SCHEMBL418038

SCHEMBL418038

CCCCCC[SiH](CCCCCC)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 2/20 0.40
HTR2A P28223 1/20 0.40
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
TP53 P04637 1/20 0.39
MAPK1 P28482 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
EPHX2 P34913 1/20 0.39
PKM P14618 1/20 0.39
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
CSNK1E P49674 1/20 0.39
NAAA Q02083 3/20 0.38
HTT P42858 2/20 0.38
KCNH2 Q12809 1/20 0.38
LIPG Q9Y5X9 1/20 0.37
SIGMAR1 Q99720 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8992386 1.00 DNM1 (0.40) DNM1HTR2AMEN1KMT2ATP53
SCHEMBL415280 1.00 DNM1 (0.40) DNM1HTR2AMEN1KMT2ATP53
SCHEMBL9643720 1.00 DNM1 (0.40) DNM1HTR2AMEN1KMT2ATP53
SCHEMBL418321 0.98 LTA4H (0.38) DNM1HTR2AMEN1KMT2ATP53
SCHEMBL417994 0.91 LTA4H (0.38) DNM1TP53SMN1; SMN2CES2CES1
SCHEMBL31216297 0.91 TSHR (0.46) DNM1HTR2AMEN1KMT2ATP53
SCHEMBL31216290 0.91 CES2 (0.38) DNM1HTR2AMEN1KMT2ATP53
SCHEMBL31216272 0.89 KCNH2 (0.46) DNM1HTR2AMEN1KMT2ATP53
SCHEMBL31216298 0.89 KCNH2 (0.50) HTR2AMEN1KMT2ATP53KCNH2
SCHEMBL8076449 0.88 SMN1; SMN2 (0.39) MEN1KMT2ASMN1; SMN2CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5516871-A Diphenylsiloxane oligomers functionalized at both terminals and methods for the preparation thereof DOW CORNING ASIA, LTD. (JP) 1996-05-14 US claimed
US-5502229-A ENDCAPPING DOW CORNING ASIA, LTD. (JP) 1996-03-26 US claimed
US-11345686-B2 Aromatic amine derivative, and organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2022-05-31 US disclosed
EP-3156403-B1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO (JP) 2019-08-28 EP disclosed
US-20190177306-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2019-06-13 US disclosed
US-10246441-B2 Aromatic amine derivative, and organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2019-04-02 US disclosed
US-9972786-B2 Aromatic amine derivative, and organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2018-05-15 US disclosed
EP-3156403-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT Idemitsu Kosan Co., Ltd (JP) 2017-04-19 EP disclosed
EP-2364980-B1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO (JP) 2017-01-04 EP disclosed
US-9425402-B2 Polymerizable monomer, and material for organic device, hole injection/transport material, material for organic electroluminescence element and organic electroluminescent element each comprising polymer (polymeric compound) of the polymerizable monomer IDEMITSU KOSAN CO., LTD. (JP) 2016-08-23 US disclosed
US-9196842-B2 Aromatic amine derivative and organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2015-11-24 US disclosed
US-20110278551-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2011-11-17 US disclosed
EP-2364980-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT Idemitsu Kosan Co., Ltd. (JP) 2011-09-14 EP disclosed
US-5708168-A FOR TREATING OR PREVENTING NEURONAL LOSS STATE OF OREGON, ACTING BY AND THROUGH THE OREGON STATE BOARD OF HIGHER EDUCATION, ACTING FOR AND ON BEHALF OF THE OREGON HEALTH SCIENCES UNIVERSITY AND THE UNIVERSITY OF OREGON, EUGENE OREGON (US) 1998-01-13 US disclosed
WO-1996015112-A1 AZEPINE SYNTHESIS VIA A DIELS-ALDER REACTION ACEA PHARMACEUTICALS, INC. (US) 1996-05-23 WO disclosed
US-5502229-A ENDCAPPING DOW CORNING ASIA, LTD. (JP) 1996-03-26 US disclosed
US-5476933-A Condensation, ring expansion STATE OF OREGON, ACTING BY AND THROUGH THE OREGON STATE BOARD OF HIGHER EDUCATION, ACTING FOR AND ON BEHALF OF THE OREGON HEALTH SCIENCES UNIVERSITY AND THE UNIVERSITY OF OREGON (US) 1995-12-19 US disclosed
EP-0507223-A1 Phenyltrialkylsilane lubricating compositions ETHYL CORPORATION (US) 1992-10-07 EP disclosed
US-5124502-A Reacting sodium trialkylaluminum and phenyltrihalosilanes, controlling temperature ETHYL CORPORATION (US) 1992-06-23 US disclosed
US-5120458-A Hydraulic fluids, oxidation resistance ETHYL CORPORATION (US) 1992-06-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10246441-B2 Aromatic amine derivative, and organic electroluminescent element MAOB, MAOA, NAT1 DNM1 3282/4885HTR2A 1295/4885MEN1 1990/4885
US-20190177306-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT TYR, LEF1, EFNA1 DNM1 1413/4885HTR2A 620/4885MEN1 2298/4885
US-20110278551-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT SLC7A5, ALKBH3, TYR DNM1 2458/4885HTR2A 1170/4885MEN1 3956/4885
US-11345686-B2 Aromatic amine derivative, and organic electroluminescent element TYR, LEF1, EFNA1 DNM1 1413/4885HTR2A 620/4885MEN1 2298/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.