SCHEMBL8079008

SCHEMBL8079008

Cc1ccc(S(=O)(=O)c2ccc(C)cc2CCl)c(CCl)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.40
NPSR1 Q6W5P4 1/20 0.40
GAA P10253 1/20 0.37
MEP1B Q16820 1/20 0.35
TAAR1 Q96RJ0 1/20 0.34
RAPGEF4 Q8WZA2 2/20 0.34
HTT P42858 2/20 0.34
TDP1 Q9NUW8 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
ALDH1A1 P00352 3/20 0.33
POLB P06746 2/20 0.33
MAPT P10636 2/20 0.33
HPGD P15428 1/20 0.33
ALOX12 P18054 1/20 0.33
GFER P55789 1/20 0.33
UBE2N P61088 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
AMY1A P0DUB6 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9820115 0.85 TAAR1 (0.36) KMT2AGAAMEP1BTAAR1RAPGEF4
SCHEMBL4138945 0.83 RAPGEF4 (0.42) KMT2AGAAMEP1BTAAR1RAPGEF4
SCHEMBL4339546 0.82 GAA (0.44) KMT2ANPSR1GAAMEP1BL3MBTL1
Methylamine SCHEMBL28132703 0.80 RAPGEF4 (0.41) KMT2AGAAMEP1BTAAR1RAPGEF4
SCHEMBL11680272 0.80 MEP1B (0.38) KMT2AGAAMEP1BTAAR1RAPGEF4
SCHEMBL2914223 0.78 TRPV4 (0.39) KMT2AGAAHTTALDH1A1POLB
SCHEMBL9820124 0.77 CNR2 (0.39) KMT2AGAAHTTTDP1L3MBTL1
SCHEMBL6544653 0.77 GAA (0.34) KMT2AGAAMEP1BTAAR1RAPGEF4
SCHEMBL3948236 0.76 PSEN1 (0.41) KMT2ASMN1; SMN2
SCHEMBL3626865 0.76 POLB (0.44) KMT2AGAAL3MBTL1ALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0743574-B1 Migration imaging members XEROX CORP (US) 2000-12-27 EP claimed
EP-0743573-B1 Method for obtaining image contrast migration imaging members XEROX CORP (US) 2000-09-06 EP claimed
EP-0743573-A2 Method for obtaining image contrast migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
EP-0743574-A2 Migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
US-5514505-A SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE XEROX CORPORATION (US) 1996-05-07 US claimed
EP-0743574-B1 Migration imaging members XEROX CORP (US) 2000-12-27 EP disclosed
EP-0743573-B1 Method for obtaining image contrast migration imaging members XEROX CORP (US) 2000-09-06 EP disclosed
EP-0743573-A2 Method for obtaining image contrast migration imaging members XEROX CORPORATION (US) 1996-11-20 EP disclosed
EP-0743574-A2 Migration imaging members XEROX CORPORATION (US) 1996-11-20 EP disclosed
US-5563014-A SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT XEROX CORPORATION (US) 1996-10-08 US disclosed
US-5514505-A SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE XEROX CORPORATION (US) 1996-05-07 US disclosed