Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SCD | O00767 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 2/20 | 0.31 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.31 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.31 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL808024 | 0.88 | TSHR (0.37) | SIGMAR1 | |
| SCHEMBL808232 | 0.86 | CNR2 (0.32) | SIGMAR1POLB | |
| SCHEMBL808343 | 0.83 | SCD (0.34) | SIGMAR1SCD | |
| SCHEMBL808046 | 0.78 | GAA (0.31) | — | |
| SCHEMBL807956 | 0.78 | PRCP (0.35) | SLC18A3 | |
| SCHEMBL808223 | 0.77 | LMNA (0.43) | — | |
| SCHEMBL10286918 | 0.77 | GAA (0.39) | — | |
| SCHEMBL807935 | 0.77 | SMN1; SMN2 (0.41) | — | |
| SCHEMBL10286916 | 0.76 | ALDH1A1 (0.38) | — | |
| SCHEMBL808034 | 0.75 | GAA (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012035023-A1 | TRIAZINE-OXADIAZOLES | NOVARTIS AG (CH) | 2012-03-22 | — | — | WO | disclosed |