Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL418038 | 1.00 | DNM1 (0.40) | DNM1HTR2AMEN1KMT2ATP53 | |
| SCHEMBL415280 | 1.00 | DNM1 (0.40) | DNM1HTR2AMEN1KMT2ATP53 | |
| SCHEMBL9643720 | 1.00 | DNM1 (0.40) | DNM1HTR2AMEN1KMT2ATP53 | |
| SCHEMBL418321 | 0.98 | LTA4H (0.38) | DNM1HTR2AMEN1KMT2ATP53 | |
| SCHEMBL417994 | 0.91 | LTA4H (0.38) | DNM1TP53SMN1; SMN2CES2CES1 | |
| SCHEMBL31216297 | 0.91 | TSHR (0.46) | DNM1HTR2AMEN1KMT2ATP53 | |
| SCHEMBL31216290 | 0.91 | CES2 (0.38) | DNM1HTR2AMEN1KMT2ATP53 | |
| SCHEMBL31216272 | 0.89 | KCNH2 (0.46) | DNM1HTR2AMEN1KMT2ATP53 | |
| SCHEMBL31216298 | 0.89 | KCNH2 (0.50) | HTR2AMEN1KMT2ATP53KCNH2 | |
| SCHEMBL8076449 | 0.88 | SMN1; SMN2 (0.39) | MEN1KMT2ASMN1; SMN2CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516871-A | Diphenylsiloxane oligomers functionalized at both terminals and methods for the preparation thereof | DOW CORNING ASIA, LTD. (JP) | 1996-05-14 | — | — | US | claimed |
| US-5502229-A | ENDCAPPING | DOW CORNING ASIA, LTD. (JP) | 1996-03-26 | — | — | US | claimed |
| CN-118852230-A | Preparation method of polysubstituted hydrosilane compound | 中国科学院兰州化学物理研究所 | 2024-10-29 | — | — | CN | disclosed |
| CN-105229016-B | Pass through the saturation and unsaturation silahydrocarbons of the olefinic silane that iron and cobalt pyridine diimine are catalyzed | 莫门蒂夫性能材料股份有限公司 | 2018-11-27 | — | — | CN | disclosed |
| EP-2994474-B1 | SATURATED AND UNSATURATED SILAHYDROCARBONS VIA IRON AND COBALT PYRIDINE DIIMINE CATALYZED OLEFIN SILYLATION | MOMENTIVE PERFORMANCE MAT INC (US) | 2017-12-20 | — | — | EP | disclosed |
| US-9371339-B2 | Saturated and unsaturated silahydrocarbons via iron and cobalt pyridine diimine catalyzed olefin silylation | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2016-06-21 | — | — | US | disclosed |
| US-9371339-B2 | Saturated and unsaturated silahydrocarbons via iron and cobalt pyridine diimine catalyzed olefin silylation | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2016-06-21 | — | — | US | disclosed |
| EP-2994474-A1 | SATURATED AND UNSATURATED SILAHYDROCARBONS VIA IRON AND COBALT PYRIDINE DIIMINE CATALYZED OLEFIN SILYLATION | Momentive Performance Materials Inc. (US) | 2016-03-16 | — | — | EP | disclosed |
| CN-105229016-A | By the saturated and unsaturated silahydrocarbons of the olefinic silane of iron and the catalysis of cobalt pyridine diimine | MOMENTIVE PERFORMANCE MAT INC | 2016-01-06 | — | — | CN | disclosed |
| US-20140330036-A1 | SATURATED AND UNSATURATED SILAHYDROCARBONS VIA IRON AND COBALT PYRIDINE DIIMINE CATALYZED OLEFIN SILYLATION | PRINCETON UNIVERSITY (US) | 2014-11-06 | — | — | US | disclosed |
| US-20140330036-A1 | SATURATED AND UNSATURATED SILAHYDROCARBONS VIA IRON AND COBALT PYRIDINE DIIMINE CATALYZED OLEFIN SILYLATION | PRINCETON UNIVERSITY (US) | 2014-11-06 | — | — | US | disclosed |
| US-5516871-A | Diphenylsiloxane oligomers functionalized at both terminals and methods for the preparation thereof | DOW CORNING ASIA, LTD. (JP) | 1996-05-14 | — | — | US | disclosed |
| US-5502229-A | ENDCAPPING | DOW CORNING ASIA, LTD. (JP) | 1996-03-26 | — | — | US | disclosed |
| US-5124502-A | Reacting sodium trialkylaluminum and phenyltrihalosilanes, controlling temperature | ETHYL CORPORATION (US) | 1992-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140330036-A1 | SATURATED AND UNSATURATED SILAHYDROCARBONS VIA IRON AND COBALT PYRIDINE DIIMINE CATALYZED OLEFIN SILYLATION | YAP1, LATS1, SIK1 | DNM1 3108/4885HTR2A 3935/4885MEN1 4054/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.