SCHEMBL291087

SCHEMBL291087

CC(C)(OC(=O)OC(C)(C)C(Cl)(Cl)Cl)C(Cl)(Cl)Cl

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8819950 0.87 L3MBTL1 (0.35) THRBL3MBTL1
SCHEMBL1128473 0.81
SCHEMBL5015809 0.80 THRB (0.33) THRB
SCHEMBL56282 0.80 THRB (0.33) THRB
SCHEMBL13434035 0.80 GAA (0.42) THRB
SCHEMBL291088 0.80 ALDH1A1 (0.33) THRB
SCHEMBL16823234 0.78 THRB (0.32) THRB
SCHEMBL80733 0.78 LMNA (0.35) THRB
SCHEMBL20109904 0.78 ELANE (0.32) THRB
SCHEMBL13201625 0.76 THRB (0.30) THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 271 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2727915-B1 Synthesis of deuterated catechols and benzo[d][1,3]dioxoles and derivatives thereof CONCERT PHARMACEUTICALS INC (US) 2016-04-13 EP claimed
EP-2727915-A1 Synthesis of deuterated catechols and benzo[d][1,3]dioxoles and derivatives thereof Concert Pharmaceuticals Inc. (US) 2014-05-07 EP claimed
EP-3494996-B1 ANTIBODY DRUG CONJUGATES (ADC) THAT BIND TO 158P1D7 PROTEINS AGENSYS INC (US) 2026-04-15 EP disclosed
US-20260000604-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING ANTI-191P4D12 ANTIBODY DRUG CONJUGATES AND METHODS OF USE THEREOF AGENSYS, INC. (US) 2026-01-01 US disclosed
US-12496353-B2 Synergistic effects between auristatin-based antibody drug conjugates and inhibitors of the PI3K-AKT mTOR pathway SEAGEN INC. (US) 2025-12-16 US disclosed
EP-4419513-B1 ANTITUMORAL COMPOUNDS PHARMA MAR SA (ES) 2025-08-27 EP disclosed
US-12384800-B2 Antitumoral compounds PHARMA MAR, S.A. (ES) 2025-08-12 US disclosed
US-20250243174-A1 ANTITUMORAL COMPOUNDS PHARMA MAR, S.A. (ES) 2025-07-31 US disclosed
US-12257340-B2 Pharmaceutical compositions comprising anti-191P4D12 antibody drug conjugates and methods of use thereof AGENSYS, INC. (US) 2025-03-25 US disclosed
WO-2025050647-A1 IONIZABLE CATIONIC LIPID COMPOUNDS AS WELL AS PREPARATION METHOD THEREFOR AND USE THEREOF 晟迪生物医药(苏州)有限公司 2025-03-13 WO disclosed
US-12215100-B2 Anticancer compounds PHARMA MAR, S.A. (ES) 2025-02-04 US disclosed
US-6399590-B2 REPERFUSION INJURY; 2-DEOXY-6-O-(2-DEOXY-4-O-PHOSPHONO-3-O-(3-TETRADECANOYLOXYTETRADECANOYL) -2-(3-OCTADECANOYLOXY-TETRADECANOYLAMINO)-BETA-D-GLUCOPYRANOSYL)-2-(3 -HEXADECANOYLOXYTETRADECANOYLAMINO)-D-GLUCOPYRANOSE CORIXA CORPORATION 2002-06-04 US disclosed
US-20020048588-A1 Aminoalkyl glucosaminide phosphate compounds and their use as adjuvants and immunoeffectors CORIXA CORPORATION 2002-04-25 US disclosed
US-6355257-B1 Aminoalkyl glucosamine phosphate compounds and their use as adjuvants and immunoeffectors CORIXA CORPORATION 2002-03-12 US disclosed
US-20020013291-A1 Phosphoglycolipid and methods for its use CORIXA CORPORATION 2002-01-31 US disclosed
US-6303347-B1 VACCINES CORIXA CORPORATION 2001-10-16 US disclosed
US-6113918-A IMMUNOLOGY RIBI IMMUNOCHEM RESEARCH, INC. (US) 2000-09-05 US disclosed
EP-0983286-A1 AMINOALKYL GLUCOSAMINE PHOSPHATE COMPOUNDS AND THEIR USE AS ADJUVANTS AND IMMUNOEFFECTORS CORIXA CORPORATION (US) 2000-03-08 EP disclosed
US-6013640-A ANTIISCHEMIC AGENTS RIBI IMMUNOCHEM RESEARCH, INC. (US) 2000-01-11 US disclosed
WO-1998050399-A1 AMINOALKYL GLUCOSAMINE PHOSPHATE COMPOUNDS AND THEIR USE AS ADJUVANTS AND IMMUNOEFFECTORS CORIXA CORPORATION (US) 1998-11-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12496353-B2 Synergistic effects between auristatin-based antibody drug conjugates and inhibitors of the PI3K-AKT mTOR pathway MTOR, RICTOR, PIK3R5 THRB 2976/4885L3MBTL1 3352/4885
US-12384800-B2 Antitumoral compounds TP53, TOP1, MCL1 THRB 4578/4885L3MBTL1 4215/4885
US-20260000604-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING ANTI-191P4D12 ANTIBODY DRUG CONJUGATES AND METHODS OF USE THEREOF CD44, CA12, H1-10 THRB 1052/4885L3MBTL1 1425/4885
US-20250243174-A1 ANTITUMORAL COMPOUNDS MCL1, XPOT, GZMB THRB 4496/4885L3MBTL1 1938/4885
US-20020048588-A1 Aminoalkyl glucosaminide phosphate compounds and their use as adjuvants and immunoeffectors DNPEP, CD68, MGAT3 THRB 2791/4885L3MBTL1 3770/4885
US-20020013291-A1 Phosphoglycolipid and methods for its use PYGL, GPI, PNLIP THRB 3560/4885L3MBTL1 635/4885
US-12257340-B2 Pharmaceutical compositions comprising anti-191P4D12 antibody drug conjugates and methods of use thereof TMED10, CD44, CA12 THRB 3416/4885L3MBTL1 3084/4885
US-12215100-B2 Anticancer compounds TP53, MCL1, MYC THRB 4141/4885L3MBTL1 1434/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.