Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | RXRG | P48443 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.31 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | DAO | P14920 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8072544 | 0.80 | PKM (0.31) | — | |
| SCHEMBL8078153 | 0.77 | KIF11 (0.43) | KIF11CES2 | |
| SCHEMBL16055751 | 0.76 | NPBWR1 (0.41) | KIF11MAPT | |
| SCHEMBL12076361 | 0.75 | ABCB11 (0.36) | KIF11 | |
| SCHEMBL5897973 | 0.75 | PTPN5 (0.41) | KIF11CES2 | |
| SCHEMBL8074574 | 0.75 | RXRA (0.33) | RXRARXRBRXRG | |
| SCHEMBL11035038 | 0.75 | MAPT (0.48) | RXRARXRBRXRGMAPT | |
| SCHEMBL2015248 | 0.74 | TRPA1 (0.43) | PDE2AKIF11 | |
| SCHEMBL15133743 | 0.74 | ESR1 (0.44) | PDE2AKIF11CES2DAO | |
| SCHEMBL2204411 | 0.74 | NOTUM (0.43) | KIF11CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6166072-A | Amino acid derivatives | ALLELIX NEUROSCIENCE, INC. (CA) | 2000-12-26 | — | — | US | disclosed |