Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.72 |
| ▸ | ATM | Q13315 | 1/20 | 0.72 |
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.52 |
| ▸ | FNTA | P49354 | 3/20 | 0.52 |
| ▸ | FNTB | P49356 | 3/20 | 0.52 |
| ▸ | SQLE | Q14534 | 1/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5387180 | 1.00 | KDM4E (0.72) | KDM4EATMPOLBKMT2AALDH1A1 | |
| SCHEMBL1618744 | 1.00 | KDM4E (0.72) | KDM4EATMPOLBKMT2AALDH1A1 | |
| SCHEMBL13701615 | 0.96 | KMT2A (0.67) | KDM4EATMPOLBKMT2AALDH1A1 | |
| SCHEMBL9881031 | 0.96 | KMT2A (0.67) | KDM4EATMPOLBKMT2AALDH1A1 | |
| SCHEMBL10297986 | 0.96 | KMT2A (0.67) | KDM4EATMPOLBKMT2AALDH1A1 | |
| SCHEMBL11852033 | 0.96 | KMT2A (0.67) | KDM4EATMPOLBKMT2AALDH1A1 | |
| Citral SCHEMBL7771311 | 0.88 | ALDH1A1 (0.78) | KDM4EATMPOLBKMT2AALDH1A1 | |
| SCHEMBL794673 | 0.84 | KDM4E (1.00) | KDM4EATMPOLBKMT2AALDH1A1 | |
| SCHEMBL310619 | 0.84 | KDM4E (1.00) | KDM4EATMPOLBKMT2AALDH1A1 | |
| SCHEMBL29526077 | 0.84 | KDM4E (1.00) | KDM4EATMPOLBKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 151 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7923049-B2 | Compositions of oxo-terpene derivatives and process for preparing the same | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2011-04-12 | — | — | US | claimed |
| US-20090180972-A1 | COMPOSITIONS OF OXO-TERPENE DERIVATIVES AND PROCESS FOR PREPARING THE SAME | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2009-07-16 | — | — | US | claimed |
| EP-1417896-B1 | Fruit, berry, cranberry and hedonically-stable citrus flavored compositions and process for preparing same | INT FLAVORS & FRAGRANCES INC (US) | 2008-08-13 | — | — | EP | claimed |
| US-7176177-B2 | Aromas and aroma compositions containing 4,8-dimethyl-3,7-nonadien-2-one, and a method for the production thereof | SYMRISE GMBH & CO. KG (DE) | 2007-02-13 | — | — | US | claimed |
| US-7097872-B2 | Fruit, berry, cranberry and hedonically-stable citrus flavored compositions and process for preparing same | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2006-08-29 | — | — | US | claimed |
| US-20040091595-A1 | Fruit, berry, cranberry and hedonically-stable citrus flavored compositions and process for preparing same | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2004-05-13 | — | — | US | claimed |
| EP-1417896-A1 | Fruit, berry, cranberry and hedonically-stable citrus flavored compositions and process for preparing same | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2004-05-12 | — | — | EP | claimed |
| US-20030096731-A1 | Aromas and aroma compositions containing 4,8-dimethyl-3,7-nonadien-2-one, and a method for production thereof | SYMRISE AG (DE) | 2003-05-22 | — | — | US | claimed |
| EP-1248532-A1 | AROMAS AND AROMA COMPOSITIONS CONTAINING 4,8-DIMETHYL-3,7-NONADIEN-2-ONE | Symrise GmbH & Co. KG (DE) | 2002-10-16 | — | — | EP | claimed |
| US-20010005711-A1 | Perfume compositions comprising 4,8-dimethyl-3,7-nonadien-2-one | SYMRISE GMBH & CO. KG (DE) | 2001-06-28 | — | — | US | claimed |
| WO-2001043567-A1 | AROMAS AND AROMA COMPOSITIONS CONTAINING 4,8-DIMETHYL-3,7-NONADIEN-2-ONE, AND A METHOD FOR THE PRODUCTION THEREOF | HAARMANN & REIMER GMBH (DE) | 2001-06-21 | — | — | WO | claimed |
| US-3932462-A | Manufacture of unsaturated ketones | BASF AKTIENGESELLSCHAFT (DT) | 1976-01-13 | — | — | US | claimed |
| CN-117865784-A | Preparation method of alpha-damascone | 亳州优开生物医药科技有限公司 | 2024-04-12 | — | — | CN | disclosed |
| CN-117865784-A | Preparation method of alpha-damascone | 亳州优开生物医药科技有限公司 | 2024-04-12 | — | — | CN | disclosed |
| US-20240108040-A1 | HIGH INTENSITY SWEETENERS | FIRMENICH INCORPORATED (US) | 2024-04-04 | — | — | US | disclosed |
| US-11758933-B2 | High intensity sweeteners | FIRMENICH INCORPORATED (US) | 2023-09-19 | — | — | US | disclosed |
| WO-2001043567-A1 | AROMAS AND AROMA COMPOSITIONS CONTAINING 4,8-DIMETHYL-3,7-NONADIEN-2-ONE, AND A METHOD FOR THE PRODUCTION THEREOF | HAARMANN & REIMER GMBH (DE) | 2001-06-21 | — | — | WO | disclosed |
| WO-2001043567-A1 | AROMAS AND AROMA COMPOSITIONS CONTAINING 4,8-DIMETHYL-3,7-NONADIEN-2-ONE, AND A METHOD FOR THE PRODUCTION THEREOF | HAARMANN & REIMER GMBH (DE) | 2001-06-21 | — | — | WO | disclosed |
| US-3954804-A | Production of high molecular weight unsaturated ketones | BASF AKTIENGESELLSCHAFT (DT) | 1976-05-04 | — | — | US | disclosed |
| US-3932462-A | Manufacture of unsaturated ketones | BASF AKTIENGESELLSCHAFT (DT) | 1976-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030096731-A1 | Aromas and aroma compositions containing 4,8-dimethyl-3,7-nonadien-2-one, and a method for production thereof | TAS2R8, TAS2R7, TAS2R40 | KDM4E 106/4885ATM 3875/4885POLB 1951/4885 |
| US-20010005711-A1 | Perfume compositions comprising 4,8-dimethyl-3,7-nonadien-2-one | DEK, DPM1, DEGS1 | KDM4E 1351/4885ATM 3320/4885POLB 441/4885 |
| US-20240108040-A1 | HIGH INTENSITY SWEETENERS | TAS2R40, TAS2R60, TAS1R1 | KDM4E 3699/4885ATM 322/4885POLB 4295/4885 |
| US-11758933-B2 | High intensity sweeteners | TAS2R40, TAS2R60, TAS1R1 | KDM4E 3699/4885ATM 322/4885POLB 4295/4885 |
| US-20090180972-A1 | COMPOSITIONS OF OXO-TERPENE DERIVATIVES AND PROCESS FOR PREPARING THE SAME | OXER1, ALKBH3, ALKBH1 | KDM4E 2272/4885ATM 905/4885POLB 3909/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.