Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL291087 | 0.80 | THRB (0.35) | THRB | |
| SCHEMBL11146755 | 0.79 | CA4 (0.35) | THRB | |
| SCHEMBL56282 | 0.78 | THRB (0.33) | THRB | |
| SCHEMBL291088 | 0.78 | ALDH1A1 (0.33) | THRB | |
| SCHEMBL13434035 | 0.78 | GAA (0.42) | THRB | |
| SCHEMBL20109904 | 0.76 | ELANE (0.32) | THRB | |
| SCHEMBL80733 | 0.76 | LMNA (0.35) | THRB | |
| SCHEMBL16823234 | 0.76 | THRB (0.32) | THRB | |
| SCHEMBL13201625 | 0.74 | THRB (0.30) | THRB | |
| SCHEMBL8819950 | 0.74 | L3MBTL1 (0.35) | THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7427679-B2 | Precursors for two-step polynucleotide synthesis | AGILENT TECHNOLOGIES, INC. (US) | 2008-09-23 | — | — | US | disclosed |
| US-7417139-B2 | Method for polynucleotide synthesis | AGILENT TECHNOLOGIES, INC. (US) | 2008-08-26 | — | — | US | disclosed |
| US-7193077-B2 | Exocyclic amine triaryl methyl protecting groups in two-step polynucleotide synthesis | AGILENT TECHNOLOGIES, INC. (US) | 2007-03-20 | — | — | US | disclosed |
| EP-1512691-A1 | Protecting groups for two-step polynucleotide synthesis | Agilent Technologies Inc (US) | 2005-03-09 | — | — | EP | disclosed |
| US-20050048601-A1 | Method for polynucleotide synthesis | REGENTS OF THE UNIVERSITY OF COLORADO, THE | 2005-03-03 | — | — | US | disclosed |
| US-20050049411-A1 | Exocyclic amine triaryl methyl protecting groups in two step polynucleotide synthesis | REGENTS OF THE UNIVERSITY OF COLORADO, THE | 2005-03-03 | — | — | US | disclosed |
| US-20050049407-A1 | Precursors for two-step polynucleotide synthesis | THE REGENTS OF THE UNIVERSITY OF COLORADO | 2005-03-03 | — | — | US | disclosed |
| EP-1510523-A1 | Precurors for two-step polynucleotide synthesis | Agilent Technologies Inc (US) | 2005-03-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050048601-A1 | Method for polynucleotide synthesis | POLN, RNGTT, NSUN2 | THRB 3282/4885 |
| US-20050049407-A1 | Precursors for two-step polynucleotide synthesis | NT5C3B, NSUN2, POLN | THRB 2671/4885 |
| US-20050049411-A1 | Exocyclic amine triaryl methyl protecting groups in two step polynucleotide synthesis | NT5C3B, RNMT, NSUN2 | THRB 2067/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.