SCHEMBL8080255

SCHEMBL8080255

CC(=O)Oc1ccc(CC(=O)Oc2cc(OC(=O)Cc3ccc(OC(C)=O)cc3)cc(OC(=O)Cc3ccc(OC(C)=O)cc3)c2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.54
LMNA P02545 3/20 0.53
MAPT P10636 2/20 0.53
KDM4E B2RXH2 2/20 0.53
MEN1 O00255 1/20 0.53
TTR P02766 1/20 0.53
TP53 P04637 1/20 0.53
CYP3A4 P08684 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
L3MBTL1 Q9Y468 2/20 0.50
GAA P10253 1/20 0.49
CYP19A1 P11511 1/20 0.47
POLB P06746 2/20 0.46
PKM P14618 1/20 0.46
ATM Q13315 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
ELANE P08246 2/20 0.44
ASAH1 Q13510 1/20 0.44
ALDH1A1 P00352 1/20 0.44
CYP4F2 P78329 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24819498 0.88 LMNA (0.69) KMT2ALMNAMAPTL3MBTL1GAA
SCHEMBL8081076 0.85 L3MBTL1 (0.50) KMT2ALMNAMAPTKDM4EMEN1
SCHEMBL4406559 0.84 CYP4F2 (0.58) KMT2ALMNAMAPTKDM4EL3MBTL1
SCHEMBL718523 0.81 MAPT (0.56) KMT2ALMNAMAPTKDM4EMEN1
SCHEMBL8037879 0.81 POLB (0.61) KMT2ALMNAMAPTKDM4EMEN1
SCHEMBL2416902 0.81 LIPE (0.54) KMT2ALMNAMAPTMEN1CYP3A4
SCHEMBL777803 0.81 ELANE (0.62) KMT2ALMNAMAPTKDM4EMEN1
SCHEMBL9081470 0.81 LMNA (0.61) KMT2ALMNAMAPTKDM4EMEN1
SCHEMBL384743 0.79 GAA (0.57) LMNAMAPTKDM4EGAAPOLB
SCHEMBL7964074 0.79 L3MBTL1 (0.62) KMT2ALMNAMAPTL3MBTL1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0758013-B1 Liquid crystalline optical film, compensating film for liquid crystal display and liquid crystal display NIPPON OIL CO LTD (JP) 2000-10-11 EP disclosed
US-5855971-A Liquid crystalline optical film, compensating film for liquid crystal display comprising the liquid crystalline optical film, and liquid crystal display having the compensating film NIPPON OIL COMPANY, LIMITED (JP) 1999-01-05 US disclosed
EP-0758013-A1 Liquid crystalline optical film, compensating film for liquid crystal display and liquid crystal display NIPPON OIL COMPANY, LIMITED (JP) 1997-02-12 EP disclosed