Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8066042 | 0.78 | HSD17B1 (0.33) | HSD17B1 | |
| SCHEMBL3678973 | 0.76 | AR (0.47) | AR | |
| SCHEMBL8074381 | 0.75 | RXRA (0.34) | RXRARXRBRXRG | |
| SCHEMBL10916725 | 0.74 | HSD17B1 (0.45) | RXRARXRBHSD17B1AR | |
| SCHEMBL2431524 | 0.74 | PDK2 (0.35) | AR | |
| SCHEMBL15063608 | 0.73 | AR (0.32) | AR | |
| SCHEMBL8079296 | 0.73 | HSD17B1 (0.41) | RXRARXRBHSD17B1AR | |
| SCHEMBL8079532 | 0.73 | AR (0.33) | AR | |
| SCHEMBL2428524 | 0.73 | KIF11 (0.37) | HSD17B1 | |
| SCHEMBL16445402 | 0.73 | PTGS2 (0.31) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6166072-A | Amino acid derivatives | ALLELIX NEUROSCIENCE, INC. (CA) | 2000-12-26 | — | — | US | disclosed |