN POLYPEPTIDE-LIPIDS, ISOMERS, COMPOSITIONS, AN USES THEREOF | Massachusetts Institute Of Technology (US) | 2022-10-19 | — | — | EP | disclosed |
| EP-4073085-A1 | CYCLOPHILIN D INHIBITORS AND USES THEREOF | The Broad Institute Inc. (US) | 2022-10-19 | — | — | EP | disclosed |
| CN-113226377-B | Antibody drug conjugates comprising an eltrinastine derivative | 法马马有限公司 | 2022-10-18 | — | — | CN | disclosed |
| WO-2022217117-A1 | ENZYMATIC SYNTHESIS OF MYCOSPORINE-LIKE AMINO ACIDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2022-10-13 | — | — | WO | disclosed |
| US-20220324842-A1 | CANCER TREATMENTS TARGETING CANCER STEM CELLS | REMEDY PLAN, INC. (US) | 2022-10-13 | — | — | US | disclosed |
| US-11466046-B2 | 14-membered ketolides and methods of their preparation and use | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2022-10-11 | — | — | US | disclosed |
| US-11464863-B2 | Amine-containing transfection reagents and methods for making and using same | Life Technologies Corporation (US) | 2022-10-11 | — | — | US | disclosed |
| WO-2022212442-A1 | SYNTHESIS OF TRINUCLEOTIDE AND TETRANUCLEOTIDE CAPS FOR MRNA PRODUCTION | MODERNATX, INC. (US) | 2022-10-06 | — | — | WO | disclosed |
| EP-3313530-B1 | 4,6-PYRIMIDINYLENE DERIVATIVES AND USES THEREOF | DANA FARBER CANCER INST INC (US) | 2022-10-05 | — | — | EP | disclosed |
| US-11458158-B2 | Amino acid-, peptide- and polypeptide-lipids, isomers, compositions, and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2022-10-04 | — | — | US | disclosed |
| CN-109265400-B | Arginine methyltransferase inhibitors and uses thereof | EPIZYME股份有限公司 | 2022-10-04 | — | — | CN | disclosed |
| US-11459304-B2 | Ionizable lipidoids and their uses | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2022-10-04 | — | — | US | disclosed |
| US-20220305016-A1 | USES OF SALT-INDUCIBLE KINASE (SIK) INHIBITORS FOR TREATING OSTEOPOROSIS | THE GENERAL HOSPITAL CORPORATION (US) | 2022-09-29 | — | — | US | disclosed |
| US-20220306673-A1 | Macrolides with Modified Desosamine Sugars and Uses Thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2022-09-29 | — | — | US | disclosed |
| US-20220306573-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2022-09-29 | — | — | US | disclosed |
| US-20220306708-A1 | BIFUNCTIONAL STAPLED POLYPEPTIDES AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2022-09-29 | — | — | US | disclosed |
| WO-2022204544-A1 | MACROCYCLIC EGFR INHIBITORS FOR THE TREATMENT OF CANCER | THESEUS PHARMACEUTICALS, INC. (US) | 2022-09-29 | — | — | WO | disclosed |
| EP-4061425-A1 | DIRECTED CONJUGATION TECHNOLOGIES | Kleo Pharmaceuticals, Inc. (US) | 2022-09-28 | — | — | EP | disclosed |
| WO-2022197892-A1 | PURINE DERIVATIVES AS ANTICANCER AGENTS | TANGO THERAPEUTICS, INC. (US) | 2022-09-22 | — | — | WO | disclosed |
| EP-4058501-A1 | FUNCTIONAL OLIGOMERS AND FUNCTIONAL POLYMERS INCLUDING HYDROXYLATED POLYMERS AND CONJUGATES THEREOF AND USES THEREOF | Massachusetts Institute of Technology (US) | 2022-09-21 | — | — | EP | disclosed |
| US-11447515-B2 | Triterpene saponins, methods of synthesis and uses thereof | SLOAN KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2022-09-20 | — | — | US | disclosed |
| US-20220289689-A1 | 3-SUBSTITUTED PHENAZINE DERIVATIVES AS ANTIMICROBIAL AGENTS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED | 2022-09-15 | — | — | US | disclosed |
| US-20220289750-A1 | HIMASTATIN DERIVATIVES, AND PROCESSES OF PREPARATION THEREOF, AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2022-09-15 | — | — | US | disclosed |
| EP-4055167-A2 | CHEMICALLY MODIFIED OLIGONUCLEOTIDES TARGETING BROMODOMAIN CONTAINING PROTEIN 4 (BRD4) FOR IMMUNOTHERAPY | Phio Pharmaceuticals Corp. (US) | 2022-09-14 | — | — | EP | disclosed |
| EP-4055008-A1 | CANCER TREATMENTS TARGETING CANCER STEM CELLS | Remedy Plan, Inc. (US) | 2022-09-14 | — | — | EP | disclosed |
| US-11440939-B2 | Anticancer peptides | IDP DISCOVERY PHARMA, S.L. (ES) | 2022-09-13 | — | — | US | disclosed |
| CN-111825611-B | 4(1H) -quinovone derivatives and uses thereof | 刘扶东 | 2022-09-09 | — | — | CN | disclosed |
| US-20220281874-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 AND USES THEREOF | Dana-Farber Cancer Institure, Inc. (US) | 2022-09-08 | — | — | US | disclosed |
| US-20220281814-A1 | HDAC6 INHIBITORS AND USES THEREOF | EIKONIZO THERAPEUTICS, INC. (US) | 2022-09-08 | — | — | US | disclosed |
| US-11434229-B2 | 4,9-dioxo-4,9-dihydronaphtho[2,3-b]furan-3-carboxamide derivatives and uses thereof for treating proliferative diseases and infectious diseases | ACADEMIA SINICA (TW) | 2022-09-06 | — | — | US | disclosed |
| US-11433144-B2 | Biodegradable lipids for delivery of nucleic acids | TRANSLATE BIO, INC. (US) | 2022-09-06 | — | — | US | disclosed |
| WO-2022182415-A1 | HIMASTATIN DERIVATIVES, AND PROCESSES OF PREPARATION THEREOF, AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2022-09-01 | — | — | WO | disclosed |
| US-20220275017-A1 | MINIMAL SAPONIN ANALOGUES, SYNTHESIS AND USE THEREOF | MEMORIAL SLOAN-KETTERING CANCER CENTER | 2022-09-01 | — | — | US | disclosed |
| CN-114945572-A | HBF pharmacological inducing compounds for the treatment of sickle cell anemia and beta-thalassemia | 刘扶东 | 2022-08-26 | — | — | CN | disclosed |
| WO-2022178428-A1 | TARGETED BIFUNCTIONAL DEGRADERS AND METHODS USING SAME | YALE UNIVERSITY (US) | 2022-08-25 | — | — | WO | disclosed |
| US-20220267286-A2 | 2-THIOXOTHIAZOLIDIN-4-ONE DERIVATIVES ACTIVE AS TRANSTHYRETIN LIGANDS AND USES THEREOF | BSIM THERAPEUTICS, S.A. (PT) | 2022-08-25 | — | — | US | disclosed |
| US-20220265857-A1 | COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS | MODERNATX, INC. (US) | 2022-08-25 | — | — | US | disclosed |
| EP-4047001-A2 | BICYCLIC UREA KINASE INHIBITORS AND USES THEREOF | The Broad Institute, Inc. (US) | 2022-08-24 | — | — | EP | disclosed |
| EP-4045562-A2 | BRUSH PRODRUGS AND USES THEREOF | Massachusetts Institute of Technology (US) | 2022-08-24 | — | — | EP | disclosed |
| EP-4047002-A1 | ANTITUMORAL COMPOUNDS | Pharma Mar, S.A. (ES) | 2022-08-24 | — | — | EP | disclosed |
| US-11419335-B2 | N-arylated analogues and uses thereof | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2022-08-23 | — | — | US | disclosed |
| WO-2022174184-A1 | PYRROLO[3,2-D]PYRIMIDINE COMPOUNDS AND METHODS OF USE IN THE TREATMENT OF CANCER | TANGO THERAPEUTICS, INC. (US) | 2022-08-18 | — | — | WO | disclosed |
| EP-4041239-A1 | A PYRAZOLOPYRIMIDINE DERIVATIVE AS A HCK INHIBITOR FOR USE IN THERAPY, IN PARTICULAR MYD88 MUTATED DISEASES | Dana-Farber Cancer Institute, Inc. (US) | 2022-08-17 | — | — | EP | disclosed |
| EP-4041401-A1 | HCK AS A THERAPEUTIC TARGET IN MYD88 MUTATED DISEASES | Dana-Farber Cancer Institute, Inc. (US) | 2022-08-17 | — | — | EP | disclosed |
| EP-3291676-B1 | MITRAGYNINE ANALOGS AND USES THEREOF | MEMORIAL SLOAN KETTERING CANCER CENTER (US) | 2022-08-17 | — | — | EP | disclosed |
| EP-4041236-A1 | TRICYCLIC KINASE INHIBITORS AND USES THEREOF | Dana-Farber Cancer Institute, Inc. (US) | 2022-08-17 | — | — | EP | disclosed |
| US-11414393-B2 | Aminoalcohol lipidoids and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2022-08-16 | — | — | US | disclosed |
| WO-2022169985-A1 | HDAC6 INHIBITORS AND USES THEREOF | EIKONIZO THERAPEUTICS, INC. (US) | 2022-08-11 | — | — | WO | disclosed |
| US-20220251288-A1 | REPROCESSABLE COMPOSITIONS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2022-08-11 | — | — | US | disclosed |
| US-20220249539-A1 | BOLAAMPHIPHILIC COMPOUNDS, COMPOSITIONS AND USES THEREOF | LAUREN SCIENCES LLC | 2022-08-11 | — | — | US | disclosed |
| WO-2022168093-A1 | ACTIVE AGENT-RELEASING HYALURONIC ACID VEHICLE | Ariel Scientific Innovations Ltd. (IL) | 2022-08-11 | — | — | WO | disclosed |
| WO-2022170155-A2 | TECHNOLOGIES FOR PREVENTING OR TREATING INFECTIONS | BIOHAVEN THERAPEUTICS LTD. (US) | 2022-08-11 | — | — | WO | disclosed |
| EP-4039698-A1 | PEPTIDES WITH ANTI-CANCER ACTIVITY | IDP Discovery Pharma, S.L. (ES) | 2022-08-10 | — | — | EP | disclosed |
| EP-4037695-A2 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | Wave Life Sciences Ltd. (SG) | 2022-08-10 | — | — | EP | disclosed |
| US-11406645-B2 | Acetamide thienotriazolodiazepines and uses thereof | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2022-08-09 | — | — | US | disclosed |
| US-11407762-B2 | Macrocyclic compounds and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2022-08-09 | — | — | US | disclosed |
| WO-2022164503-A1 | REPROCESSABLE COMPOSITIONS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2022-08-04 | — | — | WO | disclosed |
| US-20220242867-A1 | NOVEL IMIDAZOPYRIMIDINE COMPOUNDS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2022-08-04 | — | — | US | disclosed |
| US-20220242865-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASES | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2022-08-04 | — | — | US | disclosed |
| US-20220242872-A1 | E3 LIGASE BINDERS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2022-08-04 | — | — | US | disclosed |
| US-20220242883-A1 | Antitumoral Compounds | PHARMA MAR SA (ES) | 2022-08-04 | — | — | US | disclosed |
| EP-4036101-A1 | MODIFIED OLIGOMERIC COMPOUNDS COMPRISING TRICYCLO-DNA NUCLEOSIDES AND USES THEREOF | Synthena AG (CH) | 2022-08-03 | — | — | EP | disclosed |
| WO-2022159688-A1 | DEGRADERS OF GRK2 AND USES THEREOF | CYGNAL THERAPEUTICS, INC. (US) | 2022-07-28 | — | — | WO | disclosed |
| US-20220235088-A1 | INHIBITORS OF ADENYLATE-FORMING ENZYME MENE | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2022-07-28 | — | — | US | disclosed |
| US-20220227734-A1 | DEGRADERS OF CYCLIN-DEPENDENT KINASE 12 (CDK12) AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2022-07-21 | — | — | US | disclosed |
| WO-2022155418-A1 | MODIFIED OLIGONUCLEOTIDES | ALNYLAM PHARMACEUTICALS, INC. (US) | 2022-07-21 | — | — | WO | disclosed |
| WO-2022155289-A1 | PEGYLATED P-SELECTIN INHIBITORS | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. (US) | 2022-07-21 | — | — | WO | disclosed |
| EP-4027993-A1 | CYCLOOXYGENASE-2 INHIBITORS AND USES THEREOF | The Broad Institute Inc. (US) | 2022-07-20 | — | — | EP | disclosed |
| EP-4028028-A1 | SYSTEMS AND ASSAYS FOR IDENTIFYING PU.1 INHIBITORS | Massachusetts Institute of Technology (US) | 2022-07-20 | — | — | EP | disclosed |
| EP-4029859-A1 | 2-OXOTHIAZOLIDIN-4-ONE DERIVATIVES ACTIVE AS TRANSTHYRETIN LIGANDS AND USES THEREOF | BSIM THERAPEUTICS, S.A. (PT) | 2022-07-20 | — | — | EP | disclosed |
| EP-4027994-A1 | KDM INHIBITORS AND USES THEREOF | Dana-Farber Cancer Institute, Inc. (US) | 2022-07-20 | — | — | EP | disclosed |
| US-20220218829-A1 | NUCLEIC ACID CONJUGATES AND USES THEREOF | TRANSLATE BIO MA, INC. (US) | 2022-07-14 | — | — | US | disclosed |
| US-20220218730-A1 | COMPOUNDS AND PHARMACEUTICAL USES THEREOF | SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) | 2022-07-14 | — | — | US | disclosed |
| WO-2022150768-A1 | YAP-TEAD INHIBITORS AND USES THEREOF | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2022-07-14 | — | — | WO | disclosed |
| WO-2022150754-A2 | ANTICANCER COMPOUNDS AND USES THEREOF | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2022-07-14 | — | — | WO | disclosed |
| EP-4025253-A1 | DRUG ANTIBODY CONJUGATES | Pharma Mar S.A. (ES) | 2022-07-13 | — | — | EP | disclosed |
| EP-3612546-B1 | MODIFIED OLIGOMERIC COMPOUNDS COMPRISING TRICYCLO-DNA NUCLEOSIDES AND USES THEREOF | SYNTHENA AG (CH) | 2022-07-13 | — | — | EP | disclosed |
| US-11382984-B2 | Conjugates of tumor necrosis factor inhibitors to functionalized polymers | QUIAPEG PHARMACEUTICALS AB (SE) | 2022-07-12 | — | — | US | disclosed |
| US-20220213067-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASE 12 (CDK12) AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2022-07-07 | — | — | US | disclosed |
| US-20220213076-A1 | GHRELIN O-ACYLTRANSFERASE INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2022-07-07 | — | — | US | disclosed |
| WO-2022144401-A1 | VEGF-REGULATING PEPTIDES | IDP DISCOVERY PHARMA, S.L. (ES) | 2022-07-07 | — | — | WO | disclosed |
| EP-3544971-B1 | INHIBITORS OF CYCLIN-DEPENDENT KINASE 12 (CDK12) AND USES THEREOF | DANA FARBER CANCER INST INC (US) | 2022-07-06 | — | — | EP | disclosed |
| EP-4022059-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | Wave Life Sciences Ltd. (SG) | 2022-07-06 | — | — | EP | disclosed |
| EP-4023295-A1 | VEGF-REGULATING PEPTIDES | IDP Discovery Pharma, S.L. (ES) | 2022-07-06 | — | — | EP | disclosed |
| EP-3461525-B1 | A UROLOGICAL DEVICE | COLOPLAST AS (DK) | 2022-07-06 | — | — | EP | disclosed |
| EP-3188799-B1 | METHODS FOR TREATING AGING AND SKIN DISORDERS USING NUCLEIC ACIDS TARGETING TYR OR MMP1 | PHIO PHARM CORP (US) | 2022-07-06 | — | — | EP | disclosed |
| EP-4019515-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASES | Dana-Farber Cancer Institute, Inc. (US) | 2022-06-29 | — | — | EP | disclosed |
| US-11369611-B2 | Therapeutic compounds and uses thereof | KALA PHARMACEUTICALS, INC. (US) | 2022-06-28 | — | — | US | disclosed |
| US-20220195429-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2022-06-23 | — | — | US | disclosed |
| WO-2022133265-A1 | STEROIDAL COMPOUND DERIVATIVES AS THERAPEUTIC AGENTS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORTED (US) | 2022-06-23 | — | — | WO | disclosed |
| EP-3052501-B1 | BICYCLIC ALKYNE DERIVATIVES AND USES THEREOF | AGENCY SCIENCE TECH & RES (SG) | 2022-06-22 | — | — | EP | disclosed |
| EP-2956138-B1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | KALA PHARMACEUTICALS INC (US) | 2022-06-22 | — | — | EP | disclosed |
| US-20220186217-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2022-06-16 | — | — | US | disclosed |
| US-20220175934-A1 | MULTIVALENT LIGAND CLUSTERS FOR TARGETED DELIVERY OF THERAPEUTIC AGENTS | MITOTHERAPEUTIX LLC | 2022-06-09 | — | — | US | disclosed |
| US-20220177508-A1 | C10-Cyclic Substituted 13-Membered Macrolides and Uses Thereof | ZIKANI THERAPEUTICS, INC. | 2022-06-09 | — | — | US | disclosed |
| US-20220177522-A1 | PROLINE-LOCKED STAPLED PEPTIDES AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2022-06-09 | — | — | US | disclosed |
| WO-2022120132-A1 | ANTIBODY-OLIGONUCLEOTIDE COMPLEXES AND USES THEREOF | DYNE THERAPEUTICS, INC. (US) | 2022-06-09 | — | — | WO | disclosed |
| EP-4007563-A1 | MELANOCYTE-REGULATING PEPTIDES | IDP Discovery Pharma, S.L. (ES) | 2022-06-08 | — | — | EP | disclosed |
| EP-2988597-B1 | MACROLIDES AND METHODS OF THEIR PREPARATION AND USE | HARVARD COLLEGE (US) | 2022-06-08 | — | — | EP | disclosed |
| US-11352395-B2 | Anticancer peptides | IDP DISCOVERY PHARMA, S.L. (ES) | 2022-06-07 | — | — | US | disclosed |
| US-11352343-B2 | Urea derivatives and uses thereof | KALA PHARMACEUTICALS, INC. (US) | 2022-06-07 | — | — | US | disclosed |
| US-20220169631-A9 | TAIRE FAMILY KINASE INHIBITORS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2022-06-02 | — | — | US | disclosed |
| EP-3587409-B1 | BIODEGRADABLE LIPIDS FOR DELIVERY OF NUCLEIC ACIDS | TRANSLATE BIO INC (US) | 2022-06-01 | — | — | EP | disclosed |
| EP-4003319-A2 | HDAC6 INHIBITORS AND USES THEREOF | Eikonizo Therapeutics, Inc. (US) | 2022-06-01 | — | — | EP | disclosed |
| EP-4003335-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 AND USES THEREOF | Dana-Farber Cancer Institute, Inc. (US) | 2022-06-01 | — | — | EP | disclosed |
| US-20220162209-A1 | SALICYL-ADENOSINEMONOSULFAMATE ANALOGS AND USES THEREOF | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2022-05-26 | — | — | US | disclosed |
| US-20220160702-A1 | KINASE INHIBITORS AND METHODS OF USE THEREOF | THE BROAD INSTITUTE, INC. (US) | 2022-05-26 | — | — | US | disclosed |
| US-20220162598-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2022-05-26 | — | — | US | disclosed |
| US-20220162333-A1 | GLYCATED CD59 PEPTIDES, THEIR PREPARATION, AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2022-05-26 | — | — | US | disclosed |
| EP-4001290-A1 | TRITERPENE SAPONIN ANALOGUES | Adjuvance Technologies, Inc. (US) | 2022-05-25 | — | — | EP | disclosed |
| US-11338038-B2 | Branched multi-functional macromonomers and related polymers and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2022-05-24 | — | — | US | disclosed |
| US-11339180-B2 | Antitumoral compounds | PHARMA MAR, S.A. (ES) | 2022-05-24 | — | — | US | disclosed |
| US-20220153730-A9 | INHIBITORS OF C-JUN-N-TERMINAL KINASE (JNK) | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2022-05-19 | — | — | US | disclosed |
| US-20220152036-A1 | COMPOUNDS FOR USES IN PHARMACOLOGICAL INDUCTION OF HBF FOR TREATMENT OF SICKLE CELL DISEASE AND ß-THALASSEMIA | ACADEMIA SINICA (TW) | 2022-05-19 | — | — | US | disclosed |
| US-20220152206-A1 | COMPOSITIONS AND METHODS FOR TOPICAL DELIVERY OF PROSTAGLANDINS TO SUBCUTANEOUS FAT | TOPOKINE THERAPEUTICS, INC. | 2022-05-19 | — | — | US | disclosed |
| US-11332480-B2 | Antitumoral compounds | PHARMA MAR, S.A. (ES) | 2022-05-17 | — | — | US | disclosed |
| US-11332496-B2 | Stapled and stitched polypeptides and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2022-05-17 | — | — | US | disclosed |
| US-11331313-B2 | KCC2 expression enhancing compounds and uses thereof | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2022-05-17 | — | — | US | disclosed |
| WO-2022099210-A1 | CROSSLINKING COMONOMERS FOR HIGH PERFORMANCE DEGRADABLE THERMOSETS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2022-05-12 | — | — | WO | disclosed |
| WO-2022099159-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2022-05-12 | — | — | WO | disclosed |
| US-20220145300-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2022-05-12 | — | — | US | disclosed |
| US-20220145295-A1 | ENZYMATIC RNA SYNTHESIS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2022-05-12 | — | — | US | disclosed |
| EP-3993818-A2 | CD38-BINDING AGENTS AND USES THEREOF | Kleo Pharmaceuticals, Inc. (US) | 2022-05-11 | — | — | EP | disclosed |
| US-11325910-B2 | Inhibitors of cyclin-dependent kinases | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2022-05-10 | — | — | US | disclosed |
| US-11324827-B2 | Multifunctionalized polyethylene glycol derivative and preparation method therefor | XIAMEN SINOPEG BIOTECH CO., LTD. (CN) | 2022-05-10 | — | — | US | disclosed |
| US-20220133905-A1 | METHODS FOR ASSEMBLING SCAVENGING PARTICLES | NANOTICS, LLC | 2022-05-05 | — | — | US | disclosed |
| US-20220133736-A1 | USES OF PYRIMIDOPYRIMIDINONES AS SIK INHIBITORS | THE GENERAL HOSPITAL CORPORATION (US) | 2022-05-05 | — | — | US | disclosed |
| US-20220127256-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. | 2022-04-28 | — | — | US | disclosed |
| US-20220127284-A1 | BENZOTHIAZOLE DERIVATIVES AND 7-AZA-BENZOTHIAZOLE DERIVATIVES AS JANUS KINASE 2 INHIBITORS AND USES THEREOF | GRAY NATHANAEL S (US) | 2022-04-28 | — | — | US | disclosed |
| US-20220127260-A1 | IMIDAZOPYRIDINE DERIVATIVES AND AZA-IMIDAZOPYRIDINE DERIVATIVES AS JANUS KINASE 2 INHIBITORS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2022-04-28 | — | — | US | disclosed |
| US-20220127246-A1 | BENZIMIDAZOLE DERIVATIVES AND AZA-BENZIMIDAZOLE DERIVATIVES AS JANUS KINASE 2 INHIBITORS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2022-04-28 | — | — | US | disclosed |
| EP-3986397-A1 | HCK DEGRADERS AND USES THEREOF | Dana-Farber Cancer Institute, Inc. (US) | 2022-04-27 | — | — | EP | disclosed |
| EP-3986914-A1 | CONSTRAINED PEPTIDES | TearSolutions, Inc. (US) | 2022-04-27 | — | — | EP | disclosed |
| US-11312709-B2 | Ghrelin O-acyltransferase inhibitors | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2022-04-26 | — | — | US | disclosed |
| US-11311625-B2 | Peptide-based multiple-drug delivery vehicle | ARIEL-UNIVERSITY RESEARCH AND DEVELOPMENT COMPANY LTD. (IL) | 2022-04-26 | — | — | US | disclosed |
| US-20220118085-A9 | USE OF TOLL-LIKE RECEPTOR 2 (TLR-2) AGONIST FOR MODULATING HUMAN IMMUNE RESPONSE | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2022-04-21 | — | — | US | disclosed |
| US-20220119416-A9 | BIVALENT BROMODOMAIN INHIBITORS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2022-04-21 | — | — | US | disclosed |
| EP-3466942-B1 | PROCESSES FOR THE PREPARATION OF (S)-3-4-((4-(MORPHOLINOMETHYL) BENZYL)OXY)-1-OXOISOINDOLIN-2-YL) PIPERIDINE-2,6-DIONE AND PHARMACEUTICALLY ACCEPTABLE FORMS THEREOF | CELGENE CORP (US) | 2022-04-20 | — | — | EP | disclosed |
| US-11304964-B2 | Bolaamphiphilic compounds, compositions and uses thereof | LAUREN SCIENCES LLC (US) | 2022-04-19 | — | — | US | disclosed |
| US-11306070-B2 | Inhibitors of cyclin-dependent kinase 12 (CDK12) and uses thereof | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2022-04-19 | — | — | US | disclosed |
| US-20220112216-A1 | TRICYCLIC COMPOUNDS AS GLYCOGEN SYNTHASE KINASE 3 (GSK3) INHIBITORS AND USES THEREOF | THE BROAD INSTITUTE, INC. (US) | 2022-04-14 | — | — | US | disclosed |
| WO-2022073920-A1 | OLIGOMERIC COMPOUND FOR DYSTROPHIN RESCUE IN DMD PATIENTS THROUGHOUT SKIPPING OF EXON-51 | SQY THERAPEUTICS (FR) | 2022-04-14 | — | — | WO | disclosed |
| WO-2022076922-A1 | N-ACETYLGALACTOSAMINE(GAlNAc)-DERIVED COMPOUNDS AND OLIGONUCLEOTIDES | ADARX PHARMACEUTICALS, INC. (US) | 2022-04-14 | — | — | WO | disclosed |
| EP-3980404-A1 | COMPOUNDS FOR THE TREATMENT OF KINASE-DEPENDENT DISORDERS | Exelixis, Inc. (US) | 2022-04-13 | — | — | EP | disclosed |
| US-20220106310-A1 | INHIBITORS OF EGFR AND/OR HER2 AND METHODS OF USE | DANA-FARBER CANCER INSTITUTE, INC. | 2022-04-07 | — | — | US | disclosed |
| US-20220105078-A1 | USES OF 4'-DESFERRITHIOCIN ANALOGS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2022-04-07 | — | — | US | disclosed |
| WO-2022066916-A1 | PIPERAZINE-BASED CATIONIC LIPIDS | TRANSLATE BIO, INC. (US) | 2022-03-31 | — | — | WO | disclosed |
| EP-3386484-B1 | COMPOSITIONS AND METHODS FOR DELIVERY OF THERAPEUTIC AGENTS | MODERNATX INC (US) | 2022-03-30 | — | — | EP | disclosed |
| EP-3972982-A1 | BORONIC ESTER PRODRUGS AND USES THEREOF | Massachusetts Institute of Technology (US) | 2022-03-30 | — | — | EP | disclosed |
| US-11285222-B2 | Compositions and methods for delivery of agents | MODERNATX, INC. (US) | 2022-03-29 | — | — | US | disclosed |
| US-11285158-B2 | Uses of pyrimidopyrimidinones as SIK inhibitors | THE GENERAL HOSPITAL CORPORATION (US) | 2022-03-29 | — | — | US | disclosed |
| US-20220089611-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2022-03-24 | — | — | US | disclosed |
| US-20220089632-A1 | NOVEL BICYCLIC NUCLEOSIDES AND OLIGOMERS PREPARED THEREFROM | UNIV BERN (CH) | 2022-03-24 | — | — | US | disclosed |
| EP-3414224-B1 | INHIBITOR OF INDOLEAMINE-2,3-DIOXYGENASE (IDO) | INVENTISBIO LLC (US) | 2022-03-23 | — | — | EP | disclosed |
| US-11279734-B2 | Solution-phase affinity selection of inhibitors from combinatorial peptide libraries | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2022-03-22 | — | — | US | disclosed |
| US-11279934-B2 | Methods for treating cancer using nucleic acids targeting MDM2 or MYCN | PHIO PHARMACEUTICALS CORP. (US) | 2022-03-22 | — | — | US | disclosed |
| US-11274116-B2 | Minimal saponin analogues, synthesis and use thereof | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2022-03-15 | — | — | US | disclosed |
| US-20220073554-A1 | LINCOSAMIDE ANTIBIOTICS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2022-03-10 | — | — | US | disclosed |
| US-20220073512-A1 | PYRAZOLOPYRIDINE INHIBITORS OF C-JUN-N-TERMINAL KINASES AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2022-03-10 | — | — | US | disclosed |
| US-20220072098-A1 | BOLAAMPHIPHILIC COMPOUNDS, COMPOSITIONS AND USES THEREOF | LAUREN SCIENCES LLC | 2022-03-10 | — | — | US | disclosed |
| EP-3094728-B1 | CHIRAL DESIGN | WAVE LIFE SCIENCES LTD (SG) | 2022-03-09 | — | — | EP | disclosed |
| WO-2022046999-A1 | MODULATORS OF MYB-MEDIATED TRANSCRIPTION AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2022-03-03 | — | — | WO | disclosed |
| US-20220061975-A1 | METHOD OF DELIVERING A UROLOGICAL DEVICE INTO A BLADDER NECK OR URETHRA OF A USER | COLOPLAST A/S (DK) | 2022-03-03 | — | — | US | disclosed |
| EP-3958861-A1 | DEGRADERS OF CYCLIN-DEPENDENT KINASE 12 (CDK12) AND USES THEREOF | Dana-Farber Cancer Institute, Inc. (US) | 2022-03-02 | — | — | EP | disclosed |
| US-20220054486-A1 | INHIBITOR OF INDOLEAMINE-2,3-DIOXYGENASE (IDO) | INVENTISBIO LLC (US) | 2022-02-24 | — | — | US | disclosed |
| US-20220054642-A1 | SUPRAMOLECULAR MODIFICATION OF PROTEINS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2022-02-24 | — | — | US | disclosed |
| US-20220055998-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASES | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2022-02-24 | — | — | US | disclosed |
| US-20220055993-A1 | COMPOUNDS FOR TREATING PROLIFERATIVE DISEASES | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2022-02-24 | — | — | US | disclosed |
| US-20220056028-A1 | INHIBITORS OF PLASMA KALLIKREIN AND USES THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2022-02-24 | — | — | US | disclosed |
| EP-3661898-B1 | PROCESS FOR DEOXYFLUORINATION OF PHENOLS | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2022-02-23 | — | — | EP | disclosed |
| US-11253601-B2 | Nucleic acid conjugates and uses thereof | TRANSLATE BIO MA, INC. (US) | 2022-02-22 | — | — | US | disclosed |
| US-20220048942-A1 | DOT1L DEGRADERS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2022-02-17 | — | — | US | disclosed |
| US-20220047518-A1 | PEG LIPIDS AND USES THEREOF | Moderna TX, Inc. (US) | 2022-02-17 | — | — | US | disclosed |
| EP-3481830-B1 | BICYCLIC UREA KINASE INHIBITORS AND USES THEREOF | BROAD INST INC (US) | 2022-02-16 | — | — | EP | disclosed |
| US-11248007-B2 | Inhibitors of MALT1 and uses thereof | CORNELL UNIVERSITY (US) | 2022-02-15 | — | — | US | disclosed |
| US-20220041566-A1 | 2-THIOXOTHIAZOLIDIN-4-ONE DERIVATIVES ACTIVE AS TRANSTHYRETIN LIGANDS AND USES THEREOF | BSIM THERAPEUTICS, S.A. (PT) | 2022-02-10 | — | — | US | disclosed |
| WO-2022032144-A1 | SUBSTRATE ADAPTOR INHIBITORS OF PRMT5 AND USES THEREOF | THE BROAD INSTITUTE, INC. (US) | 2022-02-10 | — | — | WO | disclosed |
| EP-3947382-A1 | COMPOUNDS FOR USES IN PHARMACOLOGICAL INDUCTION OF HBF FOR TREATMENT OF SICKLE CELL DISEASE AND BETA-THALASSEMIA | Academia Sinica (TW) | 2022-02-09 | — | — | EP | disclosed |
| US-11241435-B2 | Uses of salt-inducible kinase (SIK) inhibitors for treating osteoporosis | THE GENERAL HOSPITAL CORPORATION (US) | 2022-02-08 | — | — | US | disclosed |
| US-11242331-B2 | Analogs of yohimbine and uses thereof | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2022-02-08 | — | — | US | disclosed |
| WO-2021234459-A9 | DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO | WAVE LIFE SCIENCES LTD. (SG) | 2022-02-03 | — | — | WO | disclosed |
| WO-2022026892-A1 | PIPERIDIN-1- YL-N-PYRYDI NE-3-YL-2-OXOACET AM IDE DERIVATIVES USEFUL FOR THE TREATMENT OF MTAP-DEFICIENT AND/OR MT A-ACCUMULATING CANCERS | TANGO THERAPEUTICS, INC. (US) | 2022-02-03 | — | — | WO | disclosed |
| US-20220031631-A1 | HIGH-PURITY PEG LIPIDS AND USES THEREOF | MODERNATX, INC. (US) | 2022-02-03 | — | — | US | disclosed |
| US-20220031856-A1 | CONJUGATES OF TUMOR NECROSIS FACTOR INHIBITORS TO FUNCTIONALIZED POLYMERS | FISH & RICHARDSON PC | 2022-02-03 | — | — | US | disclosed |
| US-11236082-B2 | EZH2 inhibitors and uses thereof | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2022-02-01 | — | — | US | disclosed |
| US-20220024923-A1 | MITRAGYNINE ANALOGS AND USES THEREOF | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2022-01-27 | — | — | US | disclosed |
| US-20220024929-A9 | INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 (CDK7) | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2022-01-27 | — | — | US | disclosed |
| EP-3941924-A1 | TECHNOLOGIES USEFUL FOR OLIGONUCLEOTIDE PREPARATION | Wave Life Sciences Ltd. (SG) | 2022-01-26 | — | — | EP | disclosed |
| US-20220017459-A1 | COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS | LANTHEUS MEDICAL IMAGING, INC. (US) | 2022-01-20 | — | — | US | disclosed |
| US-20220017898-A1 | OLIGONUCLEOTIDES CONJUGATES COMPRISING 7'-5'-ALPHA-ANOMERIC-BICYCLIC SUGAR NUCLEOSIDES | ALPHA ANOMERIC SAS (FR) | 2022-01-20 | — | — | US | disclosed |
| US-20220016613-A1 | NOVEL ANNULATION CATALYSTS VIA DIRECT C-H BOND AMINATION | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2022-01-20 | — | — | US | disclosed |
| US-11225469-B2 | Inhibitors of phosphoglycerate dehydrogenase (PHGDH) and uses thereof | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2022-01-18 | — | — | US | disclosed |
| US-11220513-B2 | Chromium-mediated coupling and application to the synthesis of halichondrins | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2022-01-11 | — | — | US | disclosed |
| US-20220002768-A1 | ENZYMATIC SYNTHESIS OF KAVALACTONES AND FLAVOKAVAINS | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2022-01-06 | — | — | US | disclosed |
| US-20220002769-A1 | ENZYMATIC SYNTHESIS OF KAVALACTONES AND FLAVOKAVAINS | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2022-01-06 | — | — | US | disclosed |
| CN-110240605-B | Preparation method of artemisinin dimer | 中国科学院上海药物研究所 | 2021-12-31 | — | — | CN | disclosed |
| EP-3929202-A1 | MINIMAL SAPONIN ANALOGUES, SYNTHESIS AND USE THEREOF | Memorial Sloan-Kettering Cancer Center (US) | 2021-12-29 | — | — | EP | disclosed |
| US-11208390-B2 | Functionalized 1,2,4,5-tetrazine compounds for use in bioorthogonal coupling reactions | THE GENERAL HOSPITAL CORPORATION (US) | 2021-12-28 | — | — | US | disclosed |
| US-11207379-B2 | Peptides with anti-cancer activity | IDP DISCOVERY PHARMA, S.L. (ES) | 2021-12-28 | — | — | US | disclosed |
| US-20210393647-A9 | ACETAMIDE THIENOTRIAZOLODIAZEPINES AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2021-12-23 | — | — | US | disclosed |
| US-20210393641-A1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | OXFORD FINANCE LLC | 2021-12-23 | — | — | US | disclosed |
| US-20210393648-A1 | METHODS AND COMPOSITIONS FOR REDUCING BODY FAT AND ADIPOCYTES | TOPOKINE THERAPEUTICS, INC. | 2021-12-23 | — | — | US | disclosed |
| EP-3923989-A1 | MULTIVALENT LIGAND CLUSTERS FOR TARGETED DELIVERY OF THERAPEUTIC AGENTS | Mitotherapeutix LLC (US) | 2021-12-22 | — | — | EP | disclosed |
| US-11203601-B2 | Tricyclic compounds as glycogen synthase kinase 3 (GSK3) inhibitors and uses thereof | THE BROAD INSTITUTE, INC. (US) | 2021-12-21 | — | — | US | disclosed |
| US-11202697-B2 | Kit of parts including a urological device | COLOPLAST A/S (DK) | 2021-12-21 | — | — | US | disclosed |
| US-20210386861-A1 | BRUSH PRODRUGS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2021-12-16 | — | — | US | disclosed |
| US-20210388196-A1 | GENE DELIVERY CARRIER | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2021-12-16 | — | — | US | disclosed |
| EP-3921324-A1 | INHIBITORS OF ADENYLATE-FORMING ENZYME MENE | Memorial Sloan Kettering Cancer Center (US) | 2021-12-15 | — | — | EP | disclosed |
| US-11197857-B2 | Combination therapy | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2021-12-14 | — | — | US | disclosed |
| US-20210380588-A1 | Novel Compounds and Uses Thereof | OXFORD FINANCE LLC | 2021-12-09 | — | — | US | disclosed |
| US-11192866-B2 | Synthesis of tetracyclines and analogues thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2021-12-07 | — | — | US | disclosed |
| US-11191841-B2 | Supramolecular modification of proteins | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2021-12-07 | — | — | US | disclosed |
| US-20210369866-A1 | BIODEGRADABLE LIPIDS FOR DELIVERY OF NUCLEIC ACIDS | TRANSLATE BIO, INC. | 2021-12-02 | — | — | US | disclosed |
| US-11185531-B2 | Arginine methyltransferase inhibitors and uses thereof | Epizyme, Inc. (US) | 2021-11-30 | — | — | US | disclosed |
| US-11185853-B2 | Catalysts for polycarbonate production | SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) | 2021-11-30 | — | — | US | disclosed |
| US-11186574-B2 | Inhibitors of EGFR and/or HER2 and methods of use | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2021-11-30 | — | — | US | disclosed |
| WO-2021237223-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2021-11-25 | — | — | WO | disclosed |
| WO-2021236911-A1 | LINCOSAMIDE ANTIBIOTICS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2021-11-25 | — | — | WO | disclosed |
| WO-2021234459-A2 | DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO | WAVE LIFE SCIENCES LTD. (SG) | 2021-11-25 | — | — | WO | disclosed |
| US-11179708-B2 | Compositions and methods for selective carbonylation of heterocyclic compounds | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2021-11-23 | — | — | US | disclosed |
| US-11179710-B2 | Direct palladium-catalyzed aromatic fluorination | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2021-11-23 | — | — | US | disclosed |
| US-11180492-B2 | Anti-parasitic compounds and uses thereof | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) | 2021-11-23 | — | — | US | disclosed |
| US-20210353607-A1 | PI3K INHIBITORS AND USES THEREOF | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2021-11-18 | — | — | US | disclosed |
| US-20210355119-A1 | CYANO QUINOLINE AMIDE COMPOUNDS AS HER2 INHIBITORS AND METHODS OF USE | DANA-FARBER CANCER INSTITUTE, INC. | 2021-11-18 | — | — | US | disclosed |
| EP-3544970-B1 | INHIBITORS OF INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASES AND USES THEREOF | DANA FARBER CANCER INST INC (US) | 2021-11-17 | — | — | EP | disclosed |
| EP-3560503-B1 | RNA INTERFERENCE IN DERMAL AND FIBROTIC INDICATIONS | PHIO PHARM CORP (US) | 2021-11-17 | — | — | EP | disclosed |
| EP-2331018-B1 | Intraluminal device | COLOPLAST AS (DK) | 2021-11-17 | — | — | EP | disclosed |
| EP-3908583-A1 | DOT1L DEGRADERS AND USES THEREOF | Dana-Farber Cancer Institute, Inc. (US) | 2021-11-17 | — | — | EP | disclosed |
| US-11174223-B2 | Compositions, methods, and systems for the synthesis and use of imaging agents | LANTHEUS MEDICAL IMAGING, INC. (US) | 2021-11-16 | — | — | US | disclosed |
| US-20210348169-A1 | METHODS FOR TREATING AGING AND SKIN DISORDERS USING NUCLEIC ACIDS TARGETING TYR OR MMP1 | PHIO PHARMACEUTICALS CORP. (US) | 2021-11-11 | — | — | US | disclosed |
| US-20210346367-A1 | O-GLCNAC TRANSFERASE INHIBITORS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2021-11-11 | — | — | US | disclosed |
| US-11168083-B2 | Inhibitors of Plasma Kallikrein and uses thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2021-11-09 | — | — | US | disclosed |
| WO-2021222542-A1 | 5-AMINO-2-PIPERIDINON-3-YL-1-OXOISOINDOLINE DERIVATIVES FOR DEGRADATION OF IKZF2 DEGRADERS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2021-11-04 | — | — | WO | disclosed |
| US-20210340094-A1 | CO-CRYSTALS OF SODIUM BENZOATE AND USES THEREOF | SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) | 2021-11-04 | — | — | US | disclosed |
| EP-3902542-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 AND USES THEREOF | Dana-Farber Cancer Institute, Inc. (US) | 2021-11-03 | — | — | EP | disclosed |
| US-11161910-B2 | Glycated CD59 peptides, their preparation, and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2021-11-02 | — | — | US | disclosed |
| US-20210329919-A9 | SYNTHESIS AND ANTI-CANCER ACTIVITY OF COMMUNESIN ALKALOIDS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2021-10-28 | — | — | US | disclosed |
| US-20210332048-A1 | MEROPENEM DERIVATIVES AND USES THEREOF | KALA PHARMACEUTICALS, INC. | 2021-10-28 | — | — | US | disclosed |
| WO-2021214126-A1 | DRUG ANTIBODY CONJUGATES | PHARMA MAR, S.A. (ES) | 2021-10-28 | — | — | WO | disclosed |
| WO-2021216828-A1 | CHIMERIC DEGRADERS OF CYCLIN-DEPENDENT KINASE 9 AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2021-10-28 | — | — | WO | disclosed |
| EP-3897667-A2 | SALICYL-ADENOSINEMONOSULFAMATE ANALOGS AND USES THEREOF | Memorial Sloan Kettering Cancer Center (US) | 2021-10-27 | — | — | EP | disclosed |
| US-11155562-B2 | Synthesis of halichondrin analogs and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2021-10-26 | — | — | US | disclosed |
| US-11155674-B2 | Polymerizable sulfonamide compounds and polymers thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2021-10-26 | — | — | US | disclosed |
| EP-3893879-A1 | PYRAZOLOPYRIDINE INHIBITORS OF C-JUN-N-TERMINAL KINASES AND USES THEREOF | Dana-Farber Cancer Institute, Inc. (US) | 2021-10-20 | — | — | EP | disclosed |
| EP-3430031-B1 | PEPTIDES WITH ANTI-CANCER ACTIVITY | IDP DISCOVERY PHARMA S L (ES) | 2021-10-20 | — | — | EP | disclosed |
| US-20210317143-A9 | BORONIC ESTER PRODRUGS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2021-10-14 | — | — | US | disclosed |
| US-20210315894-A9 | 4,6-PYRIMIDINYLENE DERIVATIVES AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2021-10-14 | — | — | US | disclosed |
| US-20210317105-A9 | INHIBITORS OF CYCLIN-DEPENDENT KINASE 12 (CDK12) AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2021-10-14 | — | — | US | disclosed |
| US-11142507-B2 | Inhibitors of cyclin-dependent kinases | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2021-10-12 | — | — | US | disclosed |
| WO-2021203055-A1 | VIRAL ENTRY INHIBITORS AND RNA POLYMERASE INHIBITORS | SELVA THERAPEUTICS, INC. (US) | 2021-10-07 | — | — | WO | disclosed |
| US-20210308121-A1 | PRMT5 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2021-10-07 | — | — | US | disclosed |
| WO-2021202694-A1 | PHENOLIC ACID LIPID BASED CATIONIC LIPIDS | TRANSLATE BIO, INC. (US) | 2021-10-07 | — | — | WO | disclosed |
| EP-3889139-A1 | COMPOUNDS FOR TREATING PROLIFERATIVE DISEASES | The Children's Medical Center Corporation (US) | 2021-10-06 | — | — | EP | disclosed |
| US-11136291-B2 | Antifungal compounds and uses thereof | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2021-10-05 | — | — | US | disclosed |
| WO-2021127375-A9 | HYALURONIC ACID DERIVATIVES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2021-09-30 | — | — | WO | disclosed |
| WO-2021195024-A1 | ADJUVANT COMPOUNDS, SALT FORMS, AND FORMULATIONS | ADJUVANCE TECHNOLOGIES, INC. (US) | 2021-09-30 | — | — | WO | disclosed |
| US-20210300911-A1 | INHIBITORS OF C-JUN-N-TERMINAL KINASE (JNK) | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2021-09-30 | — | — | US | disclosed |
| US-20210299237-A1 | TRITERPENE SAPONIN SYNTHESIS, INTERMEDIATES AND ADJUVANT COMBINATIONS | ADJUVANCE TECHNOLOGIES, INC. (US) | 2021-09-30 | — | — | US | disclosed |
| WO-2021195401-A1 | TECHNOLOGIES FOR PREVENTING OR TREATING INFECTIONS | BIOHAVEN THERAPEUTICS LTD. (US) | 2021-09-30 | — | — | WO | disclosed |
| EP-3885343-A1 | INDOLE COMPOUNDS AS EZH2 INHIBITORS AND USES THEREOF | Dana-Farber Cancer Institute, Inc. (US) | 2021-09-29 | — | — | EP | disclosed |
| EP-3883647-A1 | C10-ALKYLENE SUBSTITUTED 13-MEMBERED MACROLIDES AND USES THEREOF | Zikani Therapeutics, Inc. (US) | 2021-09-29 | — | — | EP | disclosed |
| EP-3883945-A1 | C11-CYCLIC SUBSTITUTED 13-MEMBERED MACROLIDES AND USES THEREOF | Zikani Therapeutics, Inc. (US) | 2021-09-29 | — | — | EP | disclosed |
| US-11130764-B2 | Analogs of vincamine and uses thereof | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2021-09-28 | — | — | US | disclosed |
| US-20210292299-A1 | TAIRE FAMILY KINASE INHIBITORS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2021-09-23 | — | — | US | disclosed |
| WO-2021188659-A1 | HELICAL STAPLED PEPTIDES AND USES THEREOF | FOG PHARMACEUTICALS, INC. (US) | 2021-09-23 | — | — | WO | disclosed |
| WO-2021188880-A1 | BENZENESULFONAMIDE DERIVATIVES AS TRAP1 MODULATORS AND USES THEREOF | AMATHUS THERAPEUTICS, INC. (US) | 2021-09-23 | — | — | WO | disclosed |
| WO-2021188907-A1 | PYRIDINESULFONAMIDE DERIVATIVES AS TRAP1 MODULATORS AND USES THEREOF | AMATHUS THERAPEUTICS, INC. (US) | 2021-09-23 | — | — | WO | disclosed |
| WO-2021188911-A1 | CYCLIC SULFONAMIDE DERIVATIVES AS TRAP1 MODULATORS AND USES THEREOF | AMATHUS THERAPEUTICS, INC. (US) | 2021-09-23 | — | — | WO | disclosed |
| EP-3172213-B1 | MACROCYCLIC KINASE INHIBITORS AND USES THEREOF | DANA FARBER CANCER INST INC (US) | 2021-09-22 | — | — | EP | disclosed |
| US-11124534-B2 | Lincosamide antibiotics and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2021-09-21 | — | — | US | disclosed |
| US-20210284664-A1 | DEGRADABLE POLYMERS OF A CYCLIC SILYL ETHER AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2021-09-16 | — | — | US | disclosed |
| US-20210283266-A1 | CONJUGATES OF BIOLOGICALLY ACTIVE MOLECULES TO FUNCTIONALIZED POLYMERS | QUIAPEG PHARMACEUTICALS AB (SE) | 2021-09-16 | — | — | US | disclosed |
| US-20210283248-A1 | TRITERPENE SAPONIN ANALOGUES | ADJUVANCE TECHNOLOGIES, INC. (US) | 2021-09-16 | — | — | US | disclosed |
| EP-3876930-A1 | BENZIMIDAZOLE DERIVATIVES AND AZA-BENZIMIDAZOLE DERIVATIVES AS JANUS KINASE 2 INHIBITORS AND USES THEREOF | Dana-Farber Cancer Institute, Inc. (US) | 2021-09-15 | — | — | EP | disclosed |
| EP-3877371-A1 | IMIDAZOPYRIDINE DERIVATIVES AND AZA-IMIDAZOPYRIDINE DERIVATIVES AS JANUS KINASE 2 INHIBITORS AND USES THEREOF | Dana-Farber Cancer Institute, Inc. (US) | 2021-09-15 | — | — | EP | disclosed |
| EP-3876939-A1 | BENZOTHIAZOLE DERIVATIVES AND 7-AZA-BENZOTHIAZOLE DERIVATIVES AS JANUS KINASE 2 INHIBITORS AND USES THEREOF | Dana-Farber Cancer Institute, Inc. (US) | 2021-09-15 | — | — | EP | disclosed |
| US-11118178-B2 | Reduced size self-delivering RNAI compounds | PHIO PHARMACEUTICALS CORP. (US) | 2021-09-14 | — | — | US | disclosed |
| US-11117877-B2 | 2-thioxothiazolidin-4-one derivatives active as transthyretin ligands and uses thereof | BSIM THERAPEUTICS, S.A. (PT) | 2021-09-14 | — | — | US | disclosed |
| EP-3578183-B1 | RNA INTERFERENCE IN OCULAR INDICATIONS | PHIO PHARM CORP (US) | 2021-09-08 | — | — | EP | disclosed |
| US-20210253569-A1 | HETEROARYL COMPOUNDS AND USES THEREOF | APRINOIA THERAPEUTICS INC. (CN) | 2021-08-19 | — | — | US | disclosed |
| US-20210254062-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2021-08-19 | — | — | US | disclosed |
| US-20210253592-A1 | SELECTIVE ESTROGEN RECEPTOR DEGRADERS AND USES THEREOF | INVENTISBIO LLC (US) | 2021-08-19 | — | — | US | disclosed |
| EP-3865135-A2 | NEUROACTIVE STEROIDS FOR USE IN THERAPY | Sage Therapeutics, Inc. (US) | 2021-08-18 | — | — | EP | disclosed |
| EP-3864151-A2 | ENZYMATIC RNA SYNTHESIS | President and Fellows of Harvard College (US) | 2021-08-18 | — | — | EP | disclosed |
| US-11091487-B2 | Meropenem derivatives and uses thereof | KALA PHARMACEUTICALS, INC. (US) | 2021-08-17 | — | — | US | disclosed |
| US-20210246100-A1 | ANTI-FIBROTIC COMPOUNDS | CERTA THERAPEUTICS PTY LTD (AU) | 2021-08-12 | — | — | US | disclosed |
| US-20210246146-A1 | ANTITUMORAL COMPOUNDS | PHARMA MAR SA (ES) | 2021-08-12 | — | — | US | disclosed |
| EP-3862005-A1 | NUCLEIC ACID MOLECULES TARGETING SUPEROXIDE DISMUTASE 1 (SOD1) | Phio Pharmaceuticals Corp. (US) | 2021-08-11 | — | — | EP | disclosed |
| EP-3860597-A1 | PI3K INHIBITORS AND USES THEREOF | Sloan-Kettering Institute for Cancer Research (US) | 2021-08-11 | — | — | EP | disclosed |
| US-11084803-B2 | Activators of class I histone deacetylases (HDACs) and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2021-08-10 | — | — | US | disclosed |
| US-20210236632-A1 | USE OF TOLL-LIKE RECEPTOR 2 (TLR-2) AGONIST FOR MODULATING HUMAN IMMUNE RESPONSE | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2021-08-05 | — | — | US | disclosed |
| US-11077101-B1 | Compounds and methods of use | TANGO THERAPEUTICS, INC. (US) | 2021-08-03 | — | — | US | disclosed |
| US-11078467-B2 | Highly active self-sufficient nitration biocatalysts | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2021-08-03 | — | — | US | disclosed |
| US-20210230226-A1 | ANTICANCER PEPTIDES | IDP DISCOVERY PHARMA, S.L. (ES) | 2021-07-29 | — | — | US | disclosed |
| US-20210230538-A1 | USES OF KINASE INHIBITORS FOR INDUCING AND MAINTAINING PLURIPOTENCY | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2021-07-29 | — | — | US | disclosed |
| US-20210230101-A1 | COMPOUNDS FOR TREATING DENGUE VIRUS INFECTIONS AND OTHER INFECTIONS | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2021-07-29 | — | — | US | disclosed |
| US-20210230177-A1 | SYNTHESIS OF HALICHONDRINS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2021-07-29 | — | — | US | disclosed |
| EP-3853305-A1 | HIGH-PURITY PEG LIPIDS AND USES THEREOF | ModernaTX, Inc. (US) | 2021-07-28 | — | — | EP | disclosed |
| EP-3852732-A1 | PEG LIPIDS AND USES THEREOF | ModernaTX, Inc. (US) | 2021-07-28 | — | — | EP | disclosed |
| WO-2021146553-A1 | MACROMOLECULAR PRODRUGS FOR LIGHT-EMITTING DIODES AND USES THEREOF | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2021-07-22 | — | — | WO | disclosed |
| US-20210221937-A1 | POLYMERS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2021-07-22 | — | — | US | disclosed |
| US-20210221826-A1 | BIVALENT BROMODOMAIN INHIBITORS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2021-07-22 | — | — | US | disclosed |
| US-20210220391-A1 | PROTEOLYSIS TARGETING CHIMERIC MOLECULES (PROTACS) WITH FUNCTIONAL HANDLES AND USES THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2021-07-22 | — | — | US | disclosed |
| EP-3334713-B1 | PHENYLSULFONAMIDO-BENZOFURAN DERIVATIVES AND USES THEREOF IN THE TREATMENT OF PROLIFERATIVE DISEASES | MEMORIAL SLOAN KETTERING CANCER CENTER (US) | 2021-07-21 | — | — | EP | disclosed |
| EP-3149015-B1 | MINIMAL SAPONIN ANALOGUES, SYNTHESIS AND USE THEREOF | MEMORIAL SLOAN KETTERING CANCER CENTER (US) | 2021-07-21 | — | — | EP | disclosed |
| US-11065345-B2 | Methods for assembling scavenging particles | NANOTICS, LLC (US) | 2021-07-20 | — | — | US | disclosed |
| US-20210214385-A1 | INHIBITORS OF D-AMINO ACID OXIDASE AND USES THEREOF | SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) | 2021-07-15 | — | — | US | disclosed |
| US-20210213032-A1 | METHODS AND COMPOSITIONS FOR TOPICAL DELIVERY OF PROSTAGLANDINS TO SUBCUTANEOUS FAT | TOPOKINE THERAPEUTICS, INC. (US) | 2021-07-15 | — | — | US | disclosed |
| US-20210206779-A9 | CYANO THIENOTRIAZOLODIAZEPINES AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2021-07-08 | — | — | US | disclosed |
| US-20210206918-A1 | FUNCTIONALIZED POLYMERS | FISH & RICHARDSON PC | 2021-07-08 | — | — | US | disclosed |
| EP-3844154-A1 | IONIZABLE LIPIDOIDS AND THEIR USES | Massachusetts Institute of Technology (US) | 2021-07-07 | — | — | EP | disclosed |
| US-11053205-B2 | Phenazine derivatives as antimicrobial agents | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2021-07-06 | — | — | US | disclosed |
| US-11052080-B2 | Kinase inhibitors and methods of use thereof | THE BROAD INSTITUTE, INC. (US) | 2021-07-06 | — | — | US | disclosed |
| WO-2021133896-A1 | TRANSCRIPTIONAL ENHANCED ASSOCIATE DOMAN (TEAD) TRANSCRIPTION FACTOR INHIBITORS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2021-07-01 | — | — | WO | disclosed |
| WO-2021133601-A1 | THE COMBINATION OF CYCLIN DEPENDENT KINASE 7 INHIBITOR AND IMMUNOTHERAPY FOR TREATMENT OF CANCER | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2021-07-01 | — | — | WO | disclosed |
| EP-2892511-B1 | BOLAAMPHIPHILIC COMPOUNDS, COMPOSITIONS AND USES THEREOF | LAUREN SCIENCES LLC (US) | 2021-06-30 | — | — | EP | disclosed |
| US-11046692-B2 | Mitragynine analogs and uses thereof | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2021-06-29 | — | — | US | disclosed |
| US-11046628-B2 | Process for deoxyfluorination of phenols | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2021-06-29 | — | — | US | disclosed |
| US-20210188787-A1 | DOTA COMPOUNDS AND USES THEREOF | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2021-06-24 | — | — | US | disclosed |
| US-20210189018-A1 | HYALURONIC ACID DERIVATIVES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2021-06-24 | — | — | US | disclosed |
| WO-2021127375-A1 | HYALURONIC ACID DERIVATIVES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2021-06-24 | — | — | WO | disclosed |
| EP-3837266-A1 | DEGRADABLE POLYMERS OF A CYCLIC SILYL ETHER AND USES THEREOF | Massachusetts Institute of Technology (US) | 2021-06-23 | — | — | EP | disclosed |
| US-11040978-B2 | Bicyclic heterocyclic derivatives as MNK1 and MNK2 modulators and uses thereof | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2021-06-22 | — | — | US | disclosed |
| US-11041069-B2 | Gene delivery carrier | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2021-06-22 | — | — | US | disclosed |
| US-11040976-B2 | Substrate selective inhibitors of insulin-degrading enzyme (IDE) and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2021-06-22 | — | — | US | disclosed |
| US-11040106-B2 | Conjugates of kinase inhibitors and cyanine dyes | Small Molecule PPI Mimics LLC (US) | 2021-06-22 | — | — | US | disclosed |
| US-20210179522-A9 | FE/CU-MEDIATED KETONE SYNTHESIS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2021-06-17 | — | — | US | disclosed |
| US-20210177781-A9 | COMBINATION OF A SELECTIVE HISTONE DEACETYLASE 3 (HDAC3) INHIBITOR AND AN IMMUNOTHERAPY AGENT FOR THE TREATMENT OF CANCER | KDAc Therapeutics, Inc. | 2021-06-17 | — | — | US | disclosed |
| WO-2021118727-A2 | FLUOROGENIC AMINO ACIDS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2021-06-17 | — | — | WO | disclosed |
| WO-2021119249-A1 | CYCLOPHILIN D INHIBITORS AND USES THEREOF | THE BROAD INSTITUTE, INC. (US) | 2021-06-17 | — | — | WO | disclosed |
| EP-3833347-A1 | HISTONE DEMETHYLASE 5 INHIBITORS AND USES THEREOF | Dana-Farber Cancer Institute, Inc. (US) | 2021-06-16 | — | — | EP | disclosed |
| US-11034788-B2 | Polymers and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2021-06-15 | — | — | US | disclosed |
| US-20210171708-A1 | POLYCARBONATE POLYOL COMPOSITIONS AND METHODS | SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) | 2021-06-10 | — | — | US | disclosed |
| US-11028117-B2 | Bicyclic nucleosides and oligomers prepared therefrom | Universität Bern (CH) | 2021-06-08 | — | — | US | disclosed |
| US-11028055-B2 | Compounds for treating proliferative diseases | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2021-06-08 | — | — | US | disclosed |
| US-20210163568-A1 | AZIDE INSULIN ANALOGUES | MERCK SHARP & DOHME CORP. (US) | 2021-06-03 | — | — | US | disclosed |
| US-20210162048-A1 | Photoswitchable HDAC Inhibitors | THE GENERAL HOSPITAL CORPORATION | 2021-06-03 | — | — | US | disclosed |
| US-11021707-B2 | Reduced size self-delivering nucleic acid compounds targeting long non-coding RNA | PHIO PHARMACEUTICALS CORP. (US) | 2021-06-01 | — | — | US | disclosed |
| WO-2021102052-A1 | DIRECTED CONJUGATION TECHNOLOGIES | KLEO PHARMACEUTICALS, INC. (US) | 2021-05-27 | — | — | WO | disclosed |
| US-20210154184-A1 | COMPOUNDS FOR TAU PROTEIN DEGRADATION | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2021-05-27 | — | — | US | disclosed |
| US-20210155631-A1 | CARM1 INHIBITORS AND USES THEREOF | EPIZYME INC (US) | 2021-05-27 | — | — | US | disclosed |
| US-11013757-B2 | Oligonucleotides, compositions and methods thereof | WAVE LIFE SCIENCES LTD. (SG) | 2021-05-25 | — | — | US | disclosed |
| US-11014873-B2 | Anti-fibrotic compounds | CERTA THERAPEUTICS PTY LTD. (AU) | 2021-05-25 | — | — | US | disclosed |
| US-11014876-B2 | Polyamine sulfonamides and uses thereof | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2021-05-25 | — | — | US | disclosed |
| US-11014936-B2 | Selective estrogen receptor degraders and uses thereof | INVENTISBIO LLC (US) | 2021-05-25 | — | — | US | disclosed |
| US-20210147425-A1 | BICYCLIC UREA KINASE INHIBITORS AND USES THEREOF | THE BROAD INSTITUTE, INC. (US) | 2021-05-20 | — | — | US | disclosed |
| US-20210147598-A1 | FUNCTIONAL OLIGOMERS AND FUNCTIONAL POLYMERS INCLUDING HYDROXYLATED POLYMERS AND CONJUGATES THEREOF AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2021-05-20 | — | — | US | disclosed |
| WO-2021096591-A1 | FUNCTIONAL OLIGOMERS AND FUNCTIONAL POLYMERS INCLUDING HYDROXYLATED POLYMERS AND CONJUGATES THEREOF AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2021-05-20 | — | — | WO | disclosed |
| US-20210147351-A9 | ANTIFUNGAL COMPOUNDS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2021-05-20 | — | — | US | disclosed |
| US-20210147470-A1 | NEUROACTIVE STEROIDS, COMPOSITIONS, AND USES THEREOF | SAGE THERAPEUTICS, INC. | 2021-05-20 | — | — | US | disclosed |
| US-20210147388-A1 | IMIDAZOLYL KINASE INHIBITORS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2021-05-20 | — | — | US | disclosed |
| US-20210147390-A1 | ARYL HYDROCARBON RECEPTOR MODULATORS AND USES THEREOF | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. (US) | 2021-05-20 | — | — | US | disclosed |
| EP-3820943-A1 | BICONJUGATABLE LABELS AND METHODS OF USE | Quantum-si Incorporated (US) | 2021-05-19 | — | — | EP | disclosed |
| US-11008290-B2 | Halogenated quinoline derivatives as antimicrobial agents | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2021-05-18 | — | — | US | disclosed |
| US-11008358-B2 | Synthesis of desosamines | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2021-05-18 | — | — | US | disclosed |
| US-11008277-B2 | Co-crystals of sodium benzoate and uses thereof | SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) | 2021-05-18 | — | — | US | disclosed |
| US-11001845-B2 | Nucleic acid molecules targeting superoxide dismutase 1 (SOD1) | PHIO PHARMACEUTICALS CORP. (US) | 2021-05-11 | — | — | US | disclosed |
| US-20210130386-A1 | DOT1L DEGRADERS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2021-05-06 | — | — | US | disclosed |
| US-20210130324-A1 | SMALL MOLECULES THAT BLOCK PROTEASOME-ASSOCIATED UBIQUITIN RECEPTOR RPN13 FUNCTION AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2021-05-06 | — | — | US | disclosed |
| US-20210130821-A1 | CHIRAL CONTROL | WAVE LIFE SCIENCES LTD. (SG) | 2021-05-06 | — | — | US | disclosed |
| WO-2021086879-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2021-05-06 | — | — | WO | disclosed |
| EP-3052134-B1 | GLUCOSE-RESPONSIVE INSULIN CONJUGATES | MERCK SHARP & DOHME (US) | 2021-05-05 | — | — | EP | disclosed |
| EP-3057956-B1 | POLYCYCLIC INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 (CDK7) | DANA FARBER CANCER INST INC (US) | 2021-05-05 | — | — | EP | disclosed |
| EP-3814365-A1 | DOT1L DEGRADER AND USES THEREOF | Dana-Farber Cancer Institute, Inc. (US) | 2021-05-05 | — | — | EP | disclosed |
| EP-3813948-A1 | SUBSTITUTED ALKYLPHENOLS AS HCN1 ANTAGONISTS | Cornell University (US) | 2021-05-05 | — | — | EP | disclosed |
| EP-3810132-A1 | TAIRE FAMILY KINASE INHIBITORS AND USES THEREOF | Dana-Farber Cancer Institute, Inc. (US) | 2021-04-28 | — | — | EP | disclosed |
| US-10988491-B2 | Degradable polymers of a cyclic silyl ether and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2021-04-27 | — | — | US | disclosed |
| US-20210115051-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 (CDK7) | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2021-04-22 | — | — | US | disclosed |
| US-20210113701-A1 | BRUSH PRODRUGS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2021-04-22 | — | — | US | disclosed |
| US-20210115444-A1 | CHIRAL DESIGN | WAVE LIFE SCIENCES LTD. (SG) | 2021-04-22 | — | — | US | disclosed |
| WO-2021076821-A2 | BRUSH PRODRUGS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2021-04-22 | — | — | WO | disclosed |
| US-20210113483-A1 | Cationic Polymers | TRANSLATE BIO, INC. | 2021-04-22 | — | — | US | disclosed |
| EP-3807253-A1 | CYANO QUINOLINE AMIDE COMPOUNDS AS HER2 INHIBITORS AND METHODS OF USE | Dana Farber Cancer Institute, Inc. (US) | 2021-04-21 | — | — | EP | disclosed |
| EP-3806844-A1 | DOTA COMPOUNDS AND USES THEREOF | Memorial Sloan Kettering Cancer Center (US) | 2021-04-21 | — | — | EP | disclosed |
| US-10980807-B2 | Inhibitor of indoleamine-2,3-dioxygenase (IDO) | INVENTISBIO LLC (US) | 2021-04-20 | — | — | US | disclosed |
| US-10981903-B2 | Inhibitors of c-Jun-N-terminal kinase (JNK) | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2021-04-20 | — | — | US | disclosed |
| US-10980794-B2 | PRMT5 inhibitors and uses thereof | Epizyme, Inc. (US) | 2021-04-20 | — | — | US | disclosed |
| US-20210106580-A1 | COMBINATION THERAPY | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2021-04-15 | — | — | US | disclosed |
| US-20210107856-A1 | CO-CRYSTALS OF LITHIUM BENZOATE AND USES THEREOF | SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) | 2021-04-15 | — | — | US | disclosed |
| WO-2021071858-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2021-04-15 | — | — | WO | disclosed |
| US-20210106687-A1 | BOLAAMPHIPHILIC COMPOUNDS, COMPOSITIONS AND USES THEREOF | LAUREN SCIENCES LLC | 2021-04-15 | — | — | US | disclosed |
| WO-2021071922-A1 | A PYRAZOLOPYRIMIDINE DERIVATIVE AS A HCK INHIBITOR FOR USE IN THERAPY, IN PARTICULAR MYD88 MUTATED DISEASES | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2021-04-15 | — | — | WO | disclosed |
| WO-2021071919-A1 | HCK AS A THERAPEUTIC TARGET IN MYD88 MUTATED DISEASES | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2021-04-15 | — | — | WO | disclosed |
| WO-2021071788-A2 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2021-04-15 | — | — | WO | disclosed |
| EP-3801530-A1 | COMBINATION OF A TYPE II PROTEIN ARGININE METHYLTRANSFERASE INHIBITOR AND AN ICOS BINDING PROTEIN TO TREAT CANCER | GlaxoSmithKline Intellectual Property Development Ltd (GB) | 2021-04-14 | — | — | EP | disclosed |
| EP-3801615-A1 | COMBINED THERAPY WITH ICOS BINDING PROTEINS AND ARGININEMETHYLTRANSFERASE INHIBITORS | GlaxoSmithKline Intellectual Property Development Ltd (GB) | 2021-04-14 | — | — | EP | disclosed |
| US-10975051-B2 | Phenylsulfonamido-benzofuran derivatives and uses thereof in the treatment of proliferative diseases | MEMORIAL SLOAN KETTERING CANCER CENTER (US) | 2021-04-13 | — | — | US | disclosed |
| US-10973921-B2 | Conjugates of tumor necrosis factor inhibitors to functionalized polymers | QUIAPEG PHARMACEUTICALS AB (SE) | 2021-04-13 | — | — | US | disclosed |
| US-10975058-B2 | Imidazolyl kinase inhibitors and uses thereof | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2021-04-13 | — | — | US | disclosed |
| US-10973847-B2 | Core-to-surface polymerization for the synthesis of star polymers and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2021-04-13 | — | — | US | disclosed |
| US-10975055-B2 | Inhibitors of interleukin-1 receptor-associated kinases and uses thereof | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2021-04-13 | — | — | US | disclosed |
| US-20210101875-A1 | AMINOALCOHOL LIPIDOIDS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2021-04-08 | — | — | US | disclosed |
| WO-2021067682-A1 | TRICYCLIC KINASE INHIBITORS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2021-04-08 | — | — | WO | disclosed |
| US-10966987-B2 | Therapeutic compounds and uses thereof | KALA PHARMACEUTICALS, INC. (US) | 2021-04-06 | — | — | US | disclosed |
| US-20210093644-A1 | ACETAMIDE THIENOTRIAZOLODIAZEPINES AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2021-04-01 | — | — | US | disclosed |
| EP-2966108-B1 | CATALYSTS AND METHODS FOR POLYMER SYNTHESIS | SAUDI ARAMCO TECH CO (SA) | 2021-03-31 | — | — | EP | disclosed |
| US-10959953-B2 | Lipid formulations for delivery of messenger RNA | TRANSLATE BIO, INC. (US) | 2021-03-30 | — | — | US | disclosed |
| US-10961216-B2 | Small molecule modulators of the androgen receptor | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2021-03-30 | — | — | US | disclosed |
| US-10961338-B2 | Bottlebrush polymers and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2021-03-30 | — | — | US | disclosed |
| US-20210087215-A1 | LINCOSAMIDE ANTIBIOTICS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2021-03-25 | — | — | US | disclosed |
| US-20210087202-A1 | HALOGENATED DERIVATIVES OF MORPHINANS AND USES THEREOF | XALUD THERAPEUTICS, INC. (US) | 2021-03-25 | — | — | US | disclosed |
| WO-2021055386-A1 | USE OF THIAZOLE AMIDE COMPOUNDS FOR MODULATING HUMAN IMMUNE RESPONSE | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2021-03-25 | — | — | WO | disclosed |
| EP-3793539-A1 | COMPOUNDS FOR TREATING DENGUE VIRUS INFECTIONS AND OTHER INFECTIONS | Dana-Farber Cancer Institute, Inc. (US) | 2021-03-24 | — | — | EP | disclosed |
| US-10954244-B2 | Compounds and uses thereof | KALA PHARMACEUTICALS, INC. (US) | 2021-03-23 | — | — | US | disclosed |
| US-10954242-B2 | Bicyclic urea kinase inhibitors and uses thereof | THE BROAD INSTITUTE, INC. (US) | 2021-03-23 | — | — | US | disclosed |
| WO-2021050702-A1 | KDM INHIBITORS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2021-03-18 | — | — | WO | disclosed |
| WO-2021050700-A1 | CYCLOOXYGENASE-2 INHIBITORS AND USES THEREOF | THE BROAD INSTITUTE, INC. (US) | 2021-03-18 | — | — | WO | disclosed |
| WO-2021051016-A1 | SYSTEMS AND ASSAYS FOR IDENTIFYING PU.1 INHIBITORS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2021-03-18 | — | — | WO | disclosed |
| US-20210077243-A1 | UROLOGICAL DEVICE INCLUDING A VALVE RETAINED IN A URINARY CATHETER | COLOPLAST A/S (DK) | 2021-03-18 | — | — | US | disclosed |
| US-20210078951-A1 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | Epizyme, Inc. | 2021-03-18 | — | — | US | disclosed |
| EP-2920197-B1 | PROLINE-LOCKED STAPLED PEPTIDES AND USES THEREOF | HARVARD COLLEGE (US) | 2021-03-17 | — | — | EP | disclosed |
| EP-3790968-A1 | OLIGONUCLEOTIDES CONJUGATES COMPRISING 7'-5'-ALPHA-ANOMERIC-BICYCLIC SUGAR NUCLEOSIDES | Alpha Anomeric SAS (FR) | 2021-03-17 | — | — | EP | disclosed |
| US-20210070796-A1 | MINIMAL SAPONIN ANALOGUES, SYNTHESIS AND USE THEREOF | MEMORIAL SLOAN-KETTERING CANCER CENTER | 2021-03-11 | — | — | US | disclosed |
| US-20210069082-A1 | SPIROKETALS AND USES THEREOF | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2021-03-11 | — | — | US | disclosed |
| US-20210070775-A1 | Antitumoral Compounds | PHARMA MAR, S.A. (ES) | 2021-03-11 | — | — | US | disclosed |
| WO-2021043951-A1 | DRUG ANTIBODY CONJUGATES | PHARMA MAR, S.A. (ES) | 2021-03-11 | — | — | WO | disclosed |
| EP-3787612-A1 | CANCER TREATMENTS TARGETING CANCER STEM CELLS | Remedy Plan, Inc. (US) | 2021-03-10 | — | — | EP | disclosed |
| US-10941429-B2 | Enzymatic synthesis of kavalactones and flavokavains | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2021-03-09 | — | — | US | disclosed |
| US-20210062195-A1 | RNA INTERFERENCE IN OCULAR INDICATIONS | PHIO PHARMACEUTICALS CORP. (US) | 2021-03-04 | — | — | US | disclosed |
| EP-3041484-B1 | HUMAN INKT CELL ACTIVATION USING GLYCOLIPIDS WITH ALTERED GLYCOSYL GROUPS | ACADEMIA SINICA (TW) | 2021-03-03 | — | — | EP | disclosed |
| CN-108135923-B | Nucleic acid molecules targeting superoxide dismutase 1(SOD1) | 菲奥医药公司 | 2021-03-02 | — | — | CN | disclosed |
| US-10933139-B2 | Conjugated lipomers and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2021-03-02 | — | — | US | disclosed |
| US-20210053955-A1 | GHRELIN O-ACYLTRANSFERASE INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2021-02-25 | — | — | US | disclosed |
| EP-3782638-A1 | STAPLED AND STITCHED POLYPEPTIDES AND USES THEREOF | President and Fellows of Harvard College (US) | 2021-02-24 | — | — | EP | disclosed |
| US-10927138-B2 | Inhibitors of D-amino acid oxidase (DAAO) and uses thereof | SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) | 2021-02-23 | — | — | US | disclosed |
| EP-3774767-A1 | ARYL HYDROCARBON RECEPTOR MODULATORS AND USES THEREOF | Beth Israel Deaconess Medical Center, Inc. (US) | 2021-02-17 | — | — | EP | disclosed |
| EP-3774986-A1 | BRUSH PRODRUGS AND USES THEREOF | Massachusetts Institute of Technology (US) | 2021-02-17 | — | — | EP | disclosed |
| EP-3773683-A1 | AZIDE INSULIN ANALOGUES | Merck Sharp&Dohme Corp. (US) | 2021-02-17 | — | — | EP | disclosed |
| EP-2691443-B1 | CONJUGATED LIPOMERS AND USES THEREOF | MASSACHUSETTS INST TECHNOLOGY (US) | 2021-02-17 | — | — | EP | disclosed |
| EP-2841066-B1 | ANTI-INFLUENZA AGENT CONJUGATED TO ANTI-INFLAMMATORY AGENT | ACADEMIA SINICA (TW) | 2021-02-17 | — | — | EP | disclosed |
| US-10919936-B2 | — | — | 2021-02-16 | — | — | US | disclosed |
| US-10918714-B2 | Human iNKT cell activation using glycolipids with altered glycosyl groups | ACADEMIA SINICA (TW) | 2021-02-16 | — | — | US | disclosed |
| WO-2021023646-A1 | MELANOCYTE-REGULATING PEPTIDES | IDP DISCOVERY PHARMA, S.L. (ES) | 2021-02-11 | — | — | WO | disclosed |
| US-20210040099-A1 | Compounds for the Treatment of Kinase-Dependent Disorders | EXELIXIS, INC. | 2021-02-11 | — | — | US | disclosed |
| US-20210040141-A1 | 3,3 DISUBSTITUTED 19-NOR PREGNANE COMPOUNDS, COMPOSITIONS, AND USES THEREOF | SAGE THERAPEUTICS, INC. | 2021-02-11 | — | — | US | disclosed |
| WO-2021023609-A1 | COMBINATION OF A TYPE I PROTEIN ARGININE METHYLTRANSFERASE (TYPE I PRMT) INHIBITOR AND A METHIONINE ADENOSYLTRANSFERASE II ALPHA (MAT2A) INHIBITOR | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2021-02-11 | — | — | WO | disclosed |
| US-20210040076-A1 | Compounds for the Treatment of Kinase-Dependent Disorders | EXELIXIS, INC. | 2021-02-11 | — | — | US | disclosed |
| US-10913764-B2 | Macrolides and methods of their preparation and use | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2021-02-09 | — | — | US | disclosed |
| US-10913752-B2 | Bivalent bromodomain inhibitors and uses thereof | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2021-02-09 | — | — | US | disclosed |
| US-10913948-B2 | RNA interference in dermal and fibrotic indications | PHIO PHARMACEUTICALS CORP. (US) | 2021-02-09 | — | — | US | disclosed |
| US-10912844-B2 | Biodegradable lipids for delivery of nucleic acids | TRANSLATE BIO, INC. (US) | 2021-02-09 | — | — | US | disclosed |
| WO-2021021979-A2 | HDAC6 INHIBITORS AND USES THEREOF | EIKONIZO THERAPAPEUTICS, INC. (US) | 2021-02-04 | — | — | WO | disclosed |
| US-20210032620-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2021-02-04 | — | — | US | disclosed |
| US-20210032263-A1 | Compounds for the Treatment of Kinase-Dependent Disorders | EXELIXIS, INC. | 2021-02-04 | — | — | US | disclosed |
| US-10906889-B2 | Polycyclic inhibitors of cyclin-dependent kinase 7 (CDK7) | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2021-02-02 | — | — | US | disclosed |
| US-10906926-B2 | Triterpene saponin analogues | ADJUVANCE TECHNOLOGIES, INC. (US) | 2021-02-02 | — | — | US | disclosed |
| US-20210023224-A1 | BRANCHED MULTI-FUNCTIONAL MACROMONOMERS AND RELATED POLYMERS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2021-01-28 | — | — | US | disclosed |
| WO-2021016388-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2021-01-28 | — | — | WO | disclosed |
| EP-3768291-A1 | TYROSINE-SPECIFIC FUNCTIONALIZED INSULIN AND INSULIN ANALOGS | Merck Sharp&Dohme Corp. (US) | 2021-01-27 | — | — | EP | disclosed |
| US-10900039-B2 | Methods for treating aging and skin disorders using nucleic acids targeting Tyr or MMP1 | PHIO PHARMACEUTICALS CORP. (US) | 2021-01-26 | — | — | US | disclosed |
| US-20210015930-A1 | PHOSPHONATE LINKERS AND THEIR USE TO FACILITATE CELLULAR RETENTION OF COMPOUNDS | MERCK SHARP & DOHME CORP. (US) | 2021-01-21 | — | — | US | disclosed |
| EP-3092220-B1 | VITAMIN C PRODRUGS AND USES THEREOF | UNIV FLORIDA (US) | 2021-01-20 | — | — | EP | disclosed |
| US-20210008159-A1 | PEPTIDES WITH ANTI-CANCER ACTIVITY | IDP DISCOVERY PHARMA S L (ES) | 2021-01-14 | — | — | US | disclosed |
| US-20210009605-A1 | CHROMIUM-MEDIATED COUPLING AND APPLICATION TO THE SYNTHESIS OF HALICHONDRINS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2021-01-14 | — | — | US | disclosed |
| EP-3763710-A1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | Kala Pharmaceuticals, Inc. (US) | 2021-01-13 | — | — | EP | disclosed |
| US-20210000119-A1 | SYNTHESIS AND ANTI-CANCER ACTIVITY OF COMMUNESIN ALKALOIDS | MASSACHUSETTS INST TECHNOLOGY (US) | 2021-01-07 | — | — | US | disclosed |
| WO-2021003050-A2 | CD38-BINDING AGENTS AND USES THEREOF | KLEO PHARMACEUTICALS, INC. (US) | 2021-01-07 | — | — | WO | disclosed |
| US-20210002316-A1 | TRITERPENE SAPONIN ANALOGUES | ADJUVANCE TECHNOLOGIES, INC. (US) | 2021-01-07 | — | — | US | disclosed |
| US-20210002345-A1 | TYROSINE-SPECIFIC FUNCTIONALIZED INSULIN AND INSULIN ANALOGS | MERCK SHARP & DOHME CORP. (US) | 2021-01-07 | — | — | US | disclosed |
| US-10882884-B2 | Stereoselective synthesis of phosphorothioate oligoribonucleotides | ETH ZURICH (CH) | 2021-01-05 | — | — | US | disclosed |
| US-10881668-B2 | Acetamide thienotriazolodiazepines and uses thereof | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2021-01-05 | — | — | US | disclosed |
| US-20200407371-A1 | SMALL MOLECULES FOR INDUCING SELECTIVE PROTEIN DEGRADATION AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2020-12-31 | — | — | US | disclosed |
| EP-3755377-A1 | SMALL MOLECULES THAT BLOCK PROTEASOME-ASSOCIATED UBIQUITIN RECEPTOR RPN13 FUNCTION AND USES THEREOF | Dana-Farber Cancer Institute, Inc. (US) | 2020-12-30 | — | — | EP | disclosed |
| EP-3755325-A1 | SMALL MOLECULES FOR INDUCING SELECTIVE PROTEIN DEGRADATION AND USES THEREOF | Dana-Farber Cancer Institute, Inc. (US) | 2020-12-30 | — | — | EP | disclosed |
| WO-2020263935-A1 | HCK DEGRADERS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2020-12-30 | — | — | WO | disclosed |
| US-10874500-B2 | Urological device adapted for placement in a urethra of a user for treatment of incontinence | COLOPLAST A/S (DK) | 2020-12-29 | — | — | US | disclosed |
| US-10874686-B2 | Anthranilyl-adenosinemonosulfamate analogs and uses thereof | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2020-12-29 | — | — | US | disclosed |
| US-20200397927-A1 | COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS | LANTHEUS MEDICAL IMAGING, INC. (US) | 2020-12-24 | — | — | US | disclosed |
| US-20200399634-A1 | DNA-TEMPLATED MACROCYCLE LIBRARY | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2020-12-24 | — | — | US | disclosed |
| EP-3341007-B1 | MALT1 INHIBITORS AND USES THEREOF | UNIV CORNELL (US) | 2020-12-23 | — | — | EP | disclosed |
| EP-3319614-B1 | NUCLEIC ACID MOLECULES TARGETING SUPEROXIDE DISMUTASE 1 (SOD1) | PHIO PHARM CORP (US) | 2020-12-23 | — | — | EP | disclosed |
| US-10869929-B2 | Phosphonate linkers and their use to facilitate cellular retention of compounds | MERCK SHARP & DOHME CORP. (US) | 2020-12-22 | — | — | US | disclosed |
| US-10869874-B2 | Methods and compositions for topical delivery of prostaglandins to subcutaneous fat | TOPOKINE THERAPEUTICS, INC. (US) | 2020-12-22 | — | — | US | disclosed |
| US-20200390792-A1 | MODIFIED OLIGOMERIC COMPOUNDS COMPRISING TRICYCLO-DNA NUCLEOSIDES AND USES THEREOF | SYNTHENA AG (CH) | 2020-12-17 | — | — | US | disclosed |
| EP-3749304-A1 | GHRELIN O-ACYLTRANSFERASE INHIBITORS | GlaxoSmithKline Intellectual Property Development Limited (GB) | 2020-12-16 | — | — | EP | disclosed |
| US-10865213-B2 | Max binders as MYC modulators and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2020-12-15 | — | — | US | disclosed |
| US-20200385405-A1 | INHIBITORS OF MALT1 AND USES THEREOF | CORNELL UNIVERSITY (US) | 2020-12-10 | — | — | US | disclosed |
| US-20200384137-A1 | 18F LABELING OF PROTEINS USING SORTASES | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2020-12-10 | — | — | US | disclosed |
| US-20200385407-A1 | COMPOUNDS, CONJUGATES, AND COMPOSITIONS OF EPIPOLYTHIODIKETOPIPERAZINES AND POLYTHIODIKETOPIPERAZINES AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2020-12-10 | — | — | US | disclosed |
| WO-2020247418-A1 | COMPOUNDS FOR THE TREATMENT OF KINASE-DEPENDENT DISORDERS | EXELIXIS, INC. (US) | 2020-12-10 | — | — | WO | disclosed |
| EP-3746496-A1 | CATIONIC POLYMERS | Translate Bio, Inc. (US) | 2020-12-09 | — | — | EP | disclosed |
| US-10856964-B2 | Valve insertable into a body lumen | COLOPLAST A/S (DE) | 2020-12-08 | — | — | US | disclosed |
| US-20200377542-A1 | MACROLIDES WITH MODIFIED DESOSAMINE SUGARS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2020-12-03 | — | — | US | disclosed |
| EP-3743070-A1 | COMPOUNDS FOR THE TREATMENT OF KINASE-DEPENDENT DISORDERS | Exelixis, Inc. (US) | 2020-12-02 | — | — | EP | disclosed |
| EP-3743068-A1 | COMPOUNDS FOR THE TREATMENT OF KINASE-DEPENDENT DISORDERS | Exelixis, Inc. (US) | 2020-12-02 | — | — | EP | disclosed |
| EP-3743417-A1 | COMPOUNDS FOR THE TREATMENT OF KINASE-DEPENDENT DISORDERS | Exelixis, Inc. (US) | 2020-12-02 | — | — | EP | disclosed |
| US-20200369685-A1 | BORONIC ESTER PRODRUGS AND USES THEREOF | MASSACHUSETTS INST TECHNOLOGY (US) | 2020-11-26 | — | — | US | disclosed |
| US-20200369639-A1 | TRICYCLO-DNA NUCLEOSIDE PRECURSORS AND PROCESSES FOR PREPARING THE SAME | SYNTHENA AG (CH) | 2020-11-26 | — | — | US | disclosed |
| US-20200369583-A1 | PROCESS FOR DEOXYFLUORINATION OF PHENOLS | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2020-11-26 | — | — | US | disclosed |
| WO-2020236253-A1 | BORONIC ESTER PRODRUGS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2020-11-26 | — | — | WO | disclosed |
| EP-3740472-A1 | TRICYCLO-DNA NUCLEOSIDE PRECURSORS AND PROCESSES FOR PREPARING THE SAME | Synthena AG (CH) | 2020-11-25 | — | — | EP | disclosed |
| EP-3411034-B1 | SELECTIVE ESTROGEN RECEPTOR DEGRADERS AND USES THEREOF | INVENTISBIO INC (KY) | 2020-11-25 | — | — | EP | disclosed |
| US-10844073-B2 | Palladium-mediated ketolization | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2020-11-24 | — | — | US | disclosed |
| US-10844028-B2 | Aminoalcohol lipidoids and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2020-11-24 | — | — | US | disclosed |
| US-10844077-B2 | Thiazolyl-containing compounds for treating proliferative diseases | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2020-11-24 | — | — | US | disclosed |
| US-20200362095-A1 | BOTTLEBRUSH COPOLYMERS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2020-11-19 | — | — | US | disclosed |
| US-20200361980-A1 | 14-MEMBERED KETOLIDES AND METHODS OF THEIR PREPARATION AND USE | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2020-11-19 | — | — | US | disclosed |
| US-20200362337-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2020-11-19 | — | — | US | disclosed |
| US-20200361906-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASE 12 (CDK12) AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2020-11-19 | — | — | US | disclosed |
| US-20200360381-A1 | COMPOUNDS FOR TREATING DENGUE VIRUS INFECTION AND OTHER VIRAL INFECTIONS | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2020-11-19 | — | — | US | disclosed |
| EP-3171874-B1 | IMIDAZOLYL KINASE INHIBITORS AND USES THEREOF | DANA FARBER CANCER INST INC (US) | 2020-11-18 | — | — | EP | disclosed |
| EP-3737362-A1 | COMBINATION OF A SELECTIVE HISTONE DEACETYLASE 3 (HDAC3) INHIBITOR AND AN IMMUNOTHERAPY AGENT FOR THE TREATMENT OF CANCER | KDAC THERAPEUTICS, INC. (US) | 2020-11-18 | — | — | EP | disclosed |
| US-10836859-B2 | Polycarbonate polyol compositions and methods | SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) | 2020-11-17 | — | — | US | disclosed |
| US-20200353099-A1 | ALKENYL SUBSTITUTED 2,5-PIPERAZINEDIONES, COMPOSITIONS, AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2020-11-12 | — | — | US | disclosed |
| WO-2020227691-A2 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2020-11-12 | — | — | WO | disclosed |
| US-10828367-B2 | Photoswitchable HDAC inhibitors | THE GENERAL HOSPITAL CORPORATION (US) | 2020-11-10 | — | — | US | disclosed |
| US-20200345856-A1 | CONJUGATES OF TUMOR NECROSIS FACTOR INHIBITORS TO FUNCTIONALIZED POLYMERS | FISH & RICHARDSON PC | 2020-11-05 | — | — | US | disclosed |
| US-20200347087-A1 | SYNTHESIS OF DESOSAMINES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2020-11-05 | — | — | US | disclosed |
| US-20200338087-A9 | USES OF SALT-INDUCIBLE KINASE (SIK) INHIBITORS | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2020-10-29 | — | — | US | disclosed |
| US-20200339620-A1 | LINCOSAMIDE ANTIBIOTICS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2020-10-29 | — | — | US | disclosed |
| US-20200338075-A1 | 4,6-PYRIMIDINYLENE DERIVATIVES AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2020-10-29 | — | — | US | disclosed |
| US-20200338074-A1 | COMBINATION THERAPY OF TRANSCRIPTION INHIBITORS AND KINASE INHIBITORS | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2020-10-29 | — | — | US | disclosed |
| WO-2020219650-A1 | DEGRADERS OF CYCLIN-DEPENDENT KINASE 12 (CDK12) AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2020-10-29 | — | — | WO | disclosed |
| WO-2020219983-A2 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2020-10-29 | — | — | WO | disclosed |
| WO-2020219981-A2 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2020-10-29 | — | — | WO | disclosed |
| US-10815184-B2 | Co-crystals of lithium benzoate and uses thereof | SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) | 2020-10-27 | — | — | US | disclosed |
| US-10815482-B2 | Chiral design | WAVE LIFE SCIENCES LTD. (SG) | 2020-10-27 | — | — | US | disclosed |
| CN-111825611-A | 4(1H) -quinovone derivatives and uses thereof | 中央研究院 | 2020-10-27 | — | — | CN | disclosed |
| US-20200331894-A1 | D-AMINO ACID OXIDASE INHIBITORS AND THERAPEUTIC USES THEREOF | SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) | 2020-10-22 | — | — | US | disclosed |
| US-20200330449-A1 | 4(1H)-QUINOLONE DERIVATIVES AND USES THEREOF | ACADEMIA SINICA (TW) | 2020-10-22 | — | — | US | disclosed |
| US-20200330501-A1 | AMINO ACID-, PEPTIDE- AND POLYPEPTIDE-LIPIDS, ISOMERS, COMPOSITIONS, AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2020-10-22 | — | — | US | disclosed |
| EP-3077050-B1 | METHODS FOR TREATMENT OF WOUND HEALING UTILIZING CHEMICALLY MODIFIED OLIGONUCLEOTIDES | PHIO PHARM CORP (US) | 2020-10-21 | — | — | EP | disclosed |
| EP-3723749-A1 | HALOGENATED DERIVATIVES OF MORPHINANS AND USES THEREOF | Xalud Therapeutics, Inc. (US) | 2020-10-21 | — | — | EP | disclosed |
| US-10808247-B2 | Methods for treating neurological disorders using a synergistic small molecule and nucleic acids therapeutic approach | PHIO PHARMACEUTICALS CORP. (US) | 2020-10-20 | — | — | US | disclosed |
| US-10806796-B2 | Conjugates of biologically active molecules to functionalized polymers | QUIAPEG PHARMACEUTICALS AB (SE) | 2020-10-20 | — | — | US | disclosed |
| US-20200323854-A1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | KALA BIO, Inc. | 2020-10-15 | — | — | US | disclosed |
| US-20200325152-A1 | MACROCYCLIC COMPOUNDS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2020-10-15 | — | — | US | disclosed |
| US-10800743-B2 | Arginine methyltransferase inhibitors and uses thereof | Epizyme, Inc. (US) | 2020-10-13 | — | — | US | disclosed |
| US-10799594-B2 | Drug delivery polymer and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2020-10-13 | — | — | US | disclosed |
| US-20200316069-A1 | CYTOSINE-BASED TET ENZYME INHIBITORS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2020-10-08 | — | — | US | disclosed |
| US-20200317675-A9 | BICYCLIC UREA KINASE INHIBITORS AND USES THEREOF | THE BROAD INSTITUTE, INC. (US) | 2020-10-08 | — | — | US | disclosed |
| US-10792373-B2 | Drug delivery polymers and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2020-10-06 | — | — | US | disclosed |
| US-10793571-B2 | Uses of diazepane derivatives | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2020-10-06 | — | — | US | disclosed |
| US-10793683-B2 | Block co-poly(metal organic nanostructures) (BCPMONs) and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2020-10-06 | — | — | US | disclosed |
| WO-2020197541-A1 | CYTOSINE-BASED TET ENZYME INHIBITORS | PRESIDENT AND TRUSTEES OF BATES COLLEGE (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2020198367-A1 | COMPOUNDS FOR USES IN PHARMACOLOGICAL INDUCTION OF HBF FOR TREATMENT OF SICKLE CELL DISEASE AND β-THALASSEMIA | ACADEMIA SINICA (TW) | 2020-10-01 | — | — | WO | disclosed |
| US-20200308231-A9 | SOLUTION-PHASE AFFINITY SELECTION OF INHIBITORS FROM COMBINATORIAL PEPTIDE LIBRARIES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2020-10-01 | — | — | US | disclosed |
| EP-3715346-A1 | THIAZOLYL-CONTAINING COMPOUNDS FOR TREATING PROLIFERATIVE DISEASES | Dana-Farber Cancer Institute (US) | 2020-09-30 | — | — | EP | disclosed |
| US-10787436-B2 | Inhibitors of cyclin-dependent kinase 7 (CDK7) | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2020-09-29 | — | — | US | disclosed |
| US-20200299257-A9 | INHIBITORS OF INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASES AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2020-09-24 | — | — | US | disclosed |
| US-20200299228-A1 | PROCESSES FOR THE PREPARATION OF (S)-TERT-BUTYL 4,5-DIAMINO-5-OXOPENTANOATE | CELGENE CORPORATION | 2020-09-24 | — | — | US | disclosed |
| US-20200299692-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2020-09-24 | — | — | US | disclosed |
| US-20200299272-A1 | Urea Derivatives and Uses Thereof | KALA BIO, Inc. | 2020-09-24 | — | — | US | disclosed |
| WO-2020191183-A1 | MULTIVALENT LIGAND CLUSTERS FOR TARGETED DELIVERY OF THERAPEUTIC AGENTS | MITOTHERAPEUTIX LLC (US) | 2020-09-24 | — | — | WO | disclosed |
| WO-2020191252-A1 | TECHNOLOGIES USEFUL FOR OLIGONUCLEOTIDE PREPARATION | WAVE LIFE SCIENCES LTD. (SG) | 2020-09-24 | — | — | WO | disclosed |
| EP-2970132-B1 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | EPIZYME INC (US) | 2020-09-23 | — | — | EP | disclosed |
| EP-3710454-A1 | MACROCYCLIC COMPOUNDS AND USES THEREOF | President And Fellows Of Harvard College (US) | 2020-09-23 | — | — | EP | disclosed |
| EP-3709998-A1 | NOVEL IMIDAZOPYRIMIDINE COMPOUNDS AND USES THEREOF | Children's Medical Center Corporation (US) | 2020-09-23 | — | — | EP | disclosed |
| EP-3710007-A1 | USE OF IMIDAZOPYRIMIDINE FOR MODULATING HUMAN IMMUNE RESPONSE | Children's Medical Center Corporation (US) | 2020-09-23 | — | — | EP | disclosed |
| US-10781286-B2 | Functionalized polymers | QUIAPEG PHARMACEUTICALS AB (SE) | 2020-09-22 | — | — | US | disclosed |
| US-20200289469-A1 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | Epizyme, Inc. | 2020-09-17 | — | — | US | disclosed |
| EP-2673293-B1 | SURROGATES OF POST-TRANSLATIONALLY MODIFIED PROTEINS AND USES THEREOF | HARVARD COLLEGE (US) | 2020-09-16 | — | — | EP | disclosed |
| US-20200282059-A1 | COMPOSITIONS AND METHODS FOR TOPICAL DELIVERY OF PROSTAGLANDINS TO SUBCUTANEOUS FAT | TOPOKINE THERAPEUTICS, INC. (US) | 2020-09-10 | — | — | US | disclosed |
| US-20200282048-A1 | USE OF IMIDAZOPYRIMIDINE FOR MODULATING HUMAN IMMUNE RESPONSE | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2020-09-10 | — | — | US | disclosed |
| EP-3703760-A1 | GENE DELIVERY CARRIER | Massachusetts Institute Of Technology (US) | 2020-09-09 | — | — | EP | disclosed |
| US-10765681-B2 | Purine compounds possessing anticancer activity | ACADEMIA SINICA (TW) | 2020-09-08 | — | — | US | disclosed |
| US-10765651-B2 | Co-crystals of substituted glycine and uses thereof | SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) | 2020-09-08 | — | — | US | disclosed |
| US-20200277292-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASES | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2020-09-03 | — | — | US | disclosed |
| US-10759828-B2 | Neuroactive steroids, compositions, and uses thereof | SAGE THERAPEUTICS, INC. (US) | 2020-09-01 | — | — | US | disclosed |
| US-10758539-B2 | Therapeutic compounds and uses thereof | KALA PHARMACEUTICALS, INC. (US) | 2020-09-01 | — | — | US | disclosed |
| US-10759764-B2 | Fluorination of organic compounds | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2020-09-01 | — | — | US | disclosed |
| US-20200268691-A1 | USE OF METFORMIN AND ANALOGS THEREOF TO REDUCE RAN PROTEIN LEVELS IN THE TREATMENT OF NEUROLOGICAL DISORDERS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2020-08-27 | — | — | US | disclosed |
| US-RE48175-E1 | Hydrophobically tagged small molecules as inducers of protein degradation | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2020-08-25 | — | — | US | disclosed |
| EP-2958895-B1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | KALA PHARMACEUTICALS INC (US) | 2020-08-19 | — | — | EP | disclosed |
| US-20200253981-A1 | USES OF PYRIMIDOPYRIMIDINONES AS SIK INHIBITORS | THE GENERAL HOSPITAL CORPORATION (US) | 2020-08-13 | — | — | US | disclosed |
| WO-2020163673-A1 | INHIBITORS OF ADENYLATE-FORMING ENZYME MENE | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2020-08-13 | — | — | WO | disclosed |
| US-20200255447-A1 | THIENOPYRIMIDINES AND USES THEREOF | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2020-08-13 | — | — | US | disclosed |
| US-10736966-B2 | Brush-poly (glycoamidoamine)-lipids and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2020-08-11 | — | — | US | disclosed |
| EP-3688021-A1 | USE OF METFORMIN AND ANALOGS THEREOF TO REDUCE RAN PROTEIN LEVELS IN THE TREATMENT OF NEUROLOGICAL DISORDERS | University of Florida Research Foundation, Incorporated (US) | 2020-08-05 | — | — | EP | disclosed |
| US-10730860-B2 | Diaminopyrimidine benzenesulfone derivatives and uses thereof | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2020-08-04 | — | — | US | disclosed |
| US-20200239509-A1 | TRITERPENE SAPONIN ANALOGUES | ADJUVANCE TECHNOLOGIES, INC. (US) | 2020-07-30 | — | — | US | disclosed |
| US-20200239547-A1 | ANTICANCER PEPTIDES | IDP DISCOVERY PHARMA, S.L. (ES) | 2020-07-30 | — | — | US | disclosed |
| US-20200239463-A1 | INHIBITORS OF PLASMA KALLIKREIN AND USES THEREOF | DYAX CORP. (US) | 2020-07-30 | — | — | US | disclosed |
| US-10723753-B2 | Ras inhibitors and uses thereof | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2020-07-28 | — | — | US | disclosed |
| US-10724035-B2 | Oligonucleotide compositions and methods thereof | WAVE LIFE SCIENCES LTD. (SG) | 2020-07-28 | — | — | US | disclosed |
| US-10723719-B2 | Urea derivatives and uses thereof | KALA PHARMACEUTICALS, INC. (US) | 2020-07-28 | — | — | US | disclosed |
| US-20200230264-A1 | COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS | LANTHEUS MEDICAL IMAGING, INC. (US) | 2020-07-23 | — | — | US | disclosed |
| EP-3357931-B1 | METHODS OF SYNTHESIS OF TRITERPENE PROSAPOGENINS AND TRITERPENE SAPONINS | SLOAN KETTERING INST CANCER RES (US) | 2020-07-22 | — | — | EP | disclosed |
| US-10716858-B2 | Branched multi-functional macromonomers and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2020-07-21 | — | — | US | disclosed |
| US-10717703-B2 | Processes for the preparation of (S)-tert-butyl 4,5-diamino-5-oxopentanoate | CELGENE CORPORATION (US) | 2020-07-21 | — | — | US | disclosed |
| US-20200222546-A1 | CONJUGATES OF BIOLOGICALLY ACTIVE MOLECULES TO FUNCTIONALIZED POLYMERS | QUIAPEG AB (SE) | 2020-07-16 | — | — | US | disclosed |
| US-20200222558-A1 | BIODEGRADABLE LIPIDS FOR DELIVERY OF NUCLEIC ACIDS | RANA THERAPEUTICS, INC. | 2020-07-16 | — | — | US | disclosed |
| US-20200223863-A1 | SYNTHESIS OF HALICHONDRIN ANALOGS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2020-07-16 | — | — | US | disclosed |
| US-20200222447-A9 | BIO-INSPIRED POLYMERS FOR USE AS SYNTHETIC MUCINS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2020-07-16 | — | — | US | disclosed |
| US-20200223884-A1 | 3,3 DISUBSTITUTED 19-NOR PREGNANE COMPOUNDS, COMPOSITIONS, AND USES THEREOF | SAGE THERAPEUTICS INC (US) | 2020-07-16 | — | — | US | disclosed |
| WO-2020086965-A9 | POLYMER-LIPIDS AND COMPOSITIONS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2020-07-16 | — | — | WO | disclosed |
| WO-2020146561-A1 | DOT1L DEGRADERS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2020-07-16 | — | — | WO | disclosed |
| US-10711036-B2 | MALT1 inhibitors and uses thereof | CORNELL UNIVERSITY (US) | 2020-07-14 | — | — | US | disclosed |
| US-20200215113-A1 | CHEMICALLY MODIFIED OLIGONUCLEOTIDES | PHIO PHARMACEUTICALS CORP. (US) | 2020-07-09 | — | — | US | disclosed |
| EP-3676267-A1 | INHIBITORS OF EGFR AND/OR HER2 AND METHODS OF USE | Dana Farber Cancer Institute, Inc. (US) | 2020-07-08 | — | — | EP | disclosed |
| EP-3138831-B1 | SYNTHESIS OF TETRACYCLINES AND ANALOGUES THEREOF | HARVARD COLLEGE (US) | 2020-07-08 | — | — | EP | disclosed |
| US-10702527-B2 | Combination therapy of transcription inhibitors and kinase inhibitors | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2020-07-07 | — | — | US | disclosed |
| US-20200206362-A1 | COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS | Moderna TX, Inc. (US) | 2020-07-02 | — | — | US | disclosed |
| WO-2020140098-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2020-07-02 | — | — | WO | disclosed |
| EP-3137119-B1 | METHODS FOR TREATING CANCER USING A NUCLEIC ACID TARGETING MDM2 | PHIO PHARM CORP (US) | 2020-07-01 | — | — | EP | disclosed |
| US-10695346-B2 | 4,6-pyrimidinylene derivatives and uses thereof | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2020-06-30 | — | — | US | disclosed |
| US-10695444-B2 | Alkenyl substituted 2,5-piperazinediones, compositions, and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2020-06-30 | — | — | US | disclosed |
| US-20200199085-A1 | FUNCTIONALIZED 1,2,4,5-TETRAZINE COMPOUNDS FOR USE IN BIOORTHOGONAL COUPLING REACTIONS | THE GENERAL HOSPITAL CORPORATION | 2020-06-25 | — | — | US | disclosed |
| US-20200199078-A1 | COMPOUNDS FOR TREATING PROLIFERATIVE DISEASES | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2020-06-25 | — | — | US | disclosed |
| WO-2020132603-A2 | SALICYL-ADENOSINEMONOSULFAMATE ANALOGS AND USES THEREOF | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2020-06-25 | — | — | WO | disclosed |
| US-20200199150-A1 | CYANO THIENOTRIAZOLODIAZEPINES AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2020-06-25 | — | — | US | disclosed |
| US-20200199121-A1 | INHIBITORS OF EGFR AND/OR HER2 AND METHODS OF USE | DANA-FARBER CANCER INSTITUTE, INC. | 2020-06-25 | — | — | US | disclosed |
| US-10689366-B2 | Compounds for MALT1 degredation | CORNELL UNIVERSITY (US) | 2020-06-23 | — | — | US | disclosed |
| WO-2020123925-A1 | PYRAZOLOPYRIDINE INHIBITORS OF C-JUN-N-TERMINAL KINASES AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2020-06-18 | — | — | WO | disclosed |
| EP-3664815-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | Wave Life Sciences Ltd. (SG) | 2020-06-17 | — | — | EP | disclosed |
| EP-3664817-A1 | CHEMICALLY MODIFIED OLIGONUCLEOTIDES | Phio Pharmaceuticals Corp. (US) | 2020-06-17 | — | — | EP | disclosed |
| EP-3664799-A1 | LINCOSAMIDE ANTIBIOTICS AND USES THEREOF | President And Fellows Of Harvard College (US) | 2020-06-17 | — | — | EP | disclosed |
| EP-3664816-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | Wave Life Sciences Ltd. (SG) | 2020-06-17 | — | — | EP | disclosed |
| US-10683379-B2 | Polymers, hydrogels, and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2020-06-16 | — | — | US | disclosed |
| US-10683387-B2 | Bottlebrush copolymers and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2020-06-16 | — | — | US | disclosed |
| US-10682374-B2 | Amino acid-, peptide- and polypeptide-lipids, isomers, compositions, and uses thereof | MASSACHUSETTS INTSTITUTE OF TECHNOLOGY (US) | 2020-06-16 | — | — | US | disclosed |
| US-20200179387-A1 | USES OF SALT-INDUCIBLE KINASE (SIK) INHIBITORS FOR TREATING OSTEOPOROSIS | THE GENERAL HOSPITAL CORPORATION (US) | 2020-06-11 | — | — | US | disclosed |
| US-20200179531-A1 | METHODS FOR ASSEMBLING SCAVENGING PARTICLES | NANOTICS, LLC | 2020-06-11 | — | — | US | disclosed |
| EP-2016044-B1 | PENTACYCLINE DERIVATIVES FOR THE TREATMENT OF INFECTIONS | HARVARD COLLEGE (US) | 2020-06-10 | — | — | EP | disclosed |
| EP-3661957-A1 | ANTICANCER PEPTIDES | IDP Discovery Pharma, S.L. (ES) | 2020-06-10 | — | — | EP | disclosed |
| EP-3661947-A1 | ANTICANCER PEPTIDES | IDP Discovery Pharma, S.L. (ES) | 2020-06-10 | — | — | EP | disclosed |
| EP-3661922-A1 | INHIBITORS OF PLASMA KALLIKREIN AND USES THEREOF | Dyax Corp. (US) | 2020-06-10 | — | — | EP | disclosed |
| EP-3661898-A1 | PROCESS FOR DEOXYFLUORINATION OF PHENOLS | Studiengesellschaft Kohle MbH (DE) | 2020-06-10 | — | — | EP | disclosed |
| US-20200172553-A9 | BIVALENT BROMODOMAIN INHIBITORS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2020-06-04 | — | — | US | disclosed |
| US-20200172499-A9 | INHIBITORS OF CYCLIN-DEPENDENT KINASES | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2020-06-04 | — | — | US | disclosed |
| US-20200172663-A1 | POLYMER-LIPIDS AND COMPOSITIONS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2020-06-04 | — | — | US | disclosed |
| EP-3658576-A1 | ANTICANCER PEPTIDES | IDP Discovery Pharma, S.L. (ES) | 2020-06-03 | — | — | EP | disclosed |
| US-10669244-B2 | Synthesis of tetracyclines and analogues thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2020-06-02 | — | — | US | disclosed |
| US-20200165267-A1 | THIAZOLYL-CONTAINING COMPOUNDS FOR TREATING PROLIFERATIVE DISEASES | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2020-05-28 | — | — | US | disclosed |
| US-20200165183-A1 | FE/CU-MEDIATED KETONE SYNTHESIS | President and Fellows of Flarvard College (US) | 2020-05-28 | — | — | US | disclosed |
| US-20200164353-A1 | COMPOSITIONS AND METHODS FOR SELECTIVE CARBONYLATION OF HETEROCYCLIC COMPOUNDS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2020-05-28 | — | — | US | disclosed |
| US-20200164065-A1 | TRITERPENE SAPONIN ANALOGUES | ADJUVANCE TECHNOLOGIES, INC. (US) | 2020-05-28 | — | — | US | disclosed |
| US-10662211-B2 | Catalysts and methods for polymer synthesis | Saurdi Aramco Technologies Company (SA) | 2020-05-26 | — | — | US | disclosed |
| US-10662430-B2 | RNA interference in ocular indications | PHIO PHARMACEUTICALS CORP. (US) | 2020-05-26 | — | — | US | disclosed |
| US-20200157150-A1 | ANTICANCER PEPTIDES | IDP DISCOVERY PHARMA, S.L. (ES) | 2020-05-21 | — | — | US | disclosed |
| US-20200157545-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2020-05-21 | — | — | US | disclosed |
| US-20200157106-A1 | Novel Compounds and Uses Thereof | KALA BIO, Inc. | 2020-05-21 | — | — | US | disclosed |
| EP-3653621-A1 | APPARATUS FOR SYNTHESIZING THE IMAGING AGENT 4-CHLORO-2-(1,1-DIMETHYLETHYL)-5-[[4-[[2-(FLUORO-[18F])ETHOXY]METHYL]PHENYL]METHOXY]-3(2H)-PYRIDAZINONE (FLUORPIRIDAZ [18F]) | Lantheus Medical Imaging, Inc. (US) | 2020-05-20 | — | — | EP | disclosed |
| EP-3652329-A1 | COMPOUNDS FOR TAU PROTEIN DEGRADATION | Dana-Farber Cancer Institute, Inc. (US) | 2020-05-20 | — | — | EP | disclosed |
| EP-3653230-A1 | COMPOSITIONS, METHODS AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS | Lantheus Medical Imaging, Inc. (US) | 2020-05-20 | — | — | EP | disclosed |
| US-10653790-B2 | Compositions and methods related to scavenger particles | NANOTICS, LLC (US) | 2020-05-19 | — | — | US | disclosed |
| US-10653676-B2 | Small molecule inhibitors of USP1 deubiquitinating enzyme activity | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2020-05-19 | — | — | US | disclosed |
| US-10653788-B2 | Conjugates of tumor necrosis factor inhibitors to functionalized polymers | QUIAPEG PHARMACEUTICALS AB (SE) | 2020-05-19 | — | — | US | disclosed |
| EP-3649135-A1 | SYNTHESIS OF HALICHONDRINS | President and Fellows of Harvard College (US) | 2020-05-13 | — | — | EP | disclosed |
| US-10647683-B2 | Hsp70 modulators and methods for making and using the same | MEMORIAL SLOAN KETTERING CANCER CENTER (US) | 2020-05-12 | — | — | US | disclosed |
| US-10647724-B2 | Selective estrogen receptor degraders and uses thereof | INVENTISBIO INC. (KY) | 2020-05-12 | — | — | US | disclosed |
| US-20200140381-A1 | ANTIFUNGAL COMPOUNDS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2020-05-07 | — | — | US | disclosed |
| EP-3645530-A2 | BRANCHED MULTI-FUNCTIONAL MACROMONOMERS AND RELATED POLYMERS AND USES THEREOF | Massachusetts Institute of Technology (US) | 2020-05-06 | — | — | EP | disclosed |
| EP-3645600-A1 | CORE-TO-SURFACE POLYMERIZATION FOR THE SYNTHESIS OF STAR POLYMERS AND USES THEREOF | Massachusetts Institute of Technology (US) | 2020-05-06 | — | — | EP | disclosed |
| US-10639381-B2 | Trioxacarcins, trioxacarcin#antibody conjugates, and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2020-05-05 | — | — | US | disclosed |
| US-10639348-B2 | Peptides with anti-cancer activity | IDP DISCOVERY PHARMA, S.L. (ES) | 2020-05-05 | — | — | US | disclosed |
| US-10640508-B2 | Diazene directed modular synthesis of compounds with quaternary carbon centers | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2020-05-05 | — | — | US | disclosed |
| US-10640528-B2 | Macrolides with modified desosamine sugars and uses thereof | PRESIDENT AND FELLOWS OF HAVARD COLLEGE (US) | 2020-05-05 | — | — | US | disclosed |
| US-10633371-B2 | EZH2 inhibitors and uses thereof | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2020-04-28 | — | — | US | disclosed |
| US-10633389-B2 | CARM1 inhibitors and uses thereof | Epizyme, Inc. (US) | 2020-04-28 | — | — | US | disclosed |
| US-10633407-B2 | 14-membered ketolides and methods of their preparation and use | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2020-04-28 | — | — | US | disclosed |
| US-10633392-B2 | Chromium-mediated coupling and application to the synthesis of halichondrins | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2020-04-28 | — | — | US | disclosed |
| US-10633348-B2 | Methods to treat lymphoplasmacytic lymphoma | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2020-04-28 | — | — | US | disclosed |
| US-10632103-B2 | Arginine methyltransferase inhibitors and uses thereof | Epizyme, Inc. (US) | 2020-04-28 | — | — | US | disclosed |
| US-20200123297-A1 | BOTTLEBRUSH POLYMERS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2020-04-23 | — | — | US | disclosed |
| WO-2020081572-A1 | TRANSCRIPTIONAL ENHANCED ASSOCIATE DOMAIN (TEAD) TRANSCRIPTION FACTOR INHIBITORS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2020-04-23 | — | — | WO | disclosed |
| US-10626137-B2 | Minimal saponin analogues, synthesis and use thereof | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2020-04-21 | — | — | US | disclosed |
| US-20200109154-A1 | TRICYCLIC COMPOUNDS AS GLYCOGEN SYNTHASE KINASE 3 (GSK3) INHIBITORS AND USES THEREOF | THE BROAD INSTITUTE, INC. (US) | 2020-04-09 | — | — | US | disclosed |
| US-20200109121-A1 | IONIZABLE LIPIDOIDS AND THEIR USES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2020-04-09 | — | — | US | disclosed |
| WO-2020072892-A1 | PI3K INHIBITORS AND USES THEREOF | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2020-04-09 | — | — | WO | disclosed |
| US-20200109420-A1 | REDUCTION OR ELIMINATION OF IMMUNE RESPONSES TO NON-INTRAVENOUS, E.G., SUBCUTANEOUSLY ADMINISTERED THERAPEUTIC PROTEINS | MODERNATX, INC. (US) | 2020-04-09 | — | — | US | disclosed |
| EP-3630199-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | Wave Life Sciences Ltd. (SG) | 2020-04-08 | — | — | EP | disclosed |
| US-10611738-B2 | Functionalized 1,2,4,5-tetrazine compounds for use in bioorthogonal coupling reactions | THE GENERAL HOSPITAL CORPORATION (US) | 2020-04-07 | — | — | US | disclosed |
| EP-3628332-A1 | CONJUGATES OF BIOLOGICALLY ACTIVE MOLECULES TO FUNCTIONALIZED POLYMERS | QuiaPEG Pharmaceuticals AB (SE) | 2020-04-01 | — | — | EP | disclosed |
| WO-2020061300-A1 | NOVEL ANNULATION CATALYSTS VIA DIRECT C-H BOND AMINATION | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2020-03-26 | — | — | WO | disclosed |
| US-20200095233-A1 | 4,9-DIOXO-4,9-DIHYDRONAPHTHO[2,3-B]FURAN-3-CARBOXAMIDE DERIVATIVES AND USES THEREOF FOR TREATING PROLIFERATIVE DISEASES AND INFECTIOUS DISEASES | ACADEMIA SINICA (TW) | 2020-03-26 | — | — | US | disclosed |
| WO-2020061295-A1 | HIGH-PURITY PEG LIPIDS AND USES THEREOF | MODERNATX, INC. (US) | 2020-03-26 | — | — | WO | disclosed |
| WO-2020061284-A1 | PEG LIPIDS AND USES THEREOF | MODERNATX, INC. (US) | 2020-03-26 | — | — | WO | disclosed |
| US-10597387-B2 | Methods to treat lymphoplasmacytic lymphoma | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2020-03-24 | — | — | US | disclosed |
| US-20200087295-A9 | INHIBITORS OF C-JUN-N-TERMINAL KINASE (JNK) | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2020-03-19 | — | — | US | disclosed |
| US-20200085764-A1 | TOPICAL DELIVERY OF NUCLEIC ACID COMPOUNDS | PHIO PHARMACEUTICALS CORP. (US) | 2020-03-19 | — | — | US | disclosed |
| US-20200085817-A1 | KCC2 EXPRESSION ENHANCING COMPOUNDS AND USES THEREOF | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2020-03-19 | — | — | US | disclosed |
| EP-2391218-B1 | CONJUGATE BASED SYSTEMS FOR CONTROLLED DRUG DELIVERY | SMARTCELLS INC (US) | 2020-03-18 | — | — | EP | disclosed |
| US-10590413-B2 | Chiral control | WAVE LIFE SCIENCES LTD. (SG) | 2020-03-17 | — | — | US | disclosed |
| US-20200080083-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2020-03-12 | — | — | US | disclosed |
| US-20200078299-A1 | LIPID FORMULATIONS FOR DELIVERY OF MESSENGER RNA | SHIRE HUMAN GENETIC THERAPIES, INC. | 2020-03-12 | — | — | US | disclosed |
| EP-3209648-B1 | THIAZOLYL-CONTAINING COMPOUNDS FOR TREATING PROLIFERATIVE DISEASES | DANA FARBER CANCER INST INC (US) | 2020-03-11 | — | — | EP | disclosed |
| EP-3620161-A1 | USES OF 4'-DESFERRITHIOCIN ANALOGS | University of Florida Research Foundation, Inc. (US) | 2020-03-11 | — | — | EP | disclosed |
| US-10583119-B2 | Compounds, compositions and methods for making the same | SIGNUM BIOSCIENCES, INC. (US) | 2020-03-10 | — | — | US | disclosed |
| US-20200069811-A1 | PEPTIDE-BASED MULTIPLE-DRUG DELIVERY VEHICLE | ARIEL-UNIVERSITY RESEARCH AND DEVELOPMENT COMPANY LTD. (IL) | 2020-03-05 | — | — | US | disclosed |
| WO-2020047399-A1 | IONIZABLE LIPIDOIDS AND THEIR USES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2020-03-05 | — | — | WO | disclosed |
| WO-2020047251-A1 | O-GLCNAC TRANSFERASE INHIBITORS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2020-03-05 | — | — | WO | disclosed |
| EP-3615544-A1 | ANTITUMORAL COMPOUNDS | Pharma Mar S.A. (ES) | 2020-03-04 | — | — | EP | disclosed |
| US-10577554-B2 | Gas-filled stabilized particles and methods of use | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2020-03-03 | — | — | US | disclosed |
| US-20200061197-A1 | AMINE-CONTAINING TRANSFECTION REAGENTS AND METHODS FOR MAKING AND USING SAME | Life Technologies Corporation | 2020-02-27 | — | — | US | disclosed |
| US-20200061050-A9 | KINASE INHIBITORS AND METHODS OF USE THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2020-02-27 | — | — | US | disclosed |
| US-20200062776-A1 | HEDGEHOG ACYLTRANSFERASE INHIBITORS AND USES THEREOF | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2020-02-27 | — | — | US | disclosed |
| EP-3612546-A1 | MODIFIED OLIGOMERIC COMPOUNDS COMPRISING TRICYCLO-DNA NUCLEOSIDES AND USES THEREOF | Synthena AG (CH) | 2020-02-26 | — | — | EP | disclosed |
| EP-3612152-A1 | TOPICAL DELIVERY OF NUCLEIC ACID COMPOUNDS | Phio Pharmaceuticals Corp. (US) | 2020-02-26 | — | — | EP | disclosed |
| US-10570104-B2 | Metabolically programmed metal chelators and uses thereof | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2020-02-25 | — | — | US | disclosed |
| US-20200056173-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2020-02-20 | — | — | US | disclosed |
| US-20200055814-A1 | ANTI-FIBROTIC COMPOUNDS | SHIRE HUMAN GENETIC THERAPIES, INC. | 2020-02-20 | — | — | US | disclosed |
| US-20200054644-A1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | KALA BIO, Inc. | 2020-02-20 | — | — | US | disclosed |
| US-20200055879-A1 | DEGRADABLE POLYMERS OF A CYCLIC SILYL ETHER AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2020-02-20 | — | — | US | disclosed |
| WO-2020037236-A1 | DEGRADABLE POLYMERS OF A CYCLIC SILYL ETHER AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2020-02-20 | — | — | WO | disclosed |
| WO-2019032619-A9 | CHEMICALLY MODIFIED OLIGONUCLEOTIDES | PHIO PHARMACEUTICALS CORP. (US) | 2020-02-13 | — | — | WO | disclosed |
| WO-2020033377-A1 | HISTONE DEMETHYLASE 5 INHIBITORS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2020-02-13 | — | — | WO | disclosed |
| US-20200048276-A9 | MYC MODULATORS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2020-02-13 | — | — | US | disclosed |
| US-20200046697-A1 | INHIBITOR OF INDOLEAMINE-2,3-DIOXYGENASE (IDO) | INVENTISBIO LLC | 2020-02-13 | — | — | US | disclosed |
| US-20200048250-A1 | SELECTIVE ESTROGEN RECEPTOR DEGRADERS AND USES THEREOF | INVENTISBIO LLC | 2020-02-13 | — | — | US | disclosed |
| EP-3330252-B1 | ISOPRENYL COMPOUNDS AND METHODS THEREOF | SIGNUM BIOSCIENCES INC (US) | 2020-02-12 | — | — | EP | disclosed |
| EP-3607074-A1 | REDUCTION OR ELIMINATION OF IMMUNE RESPONSES TO NON-INTRAVENOUS, E.G., SUBCUTANEOUSLY ADMINISTERED THERAPEUTIC PROTEINS | Modernatx, Inc. (US) | 2020-02-12 | — | — | EP | disclosed |
| EP-3606528-A1 | TRICYCLIC COMPOUNDS AS GLYCOGEN SYNTHASE KINASE 3 (GSK3) INHIBITORS AND USES THEREOF | The Broad Institute, Inc. (US) | 2020-02-12 | — | — | EP | disclosed |
| US-10556910-B2 | Synthesis of halichondrin analogs and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2020-02-11 | — | — | US | disclosed |
| US-10556012-B2 | Compositions and methods for topical delivery of prostaglandins to subcutaneous fat | TOPOKINE THERAPEUTICS, INC. (US) | 2020-02-11 | — | — | US | disclosed |
| US-10556018-B2 | Compositions and methods for delivery of agents | ARES CAPITAL CORPORATION, AS AGENT | 2020-02-11 | — | — | US | disclosed |
| US-10556024-B2 | 18F labeling of proteins using sortases | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2020-02-11 | — | — | US | disclosed |
| US-20200040001-A1 | SELECTIVE ESTROGEN RECEPTOR DEGRADERS AND USES THEREOF | INVENTISBIO LLC | 2020-02-06 | — | — | US | disclosed |
| US-20200039968-A9 | EZH2 INHIBITORS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2020-02-06 | — | — | US | disclosed |
| US-10550190-B2 | Phosphate based linkers for intracellular delivery of drug conjugates | MERCK SHARP & DOHME CORP. (US) | 2020-02-04 | — | — | US | disclosed |
| US-10550121-B2 | Inhibitors of cyclin-dependent kinases | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2020-02-04 | — | — | US | disclosed |
| US-10550079-B2 | Artificial self-sufficient cytochrome P450s | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2020-02-04 | — | — | US | disclosed |
| WO-2020023872-A1 | USE OF TOLL-LIKE RECEPTOR 2 (TLR-2) AGONIST FOR MODULATING HUMAN IMMUNE RESPONSE | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2020-01-30 | — | — | WO | disclosed |
| US-20200031843-A1 | CHROMIUM-MEDIATED COUPLING AND APPLICATION TO THE SYNTHESIS OF HALICHONDRINS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2020-01-30 | — | — | US | disclosed |
| US-20200031861-A1 | BICONJUGATABLE LABELS AND METHODS OF USE | Quantum-Si Incorporated (US) | 2020-01-30 | — | — | US | disclosed |
| US-10544151-B2 | Compounds and uses thereof | KALA PHARMACEUTICALS, INC. (US) | 2020-01-28 | — | — | US | disclosed |
| US-10544182-B2 | Synthesis of desosamines | Presidents and Fellow of Harvard College (US) | 2020-01-28 | — | — | US | disclosed |
| US-10544149-B2 | Bicyclic alkyne derivatives and uses thereof | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2020-01-28 | — | — | US | disclosed |
| US-10538535-B2 | Antitumoral compounds | PHARMA MAR, S.A. (ES) | 2020-01-21 | — | — | US | disclosed |
| EP-2874994-B1 | 3,5,N-TRIHYDROXY-ALKANAMIDE AND DERIVATIVES: METHOD FOR MAKING SAME AND USE THEREOF | ACADEMIA SINICA (TW) | 2020-01-08 | — | — | EP | disclosed |
| WO-2019200367-A9 | BRUSH PRODRUGS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2019-12-19 | — | — | WO | disclosed |
| US-10508121-B2 | Cortistatin analogues and syntheses and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2019-12-17 | — | — | US | disclosed |
| US-10500293-B2 | Compositions, methods, and systems for the synthesis and use of imaging agents | LANTHEUS MEDICAL IMAGING, INC. (US) | 2019-12-10 | — | — | US | disclosed |
| US-20190367487-A1 | IMIDAZOLYL KINASE INHIBITORS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2019-12-05 | — | — | US | disclosed |
| CN-110520117-A | Substituted eutectic of glycine compound and application thereof | SYNEURX INT TAIWAN CORP | 2019-11-29 | — | — | CN | disclosed |
| US-20190350931-A1 | COMBINATION THERAPY | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2019-11-21 | — | — | US | disclosed |
| EP-3569598-A1 | INHIBITORS OF C-JUN-N-TERMINAL KINASE (JNK) | Dana Farber Cancer Institute, Inc. (US) | 2019-11-20 | — | — | EP | disclosed |
| EP-2983659-B1 | DRUG DELIVERY POLYMER AND USES THEREOF | MASSACHUSETTS INST TECHNOLOGY (US) | 2019-11-20 | — | — | EP | disclosed |
| US-10478507-B2 | Peptide-based multiple-drug delivery vehicle | ARIEL-UNIVERSITY RESEARCH AND DEVELOPMENT COMPANY LTD. (IL) | 2019-11-19 | — | — | US | disclosed |
| US-10479995-B2 | Oligonucleotide compositions and methods thereof | WAVE LIFE SCIENCES LTD. (SG) | 2019-11-19 | — | — | US | disclosed |
| US-20190345116-A1 | SYNTHESIS OF TETRACYCLINES AND ANALOGUES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2019-11-14 | — | — | US | disclosed |
| US-20190343842-A1 | USES OF SALT-INDUCIBLE KINASE (SIK) INHIBITORS | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2019-11-14 | — | — | US | disclosed |
| US-20190343958-A1 | CONJUGATES OF KINASE INHIBITORS AND CYANINE DYES | UNITED STATES GOVERNMENT | 2019-11-14 | — | — | US | disclosed |
| US-20190343617-A1 | VALVE INSERTABLE INTO A BODY LUMEN | COLOPLAST A/S (DK) | 2019-11-14 | — | — | US | disclosed |
| US-20190345188-A1 | NOVEL BICYCLIC NUCLEOSIDES AND OLIGOMERS PREPARED THEREFROM | Universität Bern (CH) | 2019-11-14 | — | — | US | disclosed |
| US-20190343826-A1 | TETRAHYDRO- AND DIHYDRO-ISOQUINOLINE PRMT5 INHIBITORS AND USES THEREOF | Epizyme, Inc. | 2019-11-14 | — | — | US | disclosed |
| US-20190343803-A1 | COMBINATION THERAPY | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2019-11-14 | — | — | US | disclosed |
| WO-2019215333-A1 | OLIGONUCLEOTIDES CONJUGATES COMPRISING 7'-5'-ALPHA-ANOMERIC-BICYCLIC SUGAR NUCLEOSIDES | ALPHA ANOMERIC SAS (FR) | 2019-11-14 | — | — | WO | disclosed |
| WO-2018227012-A9 | POLYMER-LIPID MATERIALS FOR DELIVERY OF NUCLEIC ACIDS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2019-11-14 | — | — | WO | disclosed |
| EP-3565604-A1 | METHODS FOR ASSEMBLING SCAVENGING PARTICLES | Nanotics, LLC (US) | 2019-11-13 | — | — | EP | disclosed |
| EP-3567029-A1 | COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS | Lantheus Medical Imaging, Inc. (US) | 2019-11-13 | — | — | EP | disclosed |
| EP-2616513-B1 | CATALYSTS AND METHODS FOR POLYMER SYNTHESIS | SAUDI ARAMCO TECH CO (SA) | 2019-11-06 | — | — | EP | disclosed |
| US-10464949-B2 | Thiazolyl-containing compounds for treating proliferative diseases | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2019-11-05 | — | — | US | disclosed |
| EP-3560503-A1 | RNA INTERFERENCE IN DERMAL AND FIBROTIC INDICATIONS | Phio Pharmaceuticals Corp. (US) | 2019-10-30 | — | — | EP | disclosed |
| US-10457691-B2 | Macrocyclic kinase inhibitors and uses thereof | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2019-10-29 | — | — | US | disclosed |
| EP-2790697-B1 | USES OF 4'-DESFERRITHIOCIN ANALOGS | UNIV FLORIDA (US) | 2019-10-23 | — | — | EP | disclosed |
| US-10450281-B1 | Compounds and methods for treating cancer | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2019-10-22 | — | — | US | disclosed |
| US-10450568-B2 | Oligonucleotide compositions and methods thereof | WAVE LIFE SCIENCES LTD. (SG) | 2019-10-22 | — | — | US | disclosed |
| US-20190315747-A9 | INHIBITORS OF CYCLIN-DEPENDENT KINASES | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2019-10-17 | — | — | US | disclosed |
| WO-2019168654-A9 | DNA-TEMPLATED MACROCYCLE LIBRARY | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2019-10-17 | — | — | WO | disclosed |
| WO-2019200367-A1 | BRUSH PRODRUGS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2019-10-17 | — | — | WO | disclosed |
| US-20190315752-A1 | BICYCLIC UREA KINASE INHIBITORS AND USES THEREOF | THE BROAD INSTITUTE, INC. (US) | 2019-10-17 | — | — | US | disclosed |
| US-20190315755-A1 | BICYCLIC HETEROCYCLIC DERIVATIVES AS MNK1 AND MNK2 MODULATORS AND USES THEREOF | AGENCY SCIENCE TECH & RES (SG) | 2019-10-17 | — | — | US | disclosed |
| US-20190315918-A1 | FUNCTIONALIZED POLYMERS | FISH & RICHARDSON PC | 2019-10-17 | — | — | US | disclosed |
| WO-2019199628-A1 | AZIDE INSULIN ANALOGUES | MERCK SHARP & DOHME CORP. (US) | 2019-10-17 | — | — | WO | disclosed |
| EP-2968274-B1 | MEROPENEM DERIVATIVES AND USES THEREOF | KALA PHARMACEUTICALS INC (US) | 2019-10-16 | — | — | EP | disclosed |
| US-10442820-B2 | — | — | 2019-10-15 | — | — | US | disclosed |
| WO-2019195682-A1 | ARYL HYDROCARBON RECEPTOR MODULATORS AND USES THEREOF | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. (US) | 2019-10-10 | — | — | WO | disclosed |
| EP-2882719-B1 | PYRIDAZIN-3(2H)-ONE DERIVATIVES AS IMAGING AGENTS FOR DETECTING MYOCARDIAL PERFUSION | LANTHEUS MEDICAL IMAGING INC (US) | 2019-10-09 | — | — | EP | disclosed |
| EP-3548069-A1 | COMBINATION THERAPY | GlaxoSmithKline Intellectual Property Development Limited (GB) | 2019-10-09 | — | — | EP | disclosed |
| EP-3548068-A1 | COMBINATION THERAPY | GlaxoSmithKline Intellectual Property Development Limited (GB) | 2019-10-09 | — | — | EP | disclosed |
| EP-3548020-A1 | COMBINATION THERAPY | GlaxoSmithKline Intellectual Property Development Limited (GB) | 2019-10-09 | — | — | EP | disclosed |
| EP-3548096-A1 | INHIBITOR-FUNCTIONALIZED ULTRASMALL NANOPARTICLES AND METHODS THEREOF | Memorial Sloan Kettering Cancer Center (US) | 2019-10-09 | — | — | EP | disclosed |
| EP-3548638-A1 | METHODS OF TREATING CANCER | GlaxoSmithKline Intellectual Property Development Limited (GB) | 2019-10-09 | — | — | EP | disclosed |
| EP-3548502-A1 | NOVEL BICYCLIC NUCLEOSIDES AND OLIGOMERS PREPARED THEREFROM | Universität Bern (CH) | 2019-10-09 | — | — | EP | disclosed |
| US-10435431-B2 | 3,3 disubstituted 19-nor pregnane compounds, compositions, and uses thereof | SAGE THERAPEUTICS, INC. (US) | 2019-10-08 | — | — | US | disclosed |
| US-20190300576-A1 | SOLUTION-PHASE AFFINITY SELECTION OF INHIBITORS FROM COMBINATORIAL PEPTIDE LIBRARIES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2019-10-03 | — | — | US | disclosed |
| EP-2569019-B1 | COMPOSITIONS, METHODS AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS | LANTHEUS MEDICAL IMAGING INC (US) | 2019-10-02 | — | — | EP | disclosed |
| EP-3544970-A1 | INHIBITORS OF INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASES AND USES THEREOF | Dana-Farber Cancer Institute, Inc. (US) | 2019-10-02 | — | — | EP | disclosed |
| EP-3544971-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASE 12 (CDK12) AND USES THEREOF | Dana-Farber Cancer Institute, Inc. (US) | 2019-10-02 | — | — | EP | disclosed |
| WO-2019182942-A1 | TYROSINE-SPECIFIC FUNCTIONALIZED INSULIN AND INSULIN ANALOGS | MERCK SHARP & DOHME CORP. (US) | 2019-09-26 | — | — | WO | disclosed |
| US-20190292178-A9 | HOST TARGETED INHIBITORS OF DENGUE VIRUS AND OTHER VIRUSES | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2019-09-26 | — | — | US | disclosed |
| US-20190292527-A1 | HIGHLY ACTIVE SELF-SUFFICIENT NITRATION BIOCATALYSTS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2019-09-26 | — | — | US | disclosed |
| US-20190284172-A1 | Urea Derivatives and Uses Thereof | KALA BIO, Inc. | 2019-09-19 | — | — | US | disclosed |
| US-20190282712-A1 | INHIBITOR-FUNCTIONALIZED ULTRASMALL NANOPARTICLES AND METHODS THEREOF | MEMORIAL SLOAN KETTERING CANCER CENTER | 2019-09-19 | — | — | US | disclosed |
| EP-2451776-B1 | N-ALKOXYAMIDE CONJUGATES AS IMAGING AGENTS | LANTHEUS MEDICAL IMAGING INC (US) | 2019-09-18 | — | — | EP | disclosed |
| CN-110248676-A | Combination treatment | 葛兰素史密斯克莱知识产权发展有限公司 | 2019-09-17 | — | — | CN | disclosed |
| CN-110234342-A | Combination treatment | 葛兰素史密斯克莱知识产权发展有限公司 | 2019-09-13 | — | — | CN | disclosed |
| US-20190276426-A1 | INHIBITORS OF INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASES AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2019-09-12 | — | — | US | disclosed |
| EP-3536323-A1 | USES OF SALT-INDUCIBLE KINASE (SIK) INHIBITORS | Dana Farber Cancer Institute, Inc. (US) | 2019-09-11 | — | — | EP | disclosed |
| EP-3536695-A1 | FUNCTIONALIZED POLYMERS | QuiaPEG Pharmaceuticals AB (SE) | 2019-09-11 | — | — | EP | disclosed |
| EP-3535254-A1 | COMPOUNDS FOR MALT1 DEGRADATION | Cornell University Cornell Center For Technology, Enterprise & Commercialization ("CCTEC") (US) | 2019-09-11 | — | — | EP | disclosed |
| US-10406237-B2 | Amine-containing transfection reagents and methods for making and using same | LIFE TECHNOLOLGIES CORPORATION (US) | 2019-09-10 | — | — | US | disclosed |
| CN-110225983-A | Methods of treating cancer | 葛兰素史密斯克莱知识产权发展有限公司 | 2019-09-10 | — | — | CN | disclosed |
| CN-110214010-A | Combination treatment | 葛兰素史密斯克莱知识产权发展有限公司 | 2019-09-06 | — | — | CN | disclosed |
| US-20190271015-A1 | ENZYMATIC SYNTHESIS OF KAVALACTONES AND FLAVOKAVAINS | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 2019-09-05 | — | — | US | disclosed |
| EP-3532492-A1 | HIGHLY ACTIVE SELF-SUFFICIENT NITRATION BIOCATALYSTS | University of Florida Research Foundation, Incorporated (US) | 2019-09-04 | — | — | EP | disclosed |
| EP-3024327-B1 | INHIBITORS OF TRANSCRIPTION FACTORS AND USES THEREOF | DANA FARBER CANCER INST INC (US) | 2019-09-04 | — | — | EP | disclosed |
| US-10398703-B2 | Therapeutic compounds and uses thereof | KALA PHARMACEUTICALS, INC. (US) | 2019-09-03 | — | — | US | disclosed |
| US-10398781-B2 | Conjugate based systems for controlled drug delivery | SMARTCELLS, INC. (US) | 2019-09-03 | — | — | US | disclosed |
| CN-105793262-B | Two cycloalkyne derivatives and application thereof | 新加坡科技研究局 | 2019-09-03 | — | — | CN | disclosed |
| CN-110183461-A | Cortex chalone analog and its synthesis and purposes | 哈佛学院院长等 | 2019-08-30 | — | — | CN | disclosed |
| US-20190262299-A1 | CO-CRYSTALS OF SUBSTITUTED GLYCINE AND USES THEREOF | SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) | 2019-08-29 | — | — | US | disclosed |
| WO-2019165216-A1 | SMALL MOLECULES THAT BLOCK PROTEASOME-ASSOCIATED UBIQUITIN RECEPTOR RPN13 FUNCTION AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2019-08-29 | — | — | WO | disclosed |
| WO-2019165229-A1 | SMALL MOLECULES FOR INDUCING SELECTIVE PROTEIN DEGRADATION AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2019-08-29 | — | — | WO | disclosed |
| US-20190263785-A1 | COMPOUNDS FOR MALT1 DEGRADATION | CORNELL UNIVERSITY (US) | 2019-08-29 | — | — | US | disclosed |
| EP-2935247-B1 | PRMT5 INHIBITORS AND USES THEREOF | EPIZYME INC (US) | 2019-08-28 | — | — | EP | disclosed |
| US-10392388-B2 | Meropenem derivatives and uses thereof | KALA PHARMACEUTICALS, INC. (US) | 2019-08-27 | — | — | US | disclosed |
| US-10392400-B2 | Palladium-mediated ketolization | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2019-08-27 | — | — | US | disclosed |
| US-10391089-B2 | PRMT5 inhibitors and uses therof | Epizyme, Inc. (US) | 2019-08-27 | — | — | US | disclosed |
| CN-110167601-A | Inhibitor-small nanoparticle of functionalization ultra micro and its method | 纪念斯隆凯特琳癌症中心 | 2019-08-23 | — | — | CN | disclosed |
| US-20190256490-A1 | ANALOGS OF YOHIMBINE AND USES THEREOF | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2019-08-22 | — | — | US | disclosed |
| US-10383946-B2 | Conjugates of biologically active molecules to functionalized polymers | QUIAPEG PHARMACEUTICALS AB (SE) | 2019-08-20 | — | — | US | disclosed |
| US-20190249173-A1 | METHODS AND COMPOSITIONS OF BIOLOGICALLY ACTIVE AGENTS | WAVE LIFE SCIENCES LTD. (SG) | 2019-08-15 | — | — | US | disclosed |
| US-20190248778-A1 | INHIBITORS OF C-JUN-N-TERMINAL KINASE (JNK) | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2019-08-15 | — | — | US | disclosed |
| EP-3523437-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | Wave Life Sciences Ltd. (SG) | 2019-08-14 | — | — | EP | disclosed |
| EP-3524272-A1 | ENHANCED ANTI-INFLUENZA AGENTS CONJUGATED WITH ANTI-INFLAMMATORY ACTIVITY | Academia Sinica (TW) | 2019-08-14 | — | — | EP | disclosed |
| WO-2019149959-A1 | GHRELIN O-ACYLTRANSFERASE INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2019-08-08 | — | — | WO | disclosed |
| WO-2019152802-A1 | CATIONIC POLYMERS | TRANSLATE BIO, INC. (US) | 2019-08-08 | — | — | WO | disclosed |
| US-20190240349-A1 | ALKENYL SUBSTITUTED 2,5-PIPERAZINEDIONES, COMPOSITIONS, AND USES THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2019-08-08 | — | — | US | disclosed |
| US-20190241526-A1 | HSP70 MODULATORS AND METHODS FOR MAKING AND USING THE SAME | MEMORIAL SLOAN KETTERING CANCER CENTER | 2019-08-08 | — | — | US | disclosed |
| EP-2858678-B1 | CONJUGATES OF BIOLOGICALLY ACTIVE MOLECULES TO FUNCTIONALIZED POLYMERS | QUIAPEG PHARMACEUTICALS AB (SE) | 2019-08-07 | — | — | EP | disclosed |
| US-20190233826-A1 | RNA INTERFERENCE IN OCULAR INDICATIONS | PHIO PHARMACEUTICALS CORP. (US) | 2019-08-01 | — | — | US | disclosed |
| US-20190233586-A1 | POLYCARBONATE POLYOL COMPOSITIONS AND METHODS | NOVOMER, INC. | 2019-08-01 | — | — | US | disclosed |
| WO-2019148036-A1 | COMPOUNDS FOR THE TREATMENT OF KINASE-DEPENDENT DISORDERS | EXELIXIS, INC. (US) | 2019-08-01 | — | — | WO | disclosed |
| WO-2019148044-A1 | COMPOUNDS FOR THE TREATMENT OF KINASE-DEPENDENT DISORDERS | EXELIXIS, INC. (US) | 2019-08-01 | — | — | WO | disclosed |
| WO-2019148043-A1 | COMPOUNDS FOR THE TREATMENT OF KINASE-DEPENDENT DISORDERS | EXELIXIS, INC. (US) | 2019-08-01 | — | — | WO | disclosed |
| EP-3148552-B1 | BIODEGRADABLE LIPIDS FOR DELIVERY OF NUCLEIC ACIDS | TRANSLATE BIO INC (US) | 2019-07-31 | — | — | EP | disclosed |
| WO-2019142135-A1 | TRICYCLO-DNA NUCLEOSIDE PRECURSORS AND PROCESSES FOR PREPARING THE SAME | SYNTHENA AG (CH) | 2019-07-25 | — | — | WO | disclosed |
| US-20190224326-A1 | NUCLEIC ACID CONJUGATES AND USES THEREOF | TRANSLATE BIO MA, INC. (US) | 2019-07-25 | — | — | US | disclosed |
| EP-2391714-B2 | METHODS FOR LIGATION AND USES THEREOF | WHITEHEAD INST BIOMEDICAL RES (US) | 2019-07-24 | — | — | EP | disclosed |
| CN-110042099-A | RNA in skin and fibrotic conditions is interfered | 菲奥医药公司 | 2019-07-23 | — | — | CN | disclosed |
| US-20190216812-A1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | KALA BIO, Inc. | 2019-07-18 | — | — | US | disclosed |
| US-20190218194-A1 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | Epizyme, Inc. | 2019-07-18 | — | — | US | disclosed |
| US-20190216754-A1 | COMBINATION OF A SELECTIVE HISTONE DEACETYLASE 3 (HDAC3) INHIBITOR AND AN IMMUNOTHERAPY AGENT FOR THE TREATMENT OF CANCER | KDAC THERAPEUTICS INC (US) | 2019-07-18 | — | — | US | disclosed |
| US-20190216895-A1 | BOLAAMPHIPHILIC COMPOUNDS, COMPOSITIONS AND USES THEREOF | LAUREN SCIENCES LLC (US) | 2019-07-18 | — | — | US | disclosed |
| CN-110023322-A | New bicyclic nucleoside and oligomer prepared therefrom | 伯尔尼大学 | 2019-07-16 | — | — | CN | disclosed |
| US-10351570-B2 | Compounds and uses thereof | KALA PHARMACEUTICALS, INC. (US) | 2019-07-16 | — | — | US | disclosed |
| US-20190211020-A1 | BICYCLIC HETEROARYL DERIVATIVES AS MNK1 AND MNK2 MODULATORS AND USES THEREOF | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2019-07-11 | — | — | US | disclosed |
| US-20190211000-A1 | ACTIVATORS OF CLASS I HISTONE DEACETYLASES (HDACS) AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2019-07-11 | — | — | US | disclosed |
| US-20190209604-A1 | OLIGONUCLEOTIDES, COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2019-07-11 | — | — | US | disclosed |
| US-10342798-B2 | Fused bicyclic pyrimidine derivatives and uses thereof | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2019-07-09 | — | — | US | disclosed |
| US-10344038-B2 | Chromium-mediated coupling and application to the synthesis of halichondrins | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2019-07-09 | — | — | US | disclosed |
| CN-109983128-A | Oligonucleotide composition and its method | 波涛生命科学有限公司 | 2019-07-05 | — | — | CN | disclosed |
| US-20190202800-A1 | SMALL MOLECULE MODULATORS OF THE ANDROGEN RECEPTOR | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2019-07-04 | — | — | US | disclosed |
| US-20190202862-A1 | STAPLED AND STITCHED POLYPEPTIDES AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2019-07-04 | — | — | US | disclosed |
| US-10336724-B2 | D-amino acid oxidase inhibitors and therapeutic uses thereof | SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) | 2019-07-02 | — | — | US | disclosed |
| US-10336784-B2 | Methods for modular synthesis of N-glycans and arrays thereof | ACADEMIA SINICA (TW) | 2019-07-02 | — | — | US | disclosed |
| US-10335418-B2 | Methods and compositions for treating metabolic syndrome | TOPOKINE THERAPEUTICS, INC. (US) | 2019-07-02 | — | — | US | disclosed |
| US-20190192532-A1 | COMBINATION THERAPY OF BROMODOMAIN INHIBITORS AND CHECKPOINT BLOCKADE | PETER MACCALLUM CANCER INSTITUTE (AU) | 2019-06-27 | — | — | US | disclosed |
| US-20190194390-A1 | AMINO-POLYESTERS FOR DRUG DELIVERY | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2019-06-27 | — | — | US | disclosed |
| US-20190194444-A1 | GENE DELIVERY CARRIER | POLITECNICO DI MILANO (IT) | 2019-06-27 | — | — | US | disclosed |
| US-20190193062-A1 | CATALYSTS FOR POLYCARBONATE PRODUCTION | ARAMCO PERFORMANCE MATERIALS LLC | 2019-06-27 | — | — | US | disclosed |
| US-20190192672-A1 | DRUG DELIVERY POLYMER AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2019-06-27 | — | — | US | disclosed |
| EP-2922575-B1 | TRIOXACARCINS, TRIOXACARCIN-ANTIBODY CONJUGATES, AND USES THEREOF | HARVARD COLLEGE (US) | 2019-06-26 | — | — | EP | disclosed |
| US-10328041-B2 | Co-crystals of substituted glycine and uses thereof | SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) | 2019-06-25 | — | — | US | disclosed |
| US-10328042-B2 | Co-crystals of substituted glycine and uses thereof | SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) | 2019-06-25 | — | — | US | disclosed |
| US-10329280-B2 | Urea derivatives and uses thereof | KALA PHARMACEUTICALS, INC. (US) | 2019-06-25 | — | — | US | disclosed |
| WO-2019118583-A1 | HALOGENATED DERIVATIVES OF MORPHINANS AND USES THEREOF | XALUD THERAPEUTICS, INC. (US) | 2019-06-20 | — | — | WO | disclosed |
| US-20190185484-A1 | CORTISTATIN ANALOGUES AND SYNTHESES AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2019-06-20 | — | — | US | disclosed |
| EP-3498701-A1 | PRMT5 INHIBITORS AND USES THEREOF | Epizyme Inc (US) | 2019-06-19 | — | — | EP | disclosed |
| US-10321983-B2 | Valve | COLOPLAST A/S (DK) | 2019-06-18 | — | — | US | disclosed |
| US-20190177289-A1 | AMINOALCOHOL LIPIDOIDS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2019-06-13 | — | — | US | disclosed |
| US-20190177261-A1 | CO-CRYSTALS OF LITHIUM BENZOATE AND USES THEREOF | SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) | 2019-06-13 | — | — | US | disclosed |
| US-20190175584-A1 | KINASE INHIBITORS AND METHODS OF USE THEREOF | BROAD INST INC (US) | 2019-06-13 | — | — | US | disclosed |
| US-10314802-B2 | Isoprenyl compounds and methods thereof | SIGNUM BIOSCIENCES, INC. (US) | 2019-06-11 | — | — | US | disclosed |
| US-10316022-B2 | Urea derivatives and uses thereof | KALA PHARMACEUTICALS, INC. (US) | 2019-06-11 | — | — | US | disclosed |
| US-20190169110-A1 | CO-CRYSTALS OF SODIUM BENZOATE AND USES THEREOF | SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) | 2019-06-06 | — | — | US | disclosed |
| US-20190167795-A1 | CONJUGATED LIPOMERS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2019-06-06 | — | — | US | disclosed |
| EP-3013365-B1 | RM2 ANTIGENS AND USE THEREOF | ACADEMIA SINICA (TW) | 2019-06-05 | — | — | EP | disclosed |
| US-10308653-B2 | Diazepane derivatives and uses thereof | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2019-06-04 | — | — | US | disclosed |
| US-10307413-B2 | Tetrahydro- and dihydro-isoquinoline PRMT5 inhibitors and uses thereof | Epizyme, Inc. (US) | 2019-06-04 | — | — | US | disclosed |
| US-10309973-B2 | Surrogates of post-translationally modified proteins and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2019-06-04 | — | — | US | disclosed |
| US-10308761-B2 | Methods for polymer synthesis | SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) | 2019-06-04 | — | — | US | disclosed |
| CN-104350055-B | Bicyclic heteroaryl derivatives and application thereof as MNK1 and MNK2 regulator | 新加坡科技研究局 | 2019-05-31 | — | — | CN | disclosed |
| US-10301426-B2 | Polycarbonate polyol compositions and methods | SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) | 2019-05-28 | — | — | US | disclosed |
| US-10301351-B2 | Stitched polypeptides | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2019-05-28 | — | — | US | disclosed |
| US-20190153168-A1 | BIOMATERIAL | VYSERA BIOMEDICAL LIMITED (IE) | 2019-05-23 | — | — | US | disclosed |
| EP-3486269-A1 | POLYMERIZATION SYSTEM FOR THE COPOLYMERIZATION OF CO2 AND EPOXIDES AND RELATED METHOD | SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) | 2019-05-22 | — | — | EP | disclosed |
| EP-2550001-B1 | RNA INTERFERENCE IN OCULAR INDICATIONS | PHIO PHARM CORP (US) | 2019-05-22 | — | — | EP | disclosed |
| US-10293057-B2 | Biodegradable lipids for delivery of nucleic acids | TRANSLATE BIO, INC. (US) | 2019-05-21 | — | — | US | disclosed |
| CN-106103452-B | Cortictatin analogs, their synthesis and use | 哈佛学院院长等 | 2019-05-21 | — | — | CN | disclosed |
| US-20190144466-A1 | MAX BINDERS AS MYC MODULATORS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2019-05-16 | — | — | US | disclosed |
| EP-3481430-A1 | NUCLEIC ACID CONJUGATES AND USES THEREOF | TRANSLATE BIO MA, INC. (US) | 2019-05-15 | — | — | EP | disclosed |
| EP-3483150-A1 | ACTIVATORS OF CLASS 1 HISTONE DEACETYLASES (HDACS) AND USES THEREOF | Massachusetts Institute Of Technology (US) | 2019-05-15 | — | — | EP | disclosed |
| EP-3481830-A1 | BICYCLIC UREA KINASE INHIBITORS AND USES THEREOF | The Broad Institute, Inc. (US) | 2019-05-15 | — | — | EP | disclosed |
| EP-3003314-B1 | HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF CANCER | KALA PHARMACEUTICALS INC (US) | 2019-05-15 | — | — | EP | disclosed |
| EP-2822935-B1 | INHIBITORS OF C-JUN-N-TERMINAL KINASE (JNK) | DANA FARBER CANCER INST INC (US) | 2019-05-15 | — | — | EP | disclosed |
| US-10286082-B2 | Biodegradable lipids for delivery of nucleic acids | TRANSLATE BIO, INC. (US) | 2019-05-14 | — | — | US | disclosed |
| US-10285991-B2 | Therapeutic compounds and uses thereof | KALA PHARMACEUTICALS, INC. (US) | 2019-05-14 | — | — | US | disclosed |
| US-10286083-B2 | Biodegradable lipids for delivery of nucleic acids | TRANSLATE BIO, INC. (US) | 2019-05-14 | — | — | US | disclosed |
| US-10287268-B2 | Imidazolyl kinase inhibitors and uses thereof | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2019-05-14 | — | — | US | disclosed |
| CN-109734893-A | Catalyst And Method for synthetic polymer | 沙特阿美技术公司 | 2019-05-10 | — | — | CN | disclosed |
| CN-109734894-A | Catalyst And Method for synthetic polymer | 沙特阿美技术公司 | 2019-05-10 | — | — | CN | disclosed |
| US-20190135796-A1 | EZH2 INHIBITORS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2019-05-09 | — | — | US | disclosed |
| US-20190135819-A1 | CARM1 INHIBITORS AND USES THEREOF | Epizyme, Inc. | 2019-05-09 | — | — | US | disclosed |
| US-20190135868-A1 | SYNTHETIC DNA BINDING DOMAIN PEPTIDES AND USES THEREOF | THE UNIVERSITY OF CHICAGO | 2019-05-09 | — | — | US | disclosed |
| US-20190135849-A1 | STEREOSELECTIVE SYNTHESIS OF PHOSPHOROTHIOATE OLIGORIBONUCLEOTIDES | ETH ZURICH (CH) | 2019-05-09 | — | — | US | disclosed |
| US-20190135790-A1 | DIAMINOPYRIMIDINE BENZENESULFONE DERIVATIVES AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2019-05-09 | — | — | US | disclosed |
| EP-2550002-B1 | RNA INTERFERENCE IN DERMAL AND FIBROTIC INDICATIONS | PHIO PHARM CORP (US) | 2019-05-08 | — | — | EP | disclosed |
| US-10280168-B2 | Bicyclic heteroaryl derivatives as MNK1 and MNK2 modulators and uses thereof | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2019-05-07 | — | — | US | disclosed |
| US-20190127733-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2019-05-02 | — | — | US | disclosed |
| US-20190125887-A1 | CONJUGATES OF BIOLOGICALLY ACTIVE MOLECULES TO FUNCTIONALIZED POLYMERS | QUIAPEG AB (SE) | 2019-05-02 | — | — | US | disclosed |
| US-10273240-B2 | Cortistatin analogues, syntheses, and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2019-04-30 | — | — | US | disclosed |
| US-10273264-B2 | Cortistatin analogues and syntheses and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2019-04-30 | — | — | US | disclosed |
| US-10273241-B2 | Cortistatin analogues and syntheses and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2019-04-30 | — | — | US | disclosed |
| WO-2019079662-A1 | BIO-INSPIRED POLYMERS FOR USE AS SYNTHETIC MUCINS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2019-04-25 | — | — | WO | disclosed |
| WO-2019079706-A1 | AMINOGLYCOSIDE ANTIBIOTICS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2019-04-25 | — | — | WO | disclosed |
| US-20190119208-A1 | ARTIFICIAL SELF-SUFFICIENT CYTOCHROME P450S | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2019-04-25 | — | — | US | disclosed |
| US-20190117682-A1 | BIO-INSPIRED POLYMERS FOR USE AS SYNTHETIC MUCINS | MASSACHUSETTS INST TECHNOLOGY (US) | 2019-04-25 | — | — | US | disclosed |
| US-20190119286-A1 | DIAZENE DIRECTED MODULAR SYNTHESIS OF COMPOUNDS WITH QUATERNARY CARBON CENTERS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2019-04-25 | — | — | US | disclosed |
| US-20190117798-A1 | COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS | MODERNATX, INC. (US) | 2019-04-25 | — | — | US | disclosed |
| US-20190119301-A1 | THIAZOLYL-CONTAINING COMPOUNDS FOR TREATING PROLIFERATIVE DISEASES | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2019-04-25 | — | — | US | disclosed |
| EP-3471723-A1 | HEDGEHOG ACYLTRANSFERASE INHIBITORS AND USES THEREOF | Memorial Sloan Kettering Cancer Center (US) | 2019-04-24 | — | — | EP | disclosed |
| EP-2766380-B1 | 3,3 DISUBSTITUTED 19-NOR PREGNANE COMPOUNDS, COMPOSITIONS, AND USES THEREOF | SAGE THERAPEUTICS INC (US) | 2019-04-24 | — | — | EP | disclosed |
| US-10265321-B2 | Uses of salt-inducible kinase (SIK) inhibitors | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2019-04-23 | — | — | US | disclosed |
| US-20190112289-A1 | D-AMINO ACID OXIDASE INHIBITORS AND THERAPEUTIC USES THEREOF | TSAI, GUOCHUAN EMIL (US) | 2019-04-18 | — | — | US | disclosed |
| US-20190112305-A1 | BONE MARROW ON X CHROMOSOME KINASE (BMX) INHIBITORS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2019-04-18 | — | — | US | disclosed |
| EP-3470395-A1 | AMINE-CONTAINING TRANSFECTION REAGENTS AND METHODS FOR MAKING AND USING SAME | Life Technologies Corporation (US) | 2019-04-17 | — | — | EP | disclosed |
| CN-105287472-B | Antibacterial agent is used to treat the purposes of epithelial-related disease condition | 西格纳姆生物科学公司 | 2019-04-12 | — | — | CN | disclosed |
| US-20190106696-A1 | CHIRAL DESIGN | WAVE LIFE SCIENCES LTD. (SG) | 2019-04-11 | — | — | US | disclosed |
| EP-3466942-A1 | PROCESSES FOR THE PREPARATION OF (S)-3-4-((4-(MORPHOLINOMETHYL) BENZYL)OXY)-1-OXOISOINDOLIN-2-YL) PIPERIDINE-2,6-DIONE AND PHARMACEUTICALLY ACCEPTABLE FORMS THEREOF | Celgene Corporation (US) | 2019-04-10 | — | — | EP | disclosed |
| EP-3463386-A1 | OLIGONUCLEOTIDES, COMPOSITIONS AND METHODS THEREOF | Wave Life Sciences Ltd. (SG) | 2019-04-10 | — | — | EP | disclosed |
| US-20190100511-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 (CDK7) | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2019-04-04 | — | — | US | disclosed |
| US-20190100496-A1 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | Epizyme, Inc. | 2019-04-04 | — | — | US | disclosed |
| US-20190099748-A1 | DIRECT PALLADIUM-CATALYZED AROMATIC FLUORINATION | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2019-04-04 | — | — | US | disclosed |
| US-20190099486-A1 | HUMAN iNKT CELL ACTIVATION USING GLYCOLIPIDS WITH ALTERED GLYCOSYL GROUPS | ACADEMIA SINICA (TW) | 2019-04-04 | — | — | US | disclosed |
| WO-2019067587-A1 | USE OF METFORMIN AND ANALOGS THEREOF TO REDUCE RAN PROTEIN LEVELS IN THE TREATMENT OF NEUROLOGICAL DISORDERS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2019-04-04 | — | — | WO | disclosed |
| EP-2917203-B1 | METHOD FOR IDENTIFYING MYC INHIBITORS | DANA FARBER CANCER INST INC (US) | 2019-04-03 | — | — | EP | disclosed |
| CN-109563509-A | Target the delivering nucleic acid compound certainly of the reduction size of long non-coding RNA | 阿克赛医药公司 | 2019-04-02 | — | — | CN | disclosed |
| CN-109563018-A | Eutectic of sodium benzoate and application thereof | 心悦生医股份有限公司 | 2019-04-02 | — | — | CN | disclosed |
| CN-109562122-A | Oligonucleotides, composition and its method | 波涛生命科学有限公司 | 2019-04-02 | — | — | CN | disclosed |
| CN-109563024-A | Eutectic of lithium benzoate and use thereof | 心悦生医股份有限公司 | 2019-04-02 | — | — | CN | disclosed |
| US-20190092737-A1 | 2-THIOXOTHIAZOLIDIN-4-ONE DERIVATIVES ACTIVE AS TRANSTHYRETIN LIGANDS AND USES THEREOF | BSIM2 - Biomolecular Simulations Lda. (PT) | 2019-03-28 | — | — | US | disclosed |
| EP-3458464-A1 | STEREOSELECTIVE SYNTHESIS OF PHOSPHOROTHIOATE OLIGORIBONUCLEOTIDES | ETH Zurich (CH) | 2019-03-27 | — | — | EP | disclosed |
| EP-3075248-B1 | USE OF ANTI-BACTERIAL AGENTS FOR THE TREATMENT OF EPITHELIAL-RELATED CONDITIONS | SIGNUM BIOSCIENCES INC (US) | 2019-03-27 | — | — | EP | disclosed |
| EP-2753605-B1 | COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS | LANTHEUS MEDICAL IMAGING INC (US) | 2019-03-27 | — | — | EP | disclosed |
| US-10240149-B2 | Reduced size self-delivering RNAi compounds | PHIO PHARMACEUTICALS CORP. (US) | 2019-03-26 | — | — | US | disclosed |
| US-20190083570-A1 | PEPTIDES WITH ANTI-CANCER ACTIVITY | IDP DISCOVERY PHARMA, S.L. (ES) | 2019-03-21 | — | — | US | disclosed |
| US-20190083482-A1 | PRMT5 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2019-03-21 | — | — | US | disclosed |
| US-20190084924-A1 | PROCESSES FOR THE PREPARATION OF (S)-TERT-BUTYL 4,5-DIAMINO-5-OXOPENTANOATE | CELGENE CORPORATION | 2019-03-21 | — | — | US | disclosed |
| CN-109477108-A | Oligonucleotide composition and its method | 波涛生命科学有限公司 | 2019-03-15 | — | — | CN | disclosed |
| US-20190076533-A1 | BOLAAMPHIPHILIC COMPOUNDS, COMPOSITIONS AND USES THEREOF | LAUREN SCIENCES LLC (US) | 2019-03-14 | — | — | US | disclosed |
| US-20190076462-A1 | AMINO ACID-, PEPTIDE- AND POLYPEPTIDE-LIPIDS, ISOMERS, COMPOSITIONS, AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2019-03-14 | — | — | US | disclosed |
| EP-3452597-A1 | METHODS AND COMPOSITIONS OF BIOLOGICALLY ACTIVE AGENTS | Wave Life Sciences Ltd. (SG) | 2019-03-13 | — | — | EP | disclosed |
| EP-3452596-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | Wave Life Sciences Ltd. (SG) | 2019-03-13 | — | — | EP | disclosed |
| US-10227390-B2 | Stabilized polypeptide insulin receptor modulators | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2019-03-12 | — | — | US | disclosed |
| US-10227307-B2 | PRMT1 inhibitors and uses thereof | Epizyme, Inc. (US) | 2019-03-12 | — | — | US | disclosed |
| CN-109462995-A | The method and composition of bioactivator | 波涛生命科学有限公司 | 2019-03-12 | — | — | CN | disclosed |
| WO-2019046775-A1 | INHIBITORS OF EGFR AND/OR HER2 AND METHODS OF USE | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2019-03-07 | — | — | WO | disclosed |
| US-20190070295-A1 | Photoswitchable HDAC Inhibitors | THE GENERAL HOSPITAL CORPORATION | 2019-03-07 | — | — | US | disclosed |
| US-20190054187-A1 | DRUG DELIVERY POLYMERS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2019-02-21 | — | — | US | disclosed |
| CN-109362222-A | Selective estrogen receptor degradants and uses thereof | 益方生物科技（上海）有限公司 | 2019-02-19 | — | — | CN | disclosed |
| US-10207007-B2 | Conjugates of tumor necrosis factor inhibitors to functionalized polymers | QUIAPEG PHARMACEUTICALS AB (SE) | 2019-02-19 | — | — | US | disclosed |
| US-10207010-B2 | Compositions and methods for delivery of agents | MODERNATX, INC. (US) | 2019-02-19 | — | — | US | disclosed |
| CN-105131067-B | RNA in skin and fibrotic conditions is interfered | 雷克西制药公司 | 2019-02-19 | — | — | CN | disclosed |
| US-20190046541-A1 | ACETAMIDE THIENOTRIAZOLODIAZEPINES AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. | 2019-02-14 | — | — | US | disclosed |
| WO-2019032619-A1 | CHEMICALLY MODIFIED OLIGONUCLEOTIDES | PHIO PHARMACEUTICALS CORP. (US) | 2019-02-14 | — | — | WO | disclosed |
| US-20190048341-A1 | REDUCED SIZE SELF-DELIVERING NUCLEIC ACID COMPOUNDS TARGETING LONG NON-CODING RNA | RXI PHARMACEUTICALS CORPORATION (US) | 2019-02-14 | — | — | US | disclosed |
| WO-2019032936-A1 | LINCONSAMIDE ANTIBIOTICS AND USES THEREOF | PRESIDENT ADN FELLOWS OF HARVARD COLLEGE (US) | 2019-02-14 | — | — | WO | disclosed |
| WO-2019032961-A1 | TRIOXACARCIN-ANTIBODY CONJUGATES AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2019-02-14 | — | — | WO | disclosed |
| WO-2019032607-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2019-02-14 | — | — | WO | disclosed |
| WO-2019032956-A1 | LINCOSAMIDE ANTIBIOTICS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2019-02-14 | — | — | WO | disclosed |
| WO-2019032612-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2019-02-14 | — | — | WO | disclosed |
| WO-2019032941-A1 | LINCOSAMIDE ANTIBIOTICS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2019-02-14 | — | — | WO | disclosed |
| US-10201623-B2 | HSP90-targeted cardiac imaging and therapy | MEMORIAL SLOAN KETTERING CANCER CENTER (US) | 2019-02-12 | — | — | US | disclosed |
| US-10201618-B2 | Alkenyl substituted 2,5-piperazinediones, compositions, and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2019-02-12 | — | — | US | disclosed |
| US-10202400-B2 | Cortistatin analogues and syntheses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2019-02-12 | — | — | US | disclosed |
| US-20190038751-A1 | BRANCHED MULTI-FUNCTIONAL MACROMONOMERS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2019-02-07 | — | — | US | disclosed |
| US-20190038782-A1 | BRUSH-ARM STAR POLYMER IMAGING AGENTS AND USES THEREOF | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 2019-02-07 | — | — | US | disclosed |
| WO-2019025137-A1 | PROCESS FOR DEOXYFLUORINATION OF PHENOLS | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2019-02-07 | — | — | WO | disclosed |
| WO-2019025432-A1 | ANTICANCER PEPTIDES | IDP DISCOVERY PHARMA, S.L. (ES) | 2019-02-07 | — | — | WO | disclosed |
| WO-2019025433-A1 | ANTICANCER PEPTIDES | IDP DISCOVERY PHARMA, S.L. (ES) | 2019-02-07 | — | — | WO | disclosed |
| WO-2019028362-A1 | INHIBITORS OF PLASMA KALLIKREIN AND USES THEREOF | DYAX CORP. (US) | 2019-02-07 | — | — | WO | disclosed |
| US-20190038656-A1 | ANTHRANILYL-ADENOSINEMONOSULFAMATE ANALOGS AND USES THEREOF | Memorial Slooan-Kettering Cancer Center (US) | 2019-02-07 | — | — | US | disclosed |
| US-20190040021-A1 | FUNCTIONALIZED 1,2,4,5-TETRAZINE COMPOUNDS FOR USE IN BIOORTHOGONAL COUPLING REACTIONS | THE GENERAL HOSPITAL CORPORATION | 2019-02-07 | — | — | US | disclosed |
| EP-3438077-A1 | PROCESS FOR DEOXYFLUORINATION OF PHENOLS | Studiengesellschaft Kohle mbH (DE) | 2019-02-06 | — | — | EP | disclosed |
| WO-2019023651-A2 | SMALL MOLECULE MODULATORS OF THE ANDROGEN RECEPTOR | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2019-01-31 | — | — | WO | disclosed |
| WO-2019020649-A1 | ANTICANCER PEPTIDES | IDP DISCOVERY PHARMA, S.L. (ES) | 2019-01-31 | — | — | WO | disclosed |
| US-20190030171-A1 | PHOSPONATE LINKERS AND THEIR USE TO FACILITATE CELLULAR RETENTION OF COMPOUNDS | MERCK SHARP & DOHME CORP. (US) | 2019-01-31 | — | — | US | disclosed |
| US-20190031642-A1 | POLYCYCLIC INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 (CDK7) | PARAZA PHARMA, INC. (CA) | 2019-01-31 | — | — | US | disclosed |
| US-20190030067-A1 | CORE-TO-SURFACE POLYMERIZATION FOR THE SYNTHESIS OF STAR POLYMERS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2019-01-31 | — | — | US | disclosed |
| US-10189802-B2 | Aminoalcohol lipidoids and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2019-01-29 | — | — | US | disclosed |
| US-10188661-B2 | Topical dosage regimen | TOPOKINE THERAPEUTICS, INC. (US) | 2019-01-29 | — | — | US | disclosed |
| CN-109265400-A | Arginine methyltransferase inhibitor and application thereof | EPIZYME股份有限公司 | 2019-01-25 | — | — | CN | disclosed |
| US-20190023710-A1 | NOVEL COMPOUNDS AND USES THEREOF | KALA BIO, Inc. | 2019-01-24 | — | — | US | disclosed |
| US-20190022064-A1 | PRMT1 Inhibitors and Uses Thereof | Epizyme, Inc. | 2019-01-24 | — | — | US | disclosed |
| WO-2018144620-A9 | ANTI-FIBROTIC COMPOUNDS | CERTA THERAPEUTICS PTY LTD. (AU) | 2019-01-24 | — | — | WO | disclosed |
| EP-2693879-B1 | MIGRASTATINS AND USES THEREOF | SLOAN KETTERING INST CANCER RES (US) | 2019-01-23 | — | — | EP | disclosed |
| EP-3430031-A1 | PEPTIDES WITH ANTI-CANCER ACTIVITY | IDP Discovery Pharma, S.L. (ES) | 2019-01-23 | — | — | EP | disclosed |
| US-10184124-B2 | RNA interference in ocular indications | PHIO PHARMACEUTICALS CORP. (US) | 2019-01-22 | — | — | US | disclosed |
| WO-2019014429-A1 | COMPOUNDS FOR TAU PROTEIN DEGRADATION | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2019-01-17 | — | — | WO | disclosed |
| US-20190015411-A9 | COMBINATION THERAPY OF TRANSCRIPTION INHIBITORS AND KINASE INHIBITORS | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2019-01-17 | — | — | US | disclosed |
| US-20190016723-A9 | SUBSTRATE SELECTIVE INHIBITORS OF INSULIN-DEGRADING ENZYME (IDE) AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2019-01-17 | — | — | US | disclosed |
| EP-3426693-A1 | METHODS FOR MODULAR SYNTHESIS OF N-GLYCANS AND ARRAYS THEREOF | Academia Sinica (TW) | 2019-01-16 | — | — | EP | disclosed |
| EP-3426654-A1 | DIRECT PALLADIUM-CATALYZED AROMATIC FLUORINATION | President and Fellows of Harvard College (US) | 2019-01-16 | — | — | EP | disclosed |
| EP-2282735-B1 | PP2A MODULATORS FOR TREATING ALZHEIMER, PARKINSON, DIABETES | SIGNUM BIOSCIENCES INC (US) | 2019-01-16 | — | — | EP | disclosed |
| US-20190008986-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2019-01-10 | — | — | US | disclosed |
| WO-2019009956-A1 | FE/CU-MEDIATED KETONE SYNTHESIS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2019-01-10 | — | — | WO | disclosed |
| WO-2019010363-A1 | SYNTHESIS OF HALICHONDRINS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2019-01-10 | — | — | WO | disclosed |
| US-20190010181-A1 | TRITERPENE SAPONIN VARIANTS, METHODS OF SYNTHESIS AND USE THEREOF | MEMORIAL SLOAN-KETTERING CANCER CENTER | 2019-01-10 | — | — | US | disclosed |
| EP-2882736-B1 | PROCESSES FOR THE PREPARATION OF (S)-3-4-((4-(MORPHOLINOMETHYL) BENZYL)OXY)-1-OXOISOINDOLIN-2-YL) PIPERIDINE-2,6-DIONE AND PHARMACEUTICALLY ACCEPTABLE FORMS THEREOF | CELGENE CORP (US) | 2019-01-09 | — | — | EP | disclosed |
| CN-109136974-A | One kind (sp containing C2)-N key compound preparation method | 中国科学院上海有机化学研究所 | 2019-01-04 | — | — | CN | disclosed |
| CN-109152781-A | HCK as a therapeutic target in MYD88 mutant diseases | 达纳-法伯癌症研究所有限公司 | 2019-01-04 | — | — | CN | disclosed |
| WO-2019006426-A2 | BRANCHED MULTI-FUNCTIONAL MACROMONOMERS AND RELATED POLYMERS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2019-01-03 | — | — | WO | disclosed |
| WO-2019006425-A1 | BRUSH-ARM STAR POLYMER IMAGING AGENTS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2019-01-03 | — | — | WO | disclosed |
| WO-2019006422-A1 | CORE-TO-SURFACE POLYMERIZATION FOR THE SYNTHESIS OF STAR POLYMERS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2019-01-03 | — | — | WO | disclosed |
| US-20190002463-A1 | ANTI-PARASITIC COMPOUNDS AND USES THEREOF | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2019-01-03 | — | — | US | disclosed |
| US-20190000860-A1 | USE OF COMPOSITIONS MODULATING CHROMATIN STRUCTURE FOR GRAFT VERSUS HOST DISEASE (GVHD) | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2019-01-03 | — | — | US | disclosed |
| US-10167277-B2 | Activators of class I histone deacetlyases (HDACs) and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2019-01-01 | — | — | US | disclosed |
| US-10167263-B2 | Treatment of amyotrophic lateral sclerosis | NORTHWESTERN UNIVERSITY (US) | 2019-01-01 | — | — | US | disclosed |
| US-20180369144-A1 | LIPID FORMULATIONS FOR DELIVERY OF MESSENGER RNA | TRANSLATE BIO, INC. | 2018-12-27 | — | — | US | disclosed |
| US-20180369243-A9 | FUSED BICYCLIC PYRIMIDINE DERIVATIVES AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2018-12-27 | — | — | US | disclosed |
| US-20180371464-A1 | RNA INTERFERENCE IN DERMAL AND FIBROTIC INDICATIONS | RXI PHARMACEUTICALS CORPORATION (US) | 2018-12-27 | — | — | US | disclosed |
| US-20180369402-A1 | CONJUGATES OF TUMOR NECROSIS FACTOR INHIBITORS TO FUNCTIONALIZED POLYMERS | FISH & RICHARDSON PC | 2018-12-27 | — | — | US | disclosed |
| US-20180369249-A1 | PURINE COMPOUNDS POSSESSING ANTICANCER ACTIVITY | ACADEMIA SINICA (TW) | 2018-12-27 | — | — | US | disclosed |
| US-20180369230-A1 | TARGETED SELECTION OF PATIENTS FOR TREATMENT WITH SPECIFIC CORTISTATIN DERIVATIVES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2018-12-27 | — | — | US | disclosed |
| EP-2855558-B1 | POLYMERIZATION SYSTEM FOR THE COPOLYMERIZATION OF CO2 AND EPOXIDES AND RELATED METHOD | SAUDI ARAMCO TECH CO (SA) | 2018-12-26 | — | — | EP | disclosed |
| EP-3416950-A1 | MAX BINDERS AS MYC MODULATORS AND USES THEREOF | Massachusetts Institute of Technology (US) | 2018-12-26 | — | — | EP | disclosed |
| EP-3416958-A1 | ANTIFUNGAL COMPOUNDS AND USES THEREOF | Dana Farber Cancer Institute, Inc. (US) | 2018-12-26 | — | — | EP | disclosed |
| US-10160729-B2 | Hsp70 modulators and methods for making and using the same | MEMORIAL SLOAN KETTERING CANCER CENTER (US) | 2018-12-25 | — | — | US | disclosed |
| US-10160969-B2 | Chiral design | WAVE LIFE SCIENCES LTD. (SG) | 2018-12-25 | — | — | US | disclosed |
| US-10159749-B2 | Drug delivery polymer and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2018-12-25 | — | — | US | disclosed |
| CN-109071456-A | MAX binding agents as MYC modulators and uses thereof | 麻省理工学院 | 2018-12-21 | — | — | CN | disclosed |
| CN-109071423-A | Indoleamine-2, 3-dioxygenase (IDO) inhibitors | 益方生物科技（上海）有限公司 | 2018-12-21 | — | — | CN | disclosed |
| CN-109069508-A | EZH2 inhibitor and application thereof | 达纳-法伯癌症研究所股份有限公司 | 2018-12-21 | — | — | CN | disclosed |
| US-20180363050-A1 | MULTIPLEXING IN PARTITIONS USING PRIMER PARTICLES | BIO-RAD LABORATORIES, INC. | 2018-12-20 | — | — | US | disclosed |
| US-20180362573-A1 | NEUROACTIVE STEROIDS, COMPOSITIONS, AND USES THEREOF | Sage Therapeutics, LLC | 2018-12-20 | — | — | US | disclosed |
| US-20180362574-A1 | METHODS FOR TREATING POLYCYSTIC KIDNEY DISEASE AND POLYCYSTIC LIVER DISEASE | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2018-12-20 | — | — | US | disclosed |
| US-20180362483-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASES | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2018-12-20 | — | — | US | disclosed |
| EP-3414224-A1 | INHIBITOR OF INDOLEAMINE-2,3-DIOXYGENASE (IDO) | Inventisbio Inc. (KY) | 2018-12-19 | — | — | EP | disclosed |
| US-10155742-B2 | Halofuginol derivatives and their use in cosmetic and pharmaceutical compositions | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2018-12-18 | — | — | US | disclosed |
| WO-2018227012-A1 | POLYMER-LIPID MATERIALS FOR DELIVERY OF NUCLEIC ACIDS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2018-12-13 | — | — | WO | disclosed |
| US-20180354973-A1 | BIVALENT BROMODOMAIN INHIBITORS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2018-12-13 | — | — | US | disclosed |
| US-20180353435-A1 | POLYMER-LIPID MATERIALS FOR DELIVERY OF NUCLEIC ACIDS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2018-12-13 | — | — | US | disclosed |
| US-20180353517-A1 | METHODS AND COMPOSITIONS FOR REDUCING BODY FAT AND ADIPOCYTES | TOPOKINE THERAPEUTICS, INC. (US) | 2018-12-13 | — | — | US | disclosed |
| US-20180354954-A9 | HYDROPHOBICALLY TAGGED SMALL MOLECULES AS INDUCERS OF PROTEIN DEGRADATION | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2018-12-13 | — | — | US | disclosed |
| EP-3411034-A1 | SELECTIVE ESTROGEN RECEPTOR DEGRADERS AND USES THEREOF | Inventisbio Inc. (KY) | 2018-12-12 | — | — | EP | disclosed |
| CN-108976272-A | The disubstituted 19- norpregna hydride compounds of 3,3-, composition, and application thereof | 萨奇治疗股份有限公司 | 2018-12-11 | — | — | CN | disclosed |
| US-10150756-B2 | Diaminopyrimidine benzenesulfone derivatives and uses thereof | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2018-12-11 | — | — | US | disclosed |
| US-10150758-B2 | PRMT5 inhibitors and uses thereof | Epizyme, Inc. (US) | 2018-12-11 | — | — | US | disclosed |
| US-20180344733-A9 | 4,6-PYRIMIDINYLENE DERIVATIVES AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2018-12-06 | — | — | US | disclosed |
| WO-2018223056-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2018-12-06 | — | — | WO | disclosed |
| EP-3407916-A2 | PHOSPHONATE LINKERS AND THEIR USE TO FACILITATE CELLULAR RETENTION OF COMPOUNDS | Merck Sharp & Dohme Corp. (US) | 2018-12-05 | — | — | EP | disclosed |
| EP-2909204-B1 | GSK3 INHIBITORS AND METHODS OF USE THEREOF | BROAD INST INC (US) | 2018-12-05 | — | — | EP | disclosed |
| US-10144730-B2 | Inhibitors of c-Jun-N-terminal kinase (JNK) | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2018-12-04 | — | — | US | disclosed |
| WO-2018217766-A1 | KCC2 EXPRESSION ENHANCING COMPOUNDS AND USES THEREOF | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2018-11-29 | — | — | WO | disclosed |
| EP-2651448-B1 | WATER-SOLUBLE, NON-PEPTIDIC, NON-NUCLEOTIDIC PHOSPHORAMIDATE FUNCTIONALIZED POLYMERS | QUIAPEG PHARMACEUTICALS AB (SE) | 2018-11-28 | — | — | EP | disclosed |
| EP-3087080-B1 | CORTISTATIN ANALOGUES AND SYNTHESES AND USES THEREOF | HARVARD COLLEGE (US) | 2018-11-28 | — | — | EP | disclosed |
| EP-3406607-A1 | PRMT5 INHIBITORS CONTAINING A DIHYDRO- OR TETRAHYDROISOQUINOLINE AND USES THEREOF | Epizyme, Inc. (US) | 2018-11-28 | — | — | EP | disclosed |
| US-10138205-B2 | Artificial self-sufficient cytochrome P450s | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2018-11-27 | — | — | US | disclosed |
| US-10137122-B2 | Kinase inhibitors and methods of use thereof | THE BROAD INSTITUTE, INC. (US) | 2018-11-27 | — | — | US | disclosed |
| WO-2018213365-A1 | COMPOUNDS FOR TREATING DENGUE VIRUS INFECTION AND OTHER VIRAL INFECTIONS | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2018-11-22 | — | — | WO | disclosed |
| US-10130714-B2 | Enhanced anti-influenza agents conjugated with anti-inflammatory activity | ACADEMIA SINICA (TW) | 2018-11-20 | — | — | US | disclosed |
| US-20180327389-A1 | UREA DERIVATIVES AND USES THEREOF | KALA BIO, Inc. | 2018-11-15 | — | — | US | disclosed |
| US-20180327390-A1 | UREA DERIVATIVES AND USES THEREOF | KALA BIO, Inc. | 2018-11-15 | — | — | US | disclosed |
| US-20180327436-A1 | TRITERPENE SAPONIN ANALOGUES | ADJUVANCE TECHNOLOGIES, INC. (US) | 2018-11-15 | — | — | US | disclosed |
| US-10125124-B2 | Formation of macromolecules using iterative growth and related compounds | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2018-11-13 | — | — | US | disclosed |
| US-10125220-B2 | Functionalized polymers | QUIAPEG PHARMACEUTICALS AB (SE) | 2018-11-13 | — | — | US | disclosed |
| US-10124035-B2 | DISC-1 pathway activators in the control of neurogenesis | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2018-11-13 | — | — | US | disclosed |
| CN-108778289-A | TRITERPENE SAPONIN ANALOGUES | 佐剂技术公司 | 2018-11-09 | — | — | CN | disclosed |
| US-20180318456-A1 | COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS | LANTHEUS MEDICAL IMAGING, INC. (US) | 2018-11-08 | — | — | US | disclosed |
| US-20180319814-A1 | CORTISTATIN ANALOGUES AND SYNTHESES AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2018-11-08 | — | — | US | disclosed |
| US-20180319801-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASES | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2018-11-08 | — | — | US | disclosed |
| EP-2802572-B1 | HALOFUGINOL DERIVATIVES AND THEIR USE IN COSMETIC AND PHARMACEUTICAL COMPOSITIONS | HARVARD COLLEGE (US) | 2018-11-07 | — | — | EP | disclosed |
| EP-2734510-B1 | ACTIVATORS OF CLASS I HISTONE DEACETLYASES (HDACS) AND USES THEREOF | MASSACHUSETTS INST TECHNOLOGY (US) | 2018-11-07 | — | — | EP | disclosed |
| US-10117904-B2 | Use of anti-bacterial agents for the treatment of epithelial-related conditions | SIGNUM BIOSCIENCES, INC. (US) | 2018-11-06 | — | — | US | disclosed |
| US-10119972-B2 | Reactive labelling compounds and uses thereof | ACADEMIA SINICA (TW) | 2018-11-06 | — | — | US | disclosed |
| US-10118931-B2 | CARM1 inhibitors and uses thereof | Epizyme, Inc. (US) | 2018-11-06 | — | — | US | disclosed |
| CN-105339351-B | Arginine methyltransferase inhibitors and uses thereof | EPIZYME股份有限公司 | 2018-11-06 | — | — | CN | disclosed |
| US-10118918-B2 | PRMT5 inhibitors and uses thereof | Epizyme, Inc. (US) | 2018-11-06 | — | — | US | disclosed |
| US-10117934-B2 | Conjugated lipomers and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2018-11-06 | — | — | US | disclosed |
| WO-2018201076-A2 | MACROLIDES WITH MODIFIED DESOSAMINE SUGARS AND USES THEREOF | MACROLIDE PHARMACEUTICALS INC. (US) | 2018-11-01 | — | — | WO | disclosed |
| US-20180312473-A1 | PHENAZINE DERIVATIVES AS ANTIMICROBIAL AGENTS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED | 2018-11-01 | — | — | US | disclosed |
| WO-2018197663-A1 | ANTITUMORAL COMPOUNDS | PHARMA MAR, S.A. (ES) | 2018-11-01 | — | — | WO | disclosed |
| US-20180312529-A1 | Antitumoral Compounds | PHARMA MAR, S.A. (ES) | 2018-11-01 | — | — | US | disclosed |
| EP-2640700-B1 | AMINE-CONTAINING TRANSFECTION REAGENTS AND METHODS FOR MAKING AND USING SAME | LIFE TECHNOLOGIES CORP (US) | 2018-10-31 | — | — | EP | disclosed |
| EP-3394038-A1 | TARGETED SELECTION OF PATIENTS FOR TREATMENT WITH SPECIFIC CORTISTATIN DERIVATIVES | President and Fellows of Harvard College (US) | 2018-10-31 | — | — | EP | disclosed |
| EP-3395328-A1 | COMPOSITIONS AND METHODS FOR TOPICAL DELIVERY OF PROSTAGLANDINS TO SUBCUTANEOUS FAT | Topokine Therapeutics, Inc. (US) | 2018-10-31 | — | — | EP | disclosed |
| US-10111951-B2 | Human iNKT cell activation using glycolipids with altered glycosyl groups | ACADEMIA SINICA (TW) | 2018-10-30 | — | — | US | disclosed |
| US-10112957-B2 | Thiazolyl-containing compounds for treating proliferative diseases | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2018-10-30 | — | — | US | disclosed |
| US-10112927-B2 | Inhibitors of cyclin-dependent kinase 7 (CDK7) | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2018-10-30 | — | — | US | disclosed |
| CN-104888857-B | Catalyst And Method for synthetic polymer | 沙特阿美技术公司 | 2018-10-30 | — | — | CN | disclosed |
| WO-2018195355-A1 | TOPICAL DELIVERY OF NUCLEIC ACID COMPOUNDS | RXI PHARMACEUTICALS CORPORATION (US) | 2018-10-25 | — | — | WO | disclosed |
| WO-2018193428-A1 | MODIFIED OLIGOMERIC COMPOUNDS COMPRISING TRICYCLO-DNA NUCLEOSIDES AND USES THEREOF | SYNTHENA AG (CH) | 2018-10-25 | — | — | WO | disclosed |
| US-20180303822-A1 | PRMT5 INHIBITORS AND USES THEREOF | Epizyme, Inc. | 2018-10-25 | — | — | US | disclosed |
| EP-3389669-A1 | TRITERPENE SAPONIN VARIANTS, METHODS OF SYNTHESIS AND USE THEREOF | Memorial Sloan-Kettering Cancer Center (US) | 2018-10-24 | — | — | EP | disclosed |
| EP-3391898-A2 | STAPLED AND STITCHED POLYPEPTIDES AND USES THEREOF | President and Fellows of Harvard College (US) | 2018-10-24 | — | — | EP | disclosed |
| US-10105449-B2 | Drug delivery polymers and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2018-10-23 | — | — | US | disclosed |
| US-10106580-B2 | Enopeptins, uses thereof, and methods of synthesis thereto | BROWN UNIVERSITY (US) | 2018-10-23 | — | — | US | disclosed |
| US-10106833-B2 | Methods and compounds for identifying glycosyltransferase inhibitors | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2018-10-23 | — | — | US | disclosed |
| US-10106555-B2 | Max binders as MYC modulators and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2018-10-23 | — | — | US | disclosed |
| US-20180298048-A1 | MACROLIDES AND METHODS OF THEIR PREPARATION AND USE | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2018-10-18 | — | — | US | disclosed |
| US-20180297993-A1 | EZH2 INHIBITORS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2018-10-18 | — | — | US | disclosed |
| US-20180298010-A1 | PRMT5 INHIBITORS AND USES THEREOF | Epizyme, Inc. | 2018-10-18 | — | — | US | disclosed |
| US-20180297942-A1 | POLYAMINE SULFONAMIDES AND USES THEREOF | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2018-10-18 | — | — | US | disclosed |
| US-20180296680-A1 | SUPRAMOLECULAR MODIFICATION OF PROTEINS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2018-10-18 | — | — | US | disclosed |
| EP-3387128-A1 | MULTIPLEXING IN PARTITIONS USING MICROPARTICLES | Raindance Technologies Inc. (US) | 2018-10-17 | — | — | EP | disclosed |
| EP-3386484-A1 | COMPOSITIONS AND METHODS FOR DELIVERY OF THERAPEUTIC AGENTS | ModernaTX, Inc. (US) | 2018-10-17 | — | — | EP | disclosed |
| US-10100081-B2 | Trapping reagents for reactive metabolites screening | BIOGEN MA INC. (US) | 2018-10-16 | — | — | US | disclosed |
| WO-2018187590-A1 | REDUCTION OR ELIMINATION OF IMMUNE RESPONSES TO NON-INTRAVENOUS, E.G., SUBCUTANEOUSLY ADMINISTERED THERAPEUTIC PROTEINS | MODERNATX, INC. (US) | 2018-10-11 | — | — | WO | disclosed |
| WO-2018187630-A1 | TRICYCLIC COMPOUNDS AS GLYCOGEN SYNTHASE KINASE 3 (GSK3) INHIBITORS AND USES THEREOF | THE BROAD INSTITUTE, INC. (US) | 2018-10-11 | — | — | WO | disclosed |
| US-20180291035-A1 | MYC MODULATORS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2018-10-11 | — | — | US | disclosed |
| US-20180290982-A1 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | Epizyme, Inc. | 2018-10-11 | — | — | US | disclosed |
| US-20180289671-A1 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | Epizyme, Inc. | 2018-10-11 | — | — | US | disclosed |
| EP-3383852-A2 | COMPOUNDS FOR TREATING PROLIFERATIVE DISEASES | Children's Medical Center Corporation (US) | 2018-10-10 | — | — | EP | disclosed |
| EP-2635338-B1 | A UROLOGICAL DEVICE | COLOPLAST AS (DK) | 2018-10-10 | — | — | EP | disclosed |
| US-20180282343-A1 | CARM1 INHIBITORS AND USES THEREOF | Epizyme, Inc. | 2018-10-04 | — | — | US | disclosed |
| US-20180280551-A1 | LABELING OF ANTIBODIES | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2018-10-04 | — | — | US | disclosed |
| EP-2850090-B1 | CHEMOENZYMATIC METHODS FOR SYNTHESIZING MOENOMYCIN ANALOGS | HARVARD COLLEGE (US) | 2018-10-03 | — | — | EP | disclosed |
| EP-3380100-A2 | BIVALENT BROMODOMAIN INHIBITORS AND USES THEREOF | Dana-Farber Cancer Institute, Inc. (US) | 2018-10-03 | — | — | EP | disclosed |
| US-10086013-B2 | Amino acid-, peptide- and polypeptide-lipids, isomers, compositions, and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2018-10-02 | — | — | US | disclosed |
| US-10086054-B2 | RM2 antigens and use thereof | ACADEMIA SINICA (TW) | 2018-10-02 | — | — | US | disclosed |
| CN-108602825-A | Purine compounds having anticancer activity | 中央研究院 | 2018-09-28 | — | — | CN | disclosed |
| US-20180272003-A1 | Biodegradable Lipids for Delivery of Nucleic Acids | TRANSLATE BIO, INC. | 2018-09-27 | — | — | US | disclosed |
| US-20180272005-A1 | Biodegradable Lipids for Delivery of Nucleic Acids | TRANSLATE BIO, INC. (US) | 2018-09-27 | — | — | US | disclosed |
| US-20180273573-A1 | INHIBITORS OF MENAQUINONE BIOSYNTHESIS | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2018-09-27 | — | — | US | disclosed |
| US-20180272004-A1 | Biodegradable Lipids for Delivery of Nucleic Acids | TRANSLATE BIO, INC. | 2018-09-27 | — | — | US | disclosed |
| US-20180272002-A1 | Biodegradable Lipids for Delivery of Nucleic Acids | TRANSLATE BIO, INC. | 2018-09-27 | — | — | US | disclosed |
| WO-2018175844-A1 | SPIROKETALS AND USES THEREOF | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2018-09-27 | — | — | WO | disclosed |
| EP-3378480-A1 | METHODS AND COMPOSITIONS FOR TREATING OBESITY | Topokine Therapeutics, Inc. (US) | 2018-09-26 | — | — | EP | disclosed |
| US-10081603-B2 | Arginine methyltransferase inhibitors and uses thereof | EPIZYME INC. (US) | 2018-09-25 | — | — | US | disclosed |
| US-10081654-B2 | Stapled and stitched polypeptides and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2018-09-25 | — | — | US | disclosed |
| US-20180265589-A1 | GLYCATED CD59 PEPTIDES, THEIR PREPARATION, AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2018-09-20 | — | — | US | disclosed |
| US-20180265475-A1 | HALOGENATED QUINOLINE DERIVATIVES AS ANTIMICROBIAL AGENTS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2018-09-20 | — | — | US | disclosed |
| US-20180265478-A1 | PRMT1 INHIBITORS AND USES THEREOF | Epizyme, Inc. | 2018-09-20 | — | — | US | disclosed |
| US-20180265507-A1 | HOST TARGETED INHIBITORS OF DENGUE VIRUS AND OTHER VIRUSES | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2018-09-20 | — | — | US | disclosed |
| US-20180263925-A1 | METHODS FOR THE TREATMENT OF ALOPECIA AREATA UTILIZING GENE MODULATION APPROACHES | RXI PHARMACEUTICALS CORPORATION (US) | 2018-09-20 | — | — | US | disclosed |
| US-20180258233-A9 | BLOCK CO-POLY(METAL ORGANIC NANOSTRUCTURES) (BCPMONS) AND USES THEREOF | NATIONAL SCIENCE FOUNDATION | 2018-09-13 | — | — | US | disclosed |
| WO-2018165385-A1 | INHIBITORS OF MALT1 AND USES THEREOF | CORNELL UNIVERSITY (US) | 2018-09-13 | — | — | WO | disclosed |
| EP-3370730-A1 | TRITERPENE SAPONIN ANALOGUES | Adjuvance Technologies, Inc. (US) | 2018-09-12 | — | — | EP | disclosed |
| EP-3371149-A1 | POLYAMINE SULFONAMIDES AND USES THEREOF | University of Florida Research Foundation, Inc. (US) | 2018-09-12 | — | — | EP | disclosed |
| WO-2018160774-A1 | USES OF PYRIMIDOPYRIMIDINONES AS SIK INHIBITORS | THE GENERAL HOSPITAL CORPORATION (US) | 2018-09-07 | — | — | WO | disclosed |
| US-20180250414-A1 | PEPTIDE-BASED MULTIPLE-DRUG DELIVERY VEHICLE | ARIEL-UNIVERSITY RESEARCH AND DEVELOPMENT COMPANY LTD. (IL) | 2018-09-06 | — | — | US | disclosed |
| US-20180251598-A1 | FUNCTIONALIZED POLYMERS | QUIAPEG AB (SE) | 2018-09-06 | — | — | US | disclosed |
| US-20180250120-A1 | UROLOGICAL DEVICE ADAPTED FOR PLACEMENT IN A URETHRA OF A USER FOR TREATMENT OF INCONTINENCE | COLOPLAST A/S (DK) | 2018-09-06 | — | — | US | disclosed |
| US-20180251489-A1 | MALT1 INHIBITORS AND USES THEREOF | Cornell University Cornell Center for Technology Enterprise & Commercialization (CCTEC) (US) | 2018-09-06 | — | — | US | disclosed |
| US-20180251467-A1 | NOVEL COMPOUNDS AND USES THEREOF | KALA BIO, Inc. | 2018-09-06 | — | — | US | disclosed |
| EP-2935222-B1 | PRMT5 INHIBITORS AND USES THEREOF | EPIZYME INC (US) | 2018-09-05 | — | — | EP | disclosed |
| CN-108484449-A | Composition, method and system for synthesizing and using developer | 蓝瑟斯医学影像公司 | 2018-09-04 | — | — | CN | disclosed |
| CN-108472295-A | BIVALENT BROMODOMAIN INHIBITORS AND USES THEREOF | 达纳-法伯癌症研究所股份有限公司 | 2018-08-31 | — | — | CN | disclosed |
| CN-108472299-A | Acetamide thieno triazol diazacyclo heptantriene and application thereof | 达纳-法伯癌症研究所股份有限公司 | 2018-08-31 | — | — | CN | disclosed |
| CN-108472300-A | Cyano thiophene and triazol diazacyclo heptantriene and application thereof | 达纳-法伯癌症研究所股份有限公司 | 2018-08-31 | — | — | CN | disclosed |
| US-20180243064-A1 | KIT OF PARTS INCLUDING A UROLOGICAL DEVICE | COLOPLAST A/S (DK) | 2018-08-30 | — | — | US | disclosed |
| EP-3365446-A1 | REDUCED SIZE SELF-DELIVERING NUCLEIC ACID COMPOUNDS TARGETING LONG NON-CODING RNA | RXi Pharmaceuticals Corporation (US) | 2018-08-29 | — | — | EP | disclosed |
| US-10059693-B2 | Urea derivatives and uses thereof | KALA PHARMACEUTICALS, INC. (US) | 2018-08-28 | — | — | US | disclosed |
| US-10059692-B2 | Urea derivatives and uses thereof | KALA PHARMACEUTICALS, INC. (US) | 2018-08-28 | — | — | US | disclosed |
| US-20180237397-A1 | PYRAZOLE DERIVATIVES AS ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | Epizyme, Inc. | 2018-08-23 | — | — | US | disclosed |
| US-20180237407-A1 | PHENYLSULFONAMIDO-BENZOFURAN DERIVATIVES AND USES THEREOF IN THE TREATMENT OF PROLIFERATIVE DISEASES | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2018-08-23 | — | — | US | disclosed |
| WO-2018152436-A1 | PHENAZINE DERIVATIVES AS ANTIMICROBIAL AGENTS | UNIVERSITY OF RESEARCH FOUNDATION, INCORPORATED (US) | 2018-08-23 | — | — | WO | disclosed |
| WO-2018151951-A1 | ANALOGS OF VINCAMINE AND USES THEREOF | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2018-08-23 | — | — | WO | disclosed |
| US-20180237406-A1 | PHENYLSULFONAMIDO-BENZOFURAN DERIVATIVES AND USES THEREOF IN THE TREATMENT OF PROLIFERATIVE DISEASES | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2018-08-23 | — | — | US | disclosed |
| EP-3363434-A1 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | Epizyme Inc (US) | 2018-08-22 | — | — | EP | disclosed |
| EP-3362465-A1 | PEPTIDE-BASED MULTIPLE-DRUG DELIVERY VEHICLE | Ariel-University Research and Development Company Ltd. (IL) | 2018-08-22 | — | — | EP | disclosed |
| US-10052284-B2 | Lipid formulations for delivery of messenger RNA | TRANSLATE BIO, INC. (US) | 2018-08-21 | — | — | US | disclosed |
| US-20180221379-A1 | USES OF SALT-INDUCIBLE KINASE (SIK) INHIBITORS | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2018-08-09 | — | — | US | disclosed |
| US-20180221504-A1 | TRIOXACARCINS, TRIOXACARCIN-ANTIBODY CONJUGATES, AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2018-08-09 | — | — | US | disclosed |
| WO-2018144620-A1 | ANTI-FIBROTIC COMPOUNDS | SHIRE HUMAN GENETIC THERAPIES, INC. (US) | 2018-08-09 | — | — | WO | disclosed |
| EP-3355922-A2 | COMBINATION THERAPY OF BROMODOMAIN INHIBITORS AND CHECKPOINT BLOCKADE | Dana Farber Cancer Institute, Inc. (US) | 2018-08-08 | — | — | EP | disclosed |
| EP-3356447-A1 | INHIBITORS OF MENAQUINONE BIOSYNTHESIS | Memorial Sloan-Kettering Cancer Center (US) | 2018-08-08 | — | — | EP | disclosed |
| EP-3357931-A1 | METHODS OF SYNTHESIS OF TRITERPENE PROSAPOGENINS AND TRITERPENE SAPONINS | Sloan Kettering Institute For Cancer Research (US) | 2018-08-08 | — | — | EP | disclosed |
| US-10039816-B2 | Siderophore-based immunization against gram-negative bacteria | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2018-08-07 | — | — | US | disclosed |
| US-10039748-B2 | PRMT1 inhibitors and uses thereof | Epizyme, Inc. (US) | 2018-08-07 | — | — | US | disclosed |
| CN-108358812-A | Amine-containing transfection reagent and its preparation and application | 生命科技公司 | 2018-08-03 | — | — | CN | disclosed |
| US-20180216107-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2018-08-02 | — | — | US | disclosed |
| US-20180214566-A1 | COMPOSITIONS AND METHODS RELATED TO SCAVENGER PARTICLES | NANOTICS, LLC | 2018-08-02 | — | — | US | disclosed |
| US-20180216108-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2018-08-02 | — | — | US | disclosed |
| US-20180208600-A1 | BICYCLIC HETEROCYCLIC DERIVATIVES AS MNK1 AND MNK2 MODULATORS AND USES THEREOF | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2018-07-26 | — | — | US | disclosed |
| US-20180208712-A1 | POLYMERIZABLE SULFONAMIDE COMPOUNDS AND POLYMERS THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2018-07-26 | — | — | US | disclosed |
| US-20180208699-A1 | POLYMERS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2018-07-26 | — | — | US | disclosed |
| US-20180200374-A1 | AMINE-CONTAINING TRANSFECTION REAGENTS AND METHODS FOR MAKING AND USING SAME | Life Technologies Corporation | 2018-07-19 | — | — | US | disclosed |
| US-20180200372-A1 | COMPOSITIONS AND METHODS FOR TOPICAL DELIVERY OF PROSTAGLANDINS TO SUBCUTANEOUS FAT | TOPOKINE THERAPEUTICS, INC. | 2018-07-19 | — | — | US | disclosed |
| EP-3347018-A2 | INHIBITORS OF CYCLIN-DEPENDENT KINASES | Dana-Farber Cancer Institute, Inc. (US) | 2018-07-18 | — | — | EP | disclosed |
| EP-3347020-A1 | ACETAMIDE THIENOTRIAZOLODIAZEPINES AND USES THEREOF | Dana-Farber Cancer Institute, Inc. (US) | 2018-07-18 | — | — | EP | disclosed |
| EP-3347021-A1 | CYANO THIENOTRIAZOLODIAZEPINES AND USES THEREOF | Dana-Farber Cancer Institute, Inc. (US) | 2018-07-18 | — | — | EP | disclosed |
| EP-2970135-B1 | PYRAZOLE DERIVATIVES AS PRMT1 INHIBITORS AND USES THEREOF | EPIZYME INC (US) | 2018-07-18 | — | — | EP | disclosed |
| CN-108289957-A | COMBINATION THERAPY OF BROMODOMAIN INHIBITORS AND CHECKPOINT BLOCKADE | 达纳-法伯癌症研究所股份有限公司 | 2018-07-17 | — | — | CN | disclosed |
| US-10023536-B2 | Suprametallogels and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2018-07-17 | — | — | US | disclosed |
| US-10022455-B2 | Biodegradable lipids for delivery of nucleic acids | TRANSLATE BIO, INC. (US) | 2018-07-17 | — | — | US | disclosed |
| WO-2018129188-A1 | METHODS FOR ASSEMBLING SCAVENGING PARTICLES | NANOTICS, LLC (US) | 2018-07-12 | — | — | WO | disclosed |
| WO-2018129207-A1 | METHODS FOR ASSEMBLING SCAVENGING PARTICLES | NANOTICS, LLC (US) | 2018-07-12 | — | — | WO | disclosed |
| US-20180194771-A1 | BICYCLIC ALKYNE DERIVATIVES AND USES THEREOF | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2018-07-12 | — | — | US | disclosed |
| US-20180195066-A1 | METHODS FOR TREATING NEUROLOGICAL DISORDERS USING A SYNERGISTIC SMALL MOLECULE AND NUCLEIC ACIDS THERAPEUTIC APPROACH | RXI PHARMACEUTICALS CORPORATION (US) | 2018-07-12 | — | — | US | disclosed |
| US-20180194739-A1 | METHODS TO TREAT LYMPHOPLASMACYTIC LYMPHOMA | DANA-FARBER CANCER INSTITUTE, INC. | 2018-07-12 | — | — | US | disclosed |
| US-20180194768-A1 | SUBSTRATE SELECTIVE INHIBITORS OF INSULIN DEGRADING ENZYME (IDE) AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2018-07-12 | — | — | US | disclosed |
| US-20180195072-A1 | NUCLEIC ACID MOLECULES TARGETING SUPEROXIDE DISMUTASE 1 (SOD1) | RXI PHARMACEUTICALS CORPORATION (US) | 2018-07-12 | — | — | US | disclosed |
| EP-2424834-B1 | SYNTHESIS OF TETRACYCLINES AND INTERMEDIATES THEREOF | HARVARD COLLEGE (US) | 2018-07-11 | — | — | EP | disclosed |
| US-10017477-B2 | Janus kinase inhibitors and uses thereof | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2018-07-10 | — | — | US | disclosed |
| US-10017520-B2 | Myc modulators and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2018-07-10 | — | — | US | disclosed |
| US-20180186798-A1 | PRMT5 INHIBITORS AND USES THEREOF | Epizyme, Inc. | 2018-07-05 | — | — | US | disclosed |
| US-20180186780-A1 | METHODS TO TREAT LYMPHOPLASMACYTIC LYMPHOMA | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2018-07-05 | — | — | US | disclosed |
| EP-3341007-A1 | MALT1 INHIBITORS AND USES THEREOF | Cornell University (US) | 2018-07-04 | — | — | EP | disclosed |
| US-10010535-B2 | Desferrithiocin analogs and uses thereof | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2018-07-03 | — | — | US | disclosed |
| US-10010621-B2 | Conjugates of biologically active molecules to functionalized polymers | QUIAPEG PHARMACEUTICALS AB (SE) | 2018-07-03 | — | — | US | disclosed |
| US-20180179242-A1 | CATALYSTS AND METHODS FOR POLYMER SYNTHESIS | NOVOMER, INC. | 2018-06-28 | — | — | US | disclosed |
| CN-104114605-B | Method for polymer synthesis | 沙特阿美技术公司 | 2018-06-22 | — | — | CN | disclosed |
| US-20180170957-A1 | HUMAN iNKT CELL ACTIVATION USING GLYCOLIPIDS | ACADEMIA SINICA (TW) | 2018-06-21 | — | — | US | disclosed |
| US-20180169097-A1 | COMBINATION THERAPY OF TRANSCRIPTION INHIBITORS AND KINASE INHIBITORS | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2018-06-21 | — | — | US | disclosed |
| US-20180170883-A1 | HSP70 MODULATORS AND METHODS FOR MAKING AND USING THE SAME | MEMORIAL SLOAN KETTERING CANCER CENTER | 2018-06-21 | — | — | US | disclosed |
| US-20180169111-A1 | METHODS AND COMPOSITIONS FOR TOPICAL DELIVERY OF PROSTAGLANDINS TO SUBCUTANEOUS FAT | TOPOKINE THERAPEUTICS, INC. (US) | 2018-06-21 | — | — | US | disclosed |
| EP-3334713-A1 | PHENYLSULFONAMIDO-BENZOFURAN DERIVATIVES AND USES THEREOF IN THE TREATMENT OF PROLIFERATIVE DISEASES | Memorial Sloan Kettering Cancer Center (US) | 2018-06-20 | — | — | EP | disclosed |
| US-10000483-B2 | Bone marrow on X chromosome kinase (BMX) inhibitors and uses thereof | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2018-06-19 | — | — | US | disclosed |
| US-20180162862-A1 | INHIBITORS OF BACTERIAL GLYCOSYL TRANSFERASES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2018-06-14 | — | — | US | disclosed |
| WO-2018106738-A1 | BRUSH-ARM STAR POLYMERS, CONJUGATES AND PARTICLES, AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2018-06-14 | — | — | WO | disclosed |
| WO-2018106922-A1 | N-ARYLATED ANALOGUES AND USES THEREOF | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2018-06-14 | — | — | WO | disclosed |
| US-20180162847-A1 | PRMT5 INHIBITORS CONTAINING A DIHYDRO- OR TETRAHYDROISOQUINOLINE AND USES THEREOF | Epizyme, Inc. (US) | 2018-06-14 | — | — | US | disclosed |
| US-20180161295-A1 | TREATMENT OF CLOSED HEAD INJURY AND HEMORRHAGIC STROKE WITH HBED | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2018-06-14 | — | — | US | disclosed |
| US-9994582-B2 | Cortistatin analogues and syntheses and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2018-06-12 | — | — | US | disclosed |
| US-9993327-B2 | Urological device having a bladder retainer and a valve | COLOPLAST A/S (DK) | 2018-06-12 | — | — | US | disclosed |
| CN-108135923-A | Target superoxide dismutase 1（SOD1）Nucleic acid molecules | 阿克赛医药公司 | 2018-06-08 | — | — | CN | disclosed |
| CN-108135921-A | Oligonucleotide compositions and methods thereof | 波涛生命科学有限公司 | 2018-06-08 | — | — | CN | disclosed |
| CN-108135850-A | MODULAR COMPOSITIONS FOR SCAVENGING SOLUBLE BIOMOLECULES AND METHODS RELATED THERETO | 纳米提克斯有限责任公司 | 2018-06-08 | — | — | CN | disclosed |
| CN-108137492-A | Oligonucleotide compositions and methods thereof | 波涛生命科学有限公司 | 2018-06-08 | — | — | CN | disclosed |
| WO-2018099946-A1 | NOVEL BICYCLIC NUCLEOSIDES AND OLIGOMERS PREPARED THEREFROM | Universität Bern (CH) | 2018-06-07 | — | — | WO | disclosed |
| WO-2018100532-A1 | COMBINATION THERAPY | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2018-06-07 | — | — | WO | disclosed |
| WO-2018100536-A1 | METHODS OF TREATING CANCER | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2018-06-07 | — | — | WO | disclosed |
| WO-2018100534-A1 | COMBINATION THERAPY | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2018-06-07 | — | — | WO | disclosed |
| WO-2018100535-A1 | COMBINATION THERAPY | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2018-06-07 | — | — | WO | disclosed |
| WO-2018102372-A1 | INHIBITOR-FUNCTIONALIZED ULTRASMALL NANOPARTICLES AND METHODS THEREOF | MEMORIAL SLOAN KETTERING CANCER CENTER (US) | 2018-06-07 | — | — | WO | disclosed |
| US-20180155361-A1 | PALLADIUM-MEDIATED KETOLIZATION | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2018-06-07 | — | — | US | disclosed |
| US-20180155761-A1 | CELL-PERMEABLE PROBES FOR IDENTIFICATION AND IMAGING OF SIALIDASES | ACADEMIA SINICA (TW) | 2018-06-07 | — | — | US | disclosed |
| US-20180153894-A1 | FUSED BICYCLIC PYRIMIDINE DERIVATIVES AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2018-06-07 | — | — | US | disclosed |
| EP-3330276-A1 | NOVEL BICYCLIC NUCLEOSIDES AND OLIGOMERS PREPARED THEREFROM | Universität Bern (CH) | 2018-06-06 | — | — | EP | disclosed |
| EP-3328362-A1 | MODULAR COMPOSITIONS FOR SCAVENGING SOLUBLE BIOMOLECULES AND METHODS RELATED THERETO | Nanotics, LLC (US) | 2018-06-06 | — | — | EP | disclosed |
| EP-3330252-A2 | ISOPRENYL COMPOUNDS AND METHODS THEREOF | Signum Biosciences, Inc. (US) | 2018-06-06 | — | — | EP | disclosed |
| US-9988386-B2 | Compounds for treatment of diseases of abnormal angiogenesis or aberrant growth factors and uses thereof | Kata Pharmaceuticals, Inc. (US) | 2018-06-05 | — | — | US | disclosed |
| US-9987112-B2 | Method of treating urinary incontinence | COLOPLAST A/S (DK) | 2018-06-05 | — | — | US | disclosed |
| WO-2018098361-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASE 12 (CDK12) AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2018-05-31 | — | — | WO | disclosed |
| WO-2018098367-A1 | INHIBITORS OF INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASES AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2018-05-31 | — | — | WO | disclosed |
| US-20180147298-A1 | COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS | MODERNATX, INC. (US) | 2018-05-31 | — | — | US | disclosed |
| EP-3324978-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | Wave Life Sciences Ltd. (SG) | 2018-05-30 | — | — | EP | disclosed |
| US-9982009-B2 | Methods for treating polycystic kidney disease and polycystic liver disease | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2018-05-29 | — | — | US | disclosed |
| US-9982257-B2 | Chiral control | WAVE LIFE SCIENCES LTD. (SG) | 2018-05-29 | — | — | US | disclosed |
| US-9981030-B2 | Glycan conjugates and use thereof | ACADEMIA SINICA (TW) | 2018-05-29 | — | — | US | disclosed |
| US-9982005-B2 | Macrolides and methods of their preparation and use | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2018-05-29 | — | — | US | disclosed |
| US-9981038-B2 | Photoswitchable HDAC inhibitors | THE GENERAL HOSPITAL CORPORATION (US) | 2018-05-29 | — | — | US | disclosed |
| US-20180140581-A1 | METABOLICALLY PROGRAMMED METAL CHELATORS AND USES THEREOF | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2018-05-24 | — | — | US | disclosed |
| EP-2280987-B1 | TRITERPENE SAPONINS, METHODS OF SYNTHESIS, AND USES THEREOF | SLOAN KETTERING INST CANCER RES (US) | 2018-05-23 | — | — | EP | disclosed |
| US-9975872-B2 | Processes for the preparation of (s)-3-(4-((4-(morpholinomethyl)benzyl)oxy)-1-oxoisoindolin-2-yl)piperidine-2,6-dione and pharmaceutically acceptable forms thereof | CELGENE CORPORATION (US) | 2018-05-22 | — | — | US | disclosed |
| US-9975896-B2 | Inhibitors of transcription factors and uses thereof | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2018-05-22 | — | — | US | disclosed |
| US-20180133225-A1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | KALA BIO, Inc. | 2018-05-17 | — | — | US | disclosed |
| US-20180135134-A1 | TARGETED SELECTION OF PATIENTS FOR TREATMENT WITH CORTISTATIN DERIVATIVES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2018-05-17 | — | — | US | disclosed |
| US-20180134708-A1 | MITRAGYNINE ANALOGS AND USES THEREOF | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2018-05-17 | — | — | US | disclosed |
| US-20180134725-A1 | CORTISTATIN ANALOGUES, SYNTHESES, AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2018-05-17 | — | — | US | disclosed |
| EP-3321268-A1 | BICYCLIC HETEROARYL DERIVATIVES AS MNK1 AND MNK2 MODULATORS AND USES THEREOF | Agency For Science, Technology And Research (SG) | 2018-05-16 | — | — | EP | disclosed |
| US-9969679-B2 | Anti-proliferative compounds and uses thereof | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2018-05-15 | — | — | US | disclosed |
| US-9969739-B2 | Tricyclic chiral compounds and their use in asymmetric catalysis | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2018-05-15 | — | — | US | disclosed |
| CN-108025089-A | Oligonucleotide composition and its method | 波涛生命科学有限公司 | 2018-05-11 | — | — | CN | disclosed |
| EP-3316889-A1 | CORTISTATIN ANALOGUES AND SYNTHESES AND USES THEREOF | President and Fellows of Harvard College (US) | 2018-05-09 | — | — | EP | disclosed |
| US-9963702-B2 | RNA interference in dermal and fibrotic indications | RXI PHARMACEUTICALS CORPORATION (US) | 2018-05-08 | — | — | US | disclosed |
| WO-2018081456-A1 | HIGHLY ACTIVE SELF-SUFFICIENT NITRATION BIOCATALYSTS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2018-05-03 | — | — | WO | disclosed |
| US-20180118778-A1 | CORTISTATIN ANALOGUES AND SYNTHESES AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2018-05-03 | — | — | US | disclosed |
| EP-3313530-A1 | 4,6-PYRIMIDINYLENE DERIVATIVES AND USES THEREOF | Dana Farber Cancer Institute, Inc. (US) | 2018-05-02 | — | — | EP | disclosed |
| EP-3313529-A1 | FUSED BICYCLIC PYRIMIDINE DERIVATIVES AND USES THEREOF | Dana Farber Cancer Institute, Inc. (US) | 2018-05-02 | — | — | EP | disclosed |
| US-20180111956-A1 | SYNTHESIS OF DESOSAMINES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2018-04-26 | — | — | US | disclosed |
| US-20180110778-A1 | 4,6-PYRIMIDINYLENE DERIVATIVES AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2018-04-26 | — | — | US | disclosed |
| EP-3311777-A1 | A BIOMATERIAL | Coloplast A/S (DK) | 2018-04-25 | — | — | EP | disclosed |
| EP-3310764-A1 | ALKENYL SUBSTITUTED 2,5-PIPERAZINEDIONES AND THEIR USE IN COMPOSITIONS FOR DELIVERING AN AGENT TO A SUBJECT OR CELL | Massachusetts Institute of Technology (US) | 2018-04-25 | — | — | EP | disclosed |
| US-9951074-B2 | Dihydropteridinone derivatives and uses thereof | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2018-04-24 | — | — | US | disclosed |
| US-9951096-B2 | Catalysts and methods for polymer synthesis | SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) | 2018-04-24 | — | — | US | disclosed |
| CN-107936076-A | Neuroactive steroids, composition, and application thereof | 萨奇治疗股份有限公司 | 2018-04-20 | — | — | CN | disclosed |
| CN-104487485-B | polycarbonate polyol composition and method | 沙特阿美技术公司 | 2018-04-20 | — | — | CN | disclosed |
| US-20180105508-A1 | INHIBITORS OF PHOSPHOGLYCERATE DEHYDROGENASE (PHGDH) AND USES THEREOF | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2018-04-19 | — | — | US | disclosed |
| US-20180104246-A1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | KALA BIO, Inc. | 2018-04-19 | — | — | US | disclosed |
| US-20180105497-A1 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2018-04-19 | — | — | US | disclosed |
| EP-3308822-A1 | A UROLOGICAL DEVICE | Coloplast A/S (DK) | 2018-04-18 | — | — | EP | disclosed |
| EP-3307728-A1 | COMBINATION THERAPY OF TRANSCRIPTION INHIBITORS AND KINASE INHIBITORS | Dana Farber Cancer Institute, Inc. (US) | 2018-04-18 | — | — | EP | disclosed |
| US-9943504-B2 | Arginine methyltransferase inhibitors and uses thereof | Epizyme, Inc. (US) | 2018-04-17 | — | — | US | disclosed |
| US-9944607-B2 | Thiohydantoin derivatives and uses thereof | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2018-04-17 | — | — | US | disclosed |
| CN-107915751-A | Therapeutic compound and its purposes | 卡拉制药公司 | 2018-04-17 | — | — | CN | disclosed |
| US-20180100001-A1 | BIFUNCTIONAL STAPLED POLYPEPTIDES AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2018-04-12 | — | — | US | disclosed |
| WO-2018067702-A1 | BOTTLEBRUSH COPOLYMERS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2018-04-12 | — | — | WO | disclosed |
| WO-2018067973-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2018-04-12 | — | — | WO | disclosed |
| US-20180098987-A1 | PRMT5 Inhibitors and Uses Thereof | Epizyme, Inc. (US) | 2018-04-12 | — | — | US | disclosed |
| EP-3303338-A1 | INHIBITORS OF BACTERIAL GLYCOSYL TRANSFERASES | President and Fellows of Harvard College (US) | 2018-04-11 | — | — | EP | disclosed |
| CN-104159890-B | Compositions, methods, and systems for synthesis and use of imaging agents | 蓝瑟斯医学影像公司 | 2018-04-10 | — | — | CN | disclosed |
| US-20180094099-A1 | BOTTLEBRUSH COPOLYMERS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2018-04-05 | — | — | US | disclosed |
| US-20180093990-A1 | HYDROPHOBICALLY TAGGED SMALL MOLECULES AS INDUCERS OF PROTEIN DEGRADATION | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2018-04-05 | — | — | US | disclosed |
| CN-103380113-B | Amine-containing transfection reagents and methods of making and using same | 生命科技公司 | 2018-03-30 | — | — | CN | disclosed |
| US-9926291-B2 | Synthesis of thiohydantoins | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2018-03-27 | — | — | US | disclosed |
| CN-107848988-A | Alkenyl substituted 2, 5-piperazinediones and their use in compositions for delivering an agent to a subject or cell | 麻省理工学院 | 2018-03-27 | — | — | CN | disclosed |
| CN-107847763-A | Targeted selection of patients eligible for treatment with cortistatin derivatives | 哈佛学院院长等 | 2018-03-27 | — | — | CN | disclosed |
| CN-105228997-B | Carm1 inhibitors and uses thereof | EPIZYME股份有限公司 | 2018-03-27 | — | — | CN | disclosed |
| WO-2018050794-A1 | PROCESS FOR PREPARING OF CAROTENOID MONO-ESTERS | BASF SE (DE) | 2018-03-22 | — | — | WO | disclosed |
| WO-2018050793-A1 | PROCESS FOR PREPARING PHOSPHONIUM SALT ESTERS AS BUILDING BLOCKS FOR CAROTENOIDES | BASF SE (DE) | 2018-03-22 | — | — | WO | disclosed |
| WO-2018050795-A1 | PROCESS FOR PREPARING OF CAROTENOID MONO-ESTERS | BASF SE (DE) | 2018-03-22 | — | — | WO | disclosed |
| WO-2018050792-A1 | PROCESS FOR PREPARING ESTERS OF 12'-APOCAROTENALS AS BUILDING BLOCKS FOR CAROTENOIDS | BASF SE (DE) | 2018-03-22 | — | — | WO | disclosed |
| EP-3294418-A1 | TARGETED SELECTION OF PATIENTS FOR TREATMENT WITH CORTISTATIN DERIVATIVES | President and Fellows of Harvard College (US) | 2018-03-21 | — | — | EP | disclosed |
| EP-3294298-A1 | CORTISTATIN ANALOGUES, SYNTHESES, AND USES THEREOF | President and Fellows of Harvard College (US) | 2018-03-21 | — | — | EP | disclosed |
| US-9919064-B2 | Compositions, methods, and systems for the synthesis and use of imaging agents | LANTHEUS MEDICAL IMAGING, INC. (US) | 2018-03-20 | — | — | US | disclosed |
| EP-2935243-B1 | PRMT5 INHIBITORS CONTAINING A DIHYDRO- OR TETRAHYDROISOQUINOLINE AND USES THEREOF | EPIZYME INC (US) | 2018-03-14 | — | — | EP | disclosed |
| EP-2453908-B1 | BIFUNCTIONAL STAPLED POLYPEPTIDES AND USES THEREOF | HARVARD COLLEGE (US) | 2018-03-14 | — | — | EP | disclosed |
| EP-3291676-A1 | MITRAGYNINE ANALOGS AND USES THEREOF | Memorial Sloan Kettering Cancer Center (US) | 2018-03-14 | — | — | EP | disclosed |
| US-9914956-B2 | Cell-permeable probes for identification and imaging of sialidases | ACADEMIA SINICA (TW) | 2018-03-13 | — | — | US | disclosed |
| US-20180064824-A1 | CONJUGATE BASED SYSTEMS FOR CONTROLLED DRUG DELIVERY | MERCK SHARP & DOHME CORP. (US) | 2018-03-08 | — | — | US | disclosed |
| US-20180066008-A1 | MACROLIDES WITH MODIFIED DESOSAMINE SUGARS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2018-03-08 | — | — | US | disclosed |
| EP-2582836-B1 | PRPK-TPRKB MODULATORS AND USES THEREOF | TAIHO PHARMACEUTICAL CO LTD (JP) | 2018-03-07 | — | — | EP | disclosed |
| EP-3288557-A1 | METABOLICALLY PROGRAMMED METAL CHELATORS AND USES THEREOF | University of Florida Research Foundation, Inc. (US) | 2018-03-07 | — | — | EP | disclosed |
| EP-2513200-B1 | A BIOMATERIAL | COLOPLAST AS (DK) | 2018-03-07 | — | — | EP | disclosed |
| US-9908887-B2 | PRMT5 inhibitors and uses thereof | Epizyme, Inc. (US) | 2018-03-06 | — | — | US | disclosed |
| US-9908872-B2 | Methods to treat lymphoplasmacytic lymphoma | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2018-03-06 | — | — | US | disclosed |
| US-9908886-B2 | Bicyclic heterocyclic derivatives as MNK1 and MNK2 modulators and uses thereof | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2018-03-06 | — | — | US | disclosed |
| US-20180057565-A1 | STABILIZED POLYPEPTIDE INSULIN RECEPTOR MODULATORS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2018-03-01 | — | — | US | disclosed |
| EP-2970134-B1 | PYRAZOLE DERIVATIVES AS PRMT1 INHIBITORS AND USES THEREOF | EPIZYME INC (US) | 2018-02-28 | — | — | EP | disclosed |
| EP-2367798-B1 | PYRAZOLONE DERIVATIVES USEFUL IN THE TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS | UNIV NORTHWESTERN (US) | 2018-02-28 | — | — | EP | disclosed |
| US-9902986-B2 | Enterobactin conjugates and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2018-02-27 | — | — | US | disclosed |
| US-9902705-B2 | Functionalized 1,2,4,5-tetrazine compounds for use in bioorthogonal coupling reactions | THE GENERAL HOSPITAL CORPORATION (US) | 2018-02-27 | — | — | US | disclosed |
| US-9902985-B2 | Chemoenzymatic methods for synthesizing moenomycin analogs | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2018-02-27 | — | — | US | disclosed |
| US-9901642-B2 | Amine-containing transfection reagents and methods for making and using same | Life Technologies Corporation (US) | 2018-02-27 | — | — | US | disclosed |
| WO-2018035416-A1 | REAGENTS AND METHODS FOR GLYCOSYLATION | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2018-02-22 | — | — | WO | disclosed |
| EP-3056487-B1 | SYNTHESIS OF ENONE INTERMEDIATE | HARVARD COLLEGE (US) | 2018-02-21 | — | — | EP | disclosed |
| EP-3283060-A1 | BOLAAMPHIPHILIC COMPOUNDS, COMPOSITIONS AND USES THEREOF | Lauren Sciences LLC (US) | 2018-02-21 | — | — | EP | disclosed |
| US-9895443-B2 | Multi-tailed lipids and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2018-02-20 | — | — | US | disclosed |
| CN-107708693-A | Metal-chelator of Metabolic programming and application thereof | 佛罗里达大学研究基金会 | 2018-02-16 | — | — | CN | disclosed |
| US-20180044291-A1 | ARTIFICIAL SELF-SUFFICIENT CYTOCHROME P450S | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED | 2018-02-15 | — | — | US | disclosed |
| US-9889205-B2 | Glucose-responsive insulin conjugates | MERCK SHARP & DOHME CORP. (US) | 2018-02-13 | — | — | US | disclosed |
| US-20180036333-A9 | AMINO ACID-, PEPTIDE- AND POLYPEPTIDE-LIPIDS, ISOMERS, COMPOSITIONS, AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2018-02-08 | — | — | US | disclosed |
| US-20180036376-A1 | BOLAAMPHIPHILIC COMPOUNDS, COMPOSITIONS AND USES THEREOF | LAUREN SCIENCES LLC (US) | 2018-02-08 | — | — | US | disclosed |
| US-20180037573-A1 | UREA DERIVATIVES AND USES THEREOF | KALA BIO, Inc. | 2018-02-08 | — | — | US | disclosed |
| US-20180037572-A1 | UREA DERIVATIVES AND USES THEREOF | KALA BIO, Inc. | 2018-02-08 | — | — | US | disclosed |
| US-20180036415-A9 | DRUG DELIVERY POLYMER AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2018-02-08 | — | — | US | disclosed |
| EP-3277701-A1 | SYNTHESIS OF DESOSAMINES | President and Fellows of Harvard College (US) | 2018-02-07 | — | — | EP | disclosed |
| US-9884867-B2 | Bicyclic alkyne derivatives and uses thereof | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2018-02-06 | — | — | US | disclosed |
| US-9884125-B2 | Glucose-responsive insulin conjugates | MERCK SHARP & DOHME CORP. (US) | 2018-02-06 | — | — | US | disclosed |
| US-9885037-B2 | — | — | 2018-02-06 | — | — | US | disclosed |
| US-9884830-B2 | Synthesis of tetracyclines and analogues thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2018-02-06 | — | — | US | disclosed |
| WO-2018022944-A1 | BLOCK CO-POLY(METAL ORGANIC NANOSTRUCTURES) (BCPMONs) AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2018-02-01 | — | — | WO | disclosed |
| US-20180030451-A1 | METHODS FOR TREATING AGING AND SKIN DISORDERS USING NUCLEIC ACIDS TARGETING TYR OR MMP1 | RXI PHARMACEUTICALS CORPORATION (US) | 2018-02-01 | — | — | US | disclosed |
| US-20180028664-A1 | COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS | MODERNATX, INC. (US) | 2018-02-01 | — | — | US | disclosed |
| US-20180030213-A1 | BLOCK CO-POLY(METAL ORGANIC NANOSTRUCTURES) (BCPMONS) AND USES THEREOF | MASSACHUSETTS INST TECHNOLOGY (US) | 2018-02-01 | — | — | US | disclosed |
| EP-3273966-A2 | INHIBITORS OF CYCLIN-DEPENDENT KINASES | Dana Farber Cancer Institute, Inc. (US) | 2018-01-31 | — | — | EP | disclosed |
| EP-2970266-B1 | 1-PHENOXY-3-(ALKYLAMINO)-PROPAN-2-OL DERIVATIVES AS CARM1 INHIBITORS AND USES THEREOF | EPIZYME INC (US) | 2018-01-31 | — | — | EP | disclosed |
| EP-3273969-A1 | MACROLIDES WITH MODIFIED DESOSAMINE SUGARS AND USES THEREOF | President and Fellows of Harvard College (US) | 2018-01-31 | — | — | EP | disclosed |
| US-9877942-B1 | Co-crystals of substituted glycine and uses thereof | SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) | 2018-01-30 | — | — | US | disclosed |
| US-9879042-B2 | Human iNKT cell activation using glycolipids | ACADEMIA SINICA (TW) | 2018-01-30 | — | — | US | disclosed |
| US-9878987-B2 | HSP70 modulators and methods for making and using the same | MEMORIAL SLOAN KETTERING CANCER CENTER (US) | 2018-01-30 | — | — | US | disclosed |
| US-9879003-B2 | Host targeted inhibitors of dengue virus and other viruses | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2018-01-30 | — | — | US | disclosed |
| US-9877970-B2 | Therapeutic compounds and uses thereof | KALA PHARMACEUTICALS, INC. (US) | 2018-01-30 | — | — | US | disclosed |
| US-20180021368-A1 | BOLAAMPHIPHILIC COMPOUNDS, COMPOSITIONS AND USES THEREOF | LAUREN SCIENCES LLC (US) | 2018-01-25 | — | — | US | disclosed |
| US-20180022869-A1 | POLYCARBONATE POLYOL COMPOSITIONS AND METHODS | NOVOMER, INC. | 2018-01-25 | — | — | US | disclosed |
| US-9872911-B2 | Alpha-aminoamidine polymers and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2018-01-23 | — | — | US | disclosed |
| US-9873691-B2 | TRPV1 antagonists including dihydroxy substituent and uses thereof | PURDUE PHARMA L.P. (US) | 2018-01-23 | — | — | US | disclosed |
| WO-2018013525-A1 | NUCLEIC ACID CONJUGATES AND USES THEREOF | TRANSLATE BIO MA, INC. (US) | 2018-01-18 | — | — | WO | disclosed |
| EP-3269395-A1 | AMINOALCOHOL LIPIDOIDS AND USES THEREOF | Massachusetts Institute Of Technology (US) | 2018-01-17 | — | — | EP | disclosed |
| US-9868703-B2 | PRMT1 inhibitors and uses thereof | Epizyme, Inc. (US) | 2018-01-16 | — | — | US | disclosed |
| US-20180009847-A1 | PROLINE-LOCKED STAPLED PEPTIDES AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2018-01-11 | — | — | US | disclosed |
| WO-2018009544-A1 | BICYCLIC UREA KINASE INHIBITORS AND USES THEREOF | THE BROAD INSTITUTE, INC. (US) | 2018-01-11 | — | — | WO | disclosed |
| US-20180011104-A1 | REACTIVE LABELLING COMPOUNDS AND USES THEREOF | ACADEMIA SINICA (TW) | 2018-01-11 | — | — | US | disclosed |
| EP-2963012-B1 | ISOPRENYL COMPOUNDS AND METHODS THEREOF | SIGNUM BIOSCIENCES INC (US) | 2018-01-10 | — | — | EP | disclosed |
| US-9862688-B2 | Hydrophobically tagged janus kinase inhibitors and uses thereof | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2018-01-09 | — | — | US | disclosed |
| US-9861634-B2 | Therapeutic compounds and uses thereof | KALA PHARMACEUTICALS, INC. (US) | 2018-01-09 | — | — | US | disclosed |
| US-9861641-B2 | Methods for reducing body fat using tafluprost and analogs thereof | TOPOKINE THERAPEUTICS, INC. (US) | 2018-01-09 | — | — | US | disclosed |
| US-9856267-B2 | CARM1 inhibitors and uses thereof | Epizyme, Inc. (US) | 2018-01-02 | — | — | US | disclosed |
| US-9856225-B2 | Substituted phenazines as antimicrobial agents | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2018-01-02 | — | — | US | disclosed |
| US-9856349-B2 | Catalysts and methods for polymer synthesis | SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) | 2018-01-02 | — | — | US | disclosed |
| US-9856223-B2 | Methods to treat lymphoplasmacytic lymphoma | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2018-01-02 | — | — | US | disclosed |
| CN-107531737-A | Synthesis of desosamine | 哈佛大学的校长及成员们 | 2018-01-02 | — | — | CN | disclosed |
| CN-107530365-A | Macrolide of desosamine sugar with modification and application thereof | 哈佛大学的校长及成员们 | 2018-01-02 | — | — | CN | disclosed |
| CN-107522664-A | The amino acid derivativges of functionalization on N-terminal of drug encapsulation microballoon can be formed | 麻省理工学院 | 2017-12-29 | — | — | CN | disclosed |
| US-20170368011-A1 | ISOPRENYL COMPOUNDS AND METHODS THEREOF | SIGNUM BIOSCIENCES, INC. (US) | 2017-12-28 | — | — | US | disclosed |
| US-9850345-B2 | Polycarbonate polyol compositions and methods | SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) | 2017-12-26 | — | — | US | disclosed |
| US-9849187-B2 | Conjugates of tumor necrosis factor inhibitors to functionalized polymers | QUIAPEG PHARMACEUTICALS AB (SE) | 2017-12-26 | — | — | US | disclosed |
| US-9849179-B2 | Methods for topical delivery of prostaglandins to subcutaneous fat | TOPOKINE THERAPEUTICS, INC. (US) | 2017-12-26 | — | — | US | disclosed |
| US-20170362265-A1 | METHODS FOR MODULAR SYNTHESIS OF N-GLYCANS AND ARRAYS THEREOF | ACADEMIA SINICA (TW) | 2017-12-21 | — | — | US | disclosed |
| US-20170360924-A1 | HUMAN iNKT CELL ACTIVATION USING GLYCOLIPIDS WITH ALTERED GLYCOSYL GROUPS | ACADEMIA SINICA (TW) | 2017-12-21 | — | — | US | disclosed |
| EP-3257887-A1 | POLYCARBONATE POLYOL COMPOSITIONS AND METHODS | SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) | 2017-12-20 | — | — | EP | disclosed |
| US-20170355711-A1 | THIENOPYRIMIDINES AND USES THEREOF | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2017-12-14 | — | — | US | disclosed |
| US-20170355669-A1 | COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS | LANTHEUS MEDICAL IMAGING, INC. (US) | 2017-12-14 | — | — | US | disclosed |
| WO-2017214337-A1 | DRUG DELIVERY POLYMERS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2017-12-14 | — | — | WO | disclosed |
| US-9840479-B2 | Polyamine-fatty acid derived lipidoids and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2017-12-12 | — | — | US | disclosed |
| US-20170349590-A1 | MEROPENEM DERIVATIVES AND USES THEREOF | OXFORD FINANCE LLC | 2017-12-07 | — | — | US | disclosed |
| US-20170348431-A1 | DRUG DELIVERY POLYMERS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2017-12-07 | — | — | US | disclosed |
| US-20170349552-A1 | Treatment of Amyotrophic Lateral Sclerosis | NORTHWESTERN UNIVERSITY (US) | 2017-12-07 | — | — | US | disclosed |
| US-9833453-B2 | Therapeutic compounds and uses thereof | KALA PHARMACEUTICALS, INC. (US) | 2017-12-05 | — | — | US | disclosed |
| CN-103958540-B | Neuroactive steroids, compositions, and uses thereof | 萨奇治疗股份有限公司 | 2017-12-05 | — | — | CN | disclosed |
| CN-107417616-A | Methods and compositions for treating beta-thalassemia and sickle cell disease | 中央研究院 | 2017-12-01 | — | — | CN | disclosed |
| CN-107427521-A | The inhibitor of cell cycle protein dependent kinase | 达纳-法伯癌症研究所股份有限公司 | 2017-12-01 | — | — | CN | disclosed |
| WO-2017205566-A1 | OXIDIZED AMINOLIPIDOIDS AND USES THEREOF | Preceres Inc. (US) | 2017-11-30 | — | — | WO | disclosed |
| US-20170342103-A1 | 3,3 DISUBSTITUTED 19-NOR PREGNANE COMPOUNDS, COMPOSITIONS, AND USES THEREOF | SAGE THERAPEUTICS, INC. | 2017-11-30 | — | — | US | disclosed |
| US-9827248-B2 | Therapeutic compounds and uses thereof | KALA PHARMACEUTICALS, INC. (US) | 2017-11-28 | — | — | US | disclosed |
| CN-104230971-B | Boric acid and ester as inhibitors of fatty amide hydrolase | 英菲尼提制药公司 | 2017-11-24 | — | — | CN | disclosed |
| US-20170334861-A1 | TETRAHYDRO- AND DIHYDRO-ISOQUINOLINE PRMT5 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2017-11-23 | — | — | US | disclosed |
| US-20170333436-A1 | HCK AS A THERAPEUTIC TARGET IN MYD88 MUTATED DISEASES | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2017-11-23 | — | — | US | disclosed |
| WO-2017198775-A1 | STEREOSELECTIVE SYNTHESIS OF PHOSPHOROTHIOATE OLIGORIBONUCLEOTIDES | ETH ZURICH (CH) | 2017-11-23 | — | — | WO | disclosed |
| US-9822140-B2 | Methods and intermediates for the preparation of fondaparinux | ACADEMIA SINICA (TW) | 2017-11-21 | — | — | US | disclosed |
| US-9820993-B2 | Methods and compositions for topical delivery of prostaglandins to subcutaneous fat | TOPOKINE THERAPEUTICS, INC. (US) | 2017-11-21 | — | — | US | disclosed |
| EP-2296581-B1 | A BIOMATERIAL | COLOPLAST AS (DK) | 2017-11-15 | — | — | EP | disclosed |
| EP-2970131-B1 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | EPIZYME INC (US) | 2017-11-15 | — | — | EP | disclosed |
| CN-105189462-B | therapeutic compounds and uses thereof | 卡拉制药公司 | 2017-11-10 | — | — | CN | disclosed |
| US-20170320886-A1 | CORTISTATIN ANALOGUES AND SYNTHESES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2017-11-09 | — | — | US | disclosed |
| US-20170320883-A1 | CARM1 INHIBITORS AND USES THEREOF | Epizyme, Inc. | 2017-11-09 | — | — | US | disclosed |
| WO-2017192679-A1 | METHODS AND COMPOSITIONS OF BIOLOGICALLY ACTIVE AGENTS | WAVE LIFE SCIENCES LTD. (SG) | 2017-11-09 | — | — | WO | disclosed |
| WO-2017192664-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2017-11-09 | — | — | WO | disclosed |
| US-9809678-B2 | Polycarbonate polyol compositions and methods | SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) | 2017-11-07 | — | — | US | disclosed |
| US-9809556-B2 | Treatment of amyotrophic lateral sclerosis | NORTHWESTERN UNIVERSITY (US) | 2017-11-07 | — | — | US | disclosed |
| CN-107311935-A | For synthesizing and using the composition of contrast agent, method and system | 蓝瑟斯医学影像公司 | 2017-11-03 | — | — | CN | disclosed |
| CN-104136419-B | amino acid derivatives functionalized at the N-terminus capable of forming drug-encapsulated microspheres | 麻省理工学院 | 2017-11-03 | — | — | CN | disclosed |
| WO-2017190061-A1 | SYNTHETIC DNA BINDING DOMAIN PEPTIDES AND USES THEREOF | THE UNIVERSITY OF CHICAGO (US) | 2017-11-02 | — | — | WO | disclosed |
| WO-2017190038-A1 | ANALOGS OF YOHIMBINE AND USES THEREOF | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2017-11-02 | — | — | WO | disclosed |
| US-20170312363-A1 | MULTIFUNCTIONALIZED POLYETHYLENE GLYCOL DERIVATIVE AND PREPARATION METHOD THEREFOR | XIAMEN SINOPEG BIOTECH CO., LTD. (CN) | 2017-11-02 | — | — | US | disclosed |
| US-20170313736-A1 | MUTAGENIC NUCLEOSIDE ANALOGS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2017-11-02 | — | — | US | disclosed |
| WO-2017189999-A1 | HCK AS A THERAPEUTIC TARGET IN MYD88 MUTATED DISEASES | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2017-11-02 | — | — | WO | disclosed |
| EP-3236959-A2 | INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 (CDK7) | Dana Farber Cancer Institute, Inc. (US) | 2017-11-01 | — | — | EP | disclosed |
| US-9802922-B2 | Urea derivatives and uses thereof | KALA PHARMACEUTICALS, INC. (US) | 2017-10-31 | — | — | US | disclosed |
| US-20170305953-A1 | 14-MEMBERED KETOLIDES AND METHODS OF THEIR PREPARATION AND USE | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2017-10-26 | — | — | US | disclosed |
| WO-2017184999-A1 | EZH2 INHIBITORS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2017-10-26 | — | — | WO | disclosed |
| CN-107266670-A | Polycarbonate polyol composition and method | 诺沃梅尔公司 | 2017-10-20 | — | — | CN | disclosed |
| CN-107266669-A | Polycarbonate polyol composition and method | 诺沃梅尔公司 | 2017-10-20 | — | — | CN | disclosed |
| US-20170298402-A1 | SELF-LABELING NUCLEIC ACIDS AND METHODS OF USE | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2017-10-19 | — | — | US | disclosed |
| EP-3230279-A1 | FUSED 1,3-AZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF PROLIFERATIVE DISEASES | Massachusetts Institute of Technology (US) | 2017-10-18 | — | — | EP | disclosed |
| US-9790188-B2 | Benzimidazole derivatives and uses thereof | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2017-10-17 | — | — | US | disclosed |
| US-9790324-B2 | Functionalized polymers | QUIAPEG AB | 2017-10-17 | — | — | US | disclosed |
| US-20170290820-A1 | METHODS AND COMPOSITIONS FOR TREATING BETA-THALASSEMIA AND SICKLE CELL DISEASE | ACADEMIA SINICA (TW) | 2017-10-12 | — | — | US | disclosed |
| US-20170291905-A1 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2017-10-12 | — | — | US | disclosed |
| EP-3226848-A1 | METHODS FOR THE TREATMENT OF ALOPECIA AREATA UTILIZING GENE MODULATION APPROACHES | RXi Pharmaceuticals Corporation (US) | 2017-10-11 | — | — | EP | disclosed |
| US-9782476-B2 | Human iNKT cell activation using glycolipids with altered glycosyl groups | ACADEMIA SINICA (TW) | 2017-10-10 | — | — | US | disclosed |
| US-20170280720-A1 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2017-10-05 | — | — | US | disclosed |
| US-20170283440-A1 | CARM1 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2017-10-05 | — | — | US | disclosed |
| US-20170283450-A1 | TRITERPENE SAPONINS, METHODS OF SYNTHESIS AND USES THEREOF | MEMORIAL SLOAN-KETTERING INST FOR CANCER RES (US) | 2017-10-05 | — | — | US | disclosed |
| US-20170281542-A1 | LIPID FORMULATIONS FOR DELIVERY OF MESSENGER RNA | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2017-10-05 | — | — | US | disclosed |
| US-9777008-B2 | PRMT5 inhibitors and uses thereof | Epizyme, Inc. (US) | 2017-10-03 | — | — | US | disclosed |
| US-9776972-B2 | Pyrazole derivatives as arginine methyltransferase inhibitors and uses thereof | EPIZYME INC. (US) | 2017-10-03 | — | — | US | disclosed |
| US-9775915-B2 | Trioxacarcins, trioxacarcin-antibody conjugates, and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2017-10-03 | — | — | US | disclosed |
| US-20170275621-A1 | CHIRAL CONTROL | WAVE LIFE SCIENCES USA, INC. | 2017-09-28 | — | — | US | disclosed |
| EP-2512574-B1 | A UROLOGICAL DEVICE | COLOPLAST AS (DK) | 2017-09-27 | — | — | EP | disclosed |
| EP-3221299-A1 | 2-THIOXOTHIAZOLIDIN-4-ONE DERIVATIVES ACTIVE AS TRANSTHYRETIN LIGANDS AND USES THEREOF | BSIM2 Biomolecular Simulations Lda. (PT) | 2017-09-27 | — | — | EP | disclosed |
| US-20170267642-A1 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2017-09-21 | — | — | US | disclosed |
| US-20170266161-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR MAKING THE SAME | SIGNUM BIOSCIENCES, INC. (US) | 2017-09-21 | — | — | US | disclosed |
| WO-2017158168-A1 | INHIBITORS OF TALIN-VINCULIN BINDING FOR THE TREATMENT OF CANCER | FUNDACIÓ INSTITUT DE BIOENGINYERIA DE CATALUNYA (IBEC) (ES) | 2017-09-21 | — | — | WO | disclosed |
| US-20170266326-A1 | COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS | LANTHEUS MEDICAL IMAGING, INC. (US) | 2017-09-21 | — | — | US | disclosed |
| WO-2017157990-A1 | PEPTIDES WITH ANTI-CANCER ACTIVITY | IDP DISCOVERY PHARMA, S.L. (ES) | 2017-09-21 | — | — | WO | disclosed |
| US-9765035-B2 | Arginine methyltransferase inhibitors and uses thereof | Epizyme, Inc. (US) | 2017-09-19 | — | — | US | disclosed |
| US-9765068-B2 | PRMT5 inhibitors and uses thereof | Epizyme, Inc. (US) | 2017-09-19 | — | — | US | disclosed |
| WO-2017156192-A1 | METHODS FOR MODULAR SYNTHESIS OF N-GLYCANS AND ARRAYS THEREOF | ACADEMIA SINICA (TW) | 2017-09-14 | — | — | WO | disclosed |
| WO-2017156265-A1 | DIRECT PALLADIUM-CATALYZED AROMATIC FLUORINATION | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2017-09-14 | — | — | WO | disclosed |
| EP-3215160-A1 | USE OF COMPOSITIONS MODULATING CHROMATIN STRUCTURE FOR GRAFT VERSUS HOST DISEASE (GVHD) | Dana-Farber Cancer Institute, Inc. (US) | 2017-09-13 | — | — | EP | disclosed |
| EP-3214935-A1 | EZH2 INHIBITORS AND USES THEREOF | Dana-Farber Cancer Institute, Inc. (US) | 2017-09-13 | — | — | EP | disclosed |
| US-9758522-B2 | Hydrophobically tagged small molecules as inducers of protein degradation | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2017-09-12 | — | — | US | disclosed |
| US-9759726-B2 | Reactive labelling compounds and uses thereof | ACADEMIA SINICA (TW) | 2017-09-12 | — | — | US | disclosed |
| CN-105452226-B | Tetrahydro-and dihydro-isoquinoline PRMT5 inhibitors and uses thereof | EPIZYME股份有限公司 | 2017-09-12 | — | — | CN | disclosed |
| EP-3211997-A1 | 14-MEMBERED KETOLIDES AND METHODS OF THEIR PREPARATION AND USE | President and Fellows of Harvard College (US) | 2017-09-06 | — | — | EP | disclosed |
| WO-2017059411-A9 | INHIBITORS OF MENAQUINONE BIOSYNTHESIS | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2017-08-31 | — | — | WO | disclosed |
| US-20170246319-A1 | BIODEGRADABLE LIPIDS FOR DELIVERY OF NUCLEIC ACIDS | SHIRE HUMAN GENETIC THERAPIES, INC. | 2017-08-31 | — | — | US | disclosed |
| EP-3008081-B1 | STABILIZED POLYPEPTIDE INSULIN RECEPTOR MODULATORS | HARVARD COLLEGE (US) | 2017-08-30 | — | — | EP | disclosed |
| EP-3209648-A1 | THIAZOLYL-CONTAINING COMPOUNDS FOR TREATING PROLIFERATIVE DISEASES | Dana-Farber Cancer Institute, Inc. (US) | 2017-08-30 | — | — | EP | disclosed |
| US-9745355-B2 | Binding-site modified lectins and uses thereof | SMARTCELLS, INC. (US) | 2017-08-29 | — | — | US | disclosed |
| US-9745291-B2 | PRMT5 inhibitors containing a dihydro- or tetrahydroisoquinoline and uses thereof | Epizyme, Inc. (US) | 2017-08-29 | — | — | US | disclosed |
| US-9744147-B2 | Isoprenyl compounds and methods thereof | SIGNUM BIOSCIENCES, INC. (US) | 2017-08-29 | — | — | US | disclosed |
| WO-2017143230-A1 | ANTIFUNGAL COMPOUNDS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2017-08-24 | — | — | WO | disclosed |
| WO-2017143059-A1 | MAX BINDERS AS MYC MODULATORS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2017-08-24 | — | — | WO | disclosed |
| US-20170240537-A1 | PRMT5 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2017-08-24 | — | — | US | disclosed |
| EP-2852678-B1 | TRAPPING REAGENTS FOR REACTIVE METABOLITES SCREENING | BIOGEN MA INC (US) | 2017-08-23 | — | — | EP | disclosed |
| US-9738651-B2 | CARM1 inhibitors and uses thereof | Epizyme, Inc. (US) | 2017-08-22 | — | — | US | disclosed |
| US-9738610-B2 | Indazole derivatives and uses thereof | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2017-08-22 | — | — | US | disclosed |
| CN-107073294-A | Methods of treating aging and skin conditions using nucleic acids targeting TYR or MMP1 | 阿克赛医药公司 | 2017-08-18 | — | — | CN | disclosed |
| WO-2017139414-A1 | INHIBITOR OF INDOLEAMINE-2,3-DIOXYGENASE (IDO) | INVENTISBIO INC. (KY) | 2017-08-17 | — | — | WO | disclosed |
| US-20170233352-A1 | HSP70 MODULATORS AND METHODS FOR MAKING AND USING THE SAME | MEMORIAL SLOAN KETTERING CANCER CENTER | 2017-08-17 | — | — | US | disclosed |
| US-20170233405-A1 | MAX BINDERS AS MYC MODULATORS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2017-08-17 | — | — | US | disclosed |
| US-20170233347-A1 | PRMT1 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2017-08-17 | — | — | US | disclosed |
| US-20170233411-A1 | THIAZOLYL-CONTAINING COMPOUNDS FOR TREATING PROLIFERATIVE DISEASES | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2017-08-17 | — | — | US | disclosed |
| EP-2831079-B1 | BICYCLIC HETEROCYCLIC DERIVATIVES AS MNK1 AND MNK2 MODULATORS AND USES THEREOF | AGENCY SCIENCE TECH & RES (SG) | 2017-08-16 | — | — | EP | disclosed |
| EP-2646411-B1 | PREPARATION OF PET PRECURSOR | BLUE EARTH DIAGNOSTICS LTD (GB) | 2017-08-16 | — | — | EP | disclosed |
| US-9732041-B2 | Arginine methyltransferase inhibitors and uses thereof | Epizyme, Inc. (US) | 2017-08-15 | — | — | US | disclosed |
| US-9732072-B2 | PRMT5 inhibitors and uses thereof | Epizyme, Inc. (US) | 2017-08-15 | — | — | US | disclosed |
| CN-107033164-A | Prepare the synthetic method of ecteinascidin compounds | 法马马有限公司 | 2017-08-11 | — | — | CN | disclosed |
| WO-2017136688-A1 | SELECTIVE ESTROGEN RECEPTOR DEGRADERS AND USES THEREOF | INVENTISBIO INC. (KY) | 2017-08-10 | — | — | WO | disclosed |
| WO-2017136689-A1 | PURINE COMPOUNDS POSSESSING ANTICANCER ACTIVITY | ACADEMIA SINICA (TW) | 2017-08-10 | — | — | WO | disclosed |
| US-20170224700-A1 | USES OF SALT-INDUCIBLE KINASE (SIK) INHIBITORS | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2017-08-10 | — | — | US | disclosed |
| US-9725451-B2 | Meropenem derivatives and uses thereof | KALA PHARMACEUTICALS, INC. (US) | 2017-08-08 | — | — | US | disclosed |
| US-9724682-B2 | Synthesis of acyclic and cyclic amines using iron-catalyzed nitrene group transfer | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2017-08-08 | — | — | US | disclosed |
| US-9724332-B2 | Arginine methyltransferase inhibitors and uses thereof | Epizyme, Inc. (US) | 2017-08-08 | — | — | US | disclosed |
| US-9725425-B1 | Compounds and methods for treating cancer | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2017-08-08 | — | — | US | disclosed |
| WO-2017132103-A2 | PHOSPHONATE LINKERS AND THEIR USE TO FACILITATE CELLULAR RETENTION OF COMPOUNDS | MERCK SHARP & DOHME CORP. (US) | 2017-08-03 | — | — | WO | disclosed |
| EP-2337809-B1 | POLYCARBONATE POLYOL COMPOSITIONS AND METHODS | NOVOMER INC (US) | 2017-08-02 | — | — | EP | disclosed |
| US-9718816-B2 | 1-phenoxy-3-(alkylamino)-propan-2-ol derivatives as CARM1 inhibitors and uses thereof | Epizyme, Inc. (US) | 2017-08-01 | — | — | US | disclosed |
| US-9718850-B2 | Triterpene saponins, methods of synthesis and uses thereof | MEMORIAL SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2017-08-01 | — | — | US | disclosed |
| CN-106998685-A | 14-membered ketolides and methods of making and using the same | 哈佛大学的校长及成员们 | 2017-08-01 | — | — | CN | disclosed |
| WO-2017127528-A1 | PEPTOID AGONISTS OF FIBROBLAST GROWTH RECEPTORS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2017-07-27 | — | — | WO | disclosed |
| US-20170209420-A1 | USES OF 4'-DESFERRITHIOCIN ANALOGS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2017-07-27 | — | — | US | disclosed |
| US-20170210751-A1 | PRMT5 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2017-07-27 | — | — | US | disclosed |
| EP-2705039-B1 | BROMODOMAIN INHIBITORS AND USES THEREOF | CONSTELLATION PHARMACEUTICALS INC (US) | 2017-07-26 | — | — | EP | disclosed |
| US-9714946-B2 | Bromodomain binding reagents and uses thereof | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2017-07-25 | — | — | US | disclosed |
| US-9714255-B2 | Cortistatin analogues and syntheses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2017-07-25 | — | — | US | disclosed |
| US-9714265-B2 | Mutagenic nucleoside analogs and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2017-07-25 | — | — | US | disclosed |
| US-9713651-B2 | Compositions, methods, and systems for the synthesis and use of imaging agents | LANTHEUS MEDICAL IMAGING, INC. (US) | 2017-07-25 | — | — | US | disclosed |
| CN-106977429-A | Composition, method and system for synthesizing and using contrast agent | 蓝瑟斯医学影像公司 | 2017-07-25 | — | — | CN | disclosed |
| CN-106963514-A | Urinary device | 科洛普拉斯特公司 | 2017-07-21 | — | — | CN | disclosed |
| US-20170204082-A1 | IMIDAZOLYL KINASE INHIBITORS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2017-07-20 | — | — | US | disclosed |
| US-20170204116-A1 | MACROCYCLIC KINASE INHIBITORS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2017-07-20 | — | — | US | disclosed |
| US-20170202984-A1 | COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS | LANTHEUS MEDICAL IMAGING, INC. (US) | 2017-07-20 | — | — | US | disclosed |
| US-20170202852-A1 | TOPICAL DOSAGE REGIMEN | TOPOKINE THERAPEUTICS, INC. (US) | 2017-07-20 | — | — | US | disclosed |
| US-20170204075-A1 | AMINOALCOHOL LIPIDOIDS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2017-07-20 | — | — | US | disclosed |
| US-20170202810-A1 | SMALL MOLECULE INHIBITORS OF USP1 DEUBIQUITINATING ENZYME ACTIVITY | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2017-07-20 | — | — | US | disclosed |
| WO-2017124087-A1 | ANTI-PARASITIC COMPOUNDS AND USES THEREOF | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2017-07-20 | — | — | WO | disclosed |
| EP-2550285-B1 | TRIOXACARCINS AND USES THEREOF | HARVARD COLLEGE (US) | 2017-07-19 | — | — | EP | disclosed |
| EP-3191500-A2 | HUMAN iNKT CELL ACTIVATION USING GLYCOLIPIDS | Academia Sinica (TW) | 2017-07-19 | — | — | EP | disclosed |
| US-20170199201-A2 | SURROGATES OF POST-TRANSLATIONALLY MODIFIED PROTEINS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2017-07-13 | — | — | US | disclosed |
| US-20170198006-A1 | PRMT5 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2017-07-13 | — | — | US | disclosed |
| US-20170196675-A1 | UROLOGICAL DEVICE HAVING A BLADDER RETAINER AND A VALVE | COLOPLAST A/S (DK) | 2017-07-13 | — | — | US | disclosed |
| EP-3188799-A2 | METHODS FOR TREATING AGING AND SKIN DISORDERS USING NUCLEIC ACIDS TARGETING TYR OR MMP1 | RXi Pharmaceuticals Corporation (US) | 2017-07-12 | — | — | EP | disclosed |
| EP-2365962-B1 | AMINOALCOHOL LIPIDOIDS AND USES THEREOF | MASSACHUSETTS INST TECHNOLOGY (US) | 2017-07-05 | — | — | EP | disclosed |
| US-9695172-B2 | Diazepane derivatives and uses thereof | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2017-07-04 | — | — | US | disclosed |
| US-9695156-B2 | Compounds for the treatment and prevention of infections | BROWN UNIVERSITY (US) | 2017-07-04 | — | — | US | disclosed |
| US-9695184-B2 | Therapeutic compounds and uses thereof | KALA PHARMACEUTICALS, INC. (US) | 2017-07-04 | — | — | US | disclosed |
| US-20170183378-A1 | TRAPPING REAGENTS FOR REACTIVE METABOLITES SCREENING | BIOGEN MA INC. (US) | 2017-06-29 | — | — | US | disclosed |
| US-20170182181-A1 | PHOSPHATE BASED LINKERS FOR INTRACELLULAR DELIVERY OF DRUG CONJUGATES | MERCK SHARP & DOHME CORP. (US) | 2017-06-29 | — | — | US | disclosed |
| WO-2017112852-A1 | MODIFIED POLYETHYLENEIMINES AND USES THEREOF | Preceres Inc. (US) | 2017-06-29 | — | — | WO | disclosed |
| WO-2017112823-A1 | TARGETED SELECTION OF PATIENTS FOR TREATMENT WITH SPECIFIC CORTISTATIN DERIVATIVES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2017-06-29 | — | — | WO | disclosed |
| US-20170182005-A1 | PRMT1 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2017-06-29 | — | — | US | disclosed |
| US-20170183369-A1 | CATALYSTS AND METHODS FOR POLYMER SYNTHESIS | SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) | 2017-06-29 | — | — | US | disclosed |
| US-20170183447-A1 | METHODS FOR POLYMER SYNTHESIS | NOVOMER, INC. | 2017-06-29 | — | — | US | disclosed |
| US-9688644-B2 | Synthesis of Tetracyclines and intermediates thereto | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2017-06-27 | — | — | US | disclosed |
| WO-2017106836-A1 | TRITERPENE SAPONIN VARIANTS, METHODS OF SYNTHESIS AND USE THEREOF | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2017-06-22 | — | — | WO | disclosed |
| US-9682927-B2 | Compositions, methods, and systems for the synthesis and use of imaging agents | LANTHEUS MEDICAL IMAGING, INC. (US) | 2017-06-20 | — | — | US | disclosed |
| WO-2017099823-A1 | COMPOSITIONS AND METHODS FOR DELIVERY OF THERAPEUTIC AGENTS | MODERNATX, INC. (US) | 2017-06-15 | — | — | WO | disclosed |
| WO-2017100744-A1 | AMINOLIPIDOIDS AND USES THEREOF | Preceres Inc. (US) | 2017-06-15 | — | — | WO | disclosed |
| WO-2017100350-A1 | MULTIPLEXING IN PARTITIONS USING MICROPARTICLES | RAINDANCE TECHNOLOGIES, INC. (US) | 2017-06-15 | — | — | WO | disclosed |
| US-20170165290-A1 | AMINO ACID-, PEPTIDE- AND POLYPEPTIDE-LIPIDS, ISOMERS, COMPOSITIONS, AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2017-06-15 | — | — | US | disclosed |
| US-20170166558-A1 | O-GLCNAC TRANSFERASE (OGT) INHIBITORS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2017-06-15 | — | — | US | disclosed |
| EP-3177147-A1 | DIHYDROPTERIDINONE DERIVATIVES AND USES THEREOF | Dana-Farber Cancer Institute, Inc. (US) | 2017-06-14 | — | — | EP | disclosed |
| EP-3177626-A1 | DIAZEPANE DERIVATIVES AND USES THEREOF | Dana Farber Cancer Institute, Inc. (US) | 2017-06-14 | — | — | EP | disclosed |
| EP-3177295-A2 | USES OF SALT-INDUCIBLE KINASE (SIK) INHIBITORS | Dana Farber Cancer Institute, Inc. (US) | 2017-06-14 | — | — | EP | disclosed |
| US-9675614-B2 | PRMT5 inhibitors and uses thereof | Epizyme, Inc. (US) | 2017-06-13 | — | — | US | disclosed |
| WO-2017095950-A2 | COMPOUNDS FOR TREATING PROLIFERATIVE DISEASES | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2017-06-08 | — | — | WO | disclosed |
| EP-2970181-B1 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | EPIZYME INC (US) | 2017-06-07 | — | — | EP | disclosed |
| WO-2017091673-A2 | BIVALENT BROMODOMAIN INHIBTORS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2017-06-01 | — | — | WO | disclosed |
| US-20170151353-A9 | COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS | LANTHEUS MEDICAL IMAGING, INC. (US) | 2017-06-01 | — | — | US | disclosed |
| EP-3171874-A1 | IMIDAZOLYL KINASE INHIBITORS AND USES THEREOF | Dana-Farber Cancer Institute, Inc. (US) | 2017-05-31 | — | — | EP | disclosed |
| EP-3172213-A1 | MACROCYCLIC KINASE INHIBITORS AND USES THEREOF | Dana Farber Cancer Institute, Inc. (US) | 2017-05-31 | — | — | EP | disclosed |
| US-9662324-B2 | Methods and compositions for treating β-thalassemia and sickle cell disease | ACADEMIA SINICA (TW) | 2017-05-30 | — | — | US | disclosed |
| US-20170145023-A1 | DIAZEPANE DERIVATIVES AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2017-05-25 | — | — | US | disclosed |
| US-20170145013-A1 | DIHYDROPTERIDINONE DERIVATIVES AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2017-05-25 | — | — | US | disclosed |
| US-20170137437-A1 | SYNTHESIS OF HALICHONDRIN ANALOGS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2017-05-18 | — | — | US | disclosed |
| US-20170136032-A1 | METHODS AND COMPOSITIONS FOR TREATING METABOLIC SYNDROME | TOPOKINE THERAPEUTICS, INC. (US) | 2017-05-18 | — | — | US | disclosed |
| WO-2017079582-A1 | TRITERPENE SAPONIN ANALOGUES | ADJUVANCE TECHNOLOGIES, INC. (US) | 2017-05-11 | — | — | WO | disclosed |
| WO-2017079609-A1 | POLYAMINE SULFONAMIDES AND USES THEREOF | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2017-05-11 | — | — | WO | disclosed |
| US-20170129876-A1 | UREA DERIVATIVES AND USES THEREOF | KALA BIO, Inc. | 2017-05-11 | — | — | US | disclosed |
| EP-3164379-A1 | POLYAMINE-FATTY ACID DERIVED LIPIDOIDS AND USES THEREOF | Massachusetts Institute of Technology (US) | 2017-05-10 | — | — | EP | disclosed |
| CN-106659731-A | Topical compositions and methods for treating wounds | 夏尔人类遗传性治疗公司 | 2017-05-10 | — | — | CN | disclosed |
| US-20170119735-A1 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2017-05-04 | — | — | US | disclosed |
| EP-3160970-A1 | SYNTHESIS OF HALICHONDRIN ANALOGS AND USES THEREOF | President and Fellows of Harvard College (US) | 2017-05-03 | — | — | EP | disclosed |
| EP-3160466-A2 | PRMT5 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2017-05-03 | — | — | EP | disclosed |
| EP-3160477-A2 | PRMT5 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2017-05-03 | — | — | EP | disclosed |
| WO-2017070151-A1 | REDUCED SIZE SELF-DELIVERING NUCLEIC ACID COMPOUNDS TARGETING LONG NON-CODING RNA | RXI PHARMACEUTICALS CORPORATION (US) | 2017-04-27 | — | — | WO | disclosed |
| WO-2017068577-A1 | PEPTIDE-BASED MULTIPLE-DRUG DELIVERY VEHICLE | ARIEL-UNIVERSITY RESEARCH AND DEVELOPMENT COMPANY LTD. (IL) | 2017-04-27 | — | — | WO | disclosed |
| US-20170114323-A1 | USES OF KINASE INHIBITORS FOR INDUCING AND MAINTAINING PLURIPOTENCY | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2017-04-27 | — | — | US | disclosed |
| US-20170114061-A1 | PRMT5 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2017-04-27 | — | — | US | disclosed |
| EP-3159352-A1 | STITCHED POLYPEPTIDES | President and Fellows of Harvard College (US) | 2017-04-26 | — | — | EP | disclosed |
| CN-103282073-B | Urinary device | 科洛普拉斯特公司 | 2017-04-26 | — | — | CN | disclosed |
| US-9629804-B2 | Lipid formulations for delivery of messenger RNA | SHIRE HUMAN GENETIC THERAPIES, INC. (US) | 2017-04-25 | — | — | US | disclosed |
| US-9630961-B2 | Arginine methyltransferase inhibitors and uses thereof | Epizyme, Inc. (US) | 2017-04-25 | — | — | US | disclosed |
| CN-106573951-A | Micro saponin analogue, synthesis and use thereof | 索隆-基特林癌症研究协会 | 2017-04-19 | — | — | CN | disclosed |
| WO-2017062862-A2 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2017-04-13 | — | — | WO | disclosed |
| WO-2017062622-A1 | SUPRAMOLECULAR MODIFICATION OF PROTEINS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2017-04-13 | — | — | WO | disclosed |
| EP-3153135-A1 | A GASTROINTESTINAL IMPLANT DEVICE | Coloplast A/S (DK) | 2017-04-12 | — | — | EP | disclosed |
| US-9617212-B2 | Isoindolin-1-ones as macrophage migration inhibitory factor (MIF) inhibitors | CONTROLLED CHEMICALS, INC. (US) | 2017-04-11 | — | — | US | disclosed |
| US-9617309-B2 | Proline-locked stapled peptides and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2017-04-11 | — | — | US | disclosed |
| US-20170096444-A1 | MINIMAL SAPONIN ANALOGUES, SYNTHESIS AND USE THEREOF | MEMORIAL SLOAN-KETTERING CANCER CENTER | 2017-04-06 | — | — | US | disclosed |
| EP-3149015-A1 | MINIMAL SAPONIN ANALOGUES, SYNTHESIS AND USE THEREOF | Memorial Sloan-Kettering Cancer Center (US) | 2017-04-05 | — | — | EP | disclosed |
| EP-2391714-B1 | METHODS FOR LIGATION AND USES THEREOF | WHITEHEAD INST BIOMEDICAL RES (US) | 2017-04-05 | — | — | EP | disclosed |
| EP-3148552-A2 | BIODEGRADABLE LIPIDS FOR DELIVERY OF NUCLEIC ACIDS | Shire Human Genetic Therapies, Inc. (US) | 2017-04-05 | — | — | EP | disclosed |
| US-9611287-B2 | Trioxacarcins and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2017-04-04 | — | — | US | disclosed |
| US-9611257-B2 | PRMT5 inhibitors and uses thereof | Epizyme, Inc. (US) | 2017-04-04 | — | — | US | disclosed |
| US-9610322-B2 | Macrocyclic insulin-degrading enzyme (IDE) inhibitors and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2017-04-04 | — | — | US | disclosed |
| WO-2017053696-A2 | HALOGENATED QUINOLINE DERIVATIVES AS ANTIMICROBIAL AGENTS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2017-03-30 | — | — | WO | disclosed |
| US-20170088529-A1 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2017-03-30 | — | — | US | disclosed |
| US-20170088541-A1 | PRMT5 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2017-03-30 | — | — | US | disclosed |
| US-9604930-B2 | Tetrahydro- and dihydro-isoquinoline PRMT5 inhibitors and uses thereof | Epizyme, Inc. (US) | 2017-03-28 | — | — | US | disclosed |
| US-20170081308-A1 | SYNTHESIS OF THIOHYDANTOINS | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2017-03-23 | — | — | US | disclosed |
| EP-3144299-A1 | PYRIMIDINE-2,4,6-TRIONES FOR USE IN THE TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS | Cambria Pharmaceuticals, Inc. (US) | 2017-03-22 | — | — | EP | disclosed |
| EP-3143013-A1 | HSP70 MODULATORS AND METHODS FOR MAKING AND USING THE SAME | Memorial Sloan Kettering Cancer Center (US) | 2017-03-22 | — | — | EP | disclosed |
| US-9598466-B2 | Glycopeptide constructs and uses thereof | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2017-03-21 | — | — | US | disclosed |
| US-9598374-B2 | Arginine methyltransferase inhibitors and uses thereof | Epizyme, Inc. (US) | 2017-03-21 | — | — | US | disclosed |
| WO-2017044858-A2 | INHIBITORS OF CYCLIN-DEPENDENT KINASES | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2017-03-16 | — | — | WO | disclosed |
| WO-2017044792-A1 | ACETAMIDE THIENOTRIAZOLDIAZEPINES AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2017-03-16 | — | — | WO | disclosed |
| WO-2017044849-A1 | CYANO THIENOTRIAZOLODIAZEPINES AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2017-03-16 | — | — | WO | disclosed |
| US-20170072390-A1 | SYNTHESIS OF ACYCLIC AND CYCLIC AMINES USING IRON-CATALYZED NITRENE GROUP TRANSFER | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2017-03-16 | — | — | US | disclosed |
| US-20170073311-A1 | SUPRAMETALLOGELS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2017-03-16 | — | — | US | disclosed |
| US-9593069-B2 | Cyclohexane-1,3-diones for use in the treatment of amyotrophic lateral sclerosis | NORTHWESTERN UNIVERSITY (US) | 2017-03-14 | — | — | US | disclosed |
| US-20170066799-A1 | STITCHED POLYPEPTIDES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2017-03-09 | — | — | US | disclosed |
| US-20170066797-A1 | WITHAFERIN A ANALOGS AND USES THEREOF | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2017-03-09 | — | — | US | disclosed |
| US-20170067056-A1 | RNA INTERFERENCE IN DERMAL AND FIBROTIC INDICATIONS | RXI PHARMACEUTICALS CORPORATION (US) | 2017-03-09 | — | — | US | disclosed |
| WO-2017040653-A1 | HBED PRODRUGS AND USE THEREOF | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPPORATED (US) | 2017-03-09 | — | — | WO | disclosed |
| WO-2017040304-A1 | MALT1 INHIBITORS AND USES THEREOF | CORNELL UNIVERSITY (US) | 2017-03-09 | — | — | WO | disclosed |
| EP-3137118-A1 | METHODS FOR TREATMENT OF DISORDERS IN THE FRONT OF THE EYE UTILIZING NUCLEIC ACID MOLECULES | RXi Pharmaceuticals Corporation (US) | 2017-03-08 | — | — | EP | disclosed |
| EP-3137119-A2 | METHODS FOR TREATING CANCER USING NUCLEIC TARGETING MDM2 OR MYCN | RXi Pharmaceuticals Corporation (US) | 2017-03-08 | — | — | EP | disclosed |
| EP-3138831-A1 | SYNTHESIS OF TETRACYCLINES AND ANALOGUES THEREOF | President and Fellows of Harvard College (US) | 2017-03-08 | — | — | EP | disclosed |
| US-9585740-B2 | Urological device | COLOPLAST A/S (DE) | 2017-03-07 | — | — | US | disclosed |
| US-20170057926-A1 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2017-03-02 | — | — | US | disclosed |
| US-20170056409-A1 | CARM1 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2017-03-02 | — | — | US | disclosed |
| US-9579391-B2 | Conjugate based systems for controlled drug delivery | SMARTCELLS, INC. (US) | 2017-02-28 | — | — | US | disclosed |
| US-9581605-B2 | Trapping reagents for reactive metabolites screening | BIOGEN MA INC. (US) | 2017-02-28 | — | — | US | disclosed |
| US-9580547-B2 | Catalysts and methods for polymer synthesis | NOVOMER, INC. (US) | 2017-02-28 | — | — | US | disclosed |
| US-9580421-B2 | Urea derivatives and uses thereof | KALA PHARMACEUTICALS, INC. (US) | 2017-02-28 | — | — | US | disclosed |
| US-20170051290-A1 | METHODS FOR TREATMENT OF DISORDERS IN THE FRONT OF THE EYE UTILIZING NUCLEIC ACID MOLECULES | RXI PHARMACEUTICALS CORPORATION (US) | 2017-02-23 | — | — | US | disclosed |
| US-20170051106-A1 | POLYCARBONATE POLYOL COMPOSITIONS AND METHODS | SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) | 2017-02-23 | — | — | US | disclosed |
| US-20170049841-A1 | USE OF ANTI-BACTERIAL AGENTS FOR THE TREATMENT OF EPITHELIAL-RELATED CONDITIONS | SIGNUM DERMALOGIX, INC. | 2017-02-23 | — | — | US | disclosed |
| US-20170051288-A1 | METHODS FOR TREATING CANCER USING NUCLEIC ACIDS TARGETING MDM2 OR MYCN | RXI PHARMACEUTICALS CORPORATION (US) | 2017-02-23 | — | — | US | disclosed |
| US-9573911-B2 | Diphosphate mimetics and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2017-02-21 | — | — | US | disclosed |
| WO-2017027841-A1 | PHENYLSULFONAMIDO-BENZOFURAN DERIVATIVES AND USES THEREOF IN THE TREATMENT OF PROLIFERATIVE DISEASES | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2017-02-16 | — | — | WO | disclosed |
| US-20170044111-A1 | JANUS KINASE INHIBITORS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2017-02-16 | — | — | US | disclosed |
| WO-2016134145-A9 | ARTIFICIAL SELF-SUFFICIENT CYTOCHROME P450S | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2017-02-16 | — | — | WO | disclosed |
| WO-2017027845-A1 | PHENYLSULFONAMIDO-BENZOFURAN DERIVATIVES AND USES THEREOF IN THE TREATMENT OF PROLIFERATIVE DISEASES | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2017-02-16 | — | — | WO | disclosed |
| US-20170044112-A1 | HYDROPHOBICALLY TAGGED JANUS KINASE INHIBITORS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2017-02-16 | — | — | US | disclosed |
| EP-2655321-B1 | PURIFICATION OF PRECURSOR COMPOUND BY CRYSTALLISATION | GE HEALTHCARE LTD (GB) | 2017-02-15 | — | — | EP | disclosed |
| EP-3129767-A1 | REACTIVE LABELLING COMPOUNDS AND USES THEREOF | Academia Sinica (TW) | 2017-02-15 | — | — | EP | disclosed |
| US-9567301-B2 | Pyrrol-1-yl benzoic acid derivatives useful as myc inhibitors | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2017-02-14 | — | — | US | disclosed |
| US-20170037399-A1 | CHIRAL DESIGN | WAVE LIFE SCIENCES LTD. (SG) | 2017-02-09 | — | — | US | disclosed |
| EP-3125943-A1 | PHOSPHATE BASED LINKERS FOR INTRACELLULAR DELIVERY OF DRUG CONJUGATES | Merck Sharp & Dohme Corp. (US) | 2017-02-08 | — | — | EP | disclosed |
| US-20170027935-A1 | PRMT5 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2017-02-02 | — | — | US | disclosed |
| WO-2017019949-A1 | MODULAR COMPOSITIONS FOR SCAVENGING SOLUBLE BIOMOLECULES AND METHODS RELATED THERETO | NTERCEPT, LLC (US) | 2017-02-02 | — | — | WO | disclosed |
| US-20170029435-A1 | CORTISTATIN ANALOGUES AND SYNTHESES AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2017-02-02 | — | — | US | disclosed |
| EP-3124015-A1 | COMPOSITIONS AND METHODS FOR TOPICAL DELIVERY OF PROSTAGLANDINS TO SUBCUTANEOUS FAT | Topokine Therapeutics, Inc. (US) | 2017-02-01 | — | — | EP | disclosed |
| US-9555138-B2 | — | — | 2017-01-31 | — | — | US | disclosed |
| US-9556110-B2 | Aminoalcohol lipidoids and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2017-01-31 | — | — | US | disclosed |
| US-9556227-B2 | Stitched polypeptides | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2017-01-31 | — | — | US | disclosed |
| US-20170022262-A1 | CRYSTALLINE INSULIN-CONJUGATES | SMARTCELLS, INC. (US) | 2017-01-26 | — | — | US | disclosed |
| WO-2017015575-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2017-01-26 | — | — | WO | disclosed |
| US-20170020645-A1 | METHOD OF TREATING URINARY INCONTINENCE | COLOPLAST A/S (DK) | 2017-01-26 | — | — | US | disclosed |
| US-20170023589-A1 | SURROGATES OF POST-TRANSLATIONALLY MODIFIED PROTEINS AND USES THEREOF | HARVARD COLLEGE (US) | 2017-01-26 | — | — | US | disclosed |
| US-9550000-B2 | Compositions, methods, and systems for the synthesis and use of imaging agents | LANTHEUS MEDICAL IMAGING, INC. (US) | 2017-01-24 | — | — | US | disclosed |
| US-9550744-B2 | Vitamin C prodrugs and uses thereof | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2017-01-24 | — | — | US | disclosed |
| WO-2017011730-A2 | PHENAZINE DERIVATIVES AS ANTIMICROBIAL AGENTS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2017-01-19 | — | — | WO | disclosed |
| US-9546146-B2 | Migrastatins and uses thereof | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2017-01-17 | — | — | US | disclosed |
| US-9546167-B2 | Radiosynthesis of tau radiopharmaceuticals | THE GENERAL HOSPITAL CORPORATION (US) | 2017-01-17 | — | — | US | disclosed |
| US-9547009-B2 | Benzocyclooctyne compounds and uses thereof | ACADEMIA SINICA (TW) | 2017-01-17 | — | — | US | disclosed |
| US-20170008895-A1 | USES OF DIAZEPANE DERIVATIVES | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2017-01-12 | — | — | US | disclosed |
| US-9540320-B2 | — | — | 2017-01-10 | — | — | US | disclosed |
| WO-2017004411-A1 | CORTISTATIN ANALOGUES AND SYNTHESES AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2017-01-05 | — | — | WO | disclosed |
| WO-2016210291-A1 | FUSED BICYCLIC PYRIMIDINE DERIVATIVES AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2016-12-29 | — | — | WO | disclosed |
| US-20160375006-A1 | USES OF PARALOG-SELECTIVE INHIBITORS OF GSK3 KINASES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-12-29 | — | — | US | disclosed |
| WO-2016210296-A1 | 4,6-PYRIMIDINYLENE DERIVATIVES AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2016-12-29 | — | — | WO | disclosed |
| US-20160367678-A1 | BOLAAMPHIPHILIC COMPOUNDS, COMPOSITIONS AND USES THEREOF | LAUREN SCIENCES LLC (US) | 2016-12-22 | — | — | US | disclosed |
| WO-2015148915-A9 | REACTIVE LABELLING COMPOUNDS AND USES THEREOF | ACADEMIA SINICA (TW) | 2016-12-22 | — | — | WO | disclosed |
| WO-2016205691-A1 | ALKENYL SUBSTITUTED 2,5-PIPERAZINEDIONES AND THEIR USE IN COMPOSITIONS FOR DELIVERING AN AGENT TO A SUBJECT OR CELL | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-12-22 | — | — | WO | disclosed |
| US-20160367686-A1 | ALKENYL SUBSTITUTED 2,5-PIPERAZINEDIONES, COMPOSITIONS, AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2016-12-22 | — | — | US | disclosed |
| US-20160368907-A1 | PRMT5 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2016-12-22 | — | — | US | disclosed |
| US-20160368910-A1 | INHIBITORS OF C-JUN-N-TERMINAL KINASE (JNK) | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2016-12-22 | — | — | US | disclosed |
| US-9522920-B2 | Bromodomain inhibitors and uses thereof | CONSTELLATION PHARMACEUTICALS, INC. (US) | 2016-12-20 | — | — | US | disclosed |
| US-20160361283-A1 | Isoprenyl Compounds and Methods Thereof | SIGNUM DERMALOGIX, INC. | 2016-12-15 | — | — | US | disclosed |
| WO-2016201374-A1 | SULFANIDE ADENOSINE DERIVATIVES AND USES THEREOF | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2016-12-15 | — | — | WO | disclosed |
| WO-2016201370-A1 | COMBINATION THERAPY OF TRANSCRIPTION INHIBITORS AND KINASE INHIBITORS | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2016-12-15 | — | — | WO | disclosed |
| US-20160362362-A1 | COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS | LANTHEUS MEDICAL IMAGING, INC. (US) | 2016-12-15 | — | — | US | disclosed |
| US-9518032-B2 | Small molecule inhibitors of USP1 deubiquitinating enzyme activity | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2016-12-13 | — | — | US | disclosed |
| US-20160355487-A1 | PHENAZINE DERIVATIVES AS ANTIMICROBIAL AGENTS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2016-12-08 | — | — | US | disclosed |
| US-20160354477-A1 | CONJUGATES OF TUMOR NECROSIS FACTOR INHIBITORS TO FUNCTIONALIZED POLYMERS | FISH & RICHARDSON PC | 2016-12-08 | — | — | US | disclosed |
| US-20160355537-A1 | TRIOXACARCINS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-12-08 | — | — | US | disclosed |
| EP-3099677-A1 | DIAMINOPYRIMIDINE BENZENESULFONE DERIVATIVES AND USES THEREOF | Dana-Farber Cancer Institute, Inc. (US) | 2016-12-07 | — | — | EP | disclosed |
| EP-3099696-A1 | DIAZEPANE DERIVATIVES AND USES THEREOF | Dana-Farber Cancer Institute, Inc. (US) | 2016-12-07 | — | — | EP | disclosed |
| EP-3099693-A1 | USES OF DIAZEPANE DERIVATIVES | Dana-Farber Cancer Institute, Inc. (US) | 2016-12-07 | — | — | EP | disclosed |
| US-9512073-B2 | Amino acid-, peptide-and polypeptide-lipids, isomers, compositions, and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-12-06 | — | — | US | disclosed |
| US-9512269-B2 | Methods for polymer synthesis | NOVOMER, INC. (US) | 2016-12-06 | — | — | US | disclosed |
| US-9512103-B2 | Synthesis of thiohydantoins | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2016-12-06 | — | — | US | disclosed |
| US-20160347750-A1 | DIHYDROPTERIDINONE DERIVATIVES AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2016-12-01 | — | — | US | disclosed |
| US-20160347749-A1 | DIAZEPANE DERIVATIVES AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2016-12-01 | — | — | US | disclosed |
| WO-2016191658-A1 | INHIBITORS OF BACTERIAL GLYCOSYL TRANSFERASES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-12-01 | — | — | WO | disclosed |
| US-9504695-B2 | Methods for reducing body fat | TOPOKINE THERAPEUTICS, INC. (US) | 2016-11-29 | — | — | US | disclosed |
| US-9505878-B2 | Catalysts and methods for polymer synthesis | NOVOMER, INC. (US) | 2016-11-29 | — | — | US | disclosed |
| US-9505735-B2 | Compounds for treating infectious diseases | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2016-11-29 | — | — | US | disclosed |
| US-20160340325-A1 | SYNTHESIS OF TETRACYCLINES AND ANALOGUES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-11-24 | — | — | US | disclosed |
| US-9499494-B2 | Pyrimidine-2,4,6-triones for use in the treatment of amyotrophic lateral sclerosis | NORTHWESTERN UNIVERSITY (US) | 2016-11-22 | — | — | US | disclosed |
| US-9498314-B2 | Urological device | COLOPLAST A/S (DK) | 2016-11-22 | — | — | US | disclosed |
| US-20160332993-A1 | DIAMINOPYRIMIDINE BENZENESULFONE DERIVATIVES AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2016-11-17 | — | — | US | disclosed |
| WO-2016182932-A1 | CORTISTATIN ANALOGUES, SYNTHESES, AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-11-17 | — | — | WO | disclosed |
| WO-2016182904-A1 | TARGETED SELECTION OF PATIENTS FOR TREATMENT WITH CORTISTATIN DERIVATIVES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-11-17 | — | — | WO | disclosed |
| EP-3092220-A1 | VITAMIN C PRODRUGS AND USES THEREOF | University of Florida Research Foundation, Inc. (US) | 2016-11-16 | — | — | EP | disclosed |
| US-9493580-B2 | Multivalent glycopeptide constructs and uses thereof | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2016-11-15 | — | — | US | disclosed |
| US-20160326157-A1 | MONOBACTAMS AND METHODS OF THEIR SYNTHESIS AND USE | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-11-10 | — | — | US | disclosed |
| CN-106103472-A | Stabilized polypeptides and uses thereof | 哈佛大学的校长及成员们 | 2016-11-09 | — | — | CN | disclosed |
| CN-106074591-A | RNA interference in eye disease | 雷克西制药公司 | 2016-11-09 | — | — | CN | disclosed |
| CN-106103452-A | Cortictatin analogs, their synthesis and use | 哈佛学院院长等 | 2016-11-09 | — | — | CN | disclosed |
| US-9486441-B2 | Compounds, compositions and methods for making the same | SIGNUM BIOSCIENCES, INC. (US) | 2016-11-08 | — | — | US | disclosed |
| US-9487562-B2 | Stabilized polypeptides as regulators of RAB GTPase function | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-11-08 | — | — | US | disclosed |
| US-9487472-B2 | Synthesis of acyclic and cyclic amines using iron-catalyzed nitrene group transfer | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-11-08 | — | — | US | disclosed |
| US-20160317279-A1 | VALVE | COLOPLAST A/S (DK) | 2016-11-03 | — | — | US | disclosed |
| US-20160318878-A1 | METHODS TO TREAT LYMPHOPLASMACYTIC LYMPHOMA | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2016-11-03 | — | — | US | disclosed |
| US-20160317498-A1 | HALOFUGINONE ANALOGS FOR INHIBITION OF TRNA SYNTHETASES AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-11-03 | — | — | US | disclosed |
| US-20160318920-A1 | TRPV1 ANTAGONISTS INCLUDING DIHYDROXY SUBSTITUENT AND USES THEREOF | PURDUE PHARMA L.P. | 2016-11-03 | — | — | US | disclosed |
| WO-2016176657-A1 | MITRAGYNINE ANALOGS AND USES THEREOF | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2016-11-03 | — | — | WO | disclosed |
| WO-2016176560-A1 | CHROMIUM-MEDIATED COUPLING AND APPLICATION TO THE SYNTHESIS OF HALICHONDRINS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-11-03 | — | — | WO | disclosed |
| WO-2016176343-A1 | METABOLICALLY PROGRAMMED METAL CHELATORS AND USES THEREOF | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2016-11-03 | — | — | WO | disclosed |
| EP-3087080-A1 | CORTISTATIN ANALOGUES AND SYNTHESES AND USES THEREOF | President and Fellows of Harvard College (US) | 2016-11-02 | — | — | EP | disclosed |
| EP-2512386-B1 | A GASTROINTESTINAL IMPLANT DEVICE | COLOPLAST AS (DK) | 2016-11-02 | — | — | EP | disclosed |
| EP-3086791-A2 | PHENAZINE DERIVATIVES AS ANTIMICROBIAL AGENTS | University of Florida Research Foundation, Inc. (US) | 2016-11-02 | — | — | EP | disclosed |
| CN-106068325-A | CHIRAL DESIGN | 波涛生命科学有限公司 | 2016-11-02 | — | — | CN | disclosed |
| WO-2016172631-A2 | SUBSTRATE SELECTIVE INHIBITORS OF INSULIN-DEGRADING ENZYME (IDE) AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-10-27 | — | — | WO | disclosed |
| US-20160311762-A1 | HYDRAZINYL LIPIDOIDS AND USES THEREOF | Preceres Inc. (US) | 2016-10-27 | — | — | US | disclosed |
| US-20160311807-A1 | METHODS TO TREAT LYMPHOPLASMACYTIC LYMPHOMA | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2016-10-27 | — | — | US | disclosed |
| US-9475776-B2 | PRMT1 inhibitors and uses thereof | Epizyme, Inc. (US) | 2016-10-25 | — | — | US | disclosed |
| WO-2016168580-A1 | BOLAAMPHIPHILIC COMPOUNDS, COMPOSITIONS AND USES THEREOF | LAUREN SCIENCES LLC (US) | 2016-10-20 | — | — | WO | disclosed |
| US-20160304875-A1 | METHODS FOR TREATMENT OF WOUND HEALING UTILIZING CHEMICALLY MODIFIED OLIGONUCLEOTIDES | RXI PHARMACEUTICALS CORPORATION (US) | 2016-10-20 | — | — | US | disclosed |
| US-20160303244-A1 | GLUCOSE-RESPONSIVE INSULIN CONJUGATES | MERCK SHARP & DOHME CORP. (US) | 2016-10-20 | — | — | US | disclosed |
| EP-2508531-B1 | Stitched polypeptides | HARVARD COLLEGE (US) | 2016-10-19 | — | — | EP | disclosed |
| EP-3079682-A2 | METHODS TO TREAT LYMPHOPLASMACYTIC LYMPHOMA | Dana-Farber Cancer Institute, Inc. (US) | 2016-10-19 | — | — | EP | disclosed |
| EP-3079683-A1 | METHODS TO TREAT LYMPHOPLASMACYTIC LYMPHOMA | Dana-Farber Cancer Institute, Inc. (US) | 2016-10-19 | — | — | EP | disclosed |
| US-20160296631-A1 | DRUG DELIVERY POLYMER AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-10-13 | — | — | US | disclosed |
| EP-3077050-A1 | METHODS FOR TREATMENT OF WOUND HEALING UTILIZING CHEMICALLY MODIFIED OLIGONUCLEOTIDES | RXi Pharmaceuticals Corporation (US) | 2016-10-12 | — | — | EP | disclosed |
| EP-2427438-B1 | PYRIMIDINE-2,4,6-TRIONES FOR USE IN THE TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS | CAMBRIA PHARMACEUTICALS INC (US) | 2016-10-12 | — | — | EP | disclosed |
| US-9463249-B2 | Crystalline insulin-conjugates | SMARTCELLS, INC. (US) | 2016-10-11 | — | — | US | disclosed |
| WO-2016160617-A2 | INHIBITORS OF CYCLIN-DEPENDENT KINASES | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2016-10-06 | — | — | WO | disclosed |
| US-20160289223-A1 | DESFERRITHIOCIN ANALOGS AND USES THEREOF | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2016-10-06 | — | — | US | disclosed |
| US-20160287734-A1 | 18F LABELING OF PROTEINS USING SORTASES | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2016-10-06 | — | — | US | disclosed |
| EP-3075248-A1 | USE OF ANTI-BACTERIAL AGENTS FOR THE TREATMENT OF EPITHELIAL-RELATED CONDITIONS | Signum Biosciences, Inc. (US) | 2016-10-05 | — | — | EP | disclosed |
| US-9458189-B2 | Ligation of stapled polypeptides | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-10-04 | — | — | US | disclosed |
| US-20160280693-A1 | ACTIVATORS OF CLASS I HISTONE DEACETLYASES (HDACS) AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-09-29 | — | — | US | disclosed |
| WO-2016154547-A1 | USE OF METAL CHELATORS IN MANAGING INFECTIOUS DISEASES | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2016-09-29 | — | — | WO | disclosed |
| US-20160280732-A1 | MOENOMYCIN ANALOGS, METHODS OF SYNTHESIS, AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-09-29 | — | — | US | disclosed |
| WO-2016154533-A1 | SYNTHESIS OF DESOSAMINES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-09-29 | — | — | WO | disclosed |
| WO-2016154591-A1 | MACROLIDES WITH MODIFIED DESOSAMINE SUGARS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-09-29 | — | — | WO | disclosed |
| WO-2016154317-A2 | POLYMERS, HYDROGELS, AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-09-29 | — | — | WO | disclosed |
| US-20160280827-A1 | POLYMERS, HYDROGELS, AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2016-09-29 | — | — | US | disclosed |
| WO-2016154051-A1 | COMBINATION THERAPY FOR TREATING INFECTIONS DISEASES | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2016-09-29 | — | — | WO | disclosed |
| EP-3071201-A1 | DESFERRITHIOCIN ANALOGS AND USES THEREOF | University of Florida Research Foundation, Inc. (US) | 2016-09-28 | — | — | EP | disclosed |
| US-20160272742-A1 | IRON COMPLEXES AND METHODS FOR POLYMERIZATION | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-09-22 | — | — | US | disclosed |
| US-20160272761-A1 | CATALYSTS AND METHODS FOR POLYMER SYNTHESIS | SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) | 2016-09-22 | — | — | US | disclosed |
| US-20160272593-A1 | FLUORINATION OF ORGANIC COMPOUNDS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-09-22 | — | — | US | disclosed |
| US-20160271268-A1 | NUCLEIC ACID NANOSTRUCTURES FOR IN VIVO AGENT DELIVERY | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2016-09-22 | — | — | US | disclosed |
| US-20160272623-A1 | FORMATION OF MACROMOLECULES USING ITERATIVE GROWTH AND RELATED COMPOUNDS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-09-22 | — | — | US | disclosed |
| CN-105960265-A | Method for treating wound healing using chemically modified oligonucleotides | 阿克赛医药公司 | 2016-09-21 | — | — | CN | disclosed |
| US-9447079-B2 | PRMT1 inhibitors and uses thereof | Epizyme, Inc. (US) | 2016-09-20 | — | — | US | disclosed |
| US-9447129-B2 | Suprametallogels and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-09-20 | — | — | US | disclosed |
| US-20160264554-A1 | POLYCYCLIC INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 (CDK7) | DANA-FARBER CANCER INSTITUTE, INC. | 2016-09-15 | — | — | US | disclosed |
| US-20160264728-A1 | POLYCARBONATE POLYOL COMPOSITIONS AND METHODS | SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) | 2016-09-15 | — | — | US | disclosed |
| US-20160264541-A1 | VITAMIN C PRODRUGS AND USES THEREOF | University of Florida Research Foundation, Inc.223 (US) | 2016-09-15 | — | — | US | disclosed |
| EP-3065722-A2 | NUCLEIC ACID NANOSTRUCTURES FOR IN VIVO AGENT DELIVERY | Dana-Farber Cancer Institute, Inc. (US) | 2016-09-14 | — | — | EP | disclosed |
| US-9440950-B2 | Arginine methyltransferase inhibitors and uses thereof | Epizyme, Inc. (US) | 2016-09-13 | — | — | US | disclosed |
| US-20160257725-A1 | BIFUNCTIONAL STAPLED POLYPEPTIDES AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-09-08 | — | — | US | disclosed |
| US-20160251407-A1 | GLUCOSE-RESPONSIVE INSULIN CONJUGATES | MERCK SHARP & DOHME CORP. (US) | 2016-09-01 | — | — | US | disclosed |
| US-20160251333-A1 | PROCESSES FOR THE PREPARATION OF (S)-3-(4-((4-(MORPHOLINOMETHYL)BENZYL)OXY)-1-OXOISOINDOLIN-2-YL)PIPERIDINE-2,6-DIONE AND PHARMACEUTICALLY ACCEPTABLE FORMS THEREOF | CELGENE CORPORATION | 2016-09-01 | — | — | US | disclosed |
| EP-3060257-A1 | LIPID FORMULATIONS FOR DELIVERY OF MESSENGER RNA | Shire Human Genetic Therapies, Inc. (US) | 2016-08-31 | — | — | EP | disclosed |
| US-9427475-B2 | Glucose-responsive insulin conjugates | MERCK SHARP & DOHME CORP. (US) | 2016-08-30 | — | — | US | disclosed |
| WO-2016134145-A2 | ARTIFICIAL SELF-SUFFICIENT CYTOCHROME P450S | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2016-08-25 | — | — | WO | disclosed |
| US-20160244494-A1 | STABILIZED POLYPEPTIDES AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-08-25 | — | — | US | disclosed |
| EP-3057956-A1 | POLYCYCLIC INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 (CDK7) | Dana-Farber Cancer Institute, Inc. (US) | 2016-08-24 | — | — | EP | disclosed |
| US-9422292-B2 | Bromodomain inhibitors and uses thereof | CONSTELLATION PHARMACEUTICALS, INC. (US) | 2016-08-23 | — | — | US | disclosed |
| US-20160237093-A1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | KALA BIO, Inc. | 2016-08-18 | — | — | US | disclosed |
| US-20160237094-A1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | KALA BIO, Inc. | 2016-08-18 | — | — | US | disclosed |
| US-20160235761-A1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | KALA BIO, Inc. | 2016-08-18 | — | — | US | disclosed |
| US-20160235753-A1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | KALA BIO, Inc. | 2016-08-18 | — | — | US | disclosed |
| EP-3056487-A1 | SYNTHESIS OF ENONE INTERMEDIATE | President and Fellows of Harvard College (US) | 2016-08-17 | — | — | EP | disclosed |
| CN-105873910-A | Macrocyclic insulin-degrading enzyme (IDE) inhibitors and uses thereof | 哈佛大学的校长及成员们 | 2016-08-17 | — | — | CN | disclosed |
| US-9415026-B2 | Use of anti-bacterial agents for the treatment of epithelial-related conditions | SIGNUM BIOSCIENCES, INC. (US) | 2016-08-16 | — | — | US | disclosed |
| US-9417248-B2 | Surrogates of post-translationally modified proteins and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-08-16 | — | — | US | disclosed |
| US-20160230201-A1 | LARGE SCALE ENZYMATIC SYNTHESIS OF OLIGOSACCHARIDES | ACADEMIA SINICA (TW) | 2016-08-11 | — | — | US | disclosed |
| US-20160229860-A1 | BICYCLIC ALKYNE DERIVATIVES AND USES THEREOF | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2016-08-11 | — | — | US | disclosed |
| EP-3052520-A2 | STABILIZED POLYPEPTIDES AND USES THEREOF | President and Fellows of Harvard College (US) | 2016-08-10 | — | — | EP | disclosed |
| EP-2391646-B1 | CRYSTALLINE INSULIN-CONJUGATES | SMARTCELLS INC (US) | 2016-08-10 | — | — | EP | disclosed |
| EP-3052134-A2 | GLUCOSE-RESPONSIVE INSULIN CONJUGATES | Merck Sharp & Dohme Corp. (US) | 2016-08-10 | — | — | EP | disclosed |
| EP-3052501-A1 | BICYCLIC ALKYNE DERIVATIVES AND USES THEREOF | Agency For Science, Technology And Research (SG) | 2016-08-10 | — | — | EP | disclosed |
| EP-2691396-B1 | ENOPEPTINS, USES THEREOF, AND METHODS OF SYNTHESIS THERETO | UNIV BROWN (US) | 2016-08-10 | — | — | EP | disclosed |
| CN-105849099-A | Polycyclic inhibitors of cyclin-dependent kinase 7 (CDK7) | 达纳-法伯癌症研究所股份有限公司 | 2016-08-10 | — | — | CN | disclosed |
| US-9409869-B1 | Hydrazinyl lipidoids and uses thereof | Preceres Inc. (US) | 2016-08-09 | — | — | US | disclosed |
| US-20160221960-A1 | Hydrazinyl Lipidoids and Uses Thereof | Preceres Inc. (US) | 2016-08-04 | — | — | US | disclosed |
| US-20160221984-A1 | MIGRASTATINS AND USES THEREOF | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH | 2016-08-04 | — | — | US | disclosed |
| WO-2016123397-A2 | MUTAGENIC NUCLEOSIDE ANALOGS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-08-04 | — | — | WO | disclosed |
| US-20160222050-A1 | MUTAGENIC NUCLEOSIDE ANALOGS AND USES THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-08-04 | — | — | US | disclosed |
| CN-103224474-B | The synthesis of tetracycline and the like | 哈佛大学校长及研究员协会 | 2016-08-03 | — | — | CN | disclosed |
| US-20160215036-A1 | STABILIZED POLYPEPTIDE INSULIN RECEPTOR MODULATORS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-07-28 | — | — | US | disclosed |
| US-20160213744-A1 | MACROCYCLIC INSULIN-DEGRADING ENZYME (IDE) INHIBITORS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-07-28 | — | — | US | disclosed |
| US-20160214985-A1 | PRMT5 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2016-07-28 | — | — | US | disclosed |
| US-20160214982-A1 | Radiosynthesis of Tau Radiopharmaceuticals | THE GENERAL HOSPITAL CORPORATION | 2016-07-28 | — | — | US | disclosed |
| EP-1753713-B1 | SYNTHESIS OF TETRACYCLINES AND ANALOGUES THEREOF | HARVARD COLLEGE (US) | 2016-07-27 | — | — | EP | disclosed |
| CN-105813656-A | LIPID FORMULATIONS FOR DELIVERY OF MESSENGER RNA | 夏尔人类遗传性治疗公司 | 2016-07-27 | — | — | CN | disclosed |
| WO-2016115463-A1 | INHIBITORS OF PHOSPHOGLYCERATE DEHYDROGENASE (PHGDH) AND USES THEREOF | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2016-07-21 | — | — | WO | disclosed |
| US-20160206740-A1 | CONJUGATED LIPOMERS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-07-21 | — | — | US | disclosed |
| US-20160206606-A1 | TOPICAL COMPOSITIONS COMPRISING A THIAZOLIDINEDIONE | TOPOKINE THERAPEUTICS, INC. (US) | 2016-07-21 | — | — | US | disclosed |
| US-20160207932-A1 | NOVEL TRICYCLIC CHIRAL COMPOUNDS AND THEIR USE IN ASYMMETRIC CATALYSIS | UNIV NANYANG TECH (SG) | 2016-07-21 | — | — | US | disclosed |
| CN-105792852-A | Glucose-responsive insulin conjugates | 默沙东公司 | 2016-07-20 | — | — | CN | disclosed |
| CN-105793262-A | Bicyclic alkyne derivatives and uses thereof | 新加坡科技研究局 | 2016-07-20 | — | — | CN | disclosed |
| US-9394258-B2 | Arginine methyltransferase inhibitors and uses thereof | Epizyme, Inc. (US) | 2016-07-19 | — | — | US | disclosed |
| US-9394326-B2 | Catalysts and methods for polymer synthesis | NOVOMER, INC. (US) | 2016-07-19 | — | — | US | disclosed |
| US-9394293-B2 | TRPV1 antagonists including dihydroxy substituent and uses thereof | PURDUE PHARMA L.P. (US) | 2016-07-19 | — | — | US | disclosed |
| US-9393329-B2 | N-alkoxyamide conjugates as imaging agents | LANTHEUS MEDICAL IMAGING, INC. (US) | 2016-07-19 | — | — | US | disclosed |
| EP-3041484-A1 | HUMAN iNKT CELL ACTIVATION USING GLYCOLIPIDS WITH ALTERED GLYCOSYL GROUPS | Academia Sinica (TW) | 2016-07-13 | — | — | EP | disclosed |
| US-9388125-B2 | Compositions, methods, and systems for the synthesis and use of imaging agents | LANTHEUS MEDICAL IMAGING, INC. (US) | 2016-07-12 | — | — | US | disclosed |
| US-9388277-B2 | Polycarbonate polyol compositions and methods | NOVOMER, INC. (US) | 2016-07-12 | — | — | US | disclosed |
| US-9388173-B2 | PRMT5 inhibitors and uses thereof | Epizyme, Inc. (US) | 2016-07-12 | — | — | US | disclosed |
| US-20160193310-A1 | RM2 ANTIGENS AND USE THEREOF | ACADEMIA SINICA | 2016-07-07 | — | — | US | disclosed |
| US-20160193351-A1 | CONJUGATE BASED SYSTEMS FOR CONTROLLED DRUG DELIVERY | SMARTCELLS, INC. (US) | 2016-07-07 | — | — | US | disclosed |
| EP-2877453-B1 | PROCESS FOR THE PREPARATION OF 4-AMINO-5-FLUORO-3-HALO-6-(SUBSTITUTED)PICOLINATES | DOW AGROSCIENCES LLC (US) | 2016-07-06 | — | — | EP | disclosed |
| CN-103200945-B | RNA interference in ocular symptoms | 雷克西制药公司 | 2016-07-06 | — | — | CN | disclosed |
| US-9382239-B2 | Inhibitors of c-Jun-N-terminal kinase (JNK) | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2016-07-05 | — | — | US | disclosed |
| US-9382227-B2 | Phenylethanolamine-based NMDA receptor antagonists | COLD SPRING HARBOR LABORATORY (US) | 2016-07-05 | — | — | US | disclosed |
| US-9381253-B2 | Drug delivery polymer and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-07-05 | — | — | US | disclosed |
| US-20160184075-A1 | BIOMATERIAL | COLOPLAST A/S (DK) | 2016-06-30 | — | — | US | disclosed |
| US-20160185772-A1 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | MAGSEIS FF LLC | 2016-06-30 | — | — | US | disclosed |
| US-20160184267-A1 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | Epizyme, Inc. | 2016-06-30 | — | — | US | disclosed |
| WO-2016105528-A2 | INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 (CDK7) | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2016-06-30 | — | — | WO | disclosed |
| US-9376383-B2 | Isoprenyl compounds | SIGNUM BIOSCIENCES, INC. (US) | 2016-06-28 | — | — | US | disclosed |
| US-9376531-B2 | Polycarbonate polyol compositions and methods | NOVOMER, INC. (US) | 2016-06-28 | — | — | US | disclosed |
| US-20160175421-A1 | GLYCAN CONJUGATES AND USE THEREOF | WONG CHI-HUEY (US) | 2016-06-23 | — | — | US | disclosed |
| WO-2016100444-A1 | TREATMENT OF CLOSED HEAD INJURY AND HEMORRHAGIC STROKE WITH HBED | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2016-06-23 | — | — | WO | disclosed |
| US-20160168205-A1 | METHODS AND COMPOSITIONS FOR LABELING POLYPEPTIDES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-06-16 | — | — | US | disclosed |
| US-20160168165-A1 | MYC MODULATORS AND USES THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-06-16 | — | — | US | disclosed |
| US-20160168154-A1 | INHIBITORS OF TRANSCRIPTION FACTORS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2016-06-16 | — | — | US | disclosed |
| WO-2016094688-A1 | FUSED 1,3-AZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF PROLIFERATIVE DISEASES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-06-16 | — | — | WO | disclosed |
| EP-3030239-A2 | UREA DERIVATIVES AND USES THEREOF | Kala Pharmaceuticals, Inc. (US) | 2016-06-15 | — | — | EP | disclosed |
| US-9365493-B2 | Synthesis of tetracyclines and analogues thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-06-14 | — | — | US | disclosed |
| US-9365555-B2 | PRMT5 inhibitors and uses thereof | Epizyme, Inc. | 2016-06-14 | — | — | US | disclosed |
| US-9363992-B2 | Hydrazinyl lipidoids and uses thereof | Preceres Inc. (US) | 2016-06-14 | — | — | US | disclosed |
| US-9365527-B2 | Arginine methyltransferase inhibitors and uses thereof | Epizyme, Inc. (US) | 2016-06-14 | — | — | US | disclosed |
| US-9365519-B2 | PRMT5 inhibitors and uses thereof | Epizyme, Inc. (US) | 2016-06-14 | — | — | US | disclosed |
| US-20160158363-A1 | MULTI-TAILED LIPIDS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-06-09 | — | — | US | disclosed |
| WO-2016090173-A1 | METHODS FOR THE TREATMENT OF ALOPECIA AREATA UTILIZING GENE MODULATION APPROACHES | RXI PHARMACEUTICALS CORPORATION (US) | 2016-06-09 | — | — | WO | disclosed |
| US-9359474-B2 | Catalysts and methods for polymer synthesis | NOVOMER, INC. (US) | 2016-06-07 | — | — | US | disclosed |
| EP-3024327-A2 | INHIBITORS OF TRANSCRIPTION FACTORS AND USES THEREOF | Dana-Farber Cancer Institute, Inc. (US) | 2016-06-01 | — | — | EP | disclosed |
| CN-103221382-B | Preparation pet precursor | GE HEALTHCARE LTD. (GB) | 2016-06-01 | — | — | CN | disclosed |
| US-9353122-B2 | Therapeutic compounds and uses thereof | KALA PHARMACEUTICALS, INC. (US) | 2016-05-31 | — | — | US | disclosed |
| US-9353123-B2 | Therapeutic compounds and uses thereof | KALA PHARMACEUTICALS, INC. (US) | 2016-05-31 | — | — | US | disclosed |
| US-9353061-B2 | 3,5,N-trihydroxy-alkanamide and derivatives: method for making same and use thereof | ACADEMIA SINICA (TW) | 2016-05-31 | — | — | US | disclosed |
| WO-2016081732-A1 | THIENOPYRIMIDINES AND USES THEREOF | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2016-05-26 | — | — | WO | disclosed |
| WO-2016080853-A1 | 2-THIOXOTHIAZOLIDIN-4-ONE DERIVATIVES ACTIVE AS TRANSTHYRETIN LIGANDS AND USES THEREOF | BSIM2 – BIOMOLECULAR SIMULATIONS LDA (PT) | 2016-05-26 | — | — | WO | disclosed |
| US-9346802-B2 | CARM1 inhibitors and uses thereof | Epizyme, Inc. (US) | 2016-05-24 | — | — | US | disclosed |
| US-9346761-B2 | Arginine methyltransferase inhibitors and uses thereof | Epizyme, Inc. (US) | 2016-05-24 | — | — | US | disclosed |
| US-20160137631-A1 | PRMT5 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2016-05-19 | — | — | US | disclosed |
| US-20160137785-A1 | POLY(BETA-AMINO ALCOHOLS), THEIR PREPARATION, AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-05-19 | — | — | US | disclosed |
| US-20160137777-A1 | CATALYSTS AND METHODS FOR POLYMER SYNTHESIS | SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) | 2016-05-19 | — | — | US | disclosed |
| WO-2016077581-A1 | ISOSTEVIOL TRIAZOLES AND USES THEREOF | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2016-05-19 | — | — | WO | disclosed |
| US-20160137609-A1 | PYRAZOLE DERIVATIVES AS ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2016-05-19 | — | — | US | disclosed |
| US-20160137646-A1 | Novel Compounds and Uses Thereof | KALA PHARMACEUTICALS, INC. (US) | 2016-05-19 | — | — | US | disclosed |
| CN-103415525-B | Bromine domain inhibitor and uses thereof | CONSTELLATION PHARMACEUTICALS, INC. (US) | 2016-05-18 | — | — | CN | disclosed |
| US-9340812-B2 | Large scale enzymatic synthesis of oligosaccharides | ACADEMIA SINICA (TW) | 2016-05-17 | — | — | US | disclosed |
| US-9339029-B2 | Hydrazinyl lipidoids and uses thereof | Preceres Inc. (US) | 2016-05-17 | — | — | US | disclosed |
| US-9340786-B2 | RNA interference in dermal and fibrotic indications | RXI PHARMACEUTICALS CORPORATION (US) | 2016-05-17 | — | — | US | disclosed |
| US-20160130578-A1 | REDUCED SIZE SELF-DELIVERING RNAI COMPOUNDS | PHIO PHARMACEUTICALS CORP. | 2016-05-12 | — | — | US | disclosed |
| WO-2016073956-A1 | EZH2 INHIBITORS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2016-05-12 | — | — | WO | disclosed |
| WO-2016073903-A1 | USE OF COMPOSITIONS MODULATING CHROMATIN STRUCTURE FOR GRAFT VERSUS HOST DISEASE (GVHD) | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2016-05-12 | — | — | WO | disclosed |
| US-20160122323-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 (CDK7) | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2016-05-05 | — | — | US | disclosed |
| EP-3013347-A1 | GLYCAN CONJUGATES AND USE THEREOF | Academia Sinica (TW) | 2016-05-04 | — | — | EP | disclosed |
| EP-3013365-A1 | RM2 ANTIGENS AND USE THEREOF | Academia Sinica (TW) | 2016-05-04 | — | — | EP | disclosed |
| US-9326515-B2 | Fungicidal 3-[(1,3-thiazol-4-ylmethoxyimino)(phenyl)methyl]-2-substituted-1,2,4-oxadiazol-5(2H)-one derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-05-03 | — | — | US | disclosed |
| US-9328117-B2 | Bromodomain inhibitors and uses thereof | CONSTELLATION PHARMACEUTICALS, INC. (US) | 2016-05-03 | — | — | US | disclosed |
| US-20160113750-A1 | UROLOGICAL DEVICE | VYSERA BIOMEDICAL LIMITED (IE) | 2016-04-28 | — | — | US | disclosed |
| US-20160115482-A1 | RNA INTERFERENCE IN OCULAR INDICATIONS | PHIO PHARMACEUTICALS CORP. | 2016-04-28 | — | — | US | disclosed |
| US-20160115162-A1 | Radiosynthesis of Tau Radiopharmaceuticals | THE GENERAL HOSPITAL CORPORATION | 2016-04-28 | — | — | US | disclosed |
| US-9321713-B2 | Hyperforin analogs, methods of synthesis, and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-04-26 | — | — | US | disclosed |
| US-20160106728-A1 | METHODS AND COMPOSITIONS FOR TREATING BETA-THALASSEMIA AND SICKLE CELL DISEASE | ACADEMIA SINICA (TW) | 2016-04-21 | — | — | US | disclosed |
| US-20160108018-A1 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2016-04-21 | — | — | US | disclosed |
| EP-3008081-A1 | STABILIZED POLYPEPTIDE INSULIN RECEPTOR MODULATORS | President and Fellows of Harvard College (US) | 2016-04-20 | — | — | EP | disclosed |
| US-9315635-B2 | Biomaterial | COLOPLAST A/S (DK) | 2016-04-19 | — | — | US | disclosed |
| US-9315472-B2 | 1,3,5-triazinane-2,4,6-trione derivatives and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-04-19 | — | — | US | disclosed |
| WO-2016057798-A1 | 14-MEMBERED KETOLIDES AND METHODS OF THEIR PREPARATION AND USE | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-04-14 | — | — | WO | disclosed |
| US-20160102116-A1 | HUMAN iNKT CELL ACTIVATION USING GLYCOLIPIDS | ACADEMIA SINICA (TW) | 2016-04-14 | — | — | US | disclosed |
| EP-3003314-A2 | NOVEL COMPOUNDS AND USES THEREOF | Kala Pharmaceuticals, Inc. (US) | 2016-04-13 | — | — | EP | disclosed |
| CN-105492428-A | Methods and compositions for treating beta-thalassemia and sickle cell disease | ACADEMIA SINICA | 2016-04-13 | — | — | CN | disclosed |
| US-9309220-B2 | Processes for the preparation of (S)-3-(4- (4-(morpholinomethyl)benzyl)oxy)-1-oxoisoindolin-2-yl)piperidine-2,6-dione and pharmaceutically acceptable forms thereof | CELGENE CORPORATION (US) | 2016-04-12 | — | — | US | disclosed |
| WO-2016054532-A1 | SELF-LABELING NUCLEIC ACIDS AND METHODS OF USE | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-04-07 | — | — | WO | disclosed |
| US-9303009-B2 | Migrastatins and uses thereof | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2016-04-05 | — | — | US | disclosed |
| CN-105452226-A | Tetrahydro-and dihydro-isoquinoline PRMT5 inhibitors and uses thereof | EPIZYME INC | 2016-03-30 | — | — | CN | disclosed |
| CN-101346468-B | amine-containing lipids and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-03-30 | — | — | CN | disclosed |
| WO-2016044650-A1 | CARM1 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2016-03-24 | — | — | WO | disclosed |
| WO-2016044641-A2 | CARM1 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2016-03-24 | — | — | WO | disclosed |
| WO-2016044626-A1 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2016-03-24 | — | — | WO | disclosed |
| WO-2016044585-A1 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2016-03-24 | — | — | WO | disclosed |
| US-9290591-B2 | Iron complexes and methods for polymerization | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-03-22 | — | — | US | disclosed |
| WO-2016040369-A2 | HUMAN iNKT CELL ACTIVATION USING GLYCOLIPIDS | ACADEMIA SINICA (TW) | 2016-03-17 | — | — | WO | disclosed |
| US-20160073629-A1 | Hydrazinyl Lipidoids and Uses Thereof | Preceres Inc. (US) | 2016-03-17 | — | — | US | disclosed |
| US-9284297-B2 | Halofuginone analogs for inhibition of tRNA synthetases and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-03-15 | — | — | US | disclosed |
| US-9284406-B2 | Catalysts and methods for polymer synthesis | NOVOMER, INC. (US) | 2016-03-15 | — | — | US | disclosed |
| US-20160067346-A1 | BRUSH-POLY (GLYCOAMIDOAMINE)-LIPIDS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-03-10 | — | — | US | disclosed |
| US-20160066569-A1 | Hydrazinyl Lipidoids and Uses Thereof | Preceres Inc. (US) | 2016-03-10 | — | — | US | disclosed |
| US-20160067276-A1 | HOLLOW PARTICLES ENCAPSULATING A BIOLOGICAL GAS AND METHODS OF USE | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2016-03-10 | — | — | US | disclosed |
| US-20160067263-A1 | METHODS AND COMPOSITIONS FOR TOPICAL DELIVERY OF PROSTAGLANDINS TO SUBCUTANEOUS FAT | TOPOKINE THERAPEUTICS, INC. (US) | 2016-03-10 | — | — | US | disclosed |
| WO-2016037072-A2 | ENOPEPTIN ANALOGAS AND METHODS OF USE THEREOF | BROWN UNIVERSITY (US) | 2016-03-10 | — | — | WO | disclosed |
| WO-2016036966-A1 | HYDRAZINYL LIPIDOIDS AND USES THEREOF | Preceres Inc. (US) | 2016-03-10 | — | — | WO | disclosed |
| WO-2016037071-A2 | METHODS FOR TREATING AGING AND SKIN DISORDERS USING NUCLEIC ACIDS TARGETING TYR OR MMP1 | RXI PHARMACEUTICALS CORPORATION (US) | 2016-03-10 | — | — | WO | disclosed |
| EP-2991665-A1 | STAPLED AND STITCHED POLYPEPTIDES AND USES THEREOF | President and Fellows of Harvard College (US) | 2016-03-09 | — | — | EP | disclosed |
| US-9278916-B2 | Preparation of pet precursor | GE HEALTHCARE LIMITED (GB) | 2016-03-08 | — | — | US | disclosed |
| US-20160060264-A1 | UREA DERIVATIVES AND USES THEREOF | KALA BIO, Inc. | 2016-03-03 | — | — | US | disclosed |
| EP-2988597-A2 | MACROLIDES AND METHODS OF THEIR PREPARATION AND USE | President and Fellows of Harvard College (US) | 2016-03-02 | — | — | EP | disclosed |
| US-9273083-B2 | Nickel fluorinating complexes and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-03-01 | — | — | US | disclosed |
| US-9273084-B2 | Moenomycin analogs, methods of synthesis, and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-03-01 | — | — | US | disclosed |
| US-20160052951-A1 | MACROLIDES AND METHODS OF THEIR PREPARATION AND USE | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-02-25 | — | — | US | disclosed |
| US-20160052922-A1 | 1-PHENOXY-3-(ALKYLAMINO)-PROPAN-2-OL DERIVATIVES AS CARM1 INHIBITORS AND USES THEREOF | Epizyme. Inc. (US) | 2016-02-25 | — | — | US | disclosed |
| US-20160051562-A1 | METHODS AND COMPOSITIONS FOR REDUCING BODY FAT AND ADIPOCYTES | TOPOKINE THERAPEUTICS, INC. (US) | 2016-02-25 | — | — | US | disclosed |
| US-9266836-B2 | PRMT5 inhibitors and uses thereof | Epizyme, Inc. (US) | 2016-02-23 | — | — | US | disclosed |
| US-9265838-B2 | Conjugate based systems for controlled drug delivery | SMART CELLS, INC. (US) | 2016-02-23 | — | — | US | disclosed |
| US-20160046661-A1 | RAS INHIBITORS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2016-02-18 | — | — | US | disclosed |
| WO-2016025643-A1 | BRUSH-POLY(GLYCOAMIDOAMINE)-LIPIDS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-02-18 | — | — | WO | disclosed |
| US-20160046674-A1 | ENOPEPTINS, USES THEREOF, AND METHODS OF SNYTHESIS THEREOF | BROWN UNIVERSITY (US) | 2016-02-18 | — | — | US | disclosed |
| EP-2983659-A1 | DRUG DELIVERY POLYMER AND USES THEREOF | Massachusetts Institute of Technology (US) | 2016-02-17 | — | — | EP | disclosed |
| EP-2675278-B1 | METHODS FOR SYNTHESIZING MOLYBDOPTERIN PRECURSOR Z DERIVATIVES | ALEXION PHARMA INTERNAT SÀRL (CH) | 2016-02-17 | — | — | EP | disclosed |
| CN-105338812-A | Benzimidazole derivatives and uses thereof | WHITEHEAD BIOMEDICAL INST | 2016-02-17 | — | — | CN | disclosed |
| CN-105339351-A | Arginine methyltransferase inhibitors and uses thereof | EPIZYME INC | 2016-02-17 | — | — | CN | disclosed |
| US-9260462-B2 | Methods for synthesizing molybdopterin precursor Z derivatives | ALEXION PHARMACEUTICALS, INC. (US) | 2016-02-16 | — | — | US | disclosed |
| US-20160039823-A1 | Meropenem Derivatives and Uses Thereof | KALA PHARMACEUTICALS, INC. (US) | 2016-02-11 | — | — | US | disclosed |
| US-20160039834-A1 | CARM1 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2016-02-11 | — | — | US | disclosed |
| WO-2016022970-A1 | DIHYDROPTERIDINONE DERIVATIVES AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2016-02-11 | — | — | WO | disclosed |
| WO-2016022902-A1 | DIAZEPANE DERIVATIVES AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2016-02-11 | — | — | WO | disclosed |
| US-20160039767-A1 | PYRAZOLE DERIVATIVES AS PRMT1 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2016-02-11 | — | — | US | disclosed |
| US-20160039740-A1 | Cyclohexane-1,3-Diones for Use in the Treatment of Amyotrophic Lateral Sclerosis | CAMBRIA PHARMACEUTICALS DISTRIBUTING TRUST | 2016-02-11 | — | — | US | disclosed |
| WO-2016023014-A2 | USES OF SALT-INDUCIBLE KINASE (SIK) INHIBITORS | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2016-02-11 | — | — | WO | disclosed |
| EP-2982373-A1 | METHODS AND COMPOSTIONS FOR REDUCING BODY FAT | Topokine Therapeutics, Inc. (US) | 2016-02-10 | — | — | EP | disclosed |
| US-20160030596-A1 | GAS-FILLED STABILIZED PARTICLES AND METHODS OF USE | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2016-02-04 | — | — | US | disclosed |
| US-20160033519-A1 | BROMODOMAIN BINDING REAGENTS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2016-02-04 | — | — | US | disclosed |
| US-20160031839-A1 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2016-02-04 | — | — | US | disclosed |
| US-20160031824-A1 | BENZIMIDAZOLE DERIVATIVES AND USES THEREOF | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2016-02-04 | — | — | US | disclosed |
| EP-2487160-B1 | Synthesis of Enone Intermediate | HARVARD COLLEGE (US) | 2016-02-03 | — | — | EP | disclosed |
| CN-105287472-A | Antibacterial agent for treating the related state of illness about epithelium | SIGNUM BIOSCIENCES INC | 2016-02-03 | — | — | CN | disclosed |
| US-9249161-B2 | Bromodomain inhibitors and uses thereof | CONSTELLATION PHARMACEUTICALS, INC. (US) | 2016-02-02 | — | — | US | disclosed |
| US-20160024016-A1 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2016-01-28 | — | — | US | disclosed |
| US-20160022794-A1 | SIDEROPHORE-BASED IMMUNIZATION AGAINST GRAM-NEGATIVE BACTERIA | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-01-28 | — | — | US | disclosed |
| US-20160022817-A1 | Photoswitchable HDAC Inhibitors | THE GENERAL HOSPITAL CORPORATION (US) | 2016-01-28 | — | — | US | disclosed |
| WO-2016014551-A1 | MACROCYCLIC KINASE INHIBITORS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2016-01-28 | — | — | WO | disclosed |
| US-20160022701-A1 | NEUROACTIVE STEROIDS, COMPOSITIONS, AND USES THEREOF | SAGE THERAPEUTICS INC (US) | 2016-01-28 | — | — | US | disclosed |
| US-20160024017-A1 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2016-01-28 | — | — | US | disclosed |
| WO-2016014542-A1 | IMIDAZOLYL KINASE INHIBITORS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2016-01-28 | — | — | WO | disclosed |
| US-20160024153-A1 | STAPLED AND STITCHED POLYPEPTIDES AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-01-28 | — | — | US | disclosed |
| US-9243038-B2 | Macrocyclic insulin-degrading enzyme (IDE) inhibitors and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-01-26 | — | — | US | disclosed |
| US-20160016911-A1 | Treatment of Amyotrophic Lateral Sclerosis | NORTHWESTERN UNIVERSITY | 2016-01-21 | — | — | US | disclosed |
| US-20160015837-A1 | HSP90-TARGETED CARDIAC IMAGING AND THERAPY | MEMORIAL SLOAN-KETTERING CANCER CENTER | 2016-01-21 | — | — | US | disclosed |
| WO-2016011130-A1 | COMPOSITIONS AND METHODS FOR THE PREPARATION OF 4-OXY-2-CYCLOHEXENONE AND 6-OXY-2-CYCLOHEXENONE COMPOUNDS | NATIONAL TAIWAN UNIVERSITY (TW) | 2016-01-21 | — | — | WO | disclosed |
| EP-2970360-A1 | RAS INHIBITORS AND USES THEREOF | Dana-Farber Cancer Institute, Inc. (US) | 2016-01-20 | — | — | EP | disclosed |
| EP-2970266-A1 | 1 -PHENOXY-3-(ALKYLAMINO)-PROPAN-2-OL DERIVATIVES AS CARM1 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2016-01-20 | — | — | EP | disclosed |
| EP-2970132-A1 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2016-01-20 | — | — | EP | disclosed |
| EP-2970181-A1 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2016-01-20 | — | — | EP | disclosed |
| EP-2970219-A1 | CARM1 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2016-01-20 | — | — | EP | disclosed |
| EP-2721031-B1 | BROMODOMAIN INHIBITORS AND USES THEREOF | CONSTELLATION PHARMACEUTICALS INC (US) | 2016-01-20 | — | — | EP | disclosed |
| EP-2970136-A1 | ARGININE METHYL TRANSFERASE INHIBTORS AND USES THEREOF | Epizyme, Inc. (US) | 2016-01-20 | — | — | EP | disclosed |
| EP-2970504-A1 | NEUROACTIVE STEROIDS, COMPOSITIONS, AND USES THEREOF | Sage Therapeutics, Inc. (US) | 2016-01-20 | — | — | EP | disclosed |
| EP-2967046-A1 | BENZIMIDAZOLE DERIVATIVES AND USES THEREOF | Whitehead Institute for Biomedical Research (US) | 2016-01-20 | — | — | EP | disclosed |
| EP-2970135-A1 | PYRAZOLE DERIVATIVES AS PRMT1 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2016-01-20 | — | — | EP | disclosed |
| EP-2968274-A1 | MEROPENEM DERIVATIVES AND USES THEREOF | Kala Pharmaceuticals, Inc. (US) | 2016-01-20 | — | — | EP | disclosed |
| EP-2970131-A2 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2016-01-20 | — | — | EP | disclosed |
| EP-2970137-A1 | PYRAZOLE DERIVATIVES AS ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2016-01-20 | — | — | EP | disclosed |
| EP-2970220-A2 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2016-01-20 | — | — | EP | disclosed |
| EP-2968163-A1 | HOLLOW PARTICLES ENCAPSULATING A BIOLOGICAL GAS AND METHODS OF USE | Children's Medical Center Corporation (US) | 2016-01-20 | — | — | EP | disclosed |
| EP-2970134-A1 | PYRAZOLE DERIVATIVES ASPRMT1 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2016-01-20 | — | — | EP | disclosed |
| EP-2970133-A1 | PYRAZOLE DERIVATIVES AS PRMT1 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2016-01-20 | — | — | EP | disclosed |
| EP-2972394-A1 | HSP90-TARGETED CARDIAC IMAGING AND THERAPY | Memorial Sloan Kettering Cancer Center (US) | 2016-01-20 | — | — | EP | disclosed |
| EP-2968825-A1 | GAS-FILLED STABILIZED PARTICLES AND METHODS OF USE | Children's Medical Center Corporation (US) | 2016-01-20 | — | — | EP | disclosed |
| US-9238596-B2 | Process simplification for precursor compound | GE HEALTHCARE LIMITED (GB) | 2016-01-19 | — | — | US | disclosed |
| US-9238716-B2 | Conjugated lipomers and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-01-19 | — | — | US | disclosed |
| US-20160009747-A1 | PLATINUM METALLACYCLES COMPRISING N, P, OR AS RINGATOMS AND THEIR USE AS CATALYSTS IN 1,2-HYDROSILYLATION REACTIONS OF DIENES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-01-14 | — | — | US | disclosed |
| US-20160009657-A1 | AMINE-CONTAINING LIPIDS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-01-14 | — | — | US | disclosed |
| EP-2966108-A2 | Catalysts and methods for polymer synthesis | Novomer, Inc. (US) | 2016-01-13 | — | — | EP | disclosed |
| CN-105246334-A | Macrolides and methods of making and using the same | HARVARD COLLEGE | 2016-01-13 | — | — | CN | disclosed |
| WO-2016003975-A1 | SYNTHESIS OF HALICHONDRIN ANALOGS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-01-07 | — | — | WO | disclosed |
| WO-2016004180-A1 | O-GLCNAC TRANSFERASE (OGT) INHIBITORS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-01-07 | — | — | WO | disclosed |
| WO-2016004202-A1 | POLYAMINE-FATTY ACID DERIVED LIPIDOIDS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-01-07 | — | — | WO | disclosed |
| US-20160002254-A1 | Therapeutic Compounds and Uses Thereof | KALA PHARMACEUTICALS, INC. (US) | 2016-01-07 | — | — | US | disclosed |
| US-20160002178-A1 | POLYAMINE-FATTY ACID DERIVED LIPIDOIDS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-01-07 | — | — | US | disclosed |
| US-20160002183-A1 | SYNTHESIS OF TETRACYCLINES AND INTERMEDIATES THERETO | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-01-07 | — | — | US | disclosed |
| US-20160002145-A1 | SYNTHESIS OF ACYCLIC AND CYCLIC AMINES USING IRON-CATALYZED NITRENE GROUP TRANSFER | PRESIDENT AND FELLOWS OF HARVARD (US) | 2016-01-07 | — | — | US | disclosed |
| EP-2963012-A1 | ISOPRENYL COMPOUNDS AND METHODS THEREOF | Signum Biosciences, Inc. (US) | 2016-01-06 | — | — | EP | disclosed |
| CN-102655745-B | Use of antibacterial agents for treating epithelial-related conditions | SIGNUM BIOSCIENCES, INC. (US) | 2016-01-06 | — | — | CN | disclosed |
| CN-105228997-A | Carm1 inhibitors and uses thereof | EPIZYME INC | 2016-01-06 | — | — | CN | disclosed |
| US-20150376227-A1 | LIGATION OF STAPLED POLYPEPTIDES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-12-31 | — | — | US | disclosed |
| US-20150376201-A1 | CORTISTATIN ANALOGUES AND SYNTHESES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-12-31 | — | — | US | disclosed |
| EP-2958895-A1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | Kala Pharmaceuticals, Inc. (US) | 2015-12-30 | — | — | EP | disclosed |
| WO-2015200677-A2 | PRMT5 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2015-12-30 | — | — | WO | disclosed |
| WO-2015200680-A2 | PRMT5 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2015-12-30 | — | — | WO | disclosed |
| WO-2015200425-A1 | TOPICAL DOSAGE REGIMEN | TOPOKINE THERAPEUTICS, INC. (US) | 2015-12-30 | — | — | WO | disclosed |
| CN-105209015-A | Compositions and methods for local delivery of prostaglandins to subcutaneous fat | TOPOKINE THERAPEUTICS INC | 2015-12-30 | — | — | CN | disclosed |
| US-9220789-B2 | Conjugates of tumor necrosis factor inhibitors to functionalized polymers | QUIAPEG PHARMACEUTICALS AB (SE) | 2015-12-29 | — | — | US | disclosed |
| US-9221794-B2 | PRMT5 inhibitors and uses thereof | Epizyme, Inc. (US) | 2015-12-29 | — | — | US | disclosed |
| EP-2956138-A1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | Kala Pharmaceuticals, Inc. (US) | 2015-12-23 | — | — | EP | disclosed |
| WO-2015196072-A2 | USES OF KINASE INHIBITORS FOR INDUCING AND MAINTAINING PLURIPOTENCY | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2015-12-23 | — | — | WO | disclosed |
| US-20150361042-A1 | PRMT5 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2015-12-17 | — | — | US | disclosed |
| US-9212381-B2 | Methods and compositions for labeling polypeptides | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-12-15 | — | — | US | disclosed |
| US-9212145-B2 | Urea derivatives and uses thereof | KALA PHARMACEUTICALS, INC. (US) | 2015-12-15 | — | — | US | disclosed |
| US-20150353503-A1 | INDAZOLE DERIVATIVES AND USES THEREOF | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2015-12-10 | — | — | US | disclosed |
| CN-105131067-A | RNA INTERFERENCE IN DERMAL AND FIBROTIC INDICATIONS | RXI PHARMACEUTICALS CORP | 2015-12-09 | — | — | CN | disclosed |
| US-9206090-B2 | Tricyclic chiral compounds and their use in asymmetric catalysis | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2015-12-08 | — | — | US | disclosed |
| US-20150344434-A1 | TETRAHYDRO- AND DIHYDRO-ISOQUINOLINE PRMT5 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2015-12-03 | — | — | US | disclosed |
| WO-2015184451-A1 | MINIMAL SAPONIN ANALOGUES, SYNTHESIS AND USE THEREOF | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2015-12-03 | — | — | WO | disclosed |
| WO-2015184256-A2 | BIODEGRADABLE LIPIDS FOR DELIVERY OF NUCLEIC ACIDS | SHIRE HUMAN GENETIC THERAPIES, INC. (US) | 2015-12-03 | — | — | WO | disclosed |
| US-20150344513-A9 | METHODS AND INTERMEDIATES FOR THE PREPARATION OF FONDAPARINUX | ACADEMIA SINICA (TW) | 2015-12-03 | — | — | US | disclosed |
| US-20150344503-A1 | INHIBITORS OF FATTY ACID AMIDE HYDROLASE, METHODS OF TREATMENT AND METHODS OF PREPARING SAME | INFINITY PHARMACEUTICALS INC (US) | 2015-12-03 | — | — | US | disclosed |
| US-20150344433-A1 | PRMT5 INHIBITORS CONTAINING A DIHYDRO- OR TETRAHYDROISOQUINOLINE AND USES THEREOF | Epizyme, Inc. (US) | 2015-12-03 | — | — | US | disclosed |
| US-20150344463-A1 | PRMT5 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2015-12-03 | — | — | US | disclosed |
| US-20150344457-A1 | METHODS OF INHIBITING PRMT5 | Epizyme, Inc. (US) | 2015-12-03 | — | — | US | disclosed |
| WO-2015179282-A1 | TOPICAL COMPOSITIONS COMPRISING A THIAZOLIDINEDIONE | TOPOKINE THERAPEUTICS, INC. (US) | 2015-11-26 | — | — | WO | disclosed |
| US-9193989-B2 | PRPK-TPRKB modulators and uses thereof | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2015-11-24 | — | — | US | disclosed |
| US-9193665-B2 | Synthesis of galanal compounds and analogues thereof | ACADEMIA SINICA (TW) | 2015-11-24 | — | — | US | disclosed |
| US-9193767-B2 | Enopeptins, uses thereof, and methods of synthesis thereto | BROWN UNIVERSITY (US) | 2015-11-24 | — | — | US | disclosed |
| US-9193827-B2 | Poly(beta-amino alcohols), their preparation, and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2015-11-24 | — | — | US | disclosed |
| WO-2015175707-A1 | HSP70 MODULATORS AND METHODS FOR MAKING AND USING THE SAME | MEMORIAL SLOAN KETTERING CANCER CENTER (US) | 2015-11-19 | — | — | WO | disclosed |
| CN-105073768-A | Ras inhibitors and uses thereof | DANA FARBER CANCER INST INC | 2015-11-18 | — | — | CN | disclosed |
| US-9180130-B2 | Tafluprost and analogs thereof for reducing fat | TOPOKINE THERAPEUTICS, INC. (US) | 2015-11-10 | — | — | US | disclosed |
| US-20150315286-A1 | GLYCATED CD59 PEPTIDES, THEIR PREPARATION, AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2015-11-05 | — | — | US | disclosed |
| US-20150313825-A1 | METHODS AND COMPOSITIONS FOR LOCALLY INCREASING BODY FAT | TOPOKINE THERAPEUTICS, INC. (US) | 2015-11-05 | — | — | US | disclosed |
| US-20150313890-A1 | KINASE INHIBITORS AND METHODS OF USE THEREOF | THE BROAD INSTITUTE, INC. (US) | 2015-11-05 | — | — | US | disclosed |
| WO-2015168605-A1 | METHODS FOR TREATMENT OF DISORDERS IN THE FRONT OF THE EYE UTILIZING NUCLEIC ACID MOLECULES | RXI PHARMACEUTICALS CORPORATION (US) | 2015-11-05 | — | — | WO | disclosed |
| WO-2015168108-A2 | METHODS FOR TREATING CANCER USING NUCLEIC TARGETING MDM2 OR MYCN | RXI PHARMACEUTICALS CORPORATION (US) | 2015-11-05 | — | — | WO | disclosed |
| WO-2015168380-A1 | SIDEROPHORE-BASED IMMUNIZATION AGAINST GRAM-NEGATIVE BACTERIA | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2015-11-05 | — | — | WO | disclosed |
| US-20150309041-A1 | REACTIVE LABELLING COMPOUNDS AND USES THEREOF | ACADEMIA SINICA (TW) | 2015-10-29 | — | — | US | disclosed |
| US-20150306236-A1 | BOLAAMPHIPHILIC COMPOUNDS, COMPOSITIONS AND USES THEREOF | LAUREN SCIENCES LLC | 2015-10-29 | — | — | US | disclosed |
| WO-2015164604-A1 | HYDROPHOBICALLY TAGGED JANUS KINASE INHIBITORS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2015-10-29 | — | — | WO | disclosed |
| WO-2015164614-A1 | JANUS KINASE INHIBITORS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2015-10-29 | — | — | WO | disclosed |
| EP-2935241-A1 | PRMT5 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2015-10-28 | — | — | EP | disclosed |
| EP-2935240-A1 | PRMT5 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2015-10-28 | — | — | EP | disclosed |
| EP-2935247-A1 | PRMT5 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2015-10-28 | — | — | EP | disclosed |
| EP-2935243-A1 | PRMT5 INHIBITORS CONTAINING A DIHYDRO- OR TETRAHYDROISOQUINOLINE AND USES THEREOF | Epizyme, Inc. (US) | 2015-10-28 | — | — | EP | disclosed |
| EP-2935222-A2 | PRMT5 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2015-10-28 | — | — | EP | disclosed |
| EP-2935242-A2 | METHODS OF INHIBITING PRMT5 | Epizyme, Inc. (US) | 2015-10-28 | — | — | EP | disclosed |
| US-20150297747-A1 | TRIOXACARCINS, TRIOXACARCIN-ANTIBODY CONJUGATES, AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-10-22 | — | — | US | disclosed |
| US-20150299386-A1 | POLYCARBONATE POLYOL COMPOSITIONS AND METHODS | SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) | 2015-10-22 | — | — | US | disclosed |
| EP-2755949-B1 | FUNGICIDAL 4-SUBSTITUTED-3-{PHENYL[(HETEROCYCLYLMETHOXY)IMINO]METHYL}-1,2,4-OXADIZOL-5(4H)-ONE DERIVATIVES | BAYER IP GMBH (DE) | 2015-10-21 | — | — | EP | disclosed |
| US-9163330-B2 | Bifunctional stapled polypeptides and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-10-20 | — | — | US | disclosed |
| US-9162968-B2 | Cyclohexane-1,3-diones for use in the treatment of amyotrophic lateral sclerosis | NORTHWESTERN UNIVERSITY (US) | 2015-10-20 | — | — | US | disclosed |
| US-20150291521-A1 | PYRROL-1-YL BENZOIC ACID DERIVATIVES USEFUL AS MYC INHIBITORS | DANA-FARBER CANCER INSTITUTE, INC. | 2015-10-15 | — | — | US | disclosed |
| US-20150291654-A1 | 3,3 DISUBSTITUTED 19-NOR PREGNANE COMPOUNDS, COMPOSITIONS, AND USES THEREOF | SAGE THERAPEUTICS, INC. (US) | 2015-10-15 | — | — | US | disclosed |
| WO-2015153401-A1 | PHOSPHATE BASED LINKERS FOR INTRACELLULAR DELIVERY OF DRUG CONJUGATES | MERCK SHARP & DOHME CORP (US) | 2015-10-08 | — | — | WO | disclosed |
| US-20150284334-A1 | PRMT1 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2015-10-08 | — | — | US | disclosed |
| US-20150284437-A1 | BETA-CATENIN TARGETING PEPTIDES AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-10-08 | — | — | US | disclosed |
| US-20150284356-A1 | COMPOUNDS FOR TREATING INFECTIOUS DISEASES | Whatehead Institute for Biomedical Research (US) | 2015-10-08 | — | — | US | disclosed |
| US-9149465-B2 | Isoxazolines as inhibitors of fatty acid amide hydrolase | INFINITY PHARMACEUTICALS, INC. (US) | 2015-10-06 | — | — | US | disclosed |
| WO-2015148915-A1 | REACTIVE LABELLING COMPOUNDS AND USES THEREOF | ACADEMIA SINICA (TW) | 2015-10-01 | — | — | WO | disclosed |
| US-20150274738-A1 | HYDROPHOBICALLY TAGGED SMALL MOLECULES AS INDUCERS OF PROTEIN DEGRADATION | Dana-Farber Cancer, Institute, Inc. (US) | 2015-10-01 | — | — | US | disclosed |
| EP-2922542-A1 | METHODS AND COMPOSITIONS FOR LOCALLY INCREASING BODY FAT | Topokine Therapeutics, Inc. (US) | 2015-09-30 | — | — | EP | disclosed |
| EP-2797891-B1 | FUNGICIDAL 3-[(PYRIDIN-2-YLMETHOXYIMINO)(PHENYL)METHYL]-2-SUBSTITUTED-1,2,4-OXADIAZOL-5(2H)-ONE DERIVATIVES | BAYER IP GMBH (DE) | 2015-09-30 | — | — | EP | disclosed |
| EP-2922575-A1 | TRIOXACARCINS, TRIOXACARCIN-ANTIBODY CONJUGATES, AND USES THEREOF | President and Fellows of Harvard College (US) | 2015-09-30 | — | — | EP | disclosed |
| US-9145424-B2 | Treatment of amyotrophic lateral sclerosis | NORTHWESTERN UNIVERSITY (US) | 2015-09-29 | — | — | US | disclosed |
| US-20150265717-A1 | CONJUGATE BASED SYSTEMS FOR CONTROLLED DRUG DELIVERY | SMARTCELLS, INC. (US) | 2015-09-24 | — | — | US | disclosed |
| EP-2920197-A2 | PROLINE-LOCKED STAPLED PEPTIDES AND USES THEREOF | President and Fellows of Harvard College (US) | 2015-09-23 | — | — | EP | disclosed |
| CN-103108642-B | RNA interference in cutaneous and fibrotic conditions | Lexie Pharmaceuticals (US) | 2015-09-23 | — | — | CN | disclosed |
| US-20150259298-A1 | THIOHYDANTOIN DERIVATIVES AND USES THEREOF | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2015-09-17 | — | — | US | disclosed |
| EP-2917203-A1 | PYRROL-1 -YL BENZOIC ACID DERIVATIVES USEFUL AS MYC INHIBITORS | Dana-Farber Cancer Institute, Inc. (US) | 2015-09-16 | — | — | EP | disclosed |
| US-9133189-B2 | Arginine methyltransferase inhibitors and uses thereof | Epizyme, Inc. (US) | 2015-09-15 | — | — | US | disclosed |
| US-20150252145-A1 | CATALYSTS AND METHODS FOR POLYMER SYNTHESIS | SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) | 2015-09-10 | — | — | US | disclosed |
| US-20150252031-A1 | PRMT5 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2015-09-10 | — | — | US | disclosed |
| US-20150252067-A1 | NICKEL FLUORINATING COMPLEXES AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-09-10 | — | — | US | disclosed |
| CN-104888857-A | CATALYSTS AND METHODS FOR POLYMER SYNTHESIS | NOVOMER INC | 2015-09-09 | — | — | CN | disclosed |
| US-9127019-B2 | Cortistatin analogues and synthesis thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-09-08 | — | — | US | disclosed |
| US-20150246138-A1 | BOLAAMPHIPHILIC COMPOUNDS, COMPOSITIONS AND USES THEREOF | LAUREN SCIENCES LLC | 2015-09-03 | — | — | US | disclosed |
| US-20150246913-A1 | BONE MARROW ON X CHROMOSOME KINASE (BMX) INHIBITORS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2015-09-03 | — | — | US | disclosed |
| US-20150246893-A1 | FUNCTIONALIZED 1,2,4,5-TETRAZINE COMPOUNDS FOR USE IN BIOORTHOGONAL COUPLING REACTIONS | THE GENERAL HOSPITAL CORPORATION (US) | 2015-09-03 | — | — | US | disclosed |
| US-9120757-B2 | Arginine methyltransferase inhibitors and uses thereof | Epizyme, Inc. (US) | 2015-09-01 | — | — | US | disclosed |
| US-20150239937-A1 | PROLINE-LOCKED STAPLED PEPTIDES AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-08-27 | — | — | US | disclosed |
| US-20150238611-A1 | BOLAAMPHIPHILIC COMPOUNDS, COMPOSITIONS AND USES THEREOF | LAUREN SCIENCES LLC | 2015-08-27 | — | — | US | disclosed |
| US-20150241439-A1 | BENZOCYCLOOCTYNE COMPOUNDS AND USES THEREOF | ACADEMIA SINICA (TW) | 2015-08-27 | — | — | US | disclosed |
| EP-2909204-A1 | GSK3 INHIBITORS AND METHODS OF USE THEREOF | The Broad Institute, Inc. (US) | 2015-08-26 | — | — | EP | disclosed |
| EP-2909194-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 (CDK7) | Dana-Farber Cancer Institute, Inc. (US) | 2015-08-26 | — | — | EP | disclosed |
| US-9114176-B2 | Exogenously triggered controlled release materials and uses thereof | SMARTCELLS, INC. (US) | 2015-08-25 | — | — | US | disclosed |
| US-9115053-B2 | Activators of class I histone deacetlyases (HDACS) and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2015-08-25 | — | — | US | disclosed |
| US-20150232615-A1 | Functionalized Polymers | QUIAPEG AB (SE) | 2015-08-20 | — | — | US | disclosed |
| US-20150231251-A1 | COMPOSITIONS AND METHODS FOR TOPICAL DELIVERY OF PROSTAGLANDINS TO SUBCUTANEOUS FAT | TOPOKINE THERAPEUTICS, INC. (US) | 2015-08-20 | — | — | US | disclosed |
| US-9108989-B2 | Inhibitors of fatty acid amide hydrolase | INFINITY PHARMACEUTICALS, INC. (US) | 2015-08-18 | — | — | US | disclosed |
| US-20150225471-A1 | STABILIZED POLYPEPTIDE INSULIN RECEPTOR MODULATORS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-08-13 | — | — | US | disclosed |
| US-20150225438-A1 | SUPRAMETALLOGELS AND USES THEREOF | NATIONAL SCIENCE FOUNDATION | 2015-08-13 | — | — | US | disclosed |
| US-20150225766-A1 | CELL-PERMEABLE PROBES FOR IDENTIFICATION AND IMAGING OF SIALIDASES | ACADEMIA SINICA (TW) | 2015-08-13 | — | — | US | disclosed |
| WO-2015120391-A1 | SUPRAMETALLOGELS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2015-08-13 | — | — | WO | disclosed |
| EP-2321364-B1 | METHODS FOR POLYMER SYNTHESIS | NOVOMER INC (US) | 2015-08-12 | — | — | EP | disclosed |
| US-9102697-B2 | Trioxacarcins and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-08-11 | — | — | US | disclosed |
| WO-2015117053-A1 | DIAMINOPYRIMIDINE BENZENESULFONE DERIVATIVES AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2015-08-06 | — | — | WO | disclosed |
| WO-2015117083-A1 | DIAZEPANE DERIVATIVES AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2015-08-06 | — | — | WO | disclosed |
| WO-2015117087-A1 | USES OF DIAZEPANE DERIVATIVES | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2015-08-06 | — | — | WO | disclosed |
| EP-2797895-B1 | FUNGICIDAL 3-[(1,3-THIAZOL-4-YLMETHOXYIMINO)(PHENYL)METHYL]-2-SUBSTITUTED-1,2,4-OXADIAZOL-5(2H)-ONE DERIVATIVES | BAYER IP GMBH (DE) | 2015-08-05 | — | — | EP | disclosed |
| CN-102014897-B | Compound, compositions and its preparation method | SIGNUM BIOSCIENCES, INC. (US) | 2015-08-05 | — | — | CN | disclosed |
| US-9096594-B2 | Kinase inhibitors and methods of use thereof | THE BROAD INSTITUTE, INC. (US) | 2015-08-04 | — | — | US | disclosed |
| US-9095623-B2 | Terminally-functionalized conjugates and uses thereof | SMARTCELLS, INC. (US) | 2015-08-04 | — | — | US | disclosed |
| US-9095504-B2 | RNA interference in ocular indications | RXI PHARMACEUTICALS CORPORATION | 2015-08-04 | — | — | US | disclosed |
| US-20150211006-A1 | CHIRAL CONTROL | WAVE LIFE SCIENCES USA, INC. | 2015-07-30 | — | — | US | disclosed |
| US-9089579-B2 | Methods and compositions for treating metabolic syndrome | TOPOKINE THERAPEUTICS, INC. (US) | 2015-07-28 | — | — | US | disclosed |
| US-20150203439-A1 | AMINOALCOHOL LIPIDOIDS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2015-07-23 | — | — | US | disclosed |
| US-20150203456-A1 | PYRIMIDINE-2,4,6-TRIONES FOR USE IN THE TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS | CAMBRIA PHARMACEUTICALS DISTRIBUTING TRUST | 2015-07-23 | — | — | US | disclosed |
| WO-2015073746-A9 | 18F LABELING OF PROTEINS USING SORTASES | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2015-07-23 | — | — | WO | disclosed |
| CN-102209532-B | Method for reducing small, dense LDL particles | METABOLEX INC | 2015-07-22 | — | — | CN | disclosed |
| US-20150197506-A1 | NOVEL BENZOPYRAN COMPOUNDS, COMPOSITIONS AND USES THEREOF | OLEMA PHARMACEUTICALS, INC. (US) | 2015-07-16 | — | — | US | disclosed |
| US-20150197480-A9 | GLUCAGON-LIKE PEPTIDE 1 (GLP-1) RECEPTOR MODULATORS AND USES THEREOF IN REGULATING BLOOD GLUCOSE LEVELS | ACADEMIA SINICA (TW) | 2015-07-16 | — | — | US | disclosed |
| US-20150196672-A1 | COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS | LANTHEUS MEDICAL IMAGING, INC. (US) | 2015-07-16 | — | — | US | disclosed |
| EP-2892509-A1 | BOLAAMPHIPHILIC COMPOUNDS, COMPOSITIONS AND USES THEREOF | Lauren Sciences LLC (US) | 2015-07-15 | — | — | EP | disclosed |
| EP-2892508-A1 | BOLAAMPHIPHILIC COMPOUNDS, COMPOSITIONS AND USES THEREOF | Lauren Sciences LLC (US) | 2015-07-15 | — | — | EP | disclosed |
| EP-2892510-A1 | BOLAAMPHIPHILIC COMPOUNDS, COMPOSITIONS AND USES THEREOF | Lauren Sciences LLC (US) | 2015-07-15 | — | — | EP | disclosed |
| EP-2892511-A1 | BOLAAMPHIPHILIC COMPOUNDS, COMPOSITIONS AND USES THEREOF | Lauren Sciences LLC (US) | 2015-07-15 | — | — | EP | disclosed |
| EP-2892512-A1 | BOLAAMPHIPHILIC COMPOUNDS, COMPOSITIONS AND USES THEREOF | Lauren Sciences LLC (US) | 2015-07-15 | — | — | EP | disclosed |
| US-9080171-B2 | Reduced size self-delivering RNAi compounds | RXi Parmaceuticals Corporation (US) | 2015-07-14 | — | — | US | disclosed |
| US-20150191449-A1 | SYNTHESIS OF THIOHYDANTOINS | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2015-07-09 | — | — | US | disclosed |
| WO-2015103583-A1 | MONOBACTAMS AND METHODS OF THEIR SYNTHESIS AND USE | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-07-09 | — | — | WO | disclosed |
| US-20150191417-A1 | ANTI-PROLIFERATIVE COMPOUNDS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2015-07-09 | — | — | US | disclosed |
| US-20150190411-A1 | ACTIVATION OF HISTONE DEACETYLASE 1 (HDAC1) PROTECTS AGAINST DNA DAMAGE AND INCREASES NEURONAL SURVIVAL | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2015-07-09 | — | — | US | disclosed |
| US-20150191432-A1 | PRMT5 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2015-07-09 | — | — | US | disclosed |
| US-9073829-B2 | Synthesis of tetracyclines and intermediates thereto | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-07-07 | — | — | US | disclosed |
| US-9073941-B2 | Compounds and methods for treating tuberculosis infection | ACADEMIA SINICA (TW) | 2015-07-07 | — | — | US | disclosed |
| WO-2015100420-A1 | CORTISTATIN ANALOGUES AND SYNTHESES AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-07-02 | — | — | WO | disclosed |
| WO-2015100331-A2 | PHENAZINE DERIVATIVES AS ANTIMICROBIAL AGENTS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2015-07-02 | — | — | WO | disclosed |
| US-9068006-B2 | Glycated CD59 peptides, their preparation, and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-06-30 | — | — | US | disclosed |
| US-9068013-B2 | Recombinant lectins, binding-site modified lectins and uses thereof | SMART CELLS, INC. (US) | 2015-06-30 | — | — | US | disclosed |
| WO-2015095052-A1 | ISOINDOLIN-1-ONES AS MACROPHAGE MIGRATION INHIBITORY FACTOR (MIF) INHIBITORS | CONTROLLED CHEMICALS, INC. (US) | 2015-06-25 | — | — | WO | disclosed |
| US-20150175651-A1 | NEUROACTIVE STEROIDS, COMPOSITIONS, AND USES THEREOF | SAGE THERAPEUTICS, INC. (US) | 2015-06-25 | — | — | US | disclosed |
| US-20150174260-A1 | AMINE-CONTAINING TRANSFECTION REAGENTS AND METHODS FOR MAKING AND USING SAME | Life Technologies Corporation | 2015-06-25 | — | — | US | disclosed |
| US-20150175540-A1 | ISOINDOLIN-1-ONES AS MACROPHAGE MIGRATION INHIBITORY FACTOR (MIF) INHIBITORS | CONTROLLED CHEMICALS, INC. (US) | 2015-06-25 | — | — | US | disclosed |
| EP-2885311-A1 | CELL-PERMEABLE PROBES FOR IDENTIFICATION AND IMAGING OF SIALIDASES | Academia Sinica (TW) | 2015-06-24 | — | — | EP | disclosed |
| EP-2885416-A1 | LARGE SCALE ENZYMATIC SYNTHESIS OF OLIGOSACCHARIDES | Academia Sinica (TW) | 2015-06-24 | — | — | EP | disclosed |
| US-9061977-B2 | Purification of precursor compound by crystallisation | GE HEALTHCARE LIMITED (GB) | 2015-06-23 | — | — | US | disclosed |
| WO-2015089481-A2 | METHODS TO TREAT LYMPHOPLASMACYTIC LYMPHOMA | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2015-06-18 | — | — | WO | disclosed |
| WO-2015089479-A1 | METHODS TO TREAT LYMPHOPLASMACYTIC LYMPHOMA | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2015-06-18 | — | — | WO | disclosed |
| US-20150166532-A1 | HOST TARGETED INHIBITORS OF DENGUE VIRUS AND OTHER VIRUSES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-06-18 | — | — | US | disclosed |
| US-20150168430-A1 | TRAPPING REAGENTS FOR REACTIVE METABOLITES SCREENING | BIOGEN IDEC MA INC. (US) | 2015-06-18 | — | — | US | disclosed |
| US-20150166594-A1 | MOENOMYCIN ANALOGS, METHODS OF SYNTHESIS, AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-06-18 | — | — | US | disclosed |
| US-20150166517-A1 | COMPOUNDS FOR THE TREATMENT AND PREVENTION OF INFECTIONS | BROWN UNIVERSITY (US) | 2015-06-18 | — | — | US | disclosed |
| US-20150166562-A1 | METHODS AND PRODUCTS RELATED TO PROTOZOAN DISEASE | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2015-06-18 | — | — | US | disclosed |
| EP-2882719-A2 | COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS | Lantheus Medical Imaging, Inc. (US) | 2015-06-17 | — | — | EP | disclosed |
| EP-2882736-A1 | PROCESSES FOR THE PREPARATION OF (S)-3-4-((4-(MORPHOLINOMETHYL) BENZYL)OXY)-1-OXOISOINDOLIN-2-YL) PIPERIDINE-2,6-DIONE AND PHARMACEUTICALLY ACCEPTABLE FORMS THEREOF | Celgene Corporation (US) | 2015-06-17 | — | — | EP | disclosed |
| CN-102781909-B | N-alkoxyamide conjugates as imaging agents | LANTHEUS MEDICAL IMAGING INC | 2015-06-17 | — | — | CN | disclosed |
| CN-104718202-A | Processes for the preparation of (S)-3-4-((4-(morpholinomethyl) benzyl)oxy)-1-oxoisoindolin-2-yl) piperidine-2,6-dione and pharmaceutically acceptable forms thereof | CELGENE CORP | 2015-06-17 | — | — | CN | disclosed |
| WO-2015085113-A1 | METHODS FOR TREATMENT OF WOUND HEALING UTILIZING CHEMICALLY MODIFIED OLIGONUCLEOTIDES | RXI PHARMACEUTICALS CORPORATION (US) | 2015-06-11 | — | — | WO | disclosed |
| US-20150158903-A1 | NEUROACTIVE STEROIDS, COMPOSITIONS, AND USES THEREOF | SAGE THERAPEUTICS, INC. (US) | 2015-06-11 | — | — | US | disclosed |
| US-9050370-B2 | Conjugate based systems for controlled drug delivery | SMARTCELLS, INC. (US) | 2015-06-09 | — | — | US | disclosed |
| US-20150152221-A1 | POLYCARBONATE POLYOL COMPOSITIONS AND METHODS | SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) | 2015-06-04 | — | — | US | disclosed |
| US-20150150668-A1 | UROLOGICAL DEVICE | VYSERA BIOMEDICAL LIMITED (IE) | 2015-06-04 | — | — | US | disclosed |
| EP-2877453-A1 | PROCESS FOR THE PREPARATION OF 4-AMINO-5-FLUORO-3-HALO-6-(SUBSTITUTED)PICOLINATES | Dow AgroSciences LLC (US) | 2015-06-03 | — | — | EP | disclosed |
| US-9045455-B2 | Arginine methyltransferase inhibitors and uses thereof | Epizyme, Inc. (US) | 2015-06-02 | — | — | US | disclosed |
| US-20150148360-A1 | 3,5,N-TRIHYDROXY-ALKANAMIDE AND DERIVATIVES: METHOD FOR MAKING SAME AND USE THEREOF | SIGA TECHNOLOGIES, INC. | 2015-05-28 | — | — | US | disclosed |
| WO-2015077655-A1 | DESFERRITHIOCIN ANALOGS AND USES THEREOF | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2015-05-28 | — | — | WO | disclosed |
| WO-2015077652-A1 | DESAZADESFERRITHIOCIN ANALOGS AND USES THEREOF | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2015-05-28 | — | — | WO | disclosed |
| US-20150147345-A1 | CONJUGATES OF BIOLOGICALLY ACTIVE MOLECULES TO FUNCTIONALIZED POLYMERS | QUIAPEG AB (SE) | 2015-05-28 | — | — | US | disclosed |
| EP-2874994-A2 | 3,5,N-TRIHYDROXY-ALKANAMIDE AND DERIVATIVES: METHOD FOR MAKING SAME AND USE THEREOF | Academia Sinica (TW) | 2015-05-27 | — | — | EP | disclosed |
| CN-104661664-A | Chiral control | WAVE LIFE SCIENCES PTY LTD | 2015-05-27 | — | — | CN | disclosed |
| US-9040584-B2 | Compositions for topical delivery of prostaglandins to subcutaneous fat | TOPOKINE THERAPEUTICS, INC. (US) | 2015-05-26 | — | — | US | disclosed |
| WO-2015073746-A2 | 18F LABELING OF PROTEINS USING SORTASES | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2015-05-21 | — | — | WO | disclosed |
| US-20150140070-A1 | LIPID FORMULATIONS FOR DELIVERY OF MESSENGER RNA | TRANSLATE BIO, INC. | 2015-05-21 | — | — | US | disclosed |
| EP-2872147-A2 | CHIRAL CONTROL | Wave Life Sciences Pte. Ltd. (SG) | 2015-05-20 | — | — | EP | disclosed |
| EP-2872125-A2 | ANTI-PROLIFERATIVE COMPOUNDS AND USES THEREOF | Dana-Farber Cancer Institute, Inc. (US) | 2015-05-20 | — | — | EP | disclosed |
| CN-104640540-A | Enhanced anti-influenza agents coupled with anti-inflammatory activity | ACADEMIA SINICA | 2015-05-20 | — | — | CN | disclosed |
| WO-2015070080-A2 | NUCLEIC ACID NANOSTRUCTURES FOR IN VIVO AGENT DELIVERY | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2015-05-14 | — | — | WO | disclosed |
| US-20150133427-A1 | PRMT5 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2015-05-14 | — | — | US | disclosed |
| EP-2646446-B1 | BROMODOMAIN INHIBITORS AND USES THEREOF | CONSTELLATION PHARMACEUTICALS INC (US) | 2015-05-13 | — | — | EP | disclosed |
| US-20150126721-A1 | METHODS AND INTERMEDIATES FOR THE PREPARATION OF FONDAPARINUX | ACADEMIA SINICA (TW) | 2015-05-07 | — | — | US | disclosed |
| EP-2303888-B1 | COMPOUNDS FOR ANTIMICROBIAL INTERVENTION | HARVARD COLLEGE (US) | 2015-05-06 | — | — | EP | disclosed |
| US-9023848-B2 | Small-molecules as therapeutics | BIONOMICS LIMITED (AU) | 2015-05-05 | — | — | US | disclosed |
| US-9023883-B2 | PRMT1 inhibitors and uses thereof | Epizyme, Inc. (US) | 2015-05-05 | — | — | US | disclosed |
| US-20150119354-A1 | MOENOMYCIN ANALOGS, METHODS OF SYNTHESIS, AND USES THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-04-30 | — | — | US | disclosed |
| WO-2015061467-A1 | LIPID FORMULATIONS FOR DELIVERY OF MESSENGER RNA | SHIRE HUMAN GENETIC THERAPIES, INC. (US) | 2015-04-30 | — | — | WO | disclosed |
| US-20150119561-A1 | CHEMOENZYMATIC METHODS FOR SYNTHESIZING MOENOMYCIN ANALOGS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-04-30 | — | — | US | disclosed |
| EP-2863886-A2 | COMPOSITIONS AND METHODS FOR TOPICAL DELIVERY OF PROSTAGLANDINS TO SUBCUTANEOUS FAT | Topokine Therapeutics, Inc. (US) | 2015-04-29 | — | — | EP | disclosed |
| US-9018244-B2 | Benzopyran compounds, compositions and uses thereof | OLEMA PHARMACEUTICALS, INC. (US) | 2015-04-28 | — | — | US | disclosed |
| US-20150110875-A1 | BOLAAMPHIPHILIC COMPOUNDS, COMPOSITIONS AND USES THEREOF | LAUREN SCIENCES LLC (US) | 2015-04-23 | — | — | US | disclosed |
| US-20150111921-A1 | CORTISTATIN ANALOGUES AND SYNTHESES THEROF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-04-23 | — | — | US | disclosed |
| WO-2015058140-A1 | POLYCYCLIC INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 (CDK7) | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2015-04-23 | — | — | WO | disclosed |
| WO-2015057894-A1 | METHODS FOR TREATING POLYCYSTIC KIDNEY DISEASE AND POLYCYSTIC LIVER DISEASE | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2015-04-23 | — | — | WO | disclosed |
| WO-2015058047-A2 | FLUORINATION OF ORGANIC COMPOUNDS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-04-23 | — | — | WO | disclosed |
| WO-2015057958-A2 | ENTEROBACTIN CONJUGATES AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2015-04-23 | — | — | WO | disclosed |
| US-20150105337-A1 | ENTEROBACTIN CONJUGATES AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2015-04-16 | — | — | US | disclosed |
| US-20150105361-A1 | METHODS FOR TREATING POLYCYSTIC KIDNEY DISEASE AND POLYCYSTIC LIVER DISEASE | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2015-04-16 | — | — | US | disclosed |
| US-20150105317-A1 | GLUCOSE-RESPONSIVE INSULIN CONJUGATES | MERCK SHARP & DOHME LLC | 2015-04-16 | — | — | US | disclosed |
| US-20150104502-A1 | BOLAAMPHIPHILIC COMPOUNDS, COMPOSITIONS AND USES THEREOF | LAUREN SCIENCES LLC | 2015-04-16 | — | — | US | disclosed |
| US-20150105462-A1 | COMPOSITIONS AND METHODS FOR TOPICAL DELIVERY OF PROSTAGLANDINS TO SUBCUTANEOUS FAT | TOPOKINE THERAPEUTICS, INC. (US) | 2015-04-16 | — | — | US | disclosed |
| EP-2858678-A2 | CONJUGATES OF BIOLOGICALLY ACTIVE MOLECULES TO FUNCTIONALIZED POLYMERS | QuiaPEG AB (SE) | 2015-04-15 | — | — | EP | disclosed |
| US-9006487-B2 | Amine-containing lipids and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2015-04-14 | — | — | US | disclosed |
| WO-2015051030-A2 | STABILIZED POLYPEPTIDES AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-04-09 | — | — | WO | disclosed |
| WO-2015051052-A2 | GLUCOSE-RESPONSIVE INSULIN CONJUGATES | MERCK SHARP & DOHME CORP. (US) | 2015-04-09 | — | — | WO | disclosed |
| US-20150099738-A1 | ISOXAZOLINES AS INHIBITORS OF FATTY ACID AMIDE HYDROLASE | INFINITY PHARMACEUTICALS, INC. | 2015-04-09 | — | — | US | disclosed |
| WO-2015050505-A1 | BICYCLIC ALKYNE DERIVATIVES AND USES THEREOF | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2015-04-09 | — | — | WO | disclosed |
| EP-2855558-A2 | POLYCARBONATE POLYOL COMPOSITIONS AND METHODS | Novomer, Inc. (US) | 2015-04-08 | — | — | EP | disclosed |
| WO-2015048121-A1 | VITAMIN C PRODRUGS AND USES THEREOF | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2015-04-02 | — | — | WO | disclosed |
| EP-2852678-A1 | TRAPPING REAGENTS FOR REACTIVE METABOLITES SCREENING | Biogen Idec MA Inc. (US) | 2015-04-01 | — | — | EP | disclosed |
| CN-104487485-A | Polycarbonate polyol compositions and methods | NOVOMER INC | 2015-04-01 | — | — | CN | disclosed |
| US-8993555-B2 | PRMT5 inhibitors and uses thereof | Epizyme, Inc. (US) | 2015-03-31 | — | — | US | disclosed |
| US-8992410-B2 | Urological device | VYSERA BIOMEDICAL LIMITED (IE) | 2015-03-31 | — | — | US | disclosed |
| US-20150086585-A1 | TRITERPENE SAPONINS, METHODS OF SYNTHESIS AND USES THEREOF | MEMORIAL SLOAN KETTERING INST FOR CANCER RES (US) | 2015-03-26 | — | — | US | disclosed |
| EP-2850091-A1 | METHODS AND COMPOUNDS FOR IDENTIFYING GLYCOSYLTRANSFERASE INHIBITORS | President and Fellows of Harvard College (US) | 2015-03-25 | — | — | EP | disclosed |
| EP-2850090-A1 | CHEMOENZYMATIC METHODS FOR SYNTHESIZING MOENOMYCIN ANALOGS | President and Fellows of Harvard College (US) | 2015-03-25 | — | — | EP | disclosed |
| US-8987452-B2 | Synthesis of thiohydantoins | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2015-03-24 | — | — | US | disclosed |
| US-20150078997-A1 | N-ALKOXYAMIDE CONJUGATES AS IMAGING AGENTS | LANTHEUS MEDICAL IMAGING, INC. (US) | 2015-03-19 | — | — | US | disclosed |
| US-20150079618-A1 | METHODS AND COMPOUNDS FOR IDENTIFYING GLYCOSYLTRANSFERASE INHIBITORS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-03-19 | — | — | US | disclosed |
| US-20150072986-A1 | UREA DERIVATIVES AND USES THEREOF | KALA BIO, Inc. | 2015-03-12 | — | — | US | disclosed |
| US-20150071960-A1 | HUMAN iNKT CELL ACTIVATION USING GLYCOLIPIDS WITH ALTERED GLYCOSYL GROUPS | ACADEMIA SINICA (TW) | 2015-03-12 | — | — | US | disclosed |
| WO-2015035337-A1 | HUMAN iNKT CELL ACTIVATION USING GLYCOLIPIDS WITH ALTERED GLYCOSYL GROUPS | ACADEMIA SINICA (TW) | 2015-03-12 | — | — | WO | disclosed |
| US-8975232-B2 | Macrocyclic kinase inhibitors and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-03-10 | — | — | US | disclosed |
| EP-2841066-A1 | ENHANCED ANTI-INFLUENZA AGENTS CONJUGATED WITH ANTI-INFLAMMATORY ACTIVITY | Academia Sinica (TW) | 2015-03-04 | — | — | EP | disclosed |
| US-8969353-B2 | Aminoalcohol lipidoids and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2015-03-03 | — | — | US | disclosed |
| US-20150057297-A1 | HALOFUGINOL DERIVATIVES AND THEIR USE IN COSMETIC AND PHARMACEUTICAL COMPOSITIONS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-02-26 | — | — | US | disclosed |
| US-20150051369-A1 | METHODS FOR POLYMER SYNTHESIS | SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) | 2015-02-19 | — | — | US | disclosed |
| US-8957026-B2 | Beta-catenin targeting peptides and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-02-17 | — | — | US | disclosed |
| US-8956989-B2 | Catalysts and methods for polymer synthesis | NOVOMER, INC. (US) | 2015-02-17 | — | — | US | disclosed |
| US-8957075-B2 | O-GlcNAc transferase inhibitors and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-02-17 | — | — | US | disclosed |
| EP-2834254-A2 | MOENOMYCIN ANALOGS, METHODS OF SYNTHESIS, AND USES THEREOF | President and Fellows of Harvard College (US) | 2015-02-11 | — | — | EP | disclosed |
| US-8952026-B2 | PRMT1 inhibitors and uses thereof | Epizyme, Inc. (US) | 2015-02-10 | — | — | US | disclosed |
| US-8951930-B2 | Catalysts and methods for polymer synthesis | NOVOMER, INC. (US) | 2015-02-10 | — | — | US | disclosed |
| US-20150038506-A1 | BICYCLIC HETEROARYL DERIVATIVES AS MNK1 AND MNK2 MODULATORS AND USES THEREOF | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2015-02-05 | — | — | US | disclosed |
| US-8946188-B2 | Anti-microbial agents and uses thereof | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2015-02-03 | — | — | US | disclosed |
| US-8946109-B2 | Catalysts and methods for polymer synthesis | NOVOMER, INC. (US) | 2015-02-03 | — | — | US | disclosed |
| US-20150031730-A1 | FUNGICIDAL 3-[(1,3-THIAZOL-4-YLMETHOXYIMINO)(PHENYL)METHYL]-2-SUBSTITUTED-1,2,4-OXADIAZOL-5(2H)-ONE DERIVATIVES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-01-29 | — | — | US | disclosed |
| US-20150031943-A1 | UROLOGICAL DEVICE | VYSERA BIOMEDICAL LIMITED (IE) | 2015-01-29 | — | — | US | disclosed |
| WO-2015013635-A2 | INHIBITORS OF TRANSCRIPTION FACTORS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2015-01-29 | — | — | WO | disclosed |
| US-8940501-B2 | Methods for ligation and uses thereof | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2015-01-27 | — | — | US | disclosed |
| US-8940726-B2 | PRMT5 inhibitors and uses thereof | Epizyme, Inc. (US) | 2015-01-27 | — | — | US | disclosed |
| US-8940690-B2 | Synthetic conjugates and uses thereof | NATIONAL INSTITUTES OF HEALTH (NIH) (US) | 2015-01-27 | — | — | US | disclosed |
| US-20150025150-A1 | METHODS AND COMPOSITIONS FOR TREATING METABOLIC SYNDROME | TOPOKINE THERAPEUTICS, INC. (US) | 2015-01-22 | — | — | US | disclosed |
| EP-2822935-A1 | INHIBITORS OF C-JUN-N-TERMINAL KINASE (JNK) | Dana-Farber Cancer Institute, Inc. (US) | 2015-01-14 | — | — | EP | disclosed |
| US-8933207-B2 | Drug-ligand conjugates, synthesis thereof, and intermediates thereto | SMARTCELLS, INC. (US) | 2015-01-13 | — | — | US | disclosed |
| WO-2014153226-A9 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2015-01-08 | — | — | WO | disclosed |
| US-8927551-B2 | Isoxazolines as inhibitors of fatty acid amide hydrolase | INFINITY PHARMACEUTICALS, INC. (US) | 2015-01-06 | — | — | US | disclosed |
| WO-2014210397-A1 | RM2 ANTIGENS AND USE THEREOF | ACADEMIA SINICA (TW) | 2014-12-31 | — | — | WO | disclosed |
| WO-2014210356-A1 | MULTI-TAILED LIPIDS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2014-12-31 | — | — | WO | disclosed |
| WO-2014210564-A1 | GLYCAN CONJUGATES AND USE THEREOF | ACADEMIA SINICA (TW) | 2014-12-31 | — | — | WO | disclosed |
| US-8921508-B2 | Polycarbonate polyol compositions and methods | NOVOMER, INC. (US) | 2014-12-30 | — | — | US | disclosed |
| WO-2014203132-A1 | SUBSTITUTED BENZOPYRAN COMPOUNDS, COMPOSITIONS AND USES THEREOF | OLEMA PHARMACEUTICALS, INC. (US) | 2014-12-24 | — | — | WO | disclosed |
| US-20140371199-A1 | BICYCLIC HETEROCYCLIC DERIVATIVES AS MNK1 AND MNK2 MODULATORS AND USES THEREOF | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2014-12-18 | — | — | US | disclosed |
| US-20140371313-A1 | Cyclohexane-1,3-Diones for Use in the Treatment of Amyotrophic Lateral Sclerosis | CAMBRIA PHARMACEUTICALS DISTRIBUTING TRUST | 2014-12-18 | — | — | US | disclosed |
| WO-2014201127-A2 | UREA DERIVATIVES AND USES THEREOF | KALA PHARMACEUTICALS, INC. (US) | 2014-12-18 | — | — | WO | disclosed |
| US-20140371206-A1 | BROMODOMAIN INHIBITORS AND USES THEREOF | CONSTELLATION PHARMACEUTICALS, INC. (US) | 2014-12-18 | — | — | US | disclosed |
| WO-2014201370-A1 | STABILIZED POLYPEPTIDE INSULIN RECEPTOR MODULATORS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2014-12-18 | — | — | WO | disclosed |
| US-8912304-B2 | Polyol-based polymers | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2014-12-16 | — | — | US | disclosed |
| WO-2014197313-A2 | NOVEL COMPOUNDS AND USES THEREOF | KALA PHARMACEUTICALS, INC. (US) | 2014-12-11 | — | — | WO | disclosed |
| US-8906850-B2 | Crystalline insulin-conjugates | SMARTCELLS, INC. (US) | 2014-12-09 | — | — | US | disclosed |
| US-8907104-B2 | Synthesis of enone intermediate | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2014-12-09 | — | — | US | disclosed |
| US-8906900-B2 | PRMT5 inhibitors and uses thereof | Epizyme, Inc. (US) | 2014-12-09 | — | — | US | disclosed |
| WO-2014193837-A1 | SYNTHESIS OF GALANAL COMPOUNDS AND ANALOGUES THEREOF | ACADEMIA SINICA (TW) | 2014-12-04 | — | — | WO | disclosed |
| WO-2014193832-A2 | GLUCAGON-LIKE PEPTIDE 1 (GLP-1) RECEPTOR MODULATORS AND USES THEREOF IN REGULATING BLOOD GLUCOSE LEVELS | ACADEMIA SINICA (TW) | 2014-12-04 | — | — | WO | disclosed |
| WO-2014194169-A1 | RADIOSYNTHESIS OF TAU RADIOPHARMACEUTICALS | THE GENERAL HOSPITAL CORPORATION (US) | 2014-12-04 | — | — | WO | disclosed |
| EP-2479169-B1 | Synthesis of Enone Intermediate | HARVARD COLLEGE (US) | 2014-12-03 | — | — | EP | disclosed |
| US-20140350104-A1 | METHODS AND COMPOSITIONS FOR REDUCING BODY FAT AND ADIPOCYTES | TOPOKINE THERAPEUTICS, INC. (US) | 2014-11-27 | — | — | US | disclosed |
| US-20140350056-A1 | TRPV1 ANTAGONISTS INCLUDING DIHYDROXY SUBSTITUENT AND USES THEREOF | PURDUE PHARMA L.P. | 2014-11-27 | — | — | US | disclosed |
| WO-2014160200-A9 | RAS INHIBITORS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2014-11-27 | — | — | WO | disclosed |
| US-20140350100-A1 | GLUCAGON-LIKE PEPTIDE 1 (GLP-1) RECEPTOR MODULATORS AND USES THEREOF IN REGULATING BLOOD GLUCOSE LEVELS | ACADEMIA SINICA (TW) | 2014-11-27 | — | — | US | disclosed |
| US-20140350288-A1 | SYNTHESIS OF GALANAL COMPOUNDS AND ANALOGUES THEREOF | ACADEMIA SINICA (TW) | 2014-11-27 | — | — | US | disclosed |
| WO-2014186504-A1 | METHODS AND COMPOSITIONS FOR TOPICAL DELIVERY OF PROSTAGLANDINS TO SUBCUTANEOUS FAT | TOPOKINE THERAPEUTICS, INC. (US) | 2014-11-20 | — | — | WO | disclosed |
| US-20140343246-A1 | CATALYSTS AND METHODS FOR POLYMER SYNTHESIS | SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) | 2014-11-20 | — | — | US | disclosed |
| US-20140342980-A1 | BINDING-SITE MODIFIED LECTINS AND USES THEREOF | SMARTCELLS INC (US) | 2014-11-20 | — | — | US | disclosed |
| US-20140343110-A1 | USES OF 4'-DESFERRITHIOCIN ANALOGS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2014-11-20 | — | — | US | disclosed |
| EP-2802572-A1 | HALOFUGINOL DERIVATIVES AND THEIR USE IN COSMETIC AND PHARMACEUTICAL COMPOSITIONS | President and Fellows of Harvard College (US) | 2014-11-19 | — | — | EP | disclosed |
| US-8889706-B2 | Soluble mTOR complexes and modulators thereof | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2014-11-18 | — | — | US | disclosed |
| US-8889842-B2 | Triterpene saponins, methods of synthesis, and uses thereof | Sloan-Kettering Insititute for Cancer Research (US) | 2014-11-18 | — | — | US | disclosed |
| US-8883834-B2 | Methods and compositions for locally increasing body fat | TOPOKINE THERAPEUTICS, INC. (US) | 2014-11-11 | — | — | US | disclosed |
| WO-2014179567-A2 | METHODS AND COMPOSITIONS FOR TREATING BETA-THALASSEMIA AND SICKLE CELL DISEASE | ACADEMIA SINICA (TW) | 2014-11-06 | — | — | WO | disclosed |
| US-20140328756-A1 | COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS | LANTHEUS MEDICAL IMAGING, INC. (US) | 2014-11-06 | — | — | US | disclosed |
| US-20140329884-A1 | 1,3,5-TRIAZINANE-2,4,6-TRIONE DERIVATIVES AND USES THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2014-11-06 | — | — | US | disclosed |
| WO-2014178954-A1 | PYRAZOLE DERIVATIVES AS ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2014-11-06 | — | — | WO | disclosed |
| WO-2014179562-A1 | 1,3,5-TRIAZINANE-2,4,6-TRIONE DERIVATIVES AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2014-11-06 | — | — | WO | disclosed |
| US-20140329794-A1 | PRMT5 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2014-11-06 | — | — | US | disclosed |
| US-8876800-B2 | Urological device | VYSERA BIOMEDICAL LIMITED (IE) | 2014-11-04 | — | — | US | disclosed |
| US-8877157-B2 | N-alkoxyamide conjugates as imaging agents | LANTHEUS MEDICAL IMAGING, INC. (US) | 2014-11-04 | — | — | US | disclosed |
| US-20140323537-A1 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2014-10-30 | — | — | US | disclosed |
| US-20140323726-A1 | Methods for synthesizing molybdopterin precursor Z derivatives | ALEXION PHARMA INTERNATIONAL SÀRL (CH) | 2014-10-30 | — | — | US | disclosed |
| US-20140323534-A1 | USES OF 3'-DESFERRITHIOCIN ANALOGS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2014-10-30 | — | — | US | disclosed |
| US-20140322309-A1 | ALPHA-AMINOAMIDINE POLYMERS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLO (US) | 2014-10-30 | — | — | US | disclosed |
| EP-2793895-A2 | METHODS AND COMPOSITIONS FOR REDUCING BODY FAT AND ADIPOCYTES | Topokine Therapeutics, Inc. (US) | 2014-10-29 | — | — | EP | disclosed |
| US-8871943-B2 | Process for the preparation of 4-amino-5-fluoro-3-halo-6-(substituted)picolinates | DOW AGROSCIENCES, LLC. (US) | 2014-10-28 | — | — | US | disclosed |
| US-20140315961-A1 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2014-10-23 | — | — | US | disclosed |
| US-20140315904-A1 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2014-10-23 | — | — | US | disclosed |
| EP-2791128-A1 | NOVEL BENZOPYRAN COMPOUNDS, COMPOSITIONS AND USES THEREOF | Olema Pharmaceuticals, Inc. (US) | 2014-10-22 | — | — | EP | disclosed |
| EP-2791210-A1 | ALPHA-AMINOAMIDINE POLYMERS AND USES THEREOF | Massachusetts Institute of Technology (US) | 2014-10-22 | — | — | EP | disclosed |
| EP-2790697-A1 | USES OF 4'-DESFERRITHIOCIN ANALOGS | University of Florida Research Foundation, Inc. (US) | 2014-10-22 | — | — | EP | disclosed |
| CN-104114170-A | Use of 4' -deferthionin analogues | UNIV FLORIDA | 2014-10-22 | — | — | CN | disclosed |
| US-20140308234-A1 | DRUG DELIVERY POLYMER AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2014-10-16 | — | — | US | disclosed |
| WO-2014169073-A1 | DRUG DELIVERY POLYMER AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2014-10-16 | — | — | WO | disclosed |
| US-20140309249-A1 | INHIBITORS OF C-JUN-N-TERMINAL KINASE (JNK) | Dana-Farber Cancer Intitute, Inc. (US) | 2014-10-16 | — | — | US | disclosed |
| WO-2014165792-A2 | MACROLIDES AND METHODS OF THEIR PREPARATION AND USE | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2014-10-09 | — | — | WO | disclosed |
| US-20140303367-A1 | Methods for Synthesizing Molybdopterin Precursor Z Derivatives | ALEXION PHARMA INTERNATIONAL SÀRL (CH) | 2014-10-09 | — | — | US | disclosed |
| EP-2786725-A1 | A luminal valve for placing in a body lumen | Vysera Biomedical Limited (IE) | 2014-10-08 | — | — | EP | disclosed |
| WO-2014160200-A1 | RAS INHIBITORS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2014-10-02 | — | — | WO | disclosed |
| US-20140296243-A1 | BROMODOMAIN INHIBITORS AND USES THEREOF | CONSTELLATION PHARMACEUTICALS, INC. (US) | 2014-10-02 | — | — | US | disclosed |
| WO-2014160441-A1 | NEUROACTIVE STEROIDS, COMPOSITIONS, AND USES THEREOF | SAGE THERAPEUTICS, INC. (US) | 2014-10-02 | — | — | WO | disclosed |
| US-20140296299-A1 | METHODS AND COMPOSITIONS FOR LOCALLY INCREASING BODY FAT | TOPOKINE THERAPEUTICS, INC. (US) | 2014-10-02 | — | — | US | disclosed |
| WO-2014159969-A1 | STAPLED AND STITCHED POLYPEPTIDES AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2014-10-02 | — | — | WO | disclosed |
| WO-2014159392-A1 | BROMODOMAIN BINDING REAGENTS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2014-10-02 | — | — | WO | disclosed |
| US-8846941-B2 | Functionalized polymers | QUIAPEG AB (SE) | 2014-09-30 | — | — | US | disclosed |
| US-8846103-B2 | Exogenously triggered controlled release materials and uses thereof | SMARTCELLS, INC. (US) | 2014-09-30 | — | — | US | disclosed |
| WO-2014153090-A1 | PYRAZOLE DERIVATIVES ASPRMT1 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2014-09-25 | — | — | WO | disclosed |
| WO-2014153226-A1 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2014-09-25 | — | — | WO | disclosed |
| WO-2014153172-A1 | PYRAZOLE DERIVATIVES AS PRMT1 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2014-09-25 | — | — | WO | disclosed |
| WO-2014153208-A1 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2014-09-25 | — | — | WO | disclosed |
| WO-2014153100-A2 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2014-09-25 | — | — | WO | disclosed |
| WO-2014153235-A2 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2014-09-25 | — | — | WO | disclosed |
| WO-2014153214-A1 | ARGININE METHYL TRANSFERASE INHIBTORS AND USES THEREOF | Epizyme, Inc. (US) | 2014-09-25 | — | — | WO | disclosed |
| US-20140288067-A1 | CARM1 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2014-09-25 | — | — | US | disclosed |
| US-20140288129-A1 | PRMT1 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2014-09-25 | — | — | US | disclosed |
| US-20140288105-A1 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2014-09-25 | — | — | US | disclosed |
| US-20140288141-A1 | PRMT1 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2014-09-25 | — | — | US | disclosed |
| US-20140288128-A1 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2014-09-25 | — | — | US | disclosed |
| US-20140288140-A1 | PRMT1 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2014-09-25 | — | — | US | disclosed |
| US-20140288124-A1 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2014-09-25 | — | — | US | disclosed |
| WO-2014144455-A1 | 1 -PHENOXY-3-(ALKYLAMINO)-PROPAN-2-OL DERIVATIVES AS CARM1 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2014-09-18 | — | — | WO | disclosed |
| WO-2014144285-A1 | MEROPENEM DERIVATIVES AND USES THEREOF | KALA PHARMACEUTICALS, INC. (US) | 2014-09-18 | — | — | WO | disclosed |
| WO-2014144659-A1 | PYRAZOLE DERIVATIVES AS PRMT1 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2014-09-18 | — | — | WO | disclosed |
| US-20140274888-A1 | CONJUGATE BASED SYSTEMS FOR CONTROLLED DRUG DELIVERY | SMARTCELLS, INC. (US) | 2014-09-18 | — | — | US | disclosed |
| WO-2014144169-A1 | CARM1 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2014-09-18 | — | — | WO | disclosed |
| WO-2014143808-A1 | HOLLOW PARTICLES ENCAPSULATING A BIOLOGICAL GAS AND METHODS OF USE | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2014-09-18 | — | — | WO | disclosed |
| WO-2014144364-A1 | GAS-FILLED STABILIZED PARTICLES AND METHODS OF USE | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2014-09-18 | — | — | WO | disclosed |
| WO-2014144715-A1 | HSP90-TARGETED CARDIAC IMAGING AND THERAPY | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2014-09-18 | — | — | WO | disclosed |
| WO-2014145887-A1 | BENZIMIDAZOLE DERIVATIVES AND USES THEREOF | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2014-09-18 | — | — | WO | disclosed |
| US-20140275476-A1 | CRYSTALLINE INSULIN-CONJUGATES | SMARTCELLS, INC. (US) | 2014-09-18 | — | — | US | disclosed |
| WO-2014138113-A2 | 1,2-HYDROSILYLATION OF DIENES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2014-09-12 | — | — | WO | disclosed |
| US-20140256622-A1 | EXOGENOUSLY TRIGGERED CONTROLLED RELEASE MATERIALS AND USES THEREOF | SMARTCELLS, INC. (US) | 2014-09-11 | — | — | US | disclosed |
| WO-2014134141-A1 | SYNTHESIS OF ACYCLIC AND CYCLIC AMINES USING IRON-CATALYZED NITRENE GROUP TRANSFER | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2014-09-04 | — | — | WO | disclosed |
| EP-2771319-A1 | AMINO ACID DERIVATIVES FUNCTIONALIZED ON THE N- TERMINAL CAPABLE OF FORMING DRUG INCAPSULATING MICROSPHERES | Massachusetts Institute Of Technology (US) | 2014-09-03 | — | — | EP | disclosed |
| WO-2014130612-A1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | KALA PHARMACEUTICALS, INC. (US) | 2014-08-28 | — | — | WO | disclosed |
| US-20140235657-A1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | KALA PHARMACEUTICALS, INC. (US) | 2014-08-21 | — | — | US | disclosed |
| WO-2014127214-A1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | KALA PHARMACEUTICALS, INC. (US) | 2014-08-21 | — | — | WO | disclosed |
| US-20140235634-A1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | KALA PHARMACEUTICALS, INC. (US) | 2014-08-21 | — | — | US | disclosed |
| US-20140235549-A1 | STABILIZED POLYPEPTIDES AS REGULATORS OF RAB GTPASE FUNCTION | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2014-08-21 | — | — | US | disclosed |
| WO-2014127335-A1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | KALA PHARMACEUTICALS, INC. (US) | 2014-08-21 | — | — | WO | disclosed |
| EP-2766380-A1 | 3,3 DISUBSTITUTED 19-NOR PREGNANE COMPOUNDS, COMPOSITIONS, AND USES THEREOF | Sage Therapeutics, Inc. (US) | 2014-08-20 | — | — | EP | disclosed |
| US-20140228360-A1 | PRMT5 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2014-08-14 | — | — | US | disclosed |
| US-20140228343-A1 | PRMT5 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2014-08-14 | — | — | US | disclosed |
| US-20140221345-A1 | PRMT5 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2014-08-07 | — | — | US | disclosed |
| US-8796261-B2 | Bromodomain inhibitors and uses thereof | CONSTELLATION PHARMACEUTICALS, INC. (US) | 2014-08-05 | — | — | US | disclosed |
| US-20140213515-A1 | MACROCYCLIC INSULIN-DEGRADING ENZYME (IDE) INHIBITORS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2014-07-31 | — | — | US | disclosed |
| US-20140213582-A1 | PRMT5 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2014-07-31 | — | — | US | disclosed |
| US-8778921-B2 | Ansamycin hydroquinone compositions | INFINITY PHARMACEUTICALS, INC. (US) | 2014-07-15 | — | — | US | disclosed |
| US-8778981-B2 | Methods and compositions for locally increasing body fat | TOPOKINE THERAPEUTICS, INC. (US) | 2014-07-15 | — | — | US | disclosed |
| US-8772429-B2 | Biomaterial | VYSERA BIOMEDICAL LIMITED (IE) | 2014-07-08 | — | — | US | disclosed |
| US-8765735-B2 | Isoxazolines as inhibitors of fatty acid amide hydrolase | INFINITY PHARMACEUTICALS, INC. (US) | 2014-07-01 | — | — | US | disclosed |
| US-20140180435-A1 | BIOMATERIAL | VYSERA BIOMEDICAL LIMITED (IE) | 2014-06-26 | — | — | US | disclosed |
| WO-2014100764-A2 | METHODS OF INHIBITING PRMT5 | Epizyme, Inc. (US) | 2014-06-26 | — | — | WO | disclosed |
| WO-2014100734-A1 | PRMT5 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2014-06-26 | — | — | WO | disclosed |
| WO-2014100716-A1 | PRMT5 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2014-06-26 | — | — | WO | disclosed |
| WO-2014100730-A1 | PRMT5 INHIBITORS CONTAINING A DIHYDRO- OR TETRAHYDROISOQUINOLINE AND USES THEREOF | Epizyme, Inc. (US) | 2014-06-26 | — | — | WO | disclosed |
| WO-2014100719-A2 | PRMT5 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2014-06-26 | — | — | WO | disclosed |
| WO-2014100695-A1 | PRMT5 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2014-06-26 | — | — | WO | disclosed |
| US-20140179929-A1 | SYNTHESIS OF ENONE INTERMEDIATE | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2014-06-26 | — | — | US | disclosed |
| US-20140171617-A1 | CATALYSTS AND METHODS FOR POLYMER SYNTHESIS | NOVOMER, INC. (US) | 2014-06-19 | — | — | US | disclosed |
| EP-2741855-A1 | CATALYSTS AND METHODS FOR POLYMER SYNTHESIS | Novomer, Inc. (US) | 2014-06-18 | — | — | EP | disclosed |
| US-20140163238-A1 | SYNTHESIS OF TETRACYCLINES AND ANALOGUES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2014-06-12 | — | — | US | disclosed |
| WO-2014088519-A1 | COMPOUNDS INCLUDING MAP KINASE INTERACTING KINASES 1 AND 2 (MNK1 AND MNK2) MODULATORS AND ABL AND ABL (T315I) INHIBITORS, AND USES THEREOF | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (A*STAR) (SG) | 2014-06-12 | — | — | WO | disclosed |
| US-20140163079-A1 | DIPHOSPHATE MIMETICS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2014-06-12 | — | — | US | disclosed |
| EP-2337522-B1 | ESOPHAGEAL VALVE | VYSERA BIOMEDICAL LTD (IE) | 2014-06-11 | — | — | EP | disclosed |
| EP-2331017-B1 | ESOPHAGEAL VALVE | VYSERA BIOMEDICAL LTD (IE) | 2014-06-11 | — | — | EP | disclosed |
| WO-2014085791-A2 | COMPOSITIONS AND USES THEREOF FOR TREATING MULTIPLE MYELOMA | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2014-06-05 | — | — | WO | disclosed |
| WO-2014082065-A1 | TRIOXACARCINS, TRIOXACARCIN-ANTIBODY CONJUGATES, AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2014-05-30 | — | — | WO | disclosed |
| WO-2014081941-A1 | METHODS AND COMPOSITIONS FOR LOCALLY INCREASING BODY FAT | TOPOKINE THERAPEUTICS, INC. (US) | 2014-05-30 | — | — | WO | disclosed |
| EP-2734510-A2 | ACTIVATORS OF CLASS I HISTONE DEACETLYASES (HDACS) AND USES THEREOF | Massachusetts Institute Of Technology (US) | 2014-05-28 | — | — | EP | disclosed |
| US-20140142075-A1 | METHODS AND COMPOSITIONS FOR LOCALLY INCREASING BODY FAT | TOPOKINE THERAPEUTICS, INC. (US) | 2014-05-22 | — | — | US | disclosed |
| WO-2014078652-A1 | HEAVY ATOM LABELED NUCLEOSIDES, NUCLEOTIDES, AND NUCLEIC ACID POLYMERS, AND USES THEREOF | ZS GENETICS, INC. (US) | 2014-05-22 | — | — | WO | disclosed |
| US-20140135287-A1 | HYPERFORIN ANALOGS, METHODS OF SYNTHESIS, AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2014-05-15 | — | — | US | disclosed |
| US-20140135316-A1 | BROMODOMAIN INHIBITORS AND USES THEREOF | CONSTELLATION PHARMACEUTICALS, INC. (US) | 2014-05-15 | — | — | US | disclosed |
| US-8722939-B2 | Cyclohexane-1,3-diones for use in the treatment of amyotrophic lateral sclerosis | NORTHWESTERN UNIVERSITY (US) | 2014-05-13 | — | — | US | disclosed |
| WO-2014071247-A1 | PYRROL-1 -YL BENZOIC ACID DERIVATES USEFUL AS MYC INHIBITORS | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2014-05-08 | — | — | WO | disclosed |
| EP-2726467-A2 | MACROCYCLIC INSULIN-DEGRADING ENZYME (IDE) INHIBITORS AND USES THEREOF | President and Fellows of Harvard College (US) | 2014-05-07 | — | — | EP | disclosed |
| US-8715621-B2 | Radical polarizing agents for dynamic nuclear polarization | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2014-05-06 | — | — | US | disclosed |
| US-20140121159-A1 | TERMINALLY–FUNCTIONALIZED CONJUGATES AND USES THEREOF | SMARTCELLS, INC. (US) | 2014-05-01 | — | — | US | disclosed |
| US-20140121183-A1 | INHIBITORS OF FATTY ACID AMIDE HYDROLASE | INFINITY PHARMACEUTICALS, INC. (US) | 2014-05-01 | — | — | US | disclosed |
| WO-2014063068-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 (CDK7) | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2014-04-24 | — | — | WO | disclosed |
| WO-2014060575-A2 | PROCESS FOR THE ENANTIOSELECTIVE SYNTHESIS OF A TETRAHYDROBENZAZEPINE COMPOUND | MEDICHEM S.A. (ES) | 2014-04-24 | — | — | WO | disclosed |
| WO-2014062852-A2 | THIOHYDANTOIN DERIVATIVES AND USES THEREOF | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2014-04-24 | — | — | WO | disclosed |
| WO-2014063054-A1 | BONE MARROW ON X CHROMOSOME KINASE (BMX) INHIBITORS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2014-04-24 | — | — | WO | disclosed |
| WO-2014063061-A1 | HYDROPHOBICALLY TAGGED SMALL MOLECULES AS INDUCERS OF PROTEIN DEGRADATION | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2014-04-24 | — | — | WO | disclosed |
| US-20140113950-A1 | INTERFERENCE IN DERMAL AND FIBROTIC INDICATIONS | RXI PHARMACEUTICALS CORPORATION (US) | 2014-04-24 | — | — | US | disclosed |
| EP-2721031-A2 | BROMODOMAIN INHIBITORS AND USES THEREOF | Constellation Pharmaceuticals, Inc. (US) | 2014-04-23 | — | — | EP | disclosed |
| WO-2014059383-A1 | GSK3 INHIBITORS AND METHODS OF USE THEREOF | THE BROAD INSTITUTE, INC. (US) | 2014-04-17 | — | — | WO | disclosed |
| US-20140107141-A1 | KINASE INHIBITORS AND METHODS OF USE THEREOF | THE GENERAL HOSPITAL CORPORATION D/B/A MASSACHUSETTS GENERAL HOSPITAL (US) | 2014-04-17 | — | — | US | disclosed |
| WO-2014055564-A1 | STABILIZED POLYPEPTIDE INSULIN RECEPTOR MODULATORS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2014-04-10 | — | — | WO | disclosed |
| US-20140088104-A1 | NOVEL SMALL-MOLECULES AS THERAPEUTICS | BIONOMICS LIMITED (AU) | 2014-03-27 | — | — | US | disclosed |
| WO-2014047662-A2 | INDAZOLE DERIVATIVES AND USES THEREOF | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2014-03-27 | — | — | WO | disclosed |
| US-8673020-B2 | Esophageal valve device for placing in the cardia | VYSERA BIOMEDICAL LIMITED (IE) | 2014-03-18 | — | — | US | disclosed |
| WO-2014039500-A1 | BOLAAMPHIPHILIC COMPOUNDS, COMPOSITIONS AND USES THEREOF | LAUREN SCIENCES LLC (US) | 2014-03-13 | — | — | WO | disclosed |
| WO-2014039502-A1 | BOLAAMPHIPHILIC COMPOUNDS, COMPOSITIONS AND USES THEREOF | LAUREN SCIENCES LLC (US) | 2014-03-13 | — | — | WO | disclosed |
| WO-2014039503-A1 | BOLAAMPHIPHILIC COMPOUNDS, COMPOSITIONS AND USES THEREOF | LAUREN SCIENCES LLC (US) | 2014-03-13 | — | — | WO | disclosed |
| WO-2014039501-A1 | BOLAAMPHIPHILIC COMPOUNDS, COMPOSITIONS AND USES THEREOF | LAUREN SCIENCES LLC (US) | 2014-03-13 | — | — | WO | disclosed |
| WO-2014039504-A1 | BOLAAMPHIPHILIC COMPOUNDS, COMPOSITIONS AND USES THEREOF | LAUREN SCIENCES LLC (US) | 2014-03-13 | — | — | WO | disclosed |
| WO-2014039493-A1 | BOLAAMPHIPHILIC COMPOUNDS, COMPOSITIONS AND USES THEREOF | LAUREN SCIENCES LLC (US) | 2014-03-13 | — | — | WO | disclosed |
| WO-2014036595-A1 | COMPOUNDS AND METHODS FOR TREATING DISEASES OR CONDITIONS ASSOCIATED WITH THE CENTRAL NERVOUS SYSTEM AND/OR NEURITE OUTGROWTH | BIONOMICS LIMITED (AU) | 2014-03-13 | — | — | WO | disclosed |
| EP-2705039-A2 | BROMODOMAIN INHIBITORS AND USES THEREOF | Constellation Pharmaceuticals, Inc. (US) | 2014-03-12 | — | — | EP | disclosed |
| WO-2014031498-A1 | CELL-PERMEABLE PROBES FOR IDENTIFICATION AND IMAGING OF SIALIDASES | ACADEMIA SINICA (TW) | 2014-02-27 | — | — | WO | disclosed |
| US-20140058106-A1 | SYSTEM FOR FLUORINATING ORGANIC COMPOUNDS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2014-02-27 | — | — | US | disclosed |
| WO-2014031602-A1 | LARGE SCALE ENZYMATIC SYNTHESIS OF OLIGOSACCHARIDES | ACADEMIA SINICA (TW) | 2014-02-27 | — | — | WO | disclosed |
| US-8658677-B2 | Pyridyl-2-methylamino compounds, compositions and uses thereof | ARIA NEUROSCIENCES INC. (US) | 2014-02-25 | — | — | US | disclosed |
| US-20140051701-A1 | METHODS OF TREATING A DISEASE OR CONDITION OF THE CENTRAL NERVOUS SYSTEM | BIONOMICS LIMITED (AU) | 2014-02-20 | — | — | US | disclosed |
| US-20140051127-A1 | LARGE SCALE ENZYMATIC SYNTHESIS OF OLIGOSACCHARIDES | ACADEMIA SINICA (TW) | 2014-02-20 | — | — | US | disclosed |
| US-20140046008-A1 | POLYCARBONATE POLYOL COMPOSITIONS AND METHODS | NOVOMER, INC. (US) | 2014-02-13 | — | — | US | disclosed |
| WO-2014025978-A1 | PROCESSES FOR THE PREPARATION OF (S)-3-4-((4-(MORPHOLINOMETHYL) BENZYL)OXY)-1-OXOISOINDOLIN-2-YL) PIPERIDINE-2,6-DIONE AND PHARMACEUTICALLY ACCEPTABLE FORMS THEREOF | CELGENE CORPORATION (US) | 2014-02-13 | — | — | WO | disclosed |
| US-20140045933-A1 | METHODS AND COMPOSITIONS FOR TREATING METABOLIC SYNDROME | TERAKINE THERAPEUTICS, INC. (US) | 2014-02-13 | — | — | US | disclosed |
| US-20140046058-A1 | PROCESSES FOR THE PREPARATION OF (S)-3-(4-((4-(MORPHOLINOMETHYL)BENZYL)OXY)-1-OXOISOINDOLIN-2-YL)PIPERIDINE-2,6-DIONE AND PHARMACEUTICALLY ACCEPTABLE FORMS THEREOF | CELGENE CORPORATION (US) | 2014-02-13 | — | — | US | disclosed |
| WO-2014026079-A2 | COMPOSITIONS, METHODS, AND SYSTEMS OF THE SYNTHESIS AND USE OF IMAGING AGENTS | LANTHEUS MEDICAL IMAGING, INC. (US) | 2014-02-13 | — | — | WO | disclosed |
| EP-2693879-A2 | MIGRASTATINS AND USES THEREOF | Sloan Kettering Institute For Cancer Research (US) | 2014-02-12 | — | — | EP | disclosed |
| US-8648198-B2 | Phenylethanolamine-based NMDA receptor antagonists | COLD SPRING HARBOR LABORATORY (US) | 2014-02-11 | — | — | US | disclosed |
| EP-2691396-A2 | ENOPEPTINS, USES THEREOF, AND METHODS OF SYNTHESIS THERETO | Brown University (US) | 2014-02-05 | — | — | EP | disclosed |
| EP-2691443-A2 | CONJUGATED LIPOMERS AND USES THEREOF | Massachusetts Institute Of Technology (US) | 2014-02-05 | — | — | EP | disclosed |
| US-20140030278-A1 | CONJUGATES OF TUMOR NECROSIS FACTOR INHIBITORS TO FUNCTIONALIZED POLYMERS | QUIAPEG AB (SE) | 2014-01-30 | — | — | US | disclosed |
| WO-2014018502-A1 | PROCESS FOR THE PREPARATION OF 4-AMINO-5-FLUORO-3-HALO-6-(SUBSTITUTED)PICOLINATES | DOW AGROSCIENCES LLC (US) | 2014-01-30 | — | — | WO | disclosed |
| US-20140031556-A1 | PROCESS FOR THE PREPARATION OF 4-AMINO-5-FLUORO-3-HALO-6-(SUBSTITUTED)PICOLINATES | DOW AGROSCIENCES LLC (US) | 2014-01-30 | — | — | US | disclosed |
| WO-2014014814-A1 | COMPOUNDS FOR THE TREATMENT AND PREVENTION OF INFECTIONS | BROWN UNIVERSITY (US) | 2014-01-23 | — | — | WO | disclosed |
| US-20140024705-A1 | MIGRASTATINS AND USES THEREOF | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2014-01-23 | — | — | US | disclosed |
| US-20140024056-A1 | SURROGATES OF POST-TRANSLATIONALLY MODIFIED PROTEINS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2014-01-23 | — | — | US | disclosed |
| WO-2014015235-A2 | 3,5,N-TRIHYDROXY-ALKANAMIDE AND DERIVATIVES: METHOD FOR MAKING SAME AND USE THEREOF | ACADEMIA SINICA (TW) | 2014-01-23 | — | — | WO | disclosed |
| US-20140024611-A1 | ANTI-MICROBIAL AGENTS AND USES THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2014-01-23 | — | — | US | disclosed |
| US-8633123-B2 | Catalysts and methods for polymer synthesis | NOVOMER, INC. (US) | 2014-01-21 | — | — | US | disclosed |
| US-20140018538-A1 | HIGH-VALENT PALLADIUM FLUORIDE COMPLEXES AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2014-01-16 | — | — | US | disclosed |
| WO-2014012081-A2 | CHIRAL CONTROL | ONTORII, INC. (US) | 2014-01-16 | — | — | WO | disclosed |
| WO-2014012014-A1 | METHODS AND PRODUCTS RELATED TO PROTOZOAN DISEASE | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2014-01-16 | — | — | WO | disclosed |
| WO-2014011713-A2 | ANTI-PROLIFERATIVE COMPOUNDS AND USES THEREOF | DANA-FARBER CANCER INSTITUE, INC. (US) | 2014-01-16 | — | — | WO | disclosed |
| US-8629125-B2 | Inhibitors of fatty acid amide hydrolase | Infinty Pharmaceuticals, Inc. (US) | 2014-01-14 | — | — | US | disclosed |
| US-20140011979-A1 | STITCHED POLYPEPTIDES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2014-01-09 | — | — | US | disclosed |
| US-20140011971-A1 | IRON COMPLEXES AND METHODS FOR POLYMERIZATION | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2014-01-09 | — | — | US | disclosed |
| EP-2681198-A1 | NOVEL SMALL-MOLECULES AS THERAPEUTICS | Bionomics Limited (AU) | 2014-01-08 | — | — | EP | disclosed |
| EP-2680842-A1 | METHODS OF TREATING A DISEASE OR CONDITION OF THE CENTRAL NERVOUS SYSTEM | Bionomics Limited (AU) | 2014-01-08 | — | — | EP | disclosed |
| US-8623345-B2 | Terminally-functionalized conjugates and uses thereof | Smartcells (US) | 2014-01-07 | — | — | US | disclosed |
| US-20140005169-A1 | BROMODOMAIN INHIBITORS AND USES THEREOF | CONSTELLATION PHARMACEUTICALS (US) | 2014-01-02 | — | — | US | disclosed |
| US-20140005118-A1 | BETA-CATENIN TARGETING PEPTIDES AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2014-01-02 | — | — | US | disclosed |
| WO-2013192517-A2 | COMPOUNDS FOR TREATING INFECTIOUS DISEASES | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2013-12-27 | — | — | WO | disclosed |
| US-20130345786-A1 | VALVE DEVICE | VYSERA BIOMEDICAL LIMITED (IE) | 2013-12-26 | — | — | US | disclosed |
| US-20130345223-A9 | COMPOUNDS AND METHODS FOR TREATING TUBERCULOSIS INFECTION | ACADEMIA SINICA (TW) | 2013-12-26 | — | — | US | disclosed |
| EP-2675278-A1 | METHODS FOR SYNTHESIZING MOLYBDOPTERIN PRECURSOR Z DERIVATIVES | Alexion Pharma International SARL (CH) | 2013-12-25 | — | — | EP | disclosed |
| WO-2013188792-A2 | NEUROACTIVE STEROIDS, COMPOSITIONS, AND USES THEREOF | SAGE THERAPEUTICS, INC. (US) | 2013-12-19 | — | — | WO | disclosed |
| WO-2013186632-A2 | CONJUGATES OF BIOLOGICALLY ACTIVE MOLECULES TO FUNCTIONALIZED POLYMERS | QUIAPEG AB (SE) | 2013-12-19 | — | — | WO | disclosed |
| EP-2673293-A2 | SURROGATES OF POST-TRANSLATIONALLY MODIFIED PROTEINS AND USES THEREOF | President and Fellows of Harvard College (US) | 2013-12-18 | — | — | EP | disclosed |
| WO-2013184564-A1 | METHODS AND INTERMEDIATES FOR THE PREPARATION OF FONDAPARINUX | ACADEMIA SINICA (TW) | 2013-12-12 | — | — | WO | disclosed |
| EP-2350053-B1 | Modulators of MTOR Complexes | WHITEHEAD BIOMEDICAL INST (US) | 2013-12-11 | — | — | EP | disclosed |
| US-8604004-B2 | Moenomycin analogs, methods of synthesis, and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2013-12-10 | — | — | US | disclosed |
| US-8603529-B2 | Polynucleotide aptamer-based cross-linked materials and uses thereof | SMARTCELLS, INC. (US) | 2013-12-10 | — | — | US | disclosed |
| US-8604155-B2 | Polycarbonate polyol compositions and methods | NOVOMER, INC. (US) | 2013-12-10 | — | — | US | disclosed |
| US-20130324702-A1 | RECOMBINANT LECTINS, BINDING-SITE MODIFIED LECTINS AND USES THEREOF | SMARTCELLS, INC. | 2013-12-05 | — | — | US | disclosed |
| US-8598148-B2 | Synthesis of tetracyclines and analogues thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2013-12-03 | — | — | US | disclosed |
| US-8598342-B2 | Methods and compounds for antimicrobial intervention | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2013-12-03 | — | — | US | disclosed |
| WO-2013177293-A1 | TRAPPING REAGENTS FOR REACTIVE METABOLITES SCREENING | BIOGEN IDEC MA INC. (US) | 2013-11-28 | — | — | WO | disclosed |
| WO-2013177546-A2 | POLYCARBONATE POLYOL COMPOSITIONS AND METHODS | NOVOMER, INC. (US) | 2013-11-28 | — | — | WO | disclosed |
| EP-2665481-A2 | METHODS AND COMPOSITIONS FOR TREATING METABOLIC SYNDROME | Terakine Therapeutics, Inc. (US) | 2013-11-27 | — | — | EP | disclosed |
| US-8592377-B2 | Stitched polypeptides | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2013-11-26 | — | — | US | disclosed |
| US-20130310559-A1 | ISOPRENYL COMPOUNDS AND METHODS THEREOF | SIGNUM BIOSCIENCES, INC. (US) | 2013-11-21 | — | — | US | disclosed |
| US-20130302401-A1 | POLY(BETA-AMINO ALCOHOLS), THEIR PREPARATION, AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2013-11-14 | — | — | US | disclosed |
| US-8580969-B2 | Synthesis of enone intermediate | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2013-11-12 | — | — | US | disclosed |
| WO-2013160728-A1 | DUAL TARGETING COMPOUNDS FOR THE TREATMENT OF ALZHEIMER'S DISEASE | ALMA MATER STUDIORUM - UNIVERSITA' DI BOLOGNA (IT) | 2013-10-31 | — | — | WO | disclosed |
| US-20130289086-A1 | Aminopyrrolidinone Derivatives and Uses Thereof | DUGGAN MARK E (US) | 2013-10-31 | — | — | US | disclosed |
| EP-2655321-A1 | PURIFICATION OF PRECURSOR COMPOUND BY CRYSTALLISATION | GE Healthcare UK Limited (GB) | 2013-10-30 | — | — | EP | disclosed |
| US-8569376-B2 | Methods and compositions for reducing body fat and adipocytes | TOPOKINE THERAPEUTICS, INC. (US) | 2013-10-29 | — | — | US | disclosed |
| US-20130281708-A1 | Process for the Production of 2-Amino-5-Fluorothiazole | TAKEDA CALIFORNIA, INC. (US) | 2013-10-24 | — | — | US | disclosed |
| EP-2651448-A2 | FUNCTIONALIZED POLYMERS | QuiaPEG AB (SE) | 2013-10-23 | — | — | EP | disclosed |
| WO-2013154778-A1 | HOST TARGETED INHIBITORS OF DENGUE VIRUS AND OTHER VIRUSES | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2013-10-17 | — | — | WO | disclosed |
| WO-2013155375-A1 | ENHANCED ANTI-INFLUENZA AGENTS CONJUGATED WITH ANTI-INFLAMMATORY ACTIVITY | ACADEMIA SINICA (TW) | 2013-10-17 | — | — | WO | disclosed |
| US-20130274507-A1 | PROCESS SIMPLIFICATION FOR PRECURSOR COMPOUND | GE HEALTHCARE LIMITED (GB) | 2013-10-17 | — | — | US | disclosed |
| US-20130274229-A1 | ENHANCED ANTI-INFLUENZA AGENTS CONJUGATED WITH ANTI-INFLAMMATORY ACTIVITY | ACADEMIA SINICA (TW) | 2013-10-17 | — | — | US | disclosed |
| US-20130267730-A1 | PURIFICIATION OF PRECURSOR COMPOUND BY CRYSTALLISATION | GE HEALTHCARE LIMITED (GB) | 2013-10-10 | — | — | US | disclosed |
| WO-2013151697-A1 | METHODS AND COMPOUNDS FOR IDENTIFYING GLYCOSYLTRANSFERASE INHIBITORS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2013-10-10 | — | — | WO | disclosed |
| WO-2013152279-A1 | CHEMOENZYMATIC METHODS FOR SYNTHESIZING MOENOMYCIN ANALOGS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2013-10-10 | — | — | WO | disclosed |
| WO-2013152277-A2 | MOENOMYCIN ANALOGS, METHODS OF SYNTHESIS, AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2013-10-10 | — | — | WO | disclosed |
| EP-2646446-A2 | BROMODOMAIN INHIBITORS AND USES THEREOF | Constellation Pharmaceuticals, Inc. (US) | 2013-10-09 | — | — | EP | disclosed |
| EP-2646411-A1 | PREPARATION OF PET PRECURSOR | GE Healthcare UK Limited (GB) | 2013-10-09 | — | — | EP | disclosed |
| US-20130253005-A1 | SMALL MOLECULE INHIBITORS OF USP1 DEUBIQUITINATING ENZYME ACTIVITY | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2013-09-26 | — | — | US | disclosed |
| EP-2640700-A1 | AMINE-CONTAINING TRANSFECTION REAGENTS AND METHODS FOR MAKING AND USING SAME | Life Technologies Corporation (US) | 2013-09-25 | — | — | EP | disclosed |
| WO-2013138376-A1 | RADICAL POLARIZING AGENTS FOR DYNAMIC NUCLEAR POLARIZATION | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2013-09-19 | — | — | WO | disclosed |
| US-20130243698-A1 | RADICAL POLARIZING AGENTS FOR DYNAMIC NUCLEAR POLARIZATION | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2013-09-19 | — | — | US | disclosed |
| US-20130244864-A1 | POLYCARBONATE POLYOL COMPOSITIONS AND METHODS | NOVOMER, INC. (US) | 2013-09-19 | — | — | US | disclosed |
| US-20130245307-A1 | PREPARATION OF PET PRECURSOR | GE HEALTHCARE LIMITED (GB) | 2013-09-19 | — | — | US | disclosed |
| US-8536293-B2 | Biomaterial | VYSERA BIOMEDICAL LIMITED (IE) | 2013-09-17 | — | — | US | disclosed |
| US-8530456-B2 | Sonic hedgehog modulators | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2013-09-10 | — | — | US | disclosed |
| US-20130224211-A1 | GLYCATED CD59 PEPTIDES, THEIR PREPARATION, AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2013-08-29 | — | — | US | disclosed |
| US-20130225821-A1 | SYNTHESIS OF THIOHYDANTOINS | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2013-08-29 | — | — | US | disclosed |
| US-20130217886-A1 | SYNTHESIS OF ENONE INTERMEDIATE | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2013-08-22 | — | — | US | disclosed |
| US-8500821-B2 | Esophageal valve device for placing in the cardia | VYSERA BIOMEDICAL LIMITED (IE) | 2013-08-06 | — | — | US | disclosed |
| US-20130196948-A1 | POLYMERS FOR BIOMATERIALS AND THERAPEUTICS | MASSACHUSETTS INSITUTE OF TECHNOLOGY (US) | 2013-08-01 | — | — | US | disclosed |
| US-20130190475-A1 | DRUG-LIGAND CONJUGATES, SYNTHESIS THEREOF, AND INTERMEDIATES THERETO | SMARTCELLS, INC. (US) | 2013-07-25 | — | — | US | disclosed |
| EP-2616513-A2 | CATALYSTS AND METHODS FOR POLYMER SYNTHESIS | Novomer, Inc. (US) | 2013-07-24 | — | — | EP | disclosed |
| WO-2013106702-A1 | HALOFUGINOL DERIVATIVES AND THEIR USE IN COSMETIC AND PHARMACEUTICAL COMPOSITIONS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2013-07-18 | — | — | WO | disclosed |
| US-8486921-B2 | Synthesis of tetracyclines and analogues thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2013-07-16 | — | — | US | disclosed |
| US-20130178429-A1 | MACROCYCLIC KINASE INHIBITORS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2013-07-11 | — | — | US | disclosed |
| US-20130178445-A1 | Novel Benzopyran Compounds, Compositions and Uses Thereof | OLEMA PHARMACEUTICALS, INC. (US) | 2013-07-11 | — | — | US | disclosed |
| US-20130178525-A1 | METHODS AND COMPOSITIONS FOR REDUCING BODY FAT AND ADIPOCYTES | TOPOKINE THERAPEUTICS, INC. (US) | 2013-07-11 | — | — | US | disclosed |
| CN-103201034-A | Catalysts and methods for polymer synthesis | NOVOMER INC | 2013-07-10 | — | — | CN | disclosed |
| US-20130172524-A1 | CATALYSTS AND METHODS FOR POLYMER SYNTHESIS | NOVOMER, INC. (US) | 2013-07-04 | — | — | US | disclosed |
| EP-2142562-B1 | STITCHED POLYPEPTIDES | HARVARD COLLEGE (US) | 2013-07-03 | — | — | EP | disclosed |
| EP-2609135-A2 | POLY(BETA-AMINO ALCOHOLS), THEIR PREPARATION, AND USES THEREOF | Massachusetts Institute Of Technology (US) | 2013-07-03 | — | — | EP | disclosed |
| US-20130165473-A1 | Azaquinolinone Derivatives and Uses Thereof | ASTRAZENECA AB (SE) | 2013-06-27 | — | — | US | disclosed |
| WO-2013096429-A2 | METHODS AND COMPOSITIONS FOR REDUCING BODY FAT AND ADIPOCYTES | TOPOKINE THERAPEUTICS, INC. (US) | 2013-06-27 | — | — | WO | disclosed |
| EP-2606056-A2 | HIGH-VALENT PALLADIUM FLUORIDE COMPLEXES AND USES THEREOF | President and Fellows of Harvard College (US) | 2013-06-26 | — | — | EP | disclosed |
| US-8470956-B2 | Polycarbonate polyol compositions and methods | NOVOMER, INC. (US) | 2013-06-25 | — | — | US | disclosed |
| WO-2013090766-A1 | USES OF 3'-DESFERRITHIOCIN ANALOGS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2013-06-20 | — | — | WO | disclosed |
| WO-2013090921-A1 | NOVEL BENZOPYRAN COMPOUNDS, COMPOSITIONS AND USES THEREOF | OLEMA PHARMACEUTICALS, INC. (US) | 2013-06-20 | — | — | WO | disclosed |
| US-20130158021-A1 | AMINO ACID-, PEPTIDE-AND POLYPEPTIDE-LIPIDS, ISOMERS, COMPOSITIONS, AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2013-06-20 | — | — | US | disclosed |
| WO-2013090861-A1 | ALPHA-AMINOAMIDINE POLYMERS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2013-06-20 | — | — | WO | disclosed |
| WO-2013090750-A1 | USES OF 4'-DESFERRITHIOCIN ANALOGS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2013-06-20 | — | — | WO | disclosed |
| US-20130158037-A1 | COMPOUNDS AND METHODS FOR TREATING TUBERCULOSIS INFECTION | ACADEMIA SINICA (TW) | 2013-06-20 | — | — | US | disclosed |
| US-20130149244-A1 | COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS | LANTHEUS MEDICAL IMAGING, INC. (US) | 2013-06-13 | — | — | US | disclosed |
| US-20130150314-A1 | TRIOXACARCINS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2013-06-13 | — | — | US | disclosed |
| US-8461128-B2 | Anti-microbial agents and uses thereof | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2013-06-11 | — | — | US | disclosed |
| US-8461343-B2 | Synthesis of thiohydantoins | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2013-06-11 | — | — | US | disclosed |
| US-8461204-B2 | Cysteinyl compounds, compositions and methods of use | SIGNUM BIOSCIENCES, INC. (US) | 2013-06-11 | — | — | US | disclosed |
| US-20130144031-A1 | CATALYSTS AND METHODS FOR POLYMER SYNTHESIS | NOVOMER, INC. (US) | 2013-06-06 | — | — | US | disclosed |
| US-20130144032-A1 | CATALYSTS AND METHODS FOR POLYMER SYNTHESIS | NOVOMER, INC. (US) | 2013-06-06 | — | — | US | disclosed |
| US-20130144033-A1 | CATALYSTS AND METHODS FOR POLYMER SYNTHESIS | NOVOMER, INC. (US) | 2013-06-06 | — | — | US | disclosed |
| EP-2598522-A2 | RECOMBINANT LECTINS, BINDING-SITE MODIFIED LECTINS AND USES THEREOF | Smartcells, Inc. (US) | 2013-06-05 | — | — | EP | disclosed |
| EP-2598170-A2 | DRUG-LIGAND CONJUGATES, SYNTHESIS THEREOF, AND INTERMEDIATES THERETO | Smartcells, Inc. (US) | 2013-06-05 | — | — | EP | disclosed |
| US-8450298-B2 | Aminoalcohol lipidoids and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2013-05-28 | — | — | US | disclosed |
| WO-2013074986-A1 | INHIBITORS OF C-JUN-N-TERMINAL KINASE (JNK) | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2013-05-23 | — | — | WO | disclosed |
| US-20130131141-A1 | REDUCED SIZE SELF-DELIVERING RNAI COMPOUNDS | PHIO PHARMACEUTICALS CORP. | 2013-05-23 | — | — | US | disclosed |
| US-20130131142-A1 | RNA INTERFERENCE IN OCULAR INDICATIONS | PHIO PHARMACEUTICALS CORP. | 2013-05-23 | — | — | US | disclosed |
| US-20130122535-A1 | METHODS AND COMPOSITIONS FOR LABELING POLYPEPTIDES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2013-05-16 | — | — | US | disclosed |
| WO-2013067460-A1 | METAL COMPLEXES FOR THE COPOLYMERIZATION OF CARBON DIOXIDE AND EPOXIDES | NOVOMER, INC. (US) | 2013-05-10 | — | — | WO | disclosed |
| WO-2013063468-A1 | AMINO ACID DERIVATES FUNCTIONALIZED ON THE N- TERMINAL CAPABLE OF FORMING DRUG INCAPSULATING MICROSPHERES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2013-05-02 | — | — | WO | disclosed |
| EP-2582836-A2 | PRPK-TPRKB MODULATORS AND USES THEREOF | Makoto Life Sciences, Inc. (US) | 2013-04-24 | — | — | EP | disclosed |
| US-8426471-B1 | Methods and compositions for reducing body fat and adipocytes | TOPOKINE THERAPEUTICS, INC. (US) | 2013-04-23 | — | — | US | disclosed |
| US-20130095173-A1 | MULTIVALENT GLYCOPEPTIDE CONSTRUCTS AND USES THEREOF | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2013-04-18 | — | — | US | disclosed |
| US-20130096129-A1 | ACTIVATORS OF CLASS I HISTONE DEACETLYASES (HDACS) AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2013-04-18 | — | — | US | disclosed |
| WO-2013056181-A1 | 3,3 DISUBSTITUTED 19-NOR PREGNANE COMPOUNDS, COMPOSITIONS, AND USES THEREOF | SAGE THERAPEUTICS, INC. (US) | 2013-04-18 | — | — | WO | disclosed |
| EP-2579893-A2 | MULTIVALENT GLYCOPEPTIDE CONSTRUCTS AND USES THEREOF | Sloan Kettering Institute For Cancer Research (US) | 2013-04-17 | — | — | EP | disclosed |
| US-20130079376-A1 | PYRIDYL-2-METHYLAMINO COMPOUNDS, COMPOSITIONS AND USES THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2013-03-28 | — | — | US | disclosed |
| US-20130072485-A1 | SOLUBLE MTOR COMPLEXES AND MODULATORS THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2013-03-21 | — | — | US | disclosed |
| EP-2569019-A2 | COMPOSITIONS, METHODS AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS | Lantheus Medical Imaging, Inc. (US) | 2013-03-20 | — | — | EP | disclosed |
| US-20130066044-A1 | POLYCARBONATE POLYOL COMPOSITIONS AND METHODS | NOVOMER, INC. (US) | 2013-03-14 | — | — | US | disclosed |
| WO-2013036835-A1 | NEUROACTIVE STEROIDS, COMPOSITIONS, AND USES THEREOF | SAGE THERAPEUTICS, INC. (US) | 2013-03-14 | — | — | WO | disclosed |
| WO-2013036869-A2 | COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS | LANTHEUS MEDICAL IMAGING, INC. (US) | 2013-03-14 | — | — | WO | disclosed |
| US-8394818-B2 | Soluble mTOR complexes and modulators thereof | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2013-03-12 | — | — | US | disclosed |
| US-20130059819-A1 | INHIBITORS OF FATTY ACID AMIDE HYDROLASE | INFINITY PHARMACEUTICALS, INC. (US) | 2013-03-07 | — | — | US | disclosed |
| US-20130040952-A1 | INFLUENZA VIRUS INHIBITORS THAT DISRUPT NUCLEOPROTEIN TRIMERIZATION | ACADEMIA SINICA (TW) | 2013-02-14 | — | — | US | disclosed |
| WO-2013022932-A1 | CATALYSTS AND METHODS FOR POLYMER SYNTHESIS | NOVOMER, INC. (US) | 2013-02-14 | — | — | WO | disclosed |
| US-8372884-B2 | Isoprenyl compounds and methods thereof | SIGNUM BIOSCIENCES, INC. | 2013-02-12 | — | — | US | disclosed |
| WO-2013016193-A2 | ACTIVATORS OF CLASS I HISTONE DEACETLYASES (HDACS) AND USES THEREOF | MASSACHUSETTS ISTITUTE OF TECHNOLOGY (US) | 2013-01-31 | — | — | WO | disclosed |
| EP-2550002-A1 | RNA INTERFERENCE IN DERMAL AND FIBROTIC INDICATIONS | Rxi Pharmaceuticals Corporation (US) | 2013-01-30 | — | — | EP | disclosed |
| EP-2550000-A1 | REDUCED SIZE SELF-DELIVERING RNAI COMPOUNDS | Rxi Pharmaceuticals Corporation (US) | 2013-01-30 | — | — | EP | disclosed |
| EP-2550285-A1 | TRIOXACARCINS AND USES THEREOF | President and Fellows of Harvard College (US) | 2013-01-30 | — | — | EP | disclosed |
| EP-2550001-A1 | RNA INTERFERENCE IN OCULAR INDICATIONS | Rxi Pharmaceuticals Corporation (US) | 2013-01-30 | — | — | EP | disclosed |
| EP-2547667-A1 | PROCESS FOR THE PRODUCTION OF 2-AMINO-5-FLUOROTHIAZOLE | Takeda California, Inc. (US) | 2013-01-23 | — | — | EP | disclosed |
| WO-2013006758-A1 | DIPHOSPHATE MIMETICS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2013-01-10 | — | — | WO | disclosed |
| WO-2013006451-A2 | MACROCYCLIC INSULIN-DEGRADING ENZYME (IDE) INHIBITORS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2013-01-10 | — | — | WO | disclosed |
| US-20130011421-A1 | TRITERPENE SAPONINS, METHODS OF SYNTHESIS, AND USES THEREOF | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2013-01-10 | — | — | US | disclosed |
| US-8349814-B2 | Inhibitors of fatty acid amide hydrolase | INFINITY PHARMACEUTICALS, INC. (US) | 2013-01-08 | — | — | US | disclosed |
| US-20130006382-A1 | GASTROINTESTINAL IMPLANT DEVICE | VYSERA BIOMEDICAL LIMITED (IE) | 2013-01-03 | — | — | US | disclosed |
| US-20130004517-A1 | DISC-1 PATHWAY ACTIVATORS IN THE CONTROL OF NEUROGENESIS | THE GENERAL HOSPITAL CORPORATION D/B/A (US) | 2013-01-03 | — | — | US | disclosed |
| WO-2013003315-A2 | METHODS FOR PREPARING ISOQUINOLINES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2013-01-03 | — | — | WO | disclosed |
| US-8343996-B2 | Azaquinolinone derivatives and uses thereof | ASTRAZENECA AB (SE) | 2013-01-01 | — | — | US | disclosed |
| US-20120328514-A1 | N-ALKOXYAMIDE CONJUGATES AS IMAGING AGENTS | LANTHEUS MEDICAL IMAGING, INC. (US) | 2012-12-27 | — | — | US | disclosed |
| US-20120328540-A1 | Cysteinyl compounds, compositions and methods of use | SIGNUM BIOSCIENCES, INC. (US) | 2012-12-27 | — | — | US | disclosed |
| WO-2012174487-A2 | BROMODOMAIN INHIBITORS AND USES THEREOF | CONSTELLATION PHARMACEUTICALS, INC. (US) | 2012-12-20 | — | — | WO | disclosed |
| WO-2012174423-A1 | STABILIZED POLYPEPTIDES AS REGULATORS OF RAB GTPASE FUNCTION | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2012-12-20 | — | — | WO | disclosed |
| US-20120316120-A1 | FLUORINE CONTAINING COMPOUNDS AND METHODS OF USE THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2012-12-13 | — | — | US | disclosed |
| EP-2076133-B1 | SYNTHESIS OF ENONE INTERMEDIATE | HARVARD COLLEGE (US) | 2012-12-12 | — | — | EP | disclosed |
| US-8329675-B2 | Inhibitors of fatty acid amide hydrolase | INFINITY PHARMACEUTICALS, INC. (US) | 2012-12-11 | — | — | US | disclosed |
| US-20120310138-A1 | GASTROINTESTINAL IMPLANT DEVICE AND DELIVERY SYSTEM THEREFOR | VYSERA BIOMEDICAL LIMITED (IE) | 2012-12-06 | — | — | US | disclosed |
| WO-2012167021-A2 | HYPERFORIN ANALOGS, METHODS OF SYNTHESIS, AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2012-12-06 | — | — | WO | disclosed |
| US-20120294804-A1 | PHENYLETHANOLAMINE-BASED NMDA RECEPTOR ANTAGONISTS | COLD SPRING HARBOR LABORATORY (US) | 2012-11-22 | — | — | US | disclosed |
| CN-102781909-A | N-alkoxyamide conjugates as imaging agents | LANTHEUS MEDICAL IMAGING INC | 2012-11-14 | — | — | CN | disclosed |
| WO-2012151512-A2 | BROMODOMAIN INHIBITORS AND USES THEREOF | CONSTELLATION PHARMACEUTICALS, INC. (US) | 2012-11-08 | — | — | WO | disclosed |
| US-20120283842-A1 | ESOPHAGEAL VALVE DEVICE FOR PLACING IN THE CARDIA | VYSERA BIOMEDICAL LIMITED (IE) | 2012-11-08 | — | — | US | disclosed |
| US-20120270800-A1 | BIFUNCTIONAL STAPLED POLYPEPTIDES AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2012-10-25 | — | — | US | disclosed |
| EP-2512386-A1 | A GASTROINTESTINAL IMPLANT DEVICE | Vysera Biomedical Limited (IE) | 2012-10-24 | — | — | EP | disclosed |
| EP-2513200-A1 | A BIOMATERIAL | Vysera Biomedical Limited (IE) | 2012-10-24 | — | — | EP | disclosed |
| EP-2512574-A1 | A UROLOGICAL DEVICE | Vysera Biomedical Limited (IE) | 2012-10-24 | — | — | EP | disclosed |
| US-8293920-B2 | Synthesis of enone intermediate | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2012-10-23 | — | — | US | disclosed |
| US-20120264765-A1 | Cyclohexane-1,3-Diones for Use in the Treatment of Amyotrophic Lateral Sclerosis | CAMBRIA PHARMACEUTICALS, INC. (US) | 2012-10-18 | — | — | US | disclosed |
| WO-2012139074-A2 | MIGRASTATINS AND USES THEREOF | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2012-10-11 | — | — | WO | disclosed |
| EP-2508531-A1 | Stitched polypeptides | President and Fellows of Harvard College (US) | 2012-10-10 | — | — | EP | disclosed |
| US-8283456-B2 | Triterpene saponins, methods of synthesis, and uses thereof | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2012-10-09 | — | — | US | disclosed |
| WO-2012135025-A2 | CONJUGATED LIPOMERS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2012-10-04 | — | — | WO | disclosed |
| US-20120251560-A1 | CONJUGATED LIPOMERS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2012-10-04 | — | — | US | disclosed |
| WO-2012135615-A2 | ENOPEPTINS, USES THEREOF, AND METHODS OF SYNTHESIS THERETO | BROWN UNIVERSITY (US) | 2012-10-04 | — | — | WO | disclosed |
| WO-2012047907-A9 | SYNTHESIS OF C5-SUBSTITUTED TETRACYCLINES, USES THEREOF, AND INTERMEDIATES THERETO | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2012-09-27 | — | — | WO | disclosed |
| US-8263547-B2 | DISC-1 pathway activators in the control of neurogenesis | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2012-09-11 | — | — | US | disclosed |
| WO-2012116410-A1 | METHODS OF TREATING A DISEASE OR CONDITION OF THE CENTRAL NERVOUS SYSTEM | BIONOMICS LIMITED (AU) | 2012-09-07 | — | — | WO | disclosed |
| WO-2012116415-A1 | NOVEL SMALL-MOLECULES AS THERAPEUTICS | BIONOMICS LIMITED (AU) | 2012-09-07 | — | — | WO | disclosed |
| US-8252829-B2 | Aminopyrrolidinone derivatives and uses thereof | LINK MEDICINE CORPORATION (US) | 2012-08-28 | — | — | US | disclosed |
| WO-2012112922-A1 | METHODS FOR SYNTHESIZING MOLYBDOPTERIN PRECURSOR Z DERIVATIVES | ALEXION PHARMACEUTICALS, INC. (US) | 2012-08-23 | — | — | WO | disclosed |
| US-8247520-B2 | Polycarbonate polyol compositions and methods | NOVOMER, INC. (US) | 2012-08-21 | — | — | US | disclosed |
| WO-2012109389-A2 | PALLADIUM NANOWIRES AND METHODS OF PREPARATION | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2012-08-16 | — | — | WO | disclosed |
| WO-2012109538-A2 | SURROGATES OF POST-TRANSLATIONALLY MODIFIED PROTEINS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2012-08-16 | — | — | WO | disclosed |
| EP-2487160-A1 | Synthesis of Enone Intermediate | President and Fellows of Harvard College (US) | 2012-08-15 | — | — | EP | disclosed |
| US-8232402-B2 | Quinolinone farnesyl transferase inhibitors for the treatment of synucleinopathies and other indications | LINK MEDICINE CORPORATION (US) | 2012-07-31 | — | — | US | disclosed |
| US-20120190659-A1 | ANGIOGENESIS INHIBITORS | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2012-07-26 | — | — | US | disclosed |
| WO-2012099942-A2 | METHODS AND COMPOSITIONS FOR TREATING METABOLIC SYNDROME | TERAKINE THERAPEUTICS, INC. (US) | 2012-07-26 | — | — | WO | disclosed |
| EP-2479169-A1 | Synthesis of Enone Intermediate | President and Fellows of Harvard College (US) | 2012-07-25 | — | — | EP | disclosed |
| EP-2476756-A1 | Amine-containing lipids and uses thereof | Massachusetts Institute of Technology (US) | 2012-07-18 | — | — | EP | disclosed |
| US-20120178940-A1 | Functionalized Polymers | QUIAPEG AB (SE) | 2012-07-12 | — | — | US | disclosed |
| CN-102548986-A | Aminopyrrolidinone derivatives and uses thereof | LINK MEDICINE CORP | 2012-07-04 | — | — | CN | disclosed |
| WO-2012084831-A1 | PURIFICATION OF PRECURSOR COMPOUND BY CRYSTALLISATION | GE HEALTHCARE LIMITED (GB) | 2012-06-28 | — | — | WO | disclosed |
| US-20120158026-A1 | GASTROINTESTINAL IMPLANT DEVICE | VYSERA BIOMEDICAL LIMITED (IE) | 2012-06-21 | — | — | US | disclosed |
| US-20120157428-A1 | BROMODOMAIN INHIBITORS AND USES THEREOF | CONSTELLATION PHARMACEUTICALS, INC. (US) | 2012-06-21 | — | — | US | disclosed |
| WO-2012080836-A2 | FUNCTIONALIZED POLYMERS | KWIATKOWSKI MAREK (SE) | 2012-06-21 | — | — | WO | disclosed |
| WO-2012075393-A2 | ACTIVATORS OF PROTEASOMAL DEGRADATION AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2012-06-07 | — | — | WO | disclosed |
| WO-2012075383-A2 | BROMODOMAIN INHIBITORS AND USES THEREOF | CONSTELLATION PHARMACEUTICALS, INC. (US) | 2012-06-07 | — | — | WO | disclosed |
| WO-2012075456-A1 | BROMODOMAIN INHIBITORS AND USES THEREOF | CONSTELLATION PHARMACEUTICALS (US) | 2012-06-07 | — | — | WO | disclosed |
| WO-2012072567-A1 | PREPARATION OF PET PRECURSOR | GE HEALTHCARE LIMITED (GB) | 2012-06-07 | — | — | WO | disclosed |
| WO-2012075277-A2 | SYNTHETIC METHODS | NOVOMER, INC. (US) | 2012-06-07 | — | — | WO | disclosed |
| US-20120136073-A1 | Amine-Containing Transfection Reagents and methods for making and using same | Life Technologies Corporation (US) | 2012-05-31 | — | — | US | disclosed |
| WO-2012068176-A1 | AMINE-CONTAINING TRANSFECTION REAGENTS AND METHODS FOR MAKING AND USING SAME | Life Technologies Corporation (US) | 2012-05-24 | — | — | WO | disclosed |
| EP-2453908-A2 | BIFUNCTIONAL STAPLED POLYPEPTIDES AND USES THEREOF | President and Fellows of Harvard College (US) | 2012-05-23 | — | — | EP | disclosed |
| EP-2451776-A2 | N-ALKOXYAMIDE CONJUGATES AS IMAGING AGENTS | Lantheus Medical Imaging, Inc. (US) | 2012-05-16 | — | — | EP | disclosed |
| US-20120115818-A1 | SYNTHESIS OF TETRACYCLINES AND INTERMEDIATES THERETO | PRESIDENT AND FELOWS OF HARVARD COLLEGE (US) | 2012-05-10 | — | — | US | disclosed |
| US-20120108605-A1 | O-GLCNAC TRANSFERASE INHIBITORS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2012-05-03 | — | — | US | disclosed |
| US-20120108889-A1 | UROLOGICAL DEVICE | VYSERA BIOMEDICAL LIMITED (IE) | 2012-05-03 | — | — | US | disclosed |
| US-20120094939-A1 | ANTI-VIRAL COMPOUNDS, COMPOSITIONS AND METHODS | TRUSTEES OF BOSTON UNIVERSITY | 2012-04-19 | — | — | US | disclosed |
| US-20120088916-A1 | OCTAHYDRO BIQUINOLINE COMPOUND | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2012-04-12 | — | — | US | disclosed |
| WO-2012047907-A1 | SYNTHESIS OF C5-SUBSTITUTED TETRACYCLINES, USES THEREOF, AND INTERMEDIATES THERETO | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2012-04-12 | — | — | WO | disclosed |
| EP-2438059-A1 | AMINOPYRROLIDINONE DERIVATIVES AND USES THEREOF | Link Medicine Corporation (US) | 2012-04-11 | — | — | EP | disclosed |
| EP-2438046-A2 | O-GLCNAC TRANSFERASE INHIBITORS AND USES THEREOF | President and Fellows of Harvard College (US) | 2012-04-11 | — | — | EP | disclosed |
| WO-2012040459-A2 | BETA-CATENIN TARGETING PEPTIDES AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2012-03-29 | — | — | WO | disclosed |
| EP-2432771-A1 | ISOXAZOLINES AS INHIBITORS OF FATTY ACID AMIDE HYDROLASE | Infinity Pharmaceuticals, Inc. (US) | 2012-03-28 | — | — | EP | disclosed |
| WO-2012037282-A2 | CATALYSTS AND METHODS FOR POLYMER SYNTHESIS | NOVOMER, INC. (US) | 2012-03-22 | — | — | WO | disclosed |
| EP-2427438-A2 | PYRIMIDINE-2,4,6-TRIONES FOR USE IN THE TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS | Cambria Pharmaceuticals, Inc. (US) | 2012-03-14 | — | — | EP | disclosed |
| US-20120059486-A1 | ESOPHAGEAL VALVE | VYSERA BIOMEDICAL LIMITED (IE) | 2012-03-08 | — | — | US | disclosed |
| EP-2424834-A2 | SYNTHESIS OF TETRACYCLINES AND INTERMEDIATES THERETO | President and Fellows of Harvard College (US) | 2012-03-07 | — | — | EP | disclosed |
| CN-102369202-A | Azaquinolinone derivatives and uses thereof | LINK MEDICINE CORP | 2012-03-07 | — | — | CN | disclosed |
| US-8129388-B2 | Therapeutic agents useful for treating pain | Purde Pharma L.P. (US) | 2012-03-06 | — | — | US | disclosed |
| WO-2012027555-A2 | GLYCATED CD59 PEPTIDES, THEIR PREPARATION, AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2012-03-01 | — | — | WO | disclosed |
| WO-2012027675-A2 | POLY(BETA-AMINO ALCOHOLS), THEIR PREPARATION, AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2012-03-01 | — | — | WO | disclosed |
| EP-2421882-A2 | ANGIOGENESIS INHIBITORS | President and Fellows of Harvard College (US) | 2012-02-29 | — | — | EP | disclosed |
| CN-102365025-A | Conjugate-based systems for controlled drug delivery | SMARTCELLS INC | 2012-02-29 | — | — | CN | disclosed |
| US-20120046309-A1 | PYRIMIDINE-2,4,6-TRIONES FOR USE IN THE TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS | NORTHWESTERN UNIVERSITY (US) | 2012-02-23 | — | — | US | disclosed |
| US-20120046282-A1 | METHODS AND COMPOUNDS FOR ANTIMICROBIAL INTERVENTION | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2012-02-23 | — | — | US | disclosed |
| WO-2012024604-A2 | HIGH-VALENT PALLADIUM FLUORIDE COMPLEXES AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2012-02-23 | — | — | WO | disclosed |
| US-20120046223-A1 | EXOGENOUSLY TRIGGERED CONTROLLED RELEASE MATERIALS AND USES THEREOF | SMARTCELLS, INC. | 2012-02-23 | — | — | US | disclosed |
| US-20120029199-A1 | SYNTHESIS OF ENONE INTERMEDIATE | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2012-02-02 | — | — | US | disclosed |
| WO-2012016186-A1 | MACROCYCLIC KINASE INHIBITORS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2012-02-02 | — | — | WO | disclosed |
| WO-2012015681-A2 | DRUG-LIGAND CONJUGATES, SYNTHESIS THEREOF, AND INTERMEDIATES THERETO | SMARTCELLS, INC. (US) | 2012-02-02 | — | — | WO | disclosed |
| WO-2012015691-A2 | RECOMBINANT LECTINS, BINDING-SITE MODIFIED LECTINS AND USES THEREOF | SMARTCELLS, INC. (US) | 2012-02-02 | — | — | WO | disclosed |
| EP-2408808-A1 | TERMINALLY-FUNCTIONALIZED CONJUGATES AND USES THEREOF | Smartcells, Inc. (US) | 2012-01-25 | — | — | EP | disclosed |
| US-20120014908-A1 | TERMINALLY-FUNCTIONALIZED CONJUGATES AND USES THEREOF | SMARTCELLS, INC. | 2012-01-19 | — | — | US | disclosed |
| WO-2012006104-A2 | COMPOUNDS AND METHODS FOR TREATING TUBERCULOSIS INFECTION | Academia Sinica, Taiwan (TW) | 2012-01-12 | — | — | WO | disclosed |
| US-20120009222-A1 | MODULATION OF THE IMMUNE RESPONSE | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2012-01-12 | — | — | US | disclosed |
| EP-2404607-A1 | Boronic acids and esters as inhibitors of fatty acid amide hydrolase | Infinity Pharmaceuticals, Inc. (US) | 2012-01-11 | — | — | EP | disclosed |
| US-20110319277-A1 | PRPK-TPRKB MODULATORS AND USES THEREOF | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2011-12-29 | — | — | US | disclosed |
| US-20110321183-A1 | METHODS FOR LIGATION AND USES THEREOF | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2011-12-29 | — | — | US | disclosed |
| WO-2011163483-A2 | POLYMERS FOR BIOMATERIALS AND THERAPEUTICS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2011-12-29 | — | — | WO | disclosed |
| EP-2399585-A1 | Boronic acids and esters as inhibitors of fatty acid amide hydrolase | Infinity Pharmaceuticals, Inc. (US) | 2011-12-28 | — | — | EP | disclosed |
| EP-2399584-A1 | Boronic acids and esters as inhibitors of fatty acid amide hydrolase | Infinity Pharmaceuticals, Inc. (US) | 2011-12-28 | — | — | EP | disclosed |
| WO-2011160042-A2 | PRPK-TPRKB MODULATORS AND USES THEREOF | MAKOTO LIFE SCIENCES, INC. (US) | 2011-12-22 | — | — | WO | disclosed |
| WO-2011156774-A2 | MULTIVALENT GLYCOPEPTIDE CONSTRUCTS AND USES THEREOF | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2011-12-15 | — | — | WO | disclosed |
| US-20110300177-A1 | TRITERPENE SAPONINS, METHODS OF SYNTHESIS, AND USES THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-12-08 | — | — | US | disclosed |
| US-20110301083-A1 | CONJUGATE BASED SYSTEMS FOR CONTROLLED DRUG DELIVERY | SMARTCELLS, INC. | 2011-12-08 | — | — | US | disclosed |
| EP-2391216-A1 | EXOGENOUSLY TRIGGERED CONTROLLED RELEASE MATERIALS AND USES THEREOF | Smartcells, Inc. (US) | 2011-12-07 | — | — | EP | disclosed |
| EP-2391215-A1 | BINDING-SITE MODIFIED LECTINS AND USES THEREOF | Smartcells, Inc. (US) | 2011-12-07 | — | — | EP | disclosed |
| EP-2391646-A1 | CRYSTALLINE INSULIN-CONJUGATES | Smartcells, Inc. (US) | 2011-12-07 | — | — | EP | disclosed |
| US-20110294794-A1 | TREATMENT OF PROTEINOPATHIES USING A FARNESYL TRANSFERASE INHIBITOR | LINK MEDICINE CORPORATION (US) | 2011-12-01 | — | — | US | disclosed |
| US-20110293703-A1 | AMINOALCOHOL LIPIDOIDS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2011-12-01 | — | — | US | disclosed |
| EP-2389357-A1 | ANTI-INFLAMMATORY COMPLEXES | Signum Biosciences, Inc. (US) | 2011-11-30 | — | — | EP | disclosed |
| US-20110288100-A1 | THERAPEUTIC AGENTS USEFUL FOR TREATING PAIN | PURDUE PHARMA L.P. (US) | 2011-11-24 | — | — | US | disclosed |
| US-20110288091-A1 | SOLUBLE MTOR COMPLEXES AND MODULATORS THEREOF | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2011-11-24 | — | — | US | disclosed |
| US-20110281792-A1 | BINDING-SITE MODIFIED LECTINS AND USES THEREOF | SMARTCELLS, INC. | 2011-11-17 | — | — | US | disclosed |
| US-20110281939-A1 | POLYNUCLEOTIDE APTAMER-BASED CROSS-LINKED MATERIALS AND USES THEREOF | SMARTCELLS, INC. | 2011-11-17 | — | — | US | disclosed |
| US-20110281876-A1 | THERAPEUTIC AGENTS USEFUL FOR TREATING PAIN | PURDUE PHARMA L.P. (US) | 2011-11-17 | — | — | US | disclosed |
| US-20110281791-A1 | CRYSTALLINE INSULIN-CONJUGATES | SMARTCELLS, INC. | 2011-11-17 | — | — | US | disclosed |
| WO-2011143360-A2 | COMPOSITIONS, METHODS AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS | LANTHEUS MEDICAL IMAGING, INC. (US) | 2011-11-17 | — | — | WO | disclosed |
| US-20110275560-A1 | SYNTHETIC CONJUGATES AND USES THEREOF | SMARTCELLS, INC. | 2011-11-10 | — | — | US | disclosed |
| US-20110269972-A1 | NOVEL TRICYCLIC CHIRAL COMPOUNDS AND THEIR USE IN ASYMMETRIC CATALYSIS | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2011-11-03 | — | — | US | disclosed |
| WO-2011137320-A2 | SMALL MOLECULE INHIBITORS OF USP1 DEUBIQUITINATING ENZYME ACTIVITY | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2011-11-03 | — | — | WO | disclosed |
| US-20110263569-A1 | RYANODINE CHANNEL BINDERS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2011-10-27 | — | — | US | disclosed |
| US-20110263532-A1 | HALOFUGINONE ANALOGS FOR INHIBITION OF TRNA SYNTHETASES AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2011-10-27 | — | — | US | disclosed |
| US-20110263563-A1 | Ansamycin Hydroquinone Compositions | Infinity Disdcovery, Inc. (US) | 2011-10-27 | — | — | US | disclosed |
| US-8038936-B2 | Cooking device with deodorization | LG ELECTRONICS INC. (KR) | 2011-10-18 | — | — | US | disclosed |
| EP-2370436-A1 | AZAQUINOLINONE DERIVATIVES AND USES THEREOF | Link Medicine Corporation (US) | 2011-10-05 | — | — | EP | disclosed |
| US-8029557-B2 | Esophageal valve | VYSERA BIOMEDICAL LIMITED (IE) | 2011-10-04 | — | — | US | disclosed |
| WO-2011119871-A1 | RNA INTERFERENCE IN OCULAR INDICATIONS | RXI PHRMACEUTICALS CORPORATION (US) | 2011-09-29 | — | — | WO | disclosed |
| WO-2011119887-A1 | RNA INTERFERENCE IN DERMAL AND FIBROTIC INDICATIONS | RXI PHARMACEUTICALS CORPORATION (US) | 2011-09-29 | — | — | WO | disclosed |
| US-20110237907-A1 | TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS | CAMBRIA PHARMACEUTICALS, INC. (US) | 2011-09-29 | — | — | US | disclosed |
| WO-2011119852-A1 | REDUCED SIZE SELF-DELIVERING RNAI COMPOUNDS | RXI PHARMACEUTICALS CORPORATION (US) | 2011-09-29 | — | — | WO | disclosed |
| WO-2011119549-A1 | TRIOXACARCINS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2011-09-29 | — | — | WO | disclosed |
| EP-2367798-A2 | TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS | Cambria Pharmaceuticals, Inc. (US) | 2011-09-28 | — | — | EP | disclosed |
| US-20110230440-A1 | INHIBITORS OF FATTY ACID AMIDE HYDROLASE | ADAMS JULIAN | 2011-09-22 | — | — | US | disclosed |
| US-20110230580-A1 | POLYCARBONATE POLYOL COMPOSITIONS AND METHODS | Novomer, Inc (US) | 2011-09-22 | — | — | US | disclosed |
| US-20110230551-A1 | WITHAFERIN A ANALOGS AND USES THEREOF | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 2011-09-22 | — | — | US | disclosed |
| WO-2011115758-A1 | PROCESS FOR THE PRODUCTION OF 2-AMINO-5-FLUOROTHIAZOLE | TAKEDA SAN DIEGO, INC. (US) | 2011-09-22 | — | — | WO | disclosed |
| US-20110229510-A1 | GLYCOPEPTIDE CONSTRUCTS AND USES THEREOF | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2011-09-22 | — | — | US | disclosed |
| EP-2365962-A2 | AMINOALCOHOL LIPIDOIDS AND USES THEREOF | Massachusetts Institute of Technology (US) | 2011-09-21 | — | — | EP | disclosed |
| US-20110224171-A1 | INHIBITORS OF FATTY ACID AMIDE HYDROLASE | INFINITY DISCOVERY, INC. | 2011-09-15 | — | — | US | disclosed |
| US-20110224321-A1 | Biomaterial | VYSERA BIOMEDICAL LIMITED (IE) | 2011-09-15 | — | — | US | disclosed |
| EP-2073816-B1 | BORONIC ACIDS AND ESTERS AS INHIBITORS OF FATTY ACID AMIDE HYDROLASE | INFINITY PHARMACEUTICALS INC (US) | 2011-09-14 | — | — | EP | disclosed |
| EP-2362866-A1 | ISOPRENYL COMPOUNDS AND METHODS THEREOF | Signum Biosciences, Inc. (US) | 2011-09-07 | — | — | EP | disclosed |
| US-20110212936-A1 | HIGH-VALENT PALLADIUM FLUORIDE COMPLEXES AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2011-09-01 | — | — | US | disclosed |
| EP-2356139-A2 | LIGATION OF STAPLED POLYPEPTIDES | President and Fellows of Harvard College (US) | 2011-08-17 | — | — | EP | disclosed |
| US-7998965-B2 | Glutamate aggrecanase inhibitors | WYETH LLC (US) | 2011-08-16 | — | — | US | disclosed |
| US-7994177-B2 | Therapeutic agents useful for treating pain | PURDUE PHARMA L.P. (US) | 2011-08-09 | — | — | US | disclosed |
| US-20110190905-A1 | GASTROINTESTINAL IMPLANT | VYSERA BIOMEDICAL LIMITED (IE) | 2011-08-04 | — | — | US | disclosed |
| US-20110190323-A1 | CORTISTATIN ANALOGUES AND SYNTHESES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2011-08-04 | — | — | US | disclosed |
| EP-2350053-A2 | SOLUBLE MTOR COMPLEXES AND MODULATORS THEREOF | Whitehead Institute For Biomedical Research (US) | 2011-08-03 | — | — | EP | disclosed |
| EP-2348845-A1 | ANSAMYCIN HYDROQUINONE COMPOSITIONS | Infinity Pharmaceuticals, Inc. (US) | 2011-08-03 | — | — | EP | disclosed |
| US-7985594-B2 | Biradical polarizing agents for dynamic nuclear polarization | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2011-07-26 | — | — | US | disclosed |
| US-20110172233-A1 | SONIC HEDGEHOG MODULATORS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2011-07-14 | — | — | US | disclosed |
| US-20110166170-A1 | SYNTHESIS OF AVRAINVILLAMIDE, STEPHACIDIN B, AND ANALOGUES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2011-07-07 | — | — | US | disclosed |
| US-20110160836-A1 | VALVE DEVICE | VYSERA BIOMEDICAL LIMITED (IE) | 2011-06-30 | — | — | US | disclosed |
| US-20110160706-A1 | UROLOGICAL DEVICE | VYSERA BIOMEDICAL LIMITED (IE) | 2011-06-30 | — | — | US | disclosed |
| EP-2337809-A1 | POLYCARBONATE POLYOL COMPOSITIONS AND METHODS | Novomer, Inc. (US) | 2011-06-29 | — | — | EP | disclosed |
| EP-2337522-A1 | ESOPHAGEAL VALVE | Vysera Biomedical Limited (IE) | 2011-06-29 | — | — | EP | disclosed |
| US-20110152497-A1 | CATALYSTS AND METHODS FOR POLYMER SYNTHESIS | NOVOMER, INC. (US) | 2011-06-23 | — | — | US | disclosed |
| WO-2011073970-A1 | A GASTROINTESTINAL IMPLANT DEVICE | VYSERA BIOMEDICAL LIMITED (IE) | 2011-06-23 | — | — | WO | disclosed |
| WO-2011073969-A1 | A UROLOGICAL DEVICE | VYSERA BIOMEDICAL LIMITED (IE) | 2011-06-23 | — | — | WO | disclosed |
| WO-2011073968-A1 | A DRUG DELIVERY SYSTEM | VYSERA BIOMEDICAL LIMITED (IE) | 2011-06-23 | — | — | WO | disclosed |
| US-20110153027-A1 | Drug Delivery System | VYSERA BIOMEDICAL LIMITED (IE) | 2011-06-23 | — | — | US | disclosed |
| US-20110152395-A1 | Biomaterial | VYSERA BIOMEDICAL LIMITED (IE) | 2011-06-23 | — | — | US | disclosed |
| WO-2011073967-A1 | A BIOMATERIAL | VYSERA BIOMEDICAL LIMITED (IE) | 2011-06-23 | — | — | WO | disclosed |
| EP-2334686-A2 | CORTISTATIN ANALOGUES AND SYNTHESES THEROF | President and Fellows of Harvard College (US) | 2011-06-22 | — | — | EP | disclosed |
| US-7964606-B2 | Therapeutic agents useful for treating pain | PURDUE PHARMA L.P. (US) | 2011-06-21 | — | — | US | disclosed |
| US-20110144306-A1 | LIGATION OF STAPLED POLYPEPTIDES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2011-06-16 | — | — | US | disclosed |
| EP-2331525-A2 | HALOFUGINONE ANALOGS FOR INHIBITION OF TRNA SYNTHETASES AND USES THEREOF | President and Fellows of Harvard College (US) | 2011-06-15 | — | — | EP | disclosed |
| EP-2331017-A1 | ESOPHAGEAL VALVE | VYS RA Biomedical Limited (IE) | 2011-06-15 | — | — | EP | disclosed |
| EP-2331018-A1 | ESOPHAGEAL VALVE | Vysera Biomedical Limited (IE) | 2011-06-15 | — | — | EP | disclosed |
| US-7960559-B2 | Synthesis of enone intermediate | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2011-06-14 | — | — | US | disclosed |
| US-20110136759-A1 | MOENOMYCIN ANALOGS, METHODS OF SYNTHESIS, AND USES THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-06-09 | — | — | US | disclosed |
| US-7947663-B2 | Inhibitors of fatty acid amide hydrolase | INFINITY PHARMACEUTICALS, INC. (US) | 2011-05-24 | — | — | US | disclosed |
| WO-2011059821-A2 | CYCLOHEXANE-1,3-DIONES FOR USE IN THE TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS | CAMBRIA PHARMACEUTICALS, INC. (US) | 2011-05-19 | — | — | WO | disclosed |
| US-20110118265-A1 | USE OF ANTI-BACTERIAL AGENTS FOR THE TREATMENT OF EPITHELIAL-RELATED CONDITIONS | SIGNUM DERMALOGIX, INC. | 2011-05-19 | — | — | US | disclosed |
| EP-2321364-A2 | CATALYSTS AND METHODS FOR POLYMER SYNTHESIS | Novomer, Inc. (US) | 2011-05-18 | — | — | EP | disclosed |
| EP-2317994-A2 | ACTIVATION OF HISTONE DEACETYLASE 1 (HDAC1) PROTECTS AGAINST DNA DAMAGE AND INCREASES NEURONAL SURVIVAL | Massachusetts Institute of Technology (US) | 2011-05-11 | — | — | EP | disclosed |
| US-20110105515-A1 | TARGETING THE ONCOPROTEIN NUCLEOPHOSMIN | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2011-05-05 | — | — | US | disclosed |
| EP-2315771-A2 | GLYCOPEPTIDE CONSTRUCTS AND USES THEREOF | Sloan Kettering Institute For Cancer Research (US) | 2011-05-04 | — | — | EP | disclosed |
| US-7932343-B2 | Biomaterial | VYSERA BIOMEDICAL LIMITED (IE) | 2011-04-26 | — | — | US | disclosed |
| US-20110082152-A1 | THERAPEUTIC AGENTS USEFUL FOR TREATING PAIN | PURDUE PHARMA L.P. (US) | 2011-04-07 | — | — | US | disclosed |
| EP-2303897-A1 | HIGH-VALENT PALLADIUM FLUORIDE COMPLEXES AND USES THEREOF | President and Fellows of Harvard College (US) | 2011-04-06 | — | — | EP | disclosed |
| EP-2303888-A2 | METHODS AND COMPOUNDS FOR ANTIMICROBIAL INTERVENTION | President and Fellows of Harvard College (US) | 2011-04-06 | — | — | EP | disclosed |
| EP-2296581-A1 | A BIOMATERIAL | Vysera Biomedical Limited (IE) | 2011-03-23 | — | — | EP | disclosed |
| US-7910623-B2 | Synthesis of scabronines and analogues thereof | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2011-03-22 | — | — | US | disclosed |
| US-7902196-B2 | Synthesis of avrainvillamide, strephacidin B, and analogues thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2011-03-08 | — | — | US | disclosed |
| US-20110054175-A1 | SYSTEM FOR FLUORINATING ORGANIC COMPOUNDS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2011-03-03 | — | — | US | disclosed |
| US-20110052673-A1 | THERAPEUTIC COMPOSITIONS | SHIRE HUMAN GENETIC THERAPIES, INC. | 2011-03-03 | — | — | US | disclosed |
| EP-2282735-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR MAKING THE SAME | Signum Biosciences, Inc. (US) | 2011-02-16 | — | — | EP | disclosed |
| US-20110034437-A1 | ISOXAZOLINES AS INHIBITORS OF FATTY ACID AMIDE HYDROLASE | INFINITY PHARMACEUTICALS, INC. (US) | 2011-02-10 | — | — | US | disclosed |
| EP-2280987-A2 | TRITERPENE SAPONINS, METHODS OF SYNTHESIS, AND USES THEREOF | Sloan Kettering Institute For Cancer Research (US) | 2011-02-09 | — | — | EP | disclosed |
| US-20110028482-A1 | ISOXAZOLINES AS INHIBITORS OF FATTY ACID AMIDE HYDROLASE | INFINITY PHARMACEUTICALS, INC. (US) | 2011-02-03 | — | — | US | disclosed |
| US-20110028478-A1 | ISOXAZOLINES AS INHIBITORS OF FATTY ACID AMIDE HYDROLASE | INFINITY PHARMACEUTICALS, INC. (US) | 2011-02-03 | — | — | US | disclosed |
| WO-2009042972-A9 | FLUORINATED LIPIDS AND METHODS OF USE | TUFTS UNIVERSITY (US) | 2011-02-03 | — | — | WO | disclosed |
| US-20110021590-A1 | AMINOPYRROLIDINONE DERIVATIVES AND USES THEREOF | LINK MEDICINE CORPORATION (US) | 2011-01-27 | — | — | US | disclosed |
| WO-2011008260-A2 | BIFUNCTIONAL STAPLED POLYPEPTIDES AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2011-01-20 | — | — | WO | disclosed |
| US-20110015137-A1 | RECA INHIBITORS AND THEIR USES AS MICROBIAL INHIBITORS OR POTENTIATORS OF ANTIBIOTIC ACTIVITY | TRUSTEES OF BOSTON UNIVERSITY (US) | 2011-01-20 | — | — | US | disclosed |
| EP-2017276-B1 | Phenyl-carboxamide compounds useful for treating pain | EURO CELTIQUE SA (LU) | 2011-01-19 | — | — | EP | disclosed |
| US-20110008277-A1 | POLYOL-BASED POLYMERS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2011-01-13 | — | — | US | disclosed |
| US-20110009418-A1 | THERAPEUTIC AGENTS USEFUL FOR TREATING PAIN | PURDUE PHARMA L.P. (US) | 2011-01-13 | — | — | US | disclosed |
| WO-2011006088-A2 | FLUORINE CONTAINING COMPOUNDS AND METHODS OF USE THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2011-01-13 | — | — | WO | disclosed |
| US-20110009639-A1 | SYNTHESIS OF ENONE INTERMEDIATE | MYERS ANDREW G | 2011-01-13 | — | — | US | disclosed |
| US-20110009485-A9 | SYNTHESIS OF SCABRONINES AND ANALOGUES THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-01-13 | — | — | US | disclosed |
| US-20110009371-A1 | SYNTHESIS OF TETRACYCLINES AND ANALOGUES THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-01-13 | — | — | US | disclosed |
| WO-2011005322-A2 | N-ALKOXYAMIDE CONJUGATES AS IMAGING AGENTS | LANTHEUS MEDICAL IMAGING, INC. (US) | 2011-01-13 | — | — | WO | disclosed |
| US-20110009641-A1 | Amine-containing lipids and uses thereof | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-01-13 | — | — | US | disclosed |
| US-20100331234-A1 | AMINOALCOHOL LIPIDOIDS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2010-12-30 | — | — | US | disclosed |
| US-7855210-B2 | Therapeutic agents useful for treating pain | PURDUE PHARMA, L.P. (US) | 2010-12-21 | — | — | US | disclosed |
| US-20100317670-A1 | THERAPEUTIC AGENTS USEFUL FOR TREATING PAIN | PURDUE PHARMA L.P. (US) | 2010-12-16 | — | — | US | disclosed |
| US-7851658-B2 | Palladium-catalyzed carbon-carbon bond forming reactions | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2010-12-14 | — | — | US | disclosed |
| WO-2010141932-A1 | AMINOPYRROLIDINONE DERIVATIVES AND USES THEREOF | LINK MEDICINE CORPORATION (US) | 2010-12-09 | — | — | WO | disclosed |
| WO-2010141074-A2 | O-GLCNAC TRANSFERASE INHIBITORS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2010-12-09 | — | — | WO | disclosed |
| WO-2010135360-A1 | ISOXAZOLINES AS INHIBITORS OF FATTY ACID AMIDE HYDROLASE | INFINITY PHARMACEUTICALS, INC. (US) | 2010-11-25 | — | — | WO | disclosed |
| US-20100292292-A1 | Treatment of Neurodegenerative Diseases Using Indatraline Analogs | LINK MEDICINE CORPORATION (US) | 2010-11-18 | — | — | US | disclosed |
| WO-2010129665-A2 | PYRIMIDINE-2,4,6-TRIONES FOR USE IN THE TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS | CAMBRIA PHARMACEUTICALS, INC. (US) | 2010-11-11 | — | — | WO | disclosed |
| US-20100286250-A1 | FLUORINATED LIPIDS AND METHODS OF USE | TUFTS UNIVERSITY (US) | 2010-11-11 | — | — | US | disclosed |
| WO-2010126607-A2 | SYNTHESIS OF TETRACYCLINES AND INTERMEDIATES THERETO | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2010-11-04 | — | — | WO | disclosed |
| EP-2244694-A2 | THERAPEUTIC COMPOSITIONS COMPRISING AN AMINE-CONTAINING LIPID AND A PROTEIN | Shire Human Genetic Therapies, Inc. (US) | 2010-11-03 | — | — | EP | disclosed |
| WO-2010123545-A2 | ANGIOGENESIS INHIBITORS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2010-10-28 | — | — | WO | disclosed |
| US-7807842-B2 | Synthesis of tetracyclines and analogues thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2010-10-05 | — | — | US | disclosed |
| US-20100247461-A1 | ANTI-INFLAMMATORY COMPLEXES | SIGNUM BIOSCIENCES, INC. (US) | 2010-09-30 | — | — | US | disclosed |
| WO-2010107519-A1 | TERMINALLY-FUNCTIONALIZED CONJUGATES AND USES THEREOF | SMARTCELLS, INC. (US) | 2010-09-23 | — | — | WO | disclosed |
| US-7799807-B2 | Therapeutic agents useful for treating pain | PURDUE PHARMA L.P. (US) | 2010-09-21 | — | — | US | disclosed |
| WO-2010057006-A9 | AZAQUINOLINONE DERIVATIVES AND USES THEREOF | LINK MEDICINE CORPORATION (US) | 2010-09-16 | — | — | WO | disclosed |
| WO-2010057028-A9 | TREATMENT OF PROTEINOPATHIES USING A FARNESYL TRANSFERASE INHIBITOR | LINK MEDICINE CORPORATION (US) | 2010-09-02 | — | — | WO | disclosed |
| WO-2010090845-A1 | ANTI-INFLAMMATORY COMPLEXES | SIGNUM BIOSCIENCES, INC. (US) | 2010-08-12 | — | — | WO | disclosed |
| US-7772254-B2 | Therapeutic agents useful for treating pain | PURDUE PHARMA L.P. (US) | 2010-08-10 | — | — | US | disclosed |
| WO-2010088286-A1 | SYNTHETIC CONJUGATES AND USES THEREOF | SMARTCELLS, INC. (US) | 2010-08-05 | — | — | WO | disclosed |
| WO-2010088276-A2 | POLYNUCLEOTIDE APTAMER-BASED CROSS -LINKED MATERIALS AND USES THEREOF | SMARTCELLS, INC. (US) | 2010-08-05 | — | — | WO | disclosed |
| WO-2010088261-A1 | BINDING-SITE MODIFIED LECTINS AND USES THEREOF | SMARTCELLS, INC. (US) | 2010-08-05 | — | — | WO | disclosed |
| WO-2010087994-A2 | METHODS FOR LIGATION AND USES THEREOF | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2010-08-05 | — | — | WO | disclosed |
| WO-2010088300-A1 | CRYSTALLINE INSULIN-CONJUGATES | SMARTCELLS, INC. (US) | 2010-08-05 | — | — | WO | disclosed |
| WO-2010088268-A1 | EXOGENOUSLY TRIGGERED CONTROLLED RELEASE MATERIALS AND USES THEREOF | SMARTCELLS, INC. (US) | 2010-08-05 | — | — | WO | disclosed |
| WO-2010088294-A1 | CONJUGATE BASED SYSTEMS FOR CONTROLLED DRUG DELIVERY | SMARTCELLS, INC. (US) | 2010-08-05 | — | — | WO | disclosed |
| US-20100190991-A1 | SYNTHESIS OF THIOHYDANTOINS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2010-07-29 | — | — | US | disclosed |
| US-7763735-B2 | modular synthesis of tetracycline analogs through a chiral enone intermediate; efficiency | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2010-07-27 | — | — | US | disclosed |
| US-20100184768-A1 | Isoprenyl Compounds and Methods Thereof | SIGNUM BIOSCIENCES, INC. (US) | 2010-07-22 | — | — | US | disclosed |
| US-20100184645-A1 | STITCHED POLYPEPTIDES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2010-07-22 | — | — | US | disclosed |
| EP-2205074-A2 | MOENOMYCIN ANALOGS, METHODS OF SYNTHESIS, AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2010-07-14 | — | — | EP | disclosed |
| US-7754723-B2 | Therapeutic agents useful for treating pain | PURDUE PHARMA, L.P., USA | 2010-07-13 | — | — | US | disclosed |
| US-7737148-B2 | Therapeutic agents useful for treating pain | PURDUE PHARMA, L.P. (US) | 2010-06-15 | — | — | US | disclosed |
| WO-2010062322-A2 | MODULATION OF THE IMMUNE RESPONSE | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2010-06-03 | — | — | WO | disclosed |
| WO-2010062372-A2 | METHODS FOR MODULATING NF-KB USING GIBBERELLINS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2010-06-03 | — | — | WO | disclosed |
| US-20100137998-A1 | ESOPHAGEAL VALVE | VYSERA BIOMEDICAL LIMITED (IE) | 2010-06-03 | — | — | US | disclosed |
| WO-2010059241-A2 | TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS | CAMBRIA PHARMACEUTICALS, INC. (US) | 2010-05-27 | — | — | WO | disclosed |
| US-20100130540-A1 | AZAQUINOLINONE DERIVATIVES AND USES THEREOF | LINK MEDICINE CORPORATION (US) | 2010-05-27 | — | — | US | disclosed |
| US-20100130451-A1 | SYNTHESIS OF TETRACYCLINES AND ANALOGUES THEREOF | PRESIDENTS AND FELLOWS OF HARVARD COLLEGE (US) | 2010-05-27 | — | — | US | disclosed |
| WO-2010057006-A1 | AZAQUINOLINONE DERIVATIVES AND USES THEREOF | LINK MEDICINE CORPORATION (US) | 2010-05-20 | — | — | WO | disclosed |
| WO-2010056778-A1 | ISOPRENYL COMPOUNDS AND METHODS THEREOF | SIGNUM BIOSCIENCES, INC. (US) | 2010-05-20 | — | — | WO | disclosed |
| WO-2010057028-A2 | TREATMENT OF PROTEINOPATHIES USING A FARNESYL TRANSFERASE INHIBITOR | LINK MEDICINE CORPORATION (US) | 2010-05-20 | — | — | WO | disclosed |
| WO-2010053572-A2 | AMINOALCOHOL LIPIDOIDS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2010-05-14 | — | — | WO | disclosed |
| US-20100120934-A1 | BIOMATERIAL | VYSERA BIOMEDICAL LIMITED (IE) | 2010-05-13 | — | — | US | disclosed |
| US-20100121462-A1 | VALVE | VYSERA BIOMEDICAL LIMITED (IE) | 2010-05-13 | — | — | US | disclosed |
| US-20100121461-A1 | VALVE | VYSERA BIOMEDICAL LIMITED (IE) | 2010-05-13 | — | — | US | disclosed |
| EP-1810970-B1 | Therapeutic piperazine compounds | EURO CELTIQUE SA (LU) | 2010-05-12 | — | — | EP | disclosed |
| WO-2010044885-A2 | SOLUBLE MTOR COMPLEXES AND MODULATORS THEREOF | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2010-04-22 | — | — | WO | disclosed |
| WO-2010045442-A1 | ANSAMYCIN HYDROQUINONE COMPOSITIONS | INFINITY DISCOVERY, INC. (US) | 2010-04-22 | — | — | WO | disclosed |
| US-20100075926-A1 | ACTIVATION OF HISTONE DEACETYLASE 1 (HDAC1) PROTECTS AGAINST DNA DAMAGE AND INCREASES NEURONAL SURVIVAL | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2010-03-25 | — | — | US | disclosed |
| WO-2010030395-A2 | WITHAFERIN A ANALOGS AND USES THEREOF | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2010-03-18 | — | — | WO | disclosed |
| WO-2010027334-A1 | NOVEL TRICYCLIC CHIRAL COMPOUNDS AND THEIR USE IN ASYMMETRIC CATALYSIS | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2010-03-11 | — | — | WO | disclosed |
| WO-2010028362-A1 | POLYCARBONATE POLYOL COMPOSITIONS AND METHODS | NOVOMER, INC. (US) | 2010-03-11 | — | — | WO | disclosed |
| WO-2010024930-A2 | CORTISTATIN ANALOGUES AND SYNTHESES THEROF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2010-03-04 | — | — | WO | disclosed |
| WO-2010022388-A2 | CATALYSTS AND METHODS FOR POLYMER SYNTHESIS | NOVOMER, INC. (US) | 2010-02-25 | — | — | WO | disclosed |
| WO-2010019210-A2 | HALOFUGINONE ANALOGS FOR INHIBITION OF TRNA SYNTHETASES AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2010-02-18 | — | — | WO | disclosed |
| WO-2010011313-A2 | LIGATION OF STAPLED POLYPEPTIDES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2010-01-28 | — | — | WO | disclosed |
| WO-2010011318-A2 | ACTIVATIQN OF HISTONE DEACETYLASE 1 (HDAC1) PROTECTS AGAINST DNA DAMAGE AND INCREASES NEURONAL SURVIVAL | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2010-01-28 | — | — | WO | disclosed |
| WO-2010009403-A2 | METHODS FOR TREATING ARTHRITIS AND OTHER INFLAMMATORY OR AUTOIMMUNE DISEASES | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2010-01-21 | — | — | WO | disclosed |
| US-20100015130-A1 | DISC-1 PATHWAY ACTIVATORS IN THE CONTROL OF NEUROGENESIS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2010-01-21 | — | — | US | disclosed |
| WO-2010006343-A2 | GLYCOPEPTIDE CONSTRUCTS AND USES THEREOF | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2010-01-14 | — | — | WO | disclosed |
| US-20100010012-A1 | GLUTAMATE AGGRECANASE INHIBITORS | WYETH (US) | 2010-01-14 | — | — | US | disclosed |
| EP-2142562-A2 | STITCHED POLYPEPTIDES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2010-01-13 | — | — | EP | disclosed |
| WO-2009153769-A1 | A BIOMATERIAL | VYSERA BIOMEDICAL LIMITED (IE) | 2009-12-23 | — | — | WO | disclosed |
| WO-2009153770-A1 | ESOPHAGEAL VALVE | VYSERA BIOMEDICAL LIMITED (IE) | 2009-12-23 | — | — | WO | disclosed |
| WO-2009153771-A1 | ESOPHAGEAL VALVE | VYSERA BIOMEDICAL LIMITED (IE) | 2009-12-23 | — | — | WO | disclosed |
| WO-2009153768-A1 | ESOPHAGEAL VALVE | VYSΕRA BIOMEDICAL LIMITED (IE) | 2009-12-23 | — | — | WO | disclosed |
| WO-2009151561-A2 | METHODS AND COMPOUNDS FOR ANTIMICROBIAL INTERVENTION | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2009-12-17 | — | — | WO | disclosed |
| WO-2009151683-A2 | QUINOLINONE FARNESYL TRANSFERASE INHIBITORS FOR THE TREATMENT OF SYNUCLEINOPATHIES AND OTHER INDICATIONS | LINK MEDICINE CORPORATION (US) | 2009-12-17 | — | — | WO | disclosed |
| WO-2009149347-A1 | HIGH-VALENT PALLADIUM FLUORIDE COMPLEXES AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2009-12-10 | — | — | WO | disclosed |
| US-20090302842-A1 | BIRADICAL POLARIZING AGENTS FOR DYNAMIC NUCLEAR POLARIZATION | MASSACHUSETTS INSTITUTE OF TECNOLOGY (US) | 2009-12-10 | — | — | US | disclosed |
| WO-2009132051-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR MAKING THE SAME | SIGNUM BIOSCIENCES, INC. (US) | 2009-10-29 | — | — | WO | disclosed |
| WO-2009132032-A2 | SONIC HEDGEHOG MODULATORS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2009-10-29 | — | — | WO | disclosed |
| US-20090264496-A1 | Compounds, Compositions and Methods for Making the Same | SIGNUM BIOSCIENCES, INC. | 2009-10-22 | — | — | US | disclosed |
| WO-2009126737-A2 | TRITERPENE SAPONINS, METHODS OF SYNTHESIS, AND USES THEREOF | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2009-10-15 | — | — | WO | disclosed |
| US-20090253655-A1 | QUINOLINONE FARNESYL TRANSFERASE INHIBITORS FOR THE TREATMENT OF SYNUCLEINOPATHIES AND OTHER INDICATIONS | ASTRAZENECA AB (SE) | 2009-10-08 | — | — | US | disclosed |
| US-20090221568-A1 | Synthesis of Inhibitors of FtsZ | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-09-03 | — | — | US | disclosed |
| US-7582636-B2 | Piperazinylimidazopyridine and piperazinyltriazolopyridine antagonists of Gonadotropin Releasing Hormone receptor | WYETH (US) | 2009-09-01 | — | — | US | disclosed |
| US-7582634-B2 | 7-substituted imidazo[4,5-c]pyridine antagonists of gonadotropin releasing hormone receptor | WYETH (US) | 2009-09-01 | — | — | US | disclosed |
| WO-2009100014-A1 | SYSTEM FOR FLUORINATING ORGANIC COMPOUNDS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2009-08-13 | — | — | WO | disclosed |
| WO-2009097332-A2 | THERAPEUTIC COMPOSITIONS | SHIRE HUMAN GENETIC THERAPIES, INC. (US) | 2009-08-06 | — | — | WO | disclosed |
| EP-1912679-A4 | AMINE-CONTAINING LIPIDS AND USES THEREOF | MASSACHUSETTS INST TECHNOLOGY (US) | 2009-07-29 | — | — | EP | disclosed |
| US-20090186940-A1 | Synthesis of Scabronines and Analogues Thereof | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH | 2009-07-23 | — | — | US | disclosed |
| EP-2076133-A2 | SYNTHESIS OF ENONE INTERMEDIATE | The President and Fellows of Harvard College (US) | 2009-07-08 | — | — | EP | disclosed |
| EP-1753713-A4 | SYNTHESIS OF TETRACYCLINES AND ANALOGUES THEREOF | HARVARD COLLEGE (US) | 2009-07-08 | — | — | EP | disclosed |
| EP-1664016-B9 | THERAPEUTIC AGENTS USEFUL FOR TREATING PAIN | EURO CELTIQUE SA (LU) | 2009-07-08 | — | — | EP | disclosed |
| US-20090170805-A1 | ANTI-MICROBIAL AGENTS AND USES THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-07-02 | — | — | US | disclosed |
| EP-2073816-A2 | INHIBITORS OF FATTY ACID AMIDE HYDROLASE | Infinity Pharmaceuticals, Inc. (US) | 2009-07-01 | — | — | EP | disclosed |
| US-7553873-B2 | Glutamate aggrecanase inhibitors | WYETH (US) | 2009-06-30 | — | — | US | disclosed |
| WO-2009042270-A9 | RECA INHIBITORS AND THEIR USES AS MICROBIAL INHIBITORS OR POTENTIATORS OF ANTIBIOTIC ACTIVITY | UNIV BOSTON (US) | 2009-06-18 | — | — | WO | disclosed |
| US-20090143581-A1 | SYNTHESIS OF AVRAINVILLAMIDE, STREPHACIDIN B, AND ANALOGUES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2009-06-04 | — | — | US | disclosed |
| US-7541485-B2 | Methods for preparing glutamic acid derivatives | WYETH (US) | 2009-06-02 | — | — | US | disclosed |
| US-7538113-B2 | 4-substituted imidazo[4,5-c]pyridine antagonists of gonadotropin releasing hormone receptor | WYETH (US) | 2009-05-26 | — | — | US | disclosed |
| US-7534796-B2 | Imidazo[4,5-b]pyridine antagonists of gonadotropin releasing hormone receptor | WYETH (US) | 2009-05-19 | — | — | US | disclosed |
| US-7531542-B2 | Benzooxazole and benzothiazole antagonists of gonadotropin releasing hormone receptor | WYETH (US) | 2009-05-12 | — | — | US | disclosed |
| US-20090099131-A1 | INHIBITORS OF FATTY ACID AMIDE HYDROLASE | INFINITY DISCOVERY, INC. (US) | 2009-04-16 | — | — | US | disclosed |
| US-20090093640-A1 | modular synthesis of tetracycline analogs through a chiral enone intermediate; efficiency | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-04-09 | — | — | US | disclosed |
| WO-2009046314-A2 | MOENOMYCIN ANALOGS, METHODS OF SYNTHESIS, AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2009-04-09 | — | — | WO | disclosed |
| WO-2009042972-A1 | FLUORINATED LIPIDS AND METHODS OF USE | TUFTS UNIVERSITY (US) | 2009-04-02 | — | — | WO | disclosed |
| WO-2009042270-A2 | RECA INHIBITORS AND THEIR USES AS MICROBIAL INHIBITORS OR POTENTIATORS OF ANTIBIOTIC ACTIVITY | TRUSTEES OF BOSTON UNIVERSITY (US) | 2009-04-02 | — | — | WO | disclosed |
| WO-2009036275-A1 | TREATMENT OF NEURODEGENERATIVE DISEASES USING INDATRALINE ANALOGS | LINK MEDICINE CORPORATION (US) | 2009-03-19 | — | — | WO | disclosed |
| WO-2009026444-A1 | RYANODINE CHANNEL BINDERS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2009-02-26 | — | — | WO | disclosed |
| EP-2024326-A2 | METHODS FOR PREPARING GLUTAMIC ACID DERIVATIVES AND INTERMEDIATES THEREOF | Wyeth (US) | 2009-02-18 | — | — | EP | disclosed |
| EP-1727801-B1 | PIPERAZINES USEFUL FOR TREATING PAIN | EURO CELTIQUE SA (LU) | 2009-02-18 | — | — | EP | disclosed |
| WO-2009020768-A1 | TARGETING THE ONCOPROTEIN NUCLEOPHOSMIN | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2009-02-12 | — | — | WO | disclosed |
| US-20090042902-A1 | THERAPEUTIC AGENTS USEFUL FOR TREATING PAIN | PURDUE PHARMA L.P. (US) | 2009-02-12 | — | — | US | disclosed |
| WO-2009018088-A2 | IMAGING OF ALPHA-SYNUCLEIN | LINK MEDICINE CORPORATION (US) | 2009-02-05 | — | — | WO | disclosed |
| EP-2018545-A2 | BIRADICAL POLARIZING AGENTS FOR DYNAMIC NUCLEAR POLARIZATION | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2009-01-28 | — | — | EP | disclosed |
| EP-2017276-A1 | Phenyl-carboxamide compounds useful for treating pain | EURO-CELTIQUE S.A. (LU) | 2009-01-21 | — | — | EP | disclosed |
| EP-2016044-A2 | SYNTHESIS OF TETRACYCLINES AND ANALOGUES THEREOF | The President and Fellows of Harvard College (US) | 2009-01-21 | — | — | EP | disclosed |
| WO-2008144507-A2 | SPIROOXINDOLE INHIBITORS OF AURORA KINASE | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2008-11-27 | — | — | WO | disclosed |
| WO-2008144514-A2 | POLYOL-BASED POLYMERS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2008-11-27 | — | — | WO | disclosed |
| WO-2008137692-A1 | TREATMENT OF SYNUCLEINOPATHIES | LINK MEDICINE CORPORATION (US) | 2008-11-13 | — | — | WO | disclosed |
| EP-1664016-B1 | THERAPEUTIC AGENTS USEFUL FOR TREATING PAIN | EURO CELTIQUE SA (LU) | 2008-10-29 | — | — | EP | disclosed |
| US-20080262228-A1 | Metabolites of 5-fluoro-8- quinoline and methods of preparation and uses thereof | WYETH (US) | 2008-10-23 | — | — | US | disclosed |
| WO-2008127361-A2 | SYNTHESIS OF ENONE INTERMEDIATE | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2008-10-23 | — | — | WO | disclosed |
| WO-2008124571-A2 | ANTI-VIRAL COMPOUNDS, COMPOSITIONS AND METHODS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2008-10-16 | — | — | WO | disclosed |
| WO-2008121767-A2 | STITCHED POLYPEPTIDES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2008-10-09 | — | — | WO | disclosed |
| WO-2008122038-A1 | REGULATING AUTOPHAGY | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2008-10-09 | — | — | WO | disclosed |
| WO-2008119015-A2 | SYNTHESIS OF THIOHYDANTOINS | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2008-10-02 | — | — | WO | disclosed |
| EP-1957474-A1 | SYNTHESIS OF INHIBITORS OF FTSZ | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2008-08-20 | — | — | EP | disclosed |
| EP-1664041-B1 | PHENYL-CARBOXAMIDE COMPOUNDS USEFUL FOR TREATING PAIN | EURO CELTIQUE SA (LU) | 2008-07-02 | — | — | EP | disclosed |
| EP-1934171-A1 | METHODS FOR PREPARING GLUTAMIC ACID DERIVATIVES | Wyeth a Corporation of the State of Delaware (US) | 2008-06-25 | — | — | EP | disclosed |
| US-20080139546-A1 | Tetrahydroquinoline, indoline, and related aniline derivatives of heterocycle-fused benzodioxan methylamines | WYETH (US) | 2008-06-12 | — | — | US | disclosed |
| WO-2008063300-A2 | BORONIC ACIDS AND ESTERS AS INHIBITORS OF FATTY ACID AMIDE HYDROLASE | INFINITY PHARMACEUTICALS, INC. (US) | 2008-05-29 | — | — | WO | disclosed |
| US-20080119670-A1 | Methods for preparing glutamic acid derivatives and intermediates thereof | WYETH (US) | 2008-05-22 | — | — | US | disclosed |
| WO-2008048714-A2 | BIRADICAL POLARIZING AGENTS FOR DYNAMIC NUCLEAR POLARIZATION | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2008-04-24 | — | — | WO | disclosed |
| EP-1912679-A2 | AMINE-CONTAINING LIPIDS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007117639-A9 | SYNTHESIS OF TETRACYCLINES AND ANALOGUES THEREOF | HARVARD COLLEGE (US) | 2008-04-17 | — | — | WO | disclosed |
| WO-2008042735-A1 | TETRAHYDROQUINOLINE, INDOLINE, AND RELATED ANILINE DERIVATIVES OF HETEROCYCLE-FUSED BENZODIOXAN METHYLAMINES | WYETH (US) | 2008-04-10 | — | — | WO | disclosed |
| EP-1902014-A2 | GLUTAMATE AGGRECANASE INHIBITORS | Wyeth (US) | 2008-03-26 | — | — | EP | disclosed |
| WO-2008028057-A2 | SHIKIMIC ACID-DERIVED COMPOUNDS FOR INHIBITION AND DETECTION OF AURORA A-ASSOCIATED TUMORS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2008-03-06 | — | — | WO | disclosed |
| WO-2007143014-A2 | METHODS FOR PREPARING GLUTAMIC ACID DERIVATIVES AND INTERMEDIATES THEREOF | WYETH (US) | 2007-12-13 | — | — | WO | disclosed |
| EP-1863800-A2 | SYNTHESIS OF AVRAINVILLAMIDE, STEPHACIDIN B, AND ANALOGUES THEREOF | The President and Fellows of Harvard College (US) | 2007-12-12 | — | — | EP | disclosed |
| WO-2007117639-A2 | SYNTHESIS OF TETRACYCLINES AND ANALOGUES THEREOF | THE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2007-10-18 | — | — | WO | disclosed |
| EP-1810970-A1 | Therapeutic piperazine compounds | EURO-CELTIQUE S.A. (LU) | 2007-07-25 | — | — | EP | disclosed |
| US-20070142360-A1 | Therapeutic agents useful for treating pain | EURO-CELTIQUE S.A. | 2007-06-21 | — | — | US | disclosed |
| WO-2007062314-A2 | HETEROCYCLIC CETP INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-05-31 | — | — | WO | disclosed |
| WO-2007056188-A1 | SYNTHESIS OF INHIBITORS OF FTSZ | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2007-05-18 | — | — | WO | disclosed |
| US-20070088172-A1 | Methods for preparing glutamic acid derivatives | WYETH (US) | 2007-04-19 | — | — | US | disclosed |
| WO-2007044100-A1 | METHODS FOR PREPARING GLUTAMIC ACID DERIVATIVES | WYETH (US) | 2007-04-19 | — | — | WO | disclosed |
| US-20070066851-A1 | Palladium-catalyzed carbon-carbon bond forming reactions | NAVY, SECRETARY OF THE UNITED STATES OF AMERICA | 2007-03-22 | — | — | US | disclosed |
| EP-1562936-B1 | THERAPEUTIC PIPERAZINE COMPOUNDS | EURO CELTIQUE SA (LU) | 2007-03-14 | — | — | EP | disclosed |
| US-20070043066-A1 | Glutamate aggrecanase inhibitors | WYETH (US) | 2007-02-22 | — | — | US | disclosed |
| EP-1753713-A2 | SYNTHESIS OF TETRACYCLINES AND ANALOGUES THEREOF | The President and Fellows of Harvard College (US) | 2007-02-21 | — | — | EP | disclosed |
| US-20070032500-A1 | Therapeutic agents useful for treating pain | PURDUE PHARMA L.P. | 2007-02-08 | — | — | US | disclosed |
| WO-2007013965-A2 | SYNTHESIS OF SCABRONINES AND ANALOGUES THEREOF | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2007-02-01 | — | — | WO | disclosed |
| WO-2007008994-A2 | GLUTAMATE AGGRECANASE INHIBITORS | WYETH (US) | 2007-01-18 | — | — | WO | disclosed |
| US-7157462-B2 | Therapeutic agents useful for treating pain | EURO-CELTIQUE S.A. (LU) | 2007-01-02 | — | — | US | disclosed |
| WO-2006138380-A2 | AMINE-CONTAINING LIPIDS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2006-12-28 | — | — | WO | disclosed |
| US-20060287520-A1 | Synthesis of salinosporamide A and analogues thereof | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2006-12-21 | — | — | US | disclosed |
| CN-1882524-A | 4- ((phenoxyalkyl) thio) -phenoxyacetic acids and analogs | JANSSEN PHARMACEUTICA NV (BE) | 2006-12-20 | — | — | CN | disclosed |
| EP-1727801-A1 | PIPERAZINES USEFUL FOR TREATING PAIN | EURO-CELTIQUE S.A. (LU) | 2006-12-06 | — | — | EP | disclosed |
| US-20060270848-A1 | Piperazinylimidazopyridine and piperazinyltriazolopyridine antagonists of gonadotropin releasing hormone receptor | WYETH (US) | 2006-11-30 | — | — | US | disclosed |
| US-20060270855-A1 | Methods of preparing retroviral proteases inhibitor intermediates | G.D. SEARLE & CO. (US) | 2006-11-30 | — | — | US | disclosed |
| WO-2006124902-A2 | SYNTHESIS OF SALINOSPORAMIDE A AND ANALOGUES THEREOF | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2006-11-23 | — | — | WO | disclosed |
| US-20060264631-A1 | Benzooxazole and benzothiazole antagonists of gonadotropin releasing hormone receptor | WYETH (US) | 2006-11-23 | — | — | US | disclosed |
| WO-2006113615-A2 | ANTI-MICROBIAL AGENTS AND USES THEREOF | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2006-10-26 | — | — | WO | disclosed |
| US-20060241117-A1 | Therapeutic agents useful for treating pain | PURDUE PHARMA L.P. | 2006-10-26 | — | — | US | disclosed |
| US-20060235022-A1 | Therapeutic agents useful for treating pain | PURDUE PHARMA L.P. | 2006-10-19 | — | — | US | disclosed |
| WO-2006102097-A2 | SYNTHESIS OF AVRAINVILLAMIDE, STEPHACIDIN B, AND ANALOGUES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2006-09-28 | — | — | WO | disclosed |
| US-20060189618-A1 | 4-Substituted imidazo[4,5-c]pyridine antagonists of gonadotropin releasing hormone receptor | WYETH (US) | 2006-08-24 | — | — | US | disclosed |
| US-20060189616-A1 | 7-Substituted imidazo[4,5-c]pyridine antagonists of gonadotropin releasing hormone receptor | WYETH (US) | 2006-08-24 | — | — | US | disclosed |
| US-20060189617-A1 | Imidazo[4,5-b]pyridine antagonists of gonadotropin releasing hormone receptor | WYETH (US) | 2006-08-24 | — | — | US | disclosed |
| US-7060851-B2 | Method of preparing retroviral protease inhibitor intermediates | G.D. SEARLE & CO. (US) | 2006-06-13 | — | — | US | disclosed |
| EP-1664016-A2 | THERAPEUTIC AGENTS USEFUL FOR TREATING PAIN | Euro-Celtique S.A. (LU) | 2006-06-07 | — | — | EP | disclosed |
| EP-1664041-A1 | PHENYL-CARBOXAMIDE COMPOUNDS USEFUL FOR TREATING PAIN | Euro-Celtique S.A. (LU) | 2006-06-07 | — | — | EP | disclosed |
| US-20050282787-A1 | Synthesis of tetracyclines and analogues thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2005-12-22 | — | — | US | disclosed |
| WO-2005112945-A2 | SYNTHESIS OF TETRACYCLINES AND ANALOGUES THEREOF | THE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2005-12-01 | — | — | WO | disclosed |
| EP-1562936-A2 | THERAPEUTIC PIPERAZINE COMPOUNDS | Euro-Celtique, S.A. (LU) | 2005-08-17 | — | — | EP | disclosed |
| WO-2005066130-A1 | PIPERAZINES USEFUL FOR TREATING PAIN | EURO-CELTIQUE S.A. (LU) | 2005-07-21 | — | — | WO | disclosed |
| WO-2005056524-A2 | THERAPEUTIC AGENTS USEFUL FOR TREATING PAIN | EURO-CELTIQUE S.A. (LU) | 2005-06-23 | — | — | WO | disclosed |
| US-20050131075-A1 | Method of preparing retroviral protease inhibitor intermediates | G.D. SEARLE & CO. (US) | 2005-06-16 | — | — | US | disclosed |
| WO-2005035500-A2 | THERAPEUTIC AGENTS USEFUL FOR TREATING PAIN | EURO-CELTIQUE S.A. (LU) | 2005-04-21 | — | — | WO | disclosed |
| WO-2005030753-A2 | THERAPEUTIC AGENTS USEFUL FOR TREATING PAIN | EURO-CELTIQUE S.A. (LU) | 2005-04-07 | — | — | WO | disclosed |
| WO-2005030766-A1 | PHENYL - CARBOXAMIDE COMPOUNDS USEFUL FOR TREATING PAIN | EURO-CELTIQUE S.A. (LU) | 2005-04-07 | — | — | WO | disclosed |
| US-20050059671-A1 | Therapeutic agents useful for treating pain | PURDUE PHARMA L.P. | 2005-03-17 | — | — | US | disclosed |
| US-6849760-B2 | Method of preparing retroviral protease inhibitor intermediates | G. D. SEARLE & CO. (US) | 2005-02-01 | — | — | US | disclosed |
| WO-2004029031-A2 | THERAPEUTIC PIPERAZINE COMPOUNDS | EURO-CELTQUE, S.A. (LU) | 2004-04-08 | — | — | WO | disclosed |
| EP-0970066-B1 | Preparation of aminoepoxides from aminoaldehydes and an in situ formed halomethyl organometallic reagent | SEARLE & CO (US) | 2003-09-17 | — | — | EP | disclosed |
| US-20030171612-A1 | Method of preparing retroviral protease inhibitor intermediates | G.D. SEARLE & CO. | 2003-09-11 | — | — | US | disclosed |
| US-6515162-B2 | Precipitating or crystallizing a salt from solution; suitable as intermediates for large scale production of enzyme inhibitors, e.g. hydroxyethylamine, hydroxyethylurea and hydroxyethylsulfonamide | G.D. SEARLE & CO. | 2003-02-04 | — | — | US | disclosed |
| EP-0855388-B1 | Method for making intermediates useful in synthesis of retroviral protease inhibitors | SEARLE & CO (US) | 2002-03-06 | — | — | EP | disclosed |
| US-20010047111-A1 | Method of preparing retroviral protease inhibitor intermediates | NG JOHN S (US) | 2001-11-29 | — | — | US | disclosed |
| EP-0804410-B1 | METHOD OF PREPARING RETROVIRAL PROTEASE INHIBITOR INTERMEDIATES | SEARLE & CO (US) | 2001-08-29 | — | — | EP | disclosed |
| US-6201150-B1 | DIASTEREOMER PURIFICATION METHOD COMPRISING PREPARING AN ORGANIC ACID OR INORGANIC ACID SALT OF AN AMINO COMPOUND AND PRECIPITATING OR CRYSTALLIZING SAID SALT FROM A SOLUTION | G.D. SEARLE & CO. | 2001-03-13 | — | — | US | disclosed |
| US-6127556-A | Epoxide formation by continuous in-situ synthesis process | G. D. SEARLE & CO. (US) | 2000-10-03 | — | — | US | disclosed |
| EP-0730570-B1 | METHOD FOR MAKING INTERMEDIATES USEFUL IN SYNTHESIS OF RETROVIRAL PROTEASE INHIBITORS | SEARLE & CO (US) | 2000-04-19 | — | — | EP | disclosed |
| EP-0970066-A1 | AMINOEPOXIDES FROM AMINOALDEHYDES AND IN-SITU FORMED HALOMETHYL ORGANOMETALLIC REAGENT | G.D. SEARLE & CO. (US) | 2000-01-12 | — | — | EP | disclosed |
| US-5872299-A | Method of preparing intermediates for retroviral protease inhibitors | G. D. SEARLE & CO. (US) | 1999-02-16 | — | — | US | disclosed |
| US-5872298-A | Method of preparing intermediates for retroviral protease inhibitors | G. D. SEARLE & CO. (US) | 1999-02-16 | — | — | US | disclosed |
| US-5831117-A | ACID SALTS | G. D. SEARLE & CO. (US) | 1998-11-03 | — | — | US | disclosed |
| EP-0855388-A2 | Method for making intermediates useful in synthesis of retroviral protease inhibitors | G.D. SEARLE & CO. (US) | 1998-07-29 | — | — | EP | disclosed |
| WO-1998029401-A1 | AMINOEPOXIDES FROM AMINOALDEHYDES AND IN-SITU FORMED HALOMETHYL ORGANOMETALLIC REAGENT | G.D. SEARLE & CO. (US) | 1998-07-09 | — | — | WO | disclosed |
| EP-0804410-A1 | METHOD OF PREPARING RETROVIRAL PROTEASE INHIBITOR INTERMEDIATES | G.D. SEARLE & CO. (US) | 1997-11-05 | — | — | EP | disclosed |
| US-5648511-A | Method for making intermediates useful in the synthesis of retroviral protease inhibitors | G.D. SEARLE & CO. (US) | 1997-07-15 | — | — | US | disclosed |
| EP-0730570-A1 | METHOD FOR MAKING INTERMEDIATES USEFUL IN SYNTHESIS OF RETROVIRAL PROTEASE INHIBITORS | G.D. SEARLE & CO. (US) | 1996-09-11 | — | — | EP | disclosed |
| WO-1996022275-A1 | METHOD OF PREPARING RETROVIRAL PROTEASE INHIBITOR INTERMEDIATES | G.D. SEARLE & CO. (US) | 1996-07-25 | — | — | WO | disclosed |
| WO-1995014653-A1 | METHOD FOR MAKING INTERMEDIATES USEFUL IN SYNTHESIS OF RETROVIRAL PROTEASE INHIBITORS | G.D. SEARLE & CO. (US) | 1995-06-01 | — | — | WO | disclosed |
| WO-1995014653-A1 | METHOD FOR MAKING INTERMEDIATES USEFUL IN SYNTHESIS OF RETROVIRAL PROTEASE INHIBITORS | G.D. SEARLE & CO. (US) | 1995-06-01 | — | — | WO | disclosed |