Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITK | Q08881 | 2/20 | 0.51 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 7/20 | 0.36 |
| ▸ | HCK | P08631 | 5/20 | 0.36 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 2/20 | 0.33 |
| ▸ | JAK3 | P52333 | 2/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL807946 | 0.83 | ITK (0.58) | ITKRORCDHODHLCKAURKB | |
| SCHEMBL10285825 | 0.83 | ITK (0.58) | ITKRORCDHODHLCKAURKB | |
| SCHEMBL807743 | 0.83 | ITK (0.57) | ITKRORCDHODHLCKAURKB | |
| SCHEMBL808093 | 0.83 | ITK (0.61) | ITKRORCDHODHLCKAURKB | |
| SCHEMBL807803 | 0.82 | ITK (0.58) | ITKRORCDHODHLCKAURKB | |
| SCHEMBL2395616 | 0.80 | ITK (0.56) | ITKRORCDHODHLCKAURKB | |
| SCHEMBL808081 | 0.80 | ITK (0.54) | ITKRORCDHODHLCKAURKB | |
| SCHEMBL807540 | 0.79 | ITK (0.46) | ITKRORCDHODHLCKAURKB | |
| SCHEMBL22374670 | 0.75 | ITK (0.71) | ITKRORCDHODHLCKAURKB | |
| SCHEMBL807926 | 0.73 | ITK (0.59) | ITKRORCDHODHLCKAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012035055-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2012-03-22 | — | — | WO | disclosed |