Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 2/20 | 0.36 |
| ▸ | CES1 | P23141 | 2/20 | 0.36 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.35 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 3/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL418321 | 0.90 | LTA4H (0.38) | SMN1; SMN2MEN1KMT2ACES2CES1 | |
| SCHEMBL8992386 | 0.88 | DNM1 (0.40) | SMN1; SMN2MEN1KMT2ACES2CES1 | |
| SCHEMBL9643720 | 0.88 | DNM1 (0.40) | SMN1; SMN2MEN1KMT2ACES2CES1 | |
| SCHEMBL418038 | 0.88 | DNM1 (0.40) | SMN1; SMN2MEN1KMT2ACES2CES1 | |
| SCHEMBL415280 | 0.88 | DNM1 (0.40) | SMN1; SMN2MEN1KMT2ACES2CES1 | |
| SCHEMBL417994 | 0.84 | LTA4H (0.38) | SMN1; SMN2TSHRCES2CES1PCSK9 | |
| SCHEMBL8076437 | 0.81 | AKR1B1 (0.44) | ALDH1A1HSD17B10MEN1KMT2ATSHR | |
| SCHEMBL31216290 | 0.80 | CES2 (0.38) | SMN1; SMN2MEN1KMT2ACES2CES1 | |
| SCHEMBL31216297 | 0.80 | TSHR (0.46) | SMN1; SMN2LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL10317670 | 0.79 | NPC1 (0.35) | SMN1; SMN2MEN1KMT2ACES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673942-B1 | Silacyclohexanone compounds as intermediates for the preparation of silacyclohexane-type liquid cristal compounds | SHINETSU CHEMICAL CO (JP) | 2000-11-08 | — | — | EP | disclosed |
| EP-0673942-A1 | Silacyclohexanone compounds as intermediates for the preparation of silacyclohexane-type liquid cristal compounds | Shin-Etsu Chemical Co., Ltd. (JP) | 1995-09-27 | — | — | EP | disclosed |