Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 5/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.32 |
| ▸ | ATR | Q13535 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL807937 | 0.86 | GABRA5 (0.34) | GABRA5 | |
| SCHEMBL808036 | 0.85 | POLB (0.34) | GABRA5EPHX2POLBMAPK1SCN9A | |
| SCHEMBL807788 | 0.85 | EPHX2 (0.35) | GABRA5EPHX2POLBMAPK1SCN9A | |
| SCHEMBL10287198 | 0.84 | HDAC6 (0.34) | HDAC4HDAC8HDAC6SCN9ASCN5A | |
| SCHEMBL808161 | 0.83 | HDAC4 (0.32) | HDAC4HDAC8HDAC6 | |
| SCHEMBL10286912 | 0.83 | GABRA1 (0.36) | GABRA5HDAC4HDAC8HDAC6 | |
| SCHEMBL808331 | 0.82 | KCNH2 (0.32) | GABRA5POLBSCN9AKCNH2 | |
| SCHEMBL807787 | 0.81 | SCN9A (0.37) | GABRA5HDAC6SCN9ASCN5A | |
| SCHEMBL808240 | 0.80 | HDAC6 (0.35) | HDAC4HDAC8HDAC6 | |
| SCHEMBL808234 | 0.80 | HDAC6 (0.34) | HDAC4HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012035023-A1 | TRIAZINE-OXADIAZOLES | NOVARTIS AG (CH) | 2012-03-22 | — | — | WO | disclosed |