SCHEMBL8080246

SCHEMBL8080246

CCCCC(C)Oc1cc(OC(C)=O)cc(OC(C)CCCC)c1OC(C)CCCC

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.49
KDM4E B2RXH2 2/20 0.37
ALDH1A1 P00352 1/20 0.37
LMNA P02545 1/20 0.37
TP53 P04637 1/20 0.37
GLA P06280 1/20 0.37
GAA P10253 1/20 0.37
MAPT P10636 1/20 0.37
MAPK1 P28482 1/20 0.37
CASP1 P29466 1/20 0.37
HTT P42858 1/20 0.37
CASP7 P55210 1/20 0.37
HSD17B10 Q99714 1/20 0.37
GPR88 Q9GZN0 1/20 0.36
LNPEP Q9UIQ6 2/20 0.35
PTGS2 P35354 2/20 0.35
CYP4F2 P78329 1/20 0.34
CYP4A11 Q02928 1/20 0.34
BACE1 P56817 1/20 0.34
PPARG P37231 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8081333 0.96 ALOX5 (0.51) ALOX5KDM4EALDH1A1LMNATP53
SCHEMBL8080238 0.94 ALOX5 (0.52) ALOX5KDM4EALDH1A1LMNATP53
SCHEMBL8086396 0.94 ALOX5 (0.52) ALOX5KDM4EALDH1A1LMNATP53
SCHEMBL8086442 0.91 ALOX5 (0.45) ALOX5KDM4EALDH1A1LMNATP53
SCHEMBL8086416 0.85 ALOX5 (0.43) ALOX5KDM4EALDH1A1LMNATP53
SCHEMBL8080297 0.84 KDM4E (0.43) ALOX5KDM4EALDH1A1LMNAGLA
SCHEMBL8072267 0.81 ALOX5 (0.44) ALOX5KDM4EALDH1A1LMNAMAPT
SCHEMBL8081214 0.79 PLA2G2A (0.42) ALDH1A1GPR88HTR2AHTR2CHTR2B
SCHEMBL8082106 0.79 GPR88 (0.49) ALDH1A1LMNAGAAMAPTHSD17B10
SCHEMBL8080243 0.77 THRB (0.50) ALDH1A1GAAHSD17B10GPR88LNPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0758013-B1 Liquid crystalline optical film, compensating film for liquid crystal display and liquid crystal display NIPPON OIL CO LTD (JP) 2000-10-11 EP disclosed
US-5855971-A Liquid crystalline optical film, compensating film for liquid crystal display comprising the liquid crystalline optical film, and liquid crystal display having the compensating film NIPPON OIL COMPANY, LIMITED (JP) 1999-01-05 US disclosed
EP-0758013-A1 Liquid crystalline optical film, compensating film for liquid crystal display and liquid crystal display NIPPON OIL COMPANY, LIMITED (JP) 1997-02-12 EP disclosed