Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | CCR5 | P51681 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL808022 | 0.83 | LMNA (0.35) | GAA | |
| SCHEMBL808024 | 0.82 | TSHR (0.37) | — | |
| SCHEMBL808032 | 0.78 | DHFR (0.34) | — | |
| SCHEMBL808343 | 0.77 | SCD (0.34) | — | |
| SCHEMBL808223 | 0.77 | LMNA (0.43) | GAAKCNH2 | |
| SCHEMBL808232 | 0.77 | CNR2 (0.32) | — | |
| SCHEMBL808026 | 0.76 | — | — | |
| SCHEMBL808048 | 0.76 | LMNA (0.36) | GAAKCNH2 | |
| SCHEMBL807785 | 0.73 | HDAC4 (0.30) | HDAC4HDAC8HDAC6 | |
| SCHEMBL10286916 | 0.73 | ALDH1A1 (0.38) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012035023-A1 | TRIAZINE-OXADIAZOLES | NOVARTIS AG (CH) | 2012-03-22 | — | — | WO | disclosed |