Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 5/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL808332 | 0.85 | GABRA5 (0.34) | EPHX2SCN9APOLBMAPK1GABRA5 | |
| SCHEMBL808244 | 0.83 | HDAC6 (0.34) | SCN9AKCNH2SCN5A | |
| SCHEMBL10287123 | 0.80 | POLB (0.41) | SCN9APOLBMAPK1GABRA5DGAT1 | |
| SCHEMBL10287127 | 0.79 | HDAC8 (0.33) | — | |
| SCHEMBL808249 | 0.75 | HDAC4 (0.30) | — | |
| SCHEMBL10287296 | 0.74 | ATR (0.42) | POLBMAPK1ALOX5AP | |
| SCHEMBL808041 | 0.73 | TRPV1 (0.39) | — | |
| SCHEMBL808017 | 0.73 | — | — | |
| SCHEMBL10287533 | 0.72 | ADRA2A (0.33) | — | |
| SCHEMBL808036 | 0.71 | POLB (0.34) | EPHX2SCN9APOLBMAPK1GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012035023-A1 | TRIAZINE-OXADIAZOLES | NOVARTIS AG (CH) | 2012-03-22 | — | — | WO | disclosed |