Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10287198 | 0.85 | HDAC6 (0.34) | HDAC4HDAC8HDAC6 | |
| SCHEMBL10287196 | 0.84 | HDAC4 (0.37) | HDAC4HDAC8HDAC6 | |
| SCHEMBL808332 | 0.83 | GABRA5 (0.34) | HDAC4HDAC8HDAC6 | |
| SCHEMBL808240 | 0.81 | HDAC6 (0.35) | HDAC4HDAC8HDAC6 | |
| SCHEMBL808036 | 0.80 | POLB (0.34) | — | |
| SCHEMBL10286912 | 0.79 | GABRA1 (0.36) | HDAC4HDAC8HDAC6 | |
| SCHEMBL808241 | 0.78 | HDAC6 (0.33) | HDAC4HDAC8HDAC6 | |
| SCHEMBL808234 | 0.77 | HDAC6 (0.34) | HDAC4HDAC8HDAC6 | |
| SCHEMBL807937 | 0.77 | GABRA5 (0.34) | — | |
| SCHEMBL808247 | 0.77 | STAT3 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012035023-A1 | TRIAZINE-OXADIAZOLES | NOVARTIS AG (CH) | 2012-03-22 | — | — | WO | disclosed |